Restoration of Thymic Homeostasis in a Tumor-Bearing Host by in Vivo Administration of Medicinal Herb Tinospora Cordifolia

REFERENCES

• Lauerova L., Dusek L., Simickova M., Kocak I., Vagundova M., Zaloundrik J., Kovarik. K. Malignant melanoma associates with Th1/Th2 imbalance that coincides with disease progression and immunotherapy response. Neoplasma 2002; 49: 159, [CSA]
   PubMed Web of Science ®Google Scholar
• Marsot-Dupuch K., Quillard J., Meyohas M.C. Head and neck lesions in the immunocompromised host. Eur. Radiol. 2004; 14: E155, [CSA], [CROSSREF]
   Web of Science ®Google Scholar
• Zeimet A.G., Widschwendter M., Knabbe C., Fuchs D., Herold M., Muller-Holzner E., Daxenbichler G., Offner F.A., Dapunt O., March C. Ascitic interleukin-12 is an independent prognostic factor in ovarian cancer. J. Clin. Oncol. 1998; 16: 1861, [CSA]
   PubMed Web of Science ®Google Scholar
• Sato M., Goto S., Kaneko R., Ito M., Sato S., Takeuchi S. Impaired production of Th1 cytokines and increased frequency of Th2 subsets of PBMC from advanced cancer patients. Anticancer Res 1998; 18: 3951, [CSA]
   PubMed Web of Science ®Google Scholar
• Levey D.L., Srivastava P.K. Immunol. Today 1996; 17: 365, [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Ben-Effraim S. One hundred years of cancer immunotherapy: a critical appraisal. Tumor Biol. 1999; 20: 1, [CSA], [CROSSREF]
   Google Scholar
• Klein G. Comparative studies of mouse tumors with respect to their capacity for growth as ‘ascitic tumors’ and their average nucleic acid content. Exp. Cell. Res. 1951; 2: 518, [CSA], [CROSSREF]
   Web of Science ®Google Scholar
• Udaychander M., Meenakshi A., Muthiah R., Sivanandhan R. Tumor targeting potential of liposomes encapsulating Ga-67 and antibody to Dalton’s lymphoma associated antigen (anti-DLAA). Int. Radiat. Oncol. Biol. Phys. 1987; 13: 1713, [CSA]
   PubMed Web of Science ®Google Scholar
• Khynriam D., Prasad S.B. Cisplatin induced genotoxic effects and endogenous glutathione levels in mice bearing ascites Dalton’s lymphoma. Mutat. Res. 2003; 526: 9, [CSA]
   PubMed Web of Science ®Google Scholar
• Kumar A., Singh S.M. Effect of tumor growth on the blastogenic response of splenocytes: a role of macrophage derived nitric oxide. Immunol. Invest. 1996; 25: 413, [CSA]
   PubMed Web of Science ®Google Scholar
• Shanker A., Singh S.M., Sodhi A. Ascitic growth of a spontaneous transplantable T cell lymphoma induces thymic involution. 1. Alterations in the CD4/CD8 distribution in thymocytes. Tumor Biol. 2000; 21: 288, [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Parajuli P., Singh S.M., Kumar A., Sodhi A. Alterations in the tumoricidal functions of murine tumor-associated macrophages during progressive growth of a tumor in vivo. Cancer J. 1997; 10: 222, [CSA]
   Web of Science ®Google Scholar
• Parajuli P., Singh S.M. Ascitic growth of a T-cell lymphoma in mice alters the humoral and cellular response to exogenous antigens. Tumor Biol. 1997; 18: 104, [CSA]
   PubMedGoogle Scholar
• Shrivastava P., Singh S.M., Singh N. Activation of tumor associated macrophages by thymosin alpha1. Int. J. Immunopharmacol. Pathol. 2004; 17: 39, [CSA]
   Google Scholar
• Diwanay S., Chitre D., Patwardhan B. Immunoprotection by botanicals drugs in cancer chemotherapy. J. Ethanopharmacol. 2004; 90: 49, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Dahanukar S.A., Thatte U.M. Current status of Ayurveda in phytomedicine. Phytomedicine 1997; 4: 359, [CSA]
   PubMed Web of Science ®Google Scholar
• Singh S.S., Pandey S.C., Srivastava S., Gupta V.S., Patro B., Ghosh A.C. Chemistry and medicinal properties of Tinospora cordifolia (Guduchi). Ind. J. Pharmacol. 2003; 35: 83, [CSA]
   Google Scholar
• Singh N., Singh S.M., Shrivastava P. Immunomodulatory and antitumor actions of medicinal plant Tinospora cordifolia are mediated through activation of tumor-associated macrophages. Immunopharmacol. Immunotoxicol. 2004; 26: 145, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Singh S.M., Singh N., Shrivastava P. Effect of alcoholic extract of Ayurvedic herb Tinospora cordifolia of the proliferation and myeloid differentiation of bone marrow precursor cells in a tumor-bearing host. Fitoterapia 2005, in press[CSA]
   Web of Science ®Google Scholar
• Singh N., Singh S.M., Shrivastava P. Effect of “Tinospora Cordifolia” on the antitumor activity of tumor associated macrophages derived dendritic cells. Immunopharmacol. Immunotoxicol. 2005; 27: 1, [CSA]
   PubMed Web of Science ®Google Scholar
• Bharti A.C., Singh S.M. Gangliosides derived from T cell lymphoma inhibit bone marrow cell proliferation and differentiation. Int. Immunopharmacol. 2001; 1: 155, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assay. J. Immunol. Meth. 1983; 65: 55, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Singh M.P., Rai A.K., Singh S.M. Gender dimorphism in the progressive in vivo growth of a T cell lymphoma: involvement of cytokines and gonadal hormones. J. Reprod. Immunol. 2005; 65: 17, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Roy R., Singh S.M., Shanker A. Mechanism of thymocyte apoptosis induced by serum of tumor-bearing host: the molecular events involved and their inhibition by thymosin α-1. Int. J. Immunopharmacol. 2000; 22: 309, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Coligan J.E., Kruisbeek A.M., Margulies D.H., Shevach E.M., Strober S. Current Protocols in Immunology. John Wiley and Sons. 1994; I: 8–10
   Google Scholar
• Gray D.H., Ueno T., Chidgey A.P., Malin M., Goldberg G.L., Takahama Y., Boyd R.L. Controlling the thymic microenvironment. Curr. Opin. Immunol. 2005; 17: 137, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Henson S.M., Pido-Lopez J., Aspinall R. Reversal of thymic atrophy. Exp. Gerontol. 2004; 39: 673, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Haynes B.F., Hale L.P. The human thymus: a chimeric organ comprised of central and peripheral lymphoid components. Immunol. Res. 1998; 18: 175, [CSA]
   PubMed Web of Science ®Google Scholar
• Henriques-Pons A., DeMeis J., Cotta-De-Almeida V., Savino W., Araujo-gorge T.C. Fas and perforin are not required for thymus atrophy induced by Trypanosoma cruzi infection. Exp. Parasitol. 2004; 107: 1, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Shanker A., Singh S.M. Impairment of T cell functions with the progressive ascitic growth of a transplantable T cell lymphoma of spontaneous origin. FEMS Immunol. Med. Microbiol. 2000; 27: 247, [CSA]
   PubMedGoogle Scholar
• Zhou X., Gordon S.A., Kim Y.M., Hoffman R.A., Chen Y., Zhang X.R., Simmons R.L., Ford H.R. Nitric oxide induces thymocyte apoptosis via a Caspase-1-dependent mechanism. J. Immunol. 2000; 165: 1252, [CSA]
   PubMed Web of Science ®Google Scholar
• Douek D. C., Altmann D.M. T cell apoptosis and differential human leucocyte antigen class II expression in human thymus. Immunology 2000; 99: 249, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Zaitseva M., Kawamura T., Loomis R., Goldstein H., Blauvelt A., Golding H. Stromal-derived factor expression in the human thymus. J. Immunol. 2002; 168: 2609, [CSA]
   PubMed Web of Science ®Google Scholar
• Rodriguez-Galan M.D., Bream J.H., Farr A., Young H.A. Synergistic effect of IL-2, IL-12 and IL-18 on thymocyte apoptosis and Th1/Th2 cytokine expression. J. Immunol. 2005; 174: 2796, [CSA]
   PubMed Web of Science ®Google Scholar
• Nishimura T., Iwakabe K., Sekimoto M., Ohmi Y., Yahata T., Nakui M., Sato T., Habu S., Tashiro H., Sato M., Ohta A. Distinct role of antigen-specific T helper type 1 (Th1) and Th2 cells in tumor eradication in vivo. J. Exp. Med. 1999; 190: 617, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Bowen M.A., Lee R.K., Miragliotta G., Nam S.Y., Podack E.R. Structure and expression of murine CD 30 and its role in cytokine production. J. Immunol. 1996; 156: 442, [CSA]
   PubMed Web of Science ®Google Scholar
• Renz H., Domenico J., Gelfand E.W. IL-4 dependent upregulation of IL-4 receptor expression in murine T and B cells. J. Immunol. 1991; 146: 3049, [CSA]
   PubMed Web of Science ®Google Scholar
• Romagnani P., Annuziato F., Manetti R., Mavilia C. High CD 30 ligand expression by epithelial cells and Hassal’s corpuscles in the medulla of human thymus. Blood 1998; 91: 3323, [CSA]
   PubMed Web of Science ®Google Scholar
• Gerald G. New insights into the molecular mechanism of IL-10-mediated immunosuppression. J. Leukoc. Biol. 2005; 77: 3, [CSA]
   PubMed Web of Science ®Google Scholar
• Wynes M.W., Frankel S.K., Riches D.W. IL-4 induced macrophage derived IGF-I protects myofibroblasts from apoptosis following growth factor withdrawal. J. Leukoc. Biol. 2004; 76: 1019, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar