LncRNA XIST restrains the activation of Müller cells and inflammation in diabetic retinopathy via stabilizing SIRT1

References

• Ting DS, Cheung GC, Wong TY. Diabetic retinopathy: global prevalence, major risk factors, screening practices and public health challenges: a review. Clin Exp Ophthalmol. 2016;44(4):260–277.
   PubMed Web of Science ®Google Scholar
• Huang Q, Li J. Research progress of lncRNAs in diabetic retinopathy. Eur J Ophthalmol. 2020;31(4): 401.
   Web of Science ®Google Scholar
• Wong TY, Cheung CM, Larsen M, et al. Diabetic retinopathy. Nat Rev Dis Primers. 2016;2:16012.
   PubMed Web of Science ®Google Scholar
• Toft-Kehler AK, Gurubaran IS, Desler C, et al. Oxidative stress-induced dysfunction of Müller cells during starvation. Invest Ophthalmol Vis Sci. 2016;57(6):2721–2728.
   PubMed Web of Science ®Google Scholar
• Li XJ. Long non-coding RNA nuclear paraspeckle assembly transcript 1 inhibits the apoptosis of retina Müller cells after diabetic retinopathy through regulating miR-497/brain-derived neurotrophic factor axis. Diab Vasc Dis Res. 2018;15(3):204–213.
   PubMed Web of Science ®Google Scholar
• Coughlin BA, Feenstra DJ, Mohr S. Müller cells and diabetic retinopathy. Vision Res. 2017;139:93–100.
   PubMed Web of Science ®Google Scholar
• Tu Y, Zhu M, Wang Z, et al. Melatonin inhibits Müller cell activation and pro-inflammatory cytokine production via upregulating the MEG3/miR-204/Sirt1 axis in experimental diabetic retinopathy. J Cell Physiol. 2020;235(11):8724–8735.
   PubMed Web of Science ®Google Scholar
• Batista PJ, Chang HY. Long noncoding RNAs: cellular address codes in development and disease. Cell. 2013;152(6):1298–1307.
   PubMed Web of Science ®Google Scholar
• Hu C, Sun Y, Yang X. Pioglitazone up-regulates MALAT1 and promotes the proliferation of endothelial progenitor cells through increasing c-Myc expression in type 2 diabetes mellitus. Aging Pathol Thera. 2020;2(1):38–44.
   Google Scholar
• Li F, Wen X, Zhang H, et al. Novel insights into the role of long noncoding RNA in ocular diseases. Int J Mol Sci. 2016;17(4):478.
   PubMed Web of Science ®Google Scholar
• Yang Z, Jiang X, Jiang X, et al. X-inactive-specific transcript: a long noncoding RNA with complex roles in human cancers. Gene. 2018;679:28–35.
   PubMed Web of Science ®Google Scholar
• Zhang XT, Pan SX, Wang AH, et al. Long Non-Coding RNA (lncRNA) X-Inactive specific transcript (XIST) plays a critical role in predicting clinical prognosis and progression of colorectal cancer. Med Sci Monit. 2019;25:6429–6435.
   PubMed Web of Science ®Google Scholar
• Feng Y, Wan P, Yin L. Long noncoding RNA X-Inactive specific transcript (XIST) promotes osteogenic differentiation of periodontal ligament stem cells by sponging MicroRNA-214-3p. Med Sci Monit. 2020;26:e918932.
   PubMed Web of Science ®Google Scholar
• Li J, Wei L, Han Z, et al. Long non-coding RNA X-inactive specific transcript silencing ameliorates primary graft dysfunction following lung transplantation through microRNA-21-dependent mechanism. EBioMedicine. 2020;52:102600.
   PubMed Web of Science ®Google Scholar
• Dong Y, Wan G, Peng G, et al. Long non-coding RNA XIST regulates hyperglycemia-associated apoptosis and migration in human retinal pigment epithelial cells. Biomed Pharmacother. 2020;125:109959.
   PubMed Web of Science ®Google Scholar
• Rine J, Strathern JN, Hicks JB, et al. A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: evidence for and identification of cryptic mating-type loci. Genetics. 1979;93(4):877–901.
   PubMed Web of Science ®Google Scholar
• Strycharz J, Rygielska Z, Swiderska E, et al. SIRT1 as a therapeutic target in diabetic complications. Curr Med Chem. 2018;25(9):1002–1035.
   PubMed Web of Science ®Google Scholar
• Devi TS, Somayajulu M, Kowluru RA, et al. TXNIP regulates mitophagy in retinal Müller cells under high-glucose conditions: implications for diabetic retinopathy. Cell Death Dis. 2017;8(5):e2777.
   PubMedGoogle Scholar
• Duarte DA, Rosales MA, Papadimitriou A, et al. Polyphenol-enriched cocoa protects the diabetic retina from glial reaction through the sirtuin pathway. J Nutr Biochem. 2015;26(1):64–74.
   PubMed Web of Science ®Google Scholar
• Hachisu M, Hashizume M, Kawai H, et al. Finding prodromal frailty in a community-dwelling healthy older cohort by survey of BDNF or hand grip strength classified by BMI. APT. 2020;2(3):155–161.
   Google Scholar
• Zhao D, Zhao Y, Wang J, et al. Long noncoding RNA Hotair facilitates retinal endothelial cell dysfunction in diabetic retinopathy. Clin Sci. 2020;134(17):2419–2434.
   Web of Science ®Google Scholar
• Ke N, Pi LH, Liu Q, et al. Long noncoding RNA SNHG7 inhibits high glucose-induced human retinal endothelial cells angiogenesis by regulating miR-543/SIRT1 axis. Biochem Biophys Res Commun. 2019;514(2):503–509.
   PubMed Web of Science ®Google Scholar
• Toraih EA, Abdelghany AA, Abd El Fadeal NM, et al. Deciphering the role of circulating lncRNAs: RNCR2, NEAT2, CDKN2B-AS1, and PVT1 and the possible prediction of anti-VEGF treatment outcomes in diabetic retinopathy patients. Graefes Arch Clin Exp Ophthalmol. 2019;257(9):1897–1913.
   PubMed Web of Science ®Google Scholar
• Sun Y, Liu YX. LncRNA HOTTIP improves diabetic retinopathy by regulating the p38-MAPK pathway. Eur Rev Med Pharmacol Sci. 2018;22(10):2941–2948.
   PubMed Web of Science ®Google Scholar
• Yang J, Chen C, McLaughlin T, et al. Loss of X-box binding protein 1 in muller cells augments retinal inflammation in a mouse model of diabetes. Diabetologia. 2019;62(3):531–543.
   PubMed Web of Science ®Google Scholar
• Wang J, He C, Zhou T, et al. NGF increases VEGF expression and promotes cell proliferation via ERK1/2 and AKT signaling in Muller cells. Mol Vis. 2016;22:254–263.
   PubMed Web of Science ®Google Scholar
• Calderon GD, Juarez OH, Hernandez GE, et al. Oxidative stress and diabetic retinopathy: development and treatment. Eye. 2017;31(8):1122–1130.
   PubMed Web of Science ®Google Scholar
• Biswas S, Sarabusky M, Chakrabarti S. Diabetic retinopathy, lncRNAs, and inflammation: a dynamic, interconnected network. J Clin Med. 2019;8(7):1033.
   PubMed Web of Science ®Google Scholar
• Luo R, Xiao F, Wang P, et al. lncRNA H19 sponging miR-93 to regulate inflammation in retinal epithelial cells under hyperglycemia via XBP1s. Inflamm Res. 2020;69(3):255–265.
   PubMed Web of Science ®Google Scholar
• Jiang L, Wang C, Shen X. LncRNA GAS5 suppresses ER stress-induced apoptosis and inflammation by regulating SERCA2b in HG-treated retinal epithelial cell. Mol Med Rep. 2020;22(2):1072–1080.
   PubMed Web of Science ®Google Scholar
• Thomas AA, Biswas S, Feng B, et al. lncRNA H19 prevents endothelial-mesenchymal transition in diabetic retinopathy. Diabetologia. 2019;62(3):517–530.
   PubMed Web of Science ®Google Scholar
• Zhang X, Shi E, Yang L, et al. LncRNA AK077216 is downregulated in diabetic retinopathy and inhibited the apoptosis of retinal pigment epithelial cells by downregulating miR-383. Endocr J. 2019;66(11):1011–1016.
   PubMed Web of Science ®Google Scholar
• Zhang X, Zou X, Li Y, et al. Downregulation of lncRNA BANCR participates in the development of retinopathy among diabetic patients. Exp Ther Med. 2019;17(5):4132–4138.
   PubMed Web of Science ®Google Scholar
• Ren J, Dominguez LJ, Sowers JR, et al. Troglitazone attenuates high-glucose-induced abnormalities in relaxation and intracellular calcium in rat ventricular myocytes. Diabetes. 1996;45(12):1822–1825.
   PubMed Web of Science ®Google Scholar
• Ren J, Dominguez LJ, Sowers JR, et al. Metformin but not glyburide prevents high glucose-induced abnormalities in relaxation and intracellular Ca2+ transients in adult rat ventricular myocytes. Diabetes. 1999;48(10):2059–2065.
   PubMed Web of Science ®Google Scholar
• Tsai YC, Kuo MC, Hung WW, Wu LY, et al. High glucose induces mesangial cell apoptosis through miR-15b-5p and promotes diabetic nephropathy by extracellular vesicle delivery. Mol Ther. 2020;28(3):963–974.
   PubMed Web of Science ®Google Scholar
• Wang Q. XIST silencing alleviated inflammation and mesangial cells proliferation in diabetic nephropathy by sponging miR-485. Arch Physiol Biochem. 2020;2020:1–7.
   Google Scholar
• Li Y, Yuan X, Shi Z, et al. LncRNA XIST serves as a diagnostic biomarker in gestational diabetes mellitus and its regulatory effect on trophoblast cell via mir-497-5p/FOXO1 axis. Cardiovasc Diagn Ther. 2021;11(3):716–725.
   Google Scholar
• Li C, Liu JH, Su J, et al. LncRNA XIST knockdown alleviates LPS-induced acute lung injury by inactivation of XIST/miR-132-3p/MAPK14 pathway: XIST promotes ALI via miR-132-3p/MAPK14 axis. Mol Cell Biochem. 2021.
   Web of Science ®Google Scholar
• Mishra M, Duraisamy AJ, Kowluru RA. Sirt1: a guardian of the development of diabetic retinopathy. Diabetes. 2018;67(4):745–754.
   PubMed Web of Science ®Google Scholar
• Bible E. Diabetic nephropathy: Sirt1 attenuates diabetic albuminuria. Nat Rev Nephrol. 2013;9(12):696.
   PubMedGoogle Scholar
• Balestrieri ML, Servillo L, Esposito A, et al. Poor glycaemic control in type 2 diabetes patients reduces endothelial progenitor cell number by influencing SIRT1 signalling via platelet-activating factor receptor activation. Diabetologia. 2013;56(1):162–172.
   PubMed Web of Science ®Google Scholar
• Chen J, Zhang B, Wong N, et al. Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth. Cancer Res. 2011;71(12):4138–4149.
   PubMed Web of Science ®Google Scholar
• Bae HJ, Noh JH, Kim JK, et al. MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT1 in hepatocellular carcinoma. Oncogene. 2014;33(20):2557–2567.
   PubMed Web of Science ®Google Scholar
• Xiong H, Ni Z, He J, et al. LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells. Oncogene. 2017;36(25):3528–3540.
   PubMed Web of Science ®Google Scholar
• Chattopadhyay T, Maniyadath B, Bagul HP, et al. Spatiotemporal gating of SIRT1 functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia. Proc Natl Acad Sci USA. 2020;117(12):6890–6900.
   PubMed Web of Science ®Google Scholar
• Ge X, Xu B, Xu W, et al. Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating SIRT1 expression. Aging. 2019;11(20):8745–8759.
   PubMedGoogle Scholar