Advanced search
Publication Cover
Autoimmunity Volume 54, 2021 - Issue 3
Submit an article Journal homepage
128
Views
0
CrossRef citations to date
0
Altmetric
Original Articles

Progesterone decreased indoleamine 2,3-dioxygenase 1(IDO1) expression in early pregnancy chorionic villi and decidua

Minyan Yanga Hospital Affiliated 5 to Nantong University (Taizhou People's Hospital), Taizhou, ChinaView further author information
,
Guanyou Huangb Reproductive Medicine Center, Department of Obstetrics and Gynecology, The affiliated Hospital of Guizhou Medical University, Guiyang, ChinaView further author information
,
Hua Qianb Reproductive Medicine Center, Department of Obstetrics and Gynecology, The affiliated Hospital of Guizhou Medical University, Guiyang, ChinaView further author information
,
Jun Wangb Reproductive Medicine Center, Department of Obstetrics and Gynecology, The affiliated Hospital of Guizhou Medical University, Guiyang, ChinaView further author information
,
Shuyun Zhaob Reproductive Medicine Center, Department of Obstetrics and Gynecology, The affiliated Hospital of Guizhou Medical University, Guiyang, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-7061-2318View further author information
ORCID Icon,
Shixiang Lib Reproductive Medicine Center, Department of Obstetrics and Gynecology, The affiliated Hospital of Guizhou Medical University, Guiyang, ChinaView further author information
&
Yan Yuanc Guizhou Provincial People's Hospital, Guiyang, ChinaView further author information
 show all
Pages 156-162 | Received 22 Dec 2020, Accepted 20 Mar 2021, Published online: 01 Apr 2021

References

  • Otani Y, Ichii O, Otsuka-Kanazawa S, et al. MRL/MpJ-Fas(lpr) mice show abnormalities in ovarian function and morphology with the progression of autoimmune disease. Autoimmunity. 2015;48(6):402–411.
  • Kudo Y, Boyd CA, Spyropoulou I, et al. Indoleamine 2,3-dioxygenase: distribution and function in the developing human placenta. J Reprod Immunol. 2004;61(2):87–98.
  • Ball HJ, Yuasa HJ, Austin CJ, et al. Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway. Int J Biochem Cell Biol. 2009;41(3):467–471.
  • Mbongue JC, Nicholas DA, Torrez TW, et al. The role of indoleamine 2, 3-dioxygenase in immune suppression and autoimmunity. Vaccines. 2015;3(3):703–729.
  • Kudo Y. The role of placental indoleamine 2,3-dioxygenase in human pregnancy. Obstet Gynecol Sci. 2013;56(4):209–216.
  • Heikkinen J, Möttönen M, Komi J, et al. Phenotypic characterization of human decidual macrophages. Clin Exp Immunol. 2003;131(3):498–505.
  • Sedlmayr P, Blaschitz A, Wintersteiger R, et al. Localization of indoleamine 2,3-dioxygenase in human female reproductive organs and the placenta. Mol Hum Reprod. 2002;8(4):385–391.
  • Kudo Y, Koh I, Sugimoto J. Localization of indoleamine 2,3-dioxygenase-1 and indoleamine 2,3-dioxygenase-2 at the human maternal-fetal interface. Int J Tryptophan Res. 2020;13:1178646920984163.
  • Cohen RA, Check JH, Dougherty MP. Evidence that exposure to progesterone alone is a sufficient stimulus to cause a precipitous rise in the immunomodulatory protein the progesterone induced blocking factor (PIBF). J Assist Reprod Genet. 2016;33(2):221–229.
  • Bianchi P, Leandro RM, Poscai AN, et al. Progesterone decreases in vitro indoleamine 2, 3-dioxygenase expression in dendritic and CD4+ cells from maternal–fetal interface of rats. Immunol Invest. 2017;46(5):447–459.
  • Mellor AL, Munn DH. Tryptophan catabolism prevents maternal T cells from activating lethal anti-fetal immune responses. J Reprod Immunol. 2001;52(1-2):5–13.
  • Mellor AL, Munn DH. Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation? Immunol Today. 1999;20(10):469–473.
  • Munn DH, Zhou M, Attwood JT, et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science. 1998;281(5380):1191–1193.
  • Zong S, Li C, Luo C, et al. Dysregulated expression of IDO may cause unexplained recurrent spontaneous abortion through suppression of trophoblast cell proliferation and migration. Sci Rep. 2016; 6:19916
  • Santillan MK, Pelham CJ, Ketsawatsomkron P, et al. Pregnant mice lacking indoleamine 2,3-dioxygenase exhibit preeclampsia phenotypes. Physiol Rep. 2015;3(1):e12257.
  • Hönig A, Rieger L, Kapp M, et al. Indoleamine 2,3-dioxygenase (IDO) expression in invasive extravillous trophoblast supports role of the enzyme for materno-fetal tolerance. J Reprod Immunol. 2004;61(2):79–86.
  • Liu W, Huang Y, Huang G, et al. Relationship of SOCS3 and TGF-β with IDO expression in early pregnancy chorionic villi and decidua. Exp Ther Med. 2017;14(5):4817–4824.
  • Li S, Zhao S, Luo J, et al. Estrogen induces indoleamine 2,3-dioxygenase expression via suppressors of cytokine signaling 3 in the chorionic villi and decidua of women in early pregnancy. Am J Reprod Immunol. 2020;83(1):e13197.
  • Saleem MA, Jha P, Buckshee K, et al. Studies on the immunosuppressive role of steroid hormones during pregnancy. Immunol Invest. 1992;21(1):1–10.
  • Stites DP, Siiteri PK. Steroids as immunosuppressants in pregnancy. Immunol Rev. 1983; 75:117–138.
  • Goldman S, Weiss A, Shalev E. The effect of progesterone on gelatinase expression in the decidua and fetal membranes before and after contractions. Am J Obstet Gynecol. 2007;197(5):521.e1–521.e7. 521.e5217.
  • Wong AH, Agrawal N, Hughes GC. Altered IgG autoantibody levels and CD4(+) T cell subsets in lupus-prone Nba2 mice lacking the nuclear progesterone receptor. Autoimmunity. 2015;48(6):389–401.
  • Garcia-Ruíz G, Flores-Espinosa P, Preciado-Martínez E, et al. In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1β, TNFα, IL-6, IL-8, IL-10. Reprod Biol Endocrinol. 2015;13(1):115.
  • Piccinni MP, Maggi E, Romagnani S. Role of hormone-controlled T-cell cytokines in the maintenance of pregnancy. Biochem Soc Trans. 2000;28(2):212–215.
  • Laumet G, Edralin JD, Chiang AC, et al. Resolution of inflammation-induced depression requires T lymphocytes and endogenous brain interleukin-10 signaling. Neuropsychopharmacology. 2018;43(13):2597–2605.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.