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Original Articles

Circ_0114427 promotes LPS-induced septic acute kidney injury by modulating miR-495-3p/TRAF6 through the NF-κB pathway

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Pages 52-64 | Received 27 May 2021, Accepted 17 Oct 2021, Published online: 03 Nov 2021

References

  • Novosad SA, Sapiano MR, Grigg C, et al. Vital Signs: Epidemiology of Sepsis: Prevalence of Health Care Factors and Opportunities for Prevention. MMWR Morb Mortal Wkly Rep‌. 2016;65(33):864–869. 
  • Vincent J-L, Rello J, Marshall J, et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA. 2009;302(21):2323–2329.
  • Singbartl K, Kellum JA. AKI in the ICU: definition, epidemiology, risk stratification, and outcomes. Kidney Int. 2012;81(9):819–825.
  • Yegenaga I, Hoste E, Van Biesen W, et al. Clinical characteristics of patients developing ARF due to sepsis/systemic inflammatory response syndrome: results of a prospective study. Am J Kidney Dis. 2004;43(5):817–824.
  • Lopes JA, Jorge S, Resina C, et al. Acute renal failure in patients with sepsis. Crit Care. 2007;11(2):411.
  • Qu S, Yang X, Li X, et al. Circular RNA: a new star of noncoding RNAs. Cancer Lett. 2015;365(2):141–148.
  • Kristensen LS, Andersen MS, Stagsted LVW, et al. The biogenesis, biology and characterization of circular RNAs. Nat Rev Genet. 2019;20(11):675–691.
  • Zhang Z, Yang T, Xiao J. Circular RNAs: promising biomarkers for human diseases. EBioMedicine. 2018;34:267–274.
  • Brandenburger T, Salgado Somoza A, Devaux Y, et al. Noncoding RNAs in acute kidney injury. Kidney Int. 2018;94(5):870–881.
  • Li H, Zhang X, Wang P, et al. Knockdown of circ-FANCA alleviates LPS-induced HK2 cell injury via targeting miR-93-5p/OXSR1 axis in septic acute kidney injury. Diabetol Metab Syndr. 2021;13(1):7.
  • Shi Y, Sun CF, Ge WH, et al. Circular RNA VMA21 ameliorates sepsis-associated acute kidney injury by regulating miR-9-3p/SMG1/inflammation axis and oxidative stress. J Cell Mol Med. 2020;24(19):11397–11408.
  • Cao Y, Mi X, Zhang D, et al. Transcriptome sequencing of circular RNA reveals a novel circular RNA-has_circ_0114427 in the regulation of inflammation in acute kidney injury. Clin Sci. 2020;134(2):139–154.
  • Croce CM, Calin GA. miRNAs, cancer, and stem cell division. Cell. 2005;122(1):6–7.
  • Small EM, Olson EN. Pervasive roles of microRNAs in cardiovascular biology. Nature. 2011;469(7330):336–342.
  • Collino F, Bruno S, Incarnato D, et al. AKI recovery induced by mesenchymal stromal cell-derived extracellular vesicles carrying microRNAs. J Am Soc Nephrol. 2015;26(10):2349–2360.
  • White N, Khella H, Grigull J, et al. miRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215. Br J Cancer. 2011;105(11):1741–1749.
  • Yu G, Li H, Wang J, et al. miRNA-34a suppresses cell proliferation and metastasis by targeting CD44 in human renal carcinoma cells. J Urol. 2014;192(4):1229–1237.
  • Wang J-F, Yu M-L, Yu G, et al. Serum miR-146a and miR-223 as potential new biomarkers for sepsis. Biochem Biophys Res Commun. 2010;394(1):184–188.
  • Leelahavanichkul A, Somparn P, Panich T, et al. Serum miRNA-122 in acute liver injury induced by kidney injury and sepsis in CD-1 mouse models. Hepatol Res. 2015;45(13):1341–1352.
  • Kito N, Endo K, Ikesue M, et al. miRNA profiles of tubular cells: diagnosis of kidney injury. Biomed Res Int. 2015;2015:465479.
  • Wang N, Zhou Y, Jiang L, et al. Urinary microRNA-10a and microRNA-30d serve as novel, sensitive and specific biomarkers for kidney injury. PLOS One. 2012;7(12):e51140.
  • He Y, Sun Y, Peng J. Circ_0114428 regulates Sepsis-Induced kidney injury by targeting the miR-495-3p/CRBN axis. Inflammation. 2021;44(4):1464–1477.
  • Xie P. TRAF molecules in cell signaling and in human diseases. J Mol Signal. 2013;8(1):7.
  • Inoue J, Gohda J, Akiyama T, et al. NF-kappaB activation in development and progression of cancer. Cancer Sci. 2007;98(3):268–274.
  • Thomas R. The TRAF6-NF kappa B signaling pathway in autoimmunity: not just inflammation . Arthritis Res Ther. 2005;7(4):170–173.
  • Angus DC, van der Poll T. Van der poll T. Severe sepsis and septic shock. N Engl J Med. 2013;369(9):840–851.
  • Bone RC, Sprung CL, Sibbald WJ. Definitions for sepsis and organ failure. Crit Care Med. 1992;20(6):724–726.
  • Uchino S, Kellum JA, Bellomo R. Acute renal failure in critically ill patients: a multinational, multicenter study. Jama. 2005;294(7):813–818.
  • Oppert M, Engel C, Brunkhorst F-M, for the German Competence Network Sepsis (Sepnet), et al. Acute renal failure in patients with severe sepsis and septic shock—a significant independent risk factor for mortality: results from the German prevalence study. Nephrol Dial Transplant. 2007;23(3):904–909.
  • Bellomo R, Bagshaw S, Langenberg C, et al. Pre-renal azotemia: a flawed paradigm in critically ill septic patients? Contrib Nephrol. 2007;156:1–9.
  • Ishani A, Xue JL, Himmelfarb J, et al. Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephrol. 2009;20(1):223–228.
  • Deng W, Chen K, Liu S, et al. Silencing circular ANRIL protects HK-2 cells from lipopolysaccharide-induced inflammatory injury through up-regulating microRNA-9. Artif Cells Nanomed Biotechnol. 2019;47(1):3478–3484.
  • Lu M, Zhang Q, Deng M, et al. An analysis of human microRNA and disease associations. PLOS One. 2008;3(10):e3420.
  • Geekiyanage H, Jicha GA, Nelson PT, et al. Blood serum miRNA: non-invasive biomarkers for alzheimer's disease. Exp Neurol. 2012;235(2):491–496.
  • Backes C, Meese E, Keller A. Specific miRNA disease biomarkers in blood, serum and plasma: challenges and prospects. Mol Diagn Ther. 2016;20(6):509–518.
  • Volinia S, Galasso M, Costinean S, et al. Reprogramming of miRNA networks in cancer and leukemia. Genome Res. 2010;20(5):589–599.
  • Huang J, Sun Z, Yan W, et al. Identification of microRNA as sepsis biomarker based on miRNAs regulatory network analysis. Biomed Res Int. 2014;2014:594350.
  • Lan Y-F, Chen H-H, Lai P-F, et al. MicroRNA-494 reduces ATF3 expression and promotes AKI. J Am Soc Nephrol. 2012;23(12):2012–2023.
  • Roderburg C, Luedde M, Cardenas DV, et al. Circulating microRNA-150 serum levels predict survival in patients with critical illness and sepsis. PLOS One. 2013;8(1):e54612.
  • Fu D, Dong J, Li P, et al. MiRNA-21 has effects to protect kidney injury induced by sepsis. Biomed Pharmacother. 2017;94:1138–1144.
  • Li Y-F, Jing Y, Hao J, et al. MicroRNA-21 in the pathogenesis of acute kidney injury. Protein Cell. 2013;4(11):813–819.
  • Sun H, Li X, Fan L, et al. TRAF6 is upregulated in Colon cancer and promotes proliferation of Colon cancer cells. Int J Biochem Cell Biol. 2014;53:195–201.
  • Wu H, Arron JR. TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology. Bioessays. 2003;25(11):1096–1105.
  • Chung JY, Lu M, Yin Q, et al. Molecular basis for the unique specificity of TRAF6. Adv Exp Med Biol. 2007;597:122–130.
  • Mao R, Fan Y, Mou Y, et al. TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated smad-independent IKK/NF-κB and JNK/AP-1 activation. Cell Signal. 2011;23(1):222–227.
  • Starczynowski DT, Lockwood WW, Deléhouzée S, et al. TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer. J Clin Invest. 2011;121(10):4095–4105.
  • Tak PP, Firestein GS. NF-kappaB: a key role in inflammatory diseases. J Clin Invest. 2001;107(1):7–11.

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