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Original Articles

Lower proportion of CD19+IL-10+ and CD19+CD24+CD27+ but not CD1d+CD5+CD19+CD24+CD27+ IL-10+ B cells in children with autoimmune thyroid diseases

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Pages 46-55 | Received 11 Aug 2019, Accepted 22 Nov 2019, Published online: 02 Dec 2019

References

  • Antonelli A, Ferrari SM, Corrado A, et al. Autoimmune thyroid disorders. Autoimmun Rev. 2015;14:174–180.
  • Committee on Pharmaceutical Affairs, Japanese Society for Pediatric Endocrinology, and the Pediatric Thyroid Disease Committee, Japan Thyroid Association (Taskforce for the Revision of the Guidelines for the Treatment of Childhood-Onset Graves’ Disease); Minamitani K, Sato H, Ohye H, et al. Guidelines for the treatment of childhood-onset Graves' disease in Japan 2016. Clin Pediatr Endocrinol. 2017;26:29–62.
  • De Luca F, Santucci S, Corica D, et al. Hashimoto's thyroiditis in childhood: presentation modes and evolution over time. Ital J Pediatr. 2013;39:8.
  • Bossowski AT, Reddy V, Perry LA, et al. Clinical and endocrine features and long-term outcome of Graves' disease in early childhood. J Endocrinol Invest. 2007;5:388–392.
  • Lee HJ, Li CW, Hammerstad SS, et al. Immunogenetics of autoimmune thyroid diseases: A comprehensive review. J Autoimmun. 2015;64:82–90.
  • Saranac L, Zivanovic S, Bjelakovic B, et al. Why is the thyroid so prone to autoimmune disease? Horm Res Paediatr. 2011;75:157–165.
  • Bossowski A, Moniuszko M, Dąbrowska M, et al. Lower proportions of CD4 + CD25(high) and CD4 + FoxP3, but not CD4 + CD25 + CD127(low) FoxP3+ T cell levels in children with autoimmune thyroid diseases. Autoimmunity. 2013;46:222–230.
  • Bossowski A, Moniuszko M, Idźkowska E, et al. Decreased proportions of CD4 + IL17+/CD4 + CD25 + CD127- and CD4 + IL17+/CD4 + CD25 + CD127 - FoxP3+ T cells in children with autoimmune thyroid diseases. Autoimmunity. 2016;49:320–328.
  • Ramos-Leví AM, Marazuela M. Pathogenesis of thyroid autoimmune disease: the role of cellular mechanisms. Endocrinol Nutr. 2016;63:421–429.
  • Bliddal S, Nielsen CH, Feldt-Rasmussen U. Recent advances in understanding autoimmune thyroid disease: the tallest tree in the forest of polyautoimmunity. F1000Res. 2017;6:1776.
  • Wang B, Shao X, Song R, et al. The emerging role of epigenetics in autoimmune thyroid diseases. Front Immunol. 2017;8:396.
  • Phenekos C, Vryonidou A, Gritzapis AD, et al. Th1 and Th2 serum cytokine profiles characterize patients with Hashimoto’s thyroiditis (Th1) and Graves' disease (Th2). Neuroimmunomodulation. 2004;11:209–213.
  • Mauri C, Blair PA. Regulatory B cells in autoimmunity: developments and controversies. Nat Rev Rheumatol. 2010;6:636–643.
  • Wang P, Zheng SG. Regulatory T cells and B cells: implication on autoimmune diseases. Int J Clin Exp Pathol. 2013;6:2668–2674.
  • Kalampokis I, Yoshizaki A, Tedder TF. IL-10-producing regulatory B cells (B10 cells) in autoimmune disease. Arthritis Res Ther. 2013;15:S1.
  • Lykken JM, Candando KM, Tedder TF. Regulatory B10 cell development and function. Int Immunol. 2015;27:471–477.
  • Mann MK, Ray A, Basu S, et al. Pathogenic and regulatory roles for B cells in experimental autoimmune encephalomyelitis. Autoimmunity. 2012;45:388–399.
  • Pillai S, Mattoo H, Cariappa A. B cells and autoimmunity. Curr Opin Immunol. 2011;23:721–731.
  • Iyer SS, Cheng G. Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease. Crit Rev Immunol. 2012;32:23–63.
  • Iwata Y, Matsushita T, Horikawa M, et al. Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood. 2011;117:530–541.
  • Blair PA, Noreña LY, Flores-Borja F, et al. CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients. Immunity. 2010;32:129–140.
  • Kristensen B. Regulatory B and T cell responses in patients with autoimmune thyroid disease and healthy controls. Dan Med J. 2016;63.
  • Zha B, Wang L, Liu X, et al. Decrease in proportion of CD19+ CD24(hi) CD27+ B cells and impairment of their suppressive function in Graves' disease. PLoS One. 2012;7:e49835.
  • Kalampokis I, Venturi GM, Poe JC, et al. The regulatory B cell compartment expands transiently during childhood and is contracted in children with autoimmunity. Arthritis Rheumatol. 2017;69:225–238.
  • Zahran A, Aly S, Elabd A, et al. Regulatory and memory B lymphocytes in children with newly diagnosed immune thrombocytopenia. J Hematol. 2017;6:81–86.
  • Mason D, Powrie F. Control of immune pathology by regulatory T cells. Curr Opin Immunol. 1998;6:649–655.
  • Hussain S, Delovitch TL. Intravenous transfusion of BCR-activated B cells protects NOD mice from type 1 diabetes in an IL-10-dependent manner. J Immunol. 2007;179:7225–7232.
  • Matsushita T, Yanaba K, Bouaziz JD, et al. Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression. J Clin Invest. 2008;118:3420–3430.
  • Mauri C, Gray D, Mushtaq N, et al. Prevention of arthritis by interleukin 10-producing B cells. J Exp Med. 2003;197:489–501.
  • Rosser EC, Mauri C. Regulatory B cells: origin, phenotype, and function. Immunity. 2015;42:607–612.
  • Bossowski A, Harasymczuk J, Moniuszko A, et al. Cytometric evaluation of intracellular IFN-γ and IL-4 levels in thyroid follicular cells from patients with autoimmune thyroid diseases. Thyroid Res. 2011;4:13.
  • Mizoguchi A, Bhan AK. A case for regulatory B cells. J Immunol. 2006;176:705–710.
  • Mauri C, Menon M. Human regulatory B cells in health and disease: therapeutic potential. J Clin Invest. 2017;127:772–779.
  • He Y, Qian H, Liu Y, et al. The roles of regulatory B cells in cancer. J Immunol Res. 2014;2014:215471.
  • Zhang Y, Gallastegui N, Rosenblatt JD. Regulatory B cells in anti-tumor immunity. Int ImmUNOL. 2015;27:521–530.
  • Katz SI, Parker D, Turk JL. B-cell suppression of delayed hypersensitivity reactions. Nature. 1974;251:550–551.
  • Wolf SD, Dittel BN, Hardardottir F, et al. Experimental Autoimmune Encephalomyelitis Induction in Genetically B Cell–deficient Mice. J Exp Med. 1996;184:2271–2278.
  • Yang M, Sun L, Wang S, et al. Cutting edge: novel function of B cell-activating factor in the induction of IL-10–producing regulatory B cells. J Immunol. 2010;184:3321–3325.
  • Peng B, Ming Y, Yang C. Regulatory B cells: the cutting edge of immune tolerance in kidney transplantation. Cell Death Dis. 2018;9:109.
  • Wortel CM, Heidt S. Regulatory B cells: phenotype, function and role in transplantation. Transpl Immunol. 2017;41:1–9.
  • Sarvaria A, Madrigal JA, Saudemont A. B cell regulation in cancer and anti-tumor immunity. Cell Mol Immunol. 2017;14:662–674.
  • Schwartz M, Zhang Y, Rosenblatt JD. B cell regulation of the anti-tumor response and role in carcinogenesis. J Immunother Cancer. 2016;4:40
  • Jin L, Weiqian C, Lihuan Y. Peripheral CD24hiCD27+CD19+B cells subset as a potential biomarker in naïve systemic lupus erythematosus. Int J Rheum Dis. 2013;16:698–708.
  • Couper KN, Blount DG, Riley EM. IL-10: the master regulator of immunity to infection. J Immunol. 2008;180:5771–5777.
  • Gallego-Valle J, Pérez-Fernández VA, Correa-Rocha R, et al. Generation of human Breg-like phenotype with regulatory function in vitro with bacteria-derived oligodeoxynucleotides. Int J Mol Sci. 2018;19:1737.
  • Kawashima A, Tanigawa K, Akama T, et al. Innate immune activation and thyroid autoimmunity. J Clin Endocrinol Metab. 2011;96:3661–3367.
  • Liu J, Fu J, Xu Y, et al. Antithyroid drug therapy for Graves' disease and implications for recurrence. Int J Endocrinol. 2017;2017:1.