CircVMA21 ameliorates lipopolysaccharide (LPS)-induced HK-2 cell injury depending on the regulation of miR-7-5p/PPARA

References

• Cohen J, Vincent JL, Adhikari NK, et al. Sepsis: a roadmap for future research. Lancet Infect Dis. 2015;15(5):581–614.
   PubMed Web of Science ®Google Scholar
• Poston JT, Koyner JL. Sepsis associated acute kidney injury. BMJ. 2019;364:k4891.
   PubMedGoogle Scholar
• Prowle JR. Sepsis-associated AKI. Clin J Am Soc Nephrol. 2018;13(2):339–342.
   PubMed Web of Science ®Google Scholar
• Hoste EAJ, Kellum JA, Selby NM, et al. Global epidemiology and outcomes of acute kidney injury. Nat Rev Nephrol. 2018;14(10):607–625.
   PubMed Web of Science ®Google Scholar
• Maloney PJ. Sepsis and septic shock. Emerg Med Clin North Am. 2013;31(3):583–600.
   PubMed Web of Science ®Google Scholar
• Ebbesen KK, Kjems J, Hansen TB. Circular RNAs: Identification, biogenesis and function. Biochim Biophys Acta. 2016;1859(1):163–168.
   PubMed Web of Science ®Google Scholar
• Kristensen LS, Andersen MS, Stagsted LVW, et al. The biogenesis, biology and characterization of circular RNAs. Nat Rev Genet. 2019;20(11):675–691.
   PubMed Web of Science ®Google Scholar
• Zhong Y, Du Y, Yang X, et al. Circular RNAs function as ceRNAs to regulate and control human cancer progression. Mol Cancer. 2018;17(1):79.
   PubMed Web of Science ®Google Scholar
• Zhou C, Liu HS, Wang FW, et al. circCAMSAP1 promotes tumor growth in colorectal cancer via the miR-328-5p/E2F1 axis. Mol Ther. 2020;28(3):914–928.
   PubMed Web of Science ®Google Scholar
• Tang Q, Chen Z, Zhao L, et al. Circular RNA hsa_circ_0000515 acts as a miR-326 sponge to promote cervical cancer progression through up-regulation of ELK1. Aging (Albany NY)). 2019;11(22):9982–9999.
   PubMedGoogle Scholar
• Wei W, Yao Y, Bi H, et al. Circular RNA circ_0068,888 protects against lipopolysaccharide-induced HK-2 cell injury via sponging microRNA-21-5p. Biochem Biophys Res Commun. 2021;540:1–7.
   PubMed Web of Science ®Google Scholar
• Shi X, Ma W, Li Y, et al. CircPRKCI relieves lipopolysaccharide-induced HK2 cell injury by upregulating the expression of miR-545 target gene ZEB2. Biofactors. 2020;46(3):475–486.
   PubMed Web of Science ®Google Scholar
• Shi Y, Sun CF, Ge WH, et al. Circular RNA VMA21 ameliorates sepsis-associated acute kidney injury by regulating miR-9-3p/SMG1/inflammation axis and oxidative stress. J Cell Mol Med. 2020;24(19):11397–11408.
   PubMed Web of Science ®Google Scholar
• Amiel J, de Pontual L, Henrion-Caude A. miRNA, development and disease. Adv Genet. 2012;80:1–36.
   PubMed Web of Science ®Google Scholar
• Xie Y, Zhang S, Lv Z, et al. SOX21-AS1 modulates neuronal injury of MMP(+)-treated SH-SY5Y cells via targeting miR-7-5p and inhibiting IRS2. Neurosci Lett. 2021;746:135602. )
   PubMed Web of Science ®Google Scholar
• Chen L, Shi J, Wu Y, et al. CircRNA CDR1as promotes hepatoblastoma proliferation and stemness by acting as a miR-7-5p sponge to upregulate KLF4 expression. Aging (Albany NY)). 2020;12(19):19233–19253.
   PubMedGoogle Scholar
• Zhang X, Niu W, Mu M, et al. Long non-coding RNA LPP-AS2 promotes glioma tumorigenesis via miR-7-5p/EGFR/PI3K/AKT/c-MYC feedback loop. J Exp Clin Cancer Res. 2020;39(1):196.
   PubMed Web of Science ®Google Scholar
• Zhong Q, Huang J, Wei J, et al. Circular RNA CDR1as sponges miR-7-5p to enhance E2F3 stability and promote the growth of nasopharyngeal carcinoma. Cancer Cell Int. 2019;19(1):252.
   PubMed Web of Science ®Google Scholar
• Deng JN, Li YQ, Liu Y, et al. Exosomes derived from plasma of septic patients inhibit apoptosis of T lymphocytes by down-regulating bad via hsa-miR-7-5p. Biochem Biophys Res Commun. 2019;513(4):958–966.
   PubMed Web of Science ®Google Scholar
• Iwaki T, Bennion BG, Stenson EK, et al. PPARα contributes to protection against metabolic and inflammatory derangements associated with acute kidney injury in experimental sepsis. Physiol Rep. 2019;7(10):e14078.
   PubMed Web of Science ®Google Scholar
• Beltran-Garcia J, Osca-Verdegal R, Nacher-Sendra E, et al. Circular RNAs in sepsis: biogenesis, function, and clinical significance. Cells. 2020;9(6):1544.
   PubMed Web of Science ®Google Scholar
• Wang J, Song J, Li Y, et al. Down-regulation of LncRNA CRNDE aggravates kidney injury via increasing MiR-181a-5p in sepsis. Int Immunopharmacol. 2020;79:105933.
   PubMed Web of Science ®Google Scholar
• Yang P, Gao R, Zhou W, et al. Protective impacts of circular RNA VMA21 on lipopolysaccharide-engendered WI-38 cells injury via mediating microRNA-142-3p. Biofactors. 2020;46(3):381–390.
   PubMed Web of Science ®Google Scholar
• Forbes JM, Coughlan MT, Cooper ME. Oxidative stress as a major culprit in kidney disease in diabetes. Diabetes. 2008;57(6):1446–1454.
   PubMed Web of Science ®Google Scholar
• Galley HF. Bench-to-bedside review: targeting antioxidants to mitochondria in sepsis. Crit Care. 2010;14(4):230.
   PubMed Web of Science ®Google Scholar
• Koyner JL, Sher Ali R, Murray PT. Antioxidants. Do they have a place in the prevention or therapy of acute kidney injury? Nephron Exp Nephrol. 2008;109(4):e109–e117.
   PubMedGoogle Scholar
• Li G, Huang M, Cai Y, et al. Circ-U2AF1 promotes human glioma via derepressing neuro-oncological ventral antigen 2 by sponging hsa-miR-7-5p. J Cell Physiol. 2019;234(6):9144–9155.
   PubMed Web of Science ®Google Scholar
• Gao D, Qi X, Zhang X, et al. Hsa_circRNA_0006528 as a competing endogenous RNA promotes human breast cancer progression by sponging miR-7-5p and activating the MAPK/ERK signaling pathway. Mol Carcinog. 2019;58(4):554–564.
   PubMed Web of Science ®Google Scholar
• Gao Y, Liu J, Huan J, et al. Downregulation of circular RNA hsa_circ_0000735 boosts prostate cancer sensitivity to docetaxel via sponging miR-7. Cancer Cell Int. 2020;20:334.
   PubMed Web of Science ®Google Scholar
• Guo W, Zhao L, Wei G, et al. Blocking circ_0013912 suppressed cell growth, migration and invasion of pancreatic ductal adenocarcinoma cells in vitro and in vivo partially through sponging miR-7-5p. Cancer Manag Res. 2020;12:7291–7303.
   PubMed Web of Science ®Google Scholar
• Standage SW, Bennion BG, Knowles TO, et al. PPARα augments heart function and cardiac fatty acid oxidation in early experimental polymicrobial sepsis. Am J Physiol Heart Circ Physiol. 2017;312(2):H239–H249.
   PubMed Web of Science ®Google Scholar
• Paumelle R, Haas JT, Hennuyer N, et al. Hepatic PPARα is critical in the metabolic adaptation to sepsis. J Hepatol. 2019;70(5):963–973.
   PubMed Web of Science ®Google Scholar