Effects of PCBs 52 and 77 on Th1/Th2 Balance in Mouse Thymocyte Cell Cultures

REFERENCES

• Mosmann T.R., Sad S. The expanding universe of T cell subsets-Th1, Th2 and more. Immunol. Today. 1996; 17: 138–146, [CSA]
   PubMedGoogle Scholar
• Sekimoto M., Tsuji T., Matsuzaki J., Chamoto K., Koda T., Nemoto K., Degawa M., Nishimura S., Nishimura T. Functional expression of the TrkC gene, encoding a high affinity receptor for NT-3, in antigen-specific T helper type 2 (Th2) cells. Immunol. Lett. 2003; 88: 221–226, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Nishimura T., Ohta A. A critical role for antigen-specific Th1 cells in acute liver injury in mice. J. Immunol. 1999; 162: 6503–6509, [CSA]
   PubMed Web of Science ®Google Scholar
• Apostoli P., Mangili A., Carasi S., Manno M. Relationship between PCBs in blood and D-glucaric acid in urine. Toxicol. Lett. 2003; 144: 17–26, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Carpenter D.O. Polychlorinated biphenyls and human health. Int. J. Occup. Med. Environ. Health. 1998; 11: 291–303, [CSA]
   PubMedGoogle Scholar
• De Vos S., Maervoet J., Schepens P., De Schrijver R. Polychlorinated biphenyls in broiler diets: their digestibility and incorporation in body tissues. Chemosphere 2003; 51: 7–11, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Finley B.L., Trowbridge K.R., Burton S., Proctor D.M., Panko J.M., Paustenbach D.J. Preliminary assessment of PCB risks to human and ecological health in the lower Passaic River. Toxicol. Environ. Health. 1997; 52: 95–118, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• van Larebeke N., Hens L., Schepens P., Covaci A., Baeyens J., Everaert K., Bernheim J.L., Vlietinck R., De Poorter G. The Belgian PCB and dioxin incident of January-June 1999: exposure data and potential impact on health. Environ. Health Perspect. 2001; 109: 265–273, [CSA]
   PubMed Web of Science ®Google Scholar
• Shin K.J., Bae S.S., Hwang Y.A., Seo J.K., Ryu S.H., Suh P.G. 2,2′,4,6,6′-Pentachlorobiphenyl induces apoptosis in human monocytic cells. Toxicol. Appl. Pharmacol. 2000; 169: 1–7, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Silkworth J.B., Antrim L., Kaminsky L.S. Correlations between polychlorinated biphenyl immunotoxicity, the aromatic hydrocarbon locus, and liver microsomal enzyme induction in C57BL/6 and DBA/2 mice. Toxicol. Appl. Pharm. 1984; 75: 156–165, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Cogliano V.C. Assessing the cancer risk from environmental PCBs. Environ. Health Persp. 1998; 106: 317–323, [CSA]
   PubMed Web of Science ®Google Scholar
• Chen Y.C., Yu M.L., Rogan W.J., Gladen B.C., Hsu C.C. A 6-year follow-up of behavior and activity disorders in Taiwan Yu-Cheng children. Am. J. Pub. Health. 1994; 84: 415–422, [CSA]
   PubMed Web of Science ®Google Scholar
• Rogan W.J., Gladen B.C. Neurotoxicology of PCBs and related compounds. Neurotoxicol. 1992; 13: 27–36, [CSA]
   PubMed Web of Science ®Google Scholar
• Safe S. Polychlorinated biphenyls (PCBs): Environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit. Rev. Toxicol. 1994; 24: 87–149, [CSA]
   PubMed Web of Science ®Google Scholar
• Harper N., Connor K., Steinberg M., Safe S. Immunosuppressive activity of polychlorinated biphenyl mixtures and congeners: nonadditive (antagonistic) interactions. Fund. Appl. Toxicol. 1995; 27: 131–139, [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Stack A.S., Altman-Hamamdzic S., Morris P.J., London S.D., London L. Polychlorinated biphenyl mixtures (Aroclors) inhibit LPS-induced murine splenocyte proliferation in vitro. Toxicology 1999; 139: 137–154, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Voie O.A., Wiik P., Fonnum F. Ortho-substituted polychlorinated biphenyls activate respiratory burst measured as luminol-amplified chemoluminescence in human granulocytes. Toxicol. Appl. Pharmacol. 1998; 150: 369–375, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Davis D., Safe S. Immunosuppressive activities of polychlorinated biphenyls in C57BL/6N mice: structure-activity relationships as Ah receptor agonists and partial antagonists. Toxicology 1990; 63: 97–111, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Gasiewicz T.A. Dioxins and the Ah receptor: probes to uncover processes in neuroendocrine development. NeuroToxicology 1997; 18: 393–414, [CSA]
   PubMed Web of Science ®Google Scholar
• Mackie D., Liu J., Loh Y-S., Thomas V. No evidence of dioxin cancer threshold. Environ. Health Perspect. 2003; 111: 1145–1147, [CSA]
   PubMed Web of Science ®Google Scholar
• Hansen L.G. The Ortho Side of PCBs: Occurrence and Disposition. Kluwer Academic Publishers, Boston 1999
   Google Scholar
• Oakley G.G., Roe A.L., Blouin R.A., Twaroski T.P., Ganguly T.C., Vore M., Lehmler H-J., Robertson L.W. 2,4,4′-Trichlorobiphenyl increases STAT5 transcriptional activity. Mol. Carcinog. 2001; 30: 199–208, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Denomme M.A., Bandiera S., Lambert I., Copp L., Safe L., Safe S. Polychlorinated biphenyls as phenobarbitone-type inducers of microsomal enzymes. Structure-activity relationships for a series of 2,4-dichloro-substituted congeners. Biochem. Pharmacol. 1983; 32: 2955–2963, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Harper N., Lowie L., Connor K., Kickerson R., Safe S. Immunosuppressive effects of highly chlorinated biphenyls and diphenyl ethers on T-cell dependent and independent antigens in mice. Toxicology 1993; 85: 123–135, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kerkvliet N.I., Steppan L.B., Smith B.B., Youngberg J.A., Henderson M.C., Buhler D.R. Role of the Ah locus in suppression of cytotoxic T lymphocyte activity by halogenated aromatic hydrocarbons (PCBs and TCDD): structure-activity relationships and effects in C57B1/6 mice congenic at the Ah locus. Fundam. Appl. Toxicol. 1990; 14: 532–541, [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Tan Y., Li D., Song R., Lawrence D., Carpenter D.O. Ortho-substituted PCBs kill thymocytes. Toxicol Sci. 2003; 76: 328–37, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Jeon Y.J., Youk E.S., Lee A.H., Suh J., Na Y.J., Kim H.M. Polychlorinated biphenyl-induced apoptosis of murine spleen cells is aryl hydrocarbon receptor independent but caspases dependent. Toxicol. Appl. Pharmacol. 2002; 181: 69–78, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Tan Y., Chen C.H., Lawrence D., Carpenter D.O. Ortho-substituted PCBs kill cells by altering membrane structure. Toxicol. Sci. 2004; 80: 54–59, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Segre M., Arena S.M., Greeley E.H., Melancon M.J., Graham D.A., French Jr,; J.B. Immunological and physiological effects of chronic exposure of Peromyscus leucopus to Aroclor 1254 at a concentration similar to that found at contaminated sites. Toxicology 2002; 174: 163–172, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Bernhoft A., Skaare J.U., Wiig O., Derocher A.E., Larsen H.J.S. Possible immunotoxic effects of organochlorines in Polar Bears (ursus maritimus) at Svalbard. J. Toxicol. Environ. Health. 2000; 59: 561–574, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Jepson P.D., Bennett P.M., Allchin C.R., Law R.J., Kuiken T., Baker J.R., Rogan E., Kirkwood J.K. Investigating potential associations between chronic exposure to polychlorinated biphenyls and infectious disease mortality in harbour porpoises from England and Wales. Sci. Total Environ. 1999; 243/244: 339–348, [CSA], [CROSSREF]
   Web of Science ®Google Scholar
• Weisglas-Kuperus N., Sas T.C.J., Koopman-Esseboom C., Van Der Zwan C.W., De Ridder M.A.J., Beishiuzen A., Hooijkaas H., Sauer P.J.J. Immunologic effects of background prenatal and postnatal exposure to dioxins and polychlorinated biphenyls in Dutch infants. Pediat. Res. 1995; 38: 404–410, [CSA]
   PubMed Web of Science ®Google Scholar
• Weisglas-Kuperus N., Vreugdenhil H.J.I., Mulder P.G.H. Immunological effects of environmental exposure to polychlorinated biphenyls and dioxins in Dutch school children. Toxicol. Lett. 2004; 149: 281–285, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Weisglas-Kuperus N., Patandin S., Berbers G.A.M., Sas T.C.J., Mulder P.G.H., Sauer P.J.J., Hooijkaas H. Immunologic effects of background exposure to polychlorinated biphenyls and dioxins in Dutch preschool children. Environ. Health Perspect. 2000; 108: 1203–1207, [CSA]
   PubMed Web of Science ®Google Scholar
• Van Den Heuvel R.L., Koopen G., Staessen J.A., Hond E.D., Verheyen G., Nawrot T.S., Roels H.A., Vlieetinck R., Schoeters G.E.R. Immunologic biomarkers in relation to exposure markers of PCBs and dioxins in Flemish adolescents (Belgium). Environ. Health Perspect. 2002; 110: 595–600, [CSA]
   PubMed Web of Science ®Google Scholar
• Oyama Y., Carpenter D.O., Ueno S., Hayashi H., Tomiyoshi F. Methylmercury induces Ca2+-dependent hyperpolarization of mouse thymocytes. A flow-cytometric study using fluorescent dyes. Eur. J. Pharmacol. 1995; 293: 101–107, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• McConkey D.J., Orrenius S. 2,3,7,8-tetrachlrorodibenzo-p-dioxin (TCDD) kills glucocorticoid-sensitive thymocytes in vivo. Biochem. Biophys. Res. Comm. 1989; 160: 1003–1008, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Doi H., Baba T., Tohyama C., Nohara K. Functional activation of arylhydrocarbon receptor (AhR) in primary T cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Chemosphere 2003; 52: 655–662, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Fisher M.T., Nagarkatti M., Nagarkatti P.S. Combined screening of thymocytes using apoptosis-specific cDNA array and promoter analysis yields novel gene targets mediating TCDD-induced toxicity. Toxicol. Sci. 2004; 78: 116–124, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kronenberg S., Lai Z., Esser C. Generation of alphabeta T-cell receptor+ CD4− CD8+ cells in major histocompatibility complex class I-deficient mice upon activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Immunology 2000; 100: 185–193, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Parslow T.G. Lymphocytes and lymphoid tissues. Medical Immunology, T.G. Parslow, D.P. Stites, A.I. Terr, J.B. Imboden. Lange Medical Books, New York 2001; 40–60
   Google Scholar
• Kerkvliet N.I. Immunological effects of chlorinated dibenzo-p-dioxins. Environ. Health Perspect. 1995; 103: 47–53, [CSA]
   PubMed Web of Science ®Google Scholar
• Nohara K., Ushio H., Tsukumo S., Kobayashi T., Kijima M., Tohyama C., Fujimaki H.;. Alterations of thymocyte development, thymic emigrants and peripheral T cell population in rats exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology 2000; 145: 227–235, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Esser C., Lai Z., Gleichmann E. Proliferation inhibition and CD4/CD8 thymocyte subset skewing by in vivo exposure of C57BL/6 mice to Ah receptor-binding 3,3′,4,4′-tetrachlorobiphenyl. Exp. Clin. Immunogenet. 1994; 11: 75–85, [CSA]
   PubMedGoogle Scholar
• Lai Z.W., Kremer J., Gleichmann E., Esser C. 3,3′,4,4′-Tetrachlorobiphenyl inhibits proliferation of immature thymocytes in fetal thymus organ culture. Scand. J. Immunol. 1994; 39: 480–488, [CSA]
   PubMed Web of Science ®Google Scholar
• Holsapple M.P., McCay J.A., Barnes D.W. Immunosuppression without liver induction by subchronic exposure to 2,7-dichlorodibenzo-p-dioxin in adult female B6C3F1 mice. Toxicol. Appl. Pharmacol. 1986; 83: 445–455, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Okey A.B., Riddick D.S., Harper P.A. The Ah receptor: mediator of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds. Toxicol. Lett. 1994; 70: 1–22, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Ganey P.E., Sirois J.E., Denison M., Robinson J.P., Roth R.A. Neutrophil function after exposure to polychlorinated biphenyls in vitro. Environ. Health Perspect. 1993; 101: 430–434, [CSA]
   PubMed Web of Science ®Google Scholar
• Brown A.P., Olivero-Verbel J., Holdan W.L., Ganey P.E. Neutrophil activation by polychlorinated biphenyls: structure-activity relationship. Toxicol. Sci. 1998; 46: 308–316, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Olivero J., Ganey P.E. Role of protein phosphorylation in activation of phospholipase A2 by the polychlorinated biphenyl mixture Aroclor 1242. Toxicol. Appl. Pharmacol. 2000; 163: 9–16, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Olivero J., Ganey P.E. Participation of Ca2+/calmodulin during activation of rat neutrophils by polychlorinated biphenyls. Biochem. Pharmacol. 2001; 62: 1125–1132, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sandal S., Yilmaz B., Chen C.H., Carpenter D.O. Comparative effects of technical toxaphene, 2,5-dichloro-3-biphenylol and octabromodiphenylether on cell viability, [Ca2+]i levels and membrane fluidity in mouse thymocytes. Toxicol. Lett. 2004; 151: 417–428, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Sargent L., Dragan Y.P., Erickson C., Laufer C.J., Pitot H.C. Study of the separate and combined effects of the non-planar 2,5,2′,5′- and the planar 3,4,3′,4′-tetrachlorobiphenyl in liver and lymphocytes in vivo. Carcinogenesis 1991; 12: 793–800, [CSA]
   PubMed Web of Science ®Google Scholar
• Ahne W., Jarre T. Environmental toxicology: polychlorinated biphenyls impair TNF-alpha release in vitro. J. Vet. Med. A Physiol. Pathol. Clin. Med. 2002; 49: 105–106, [CSA]
   PubMedGoogle Scholar
• Bilrha H., Roy R., Moreau B., Belles-Isles M., Dewailly E., Ayotte P. In vitro activation of cord blood mononuclear cells and cytokine production in a remote coastal population exposed to organochlorines and methyl mercury. Environ. Health Perspect. 2003; 111: 1952–1957, [CSA]
   PubMed Web of Science ®Google Scholar
• Rier S.E., Coe C.L., Lemieux A.M., Martin D.C., Morris R., Lucier G.W., Clark G.C. Increased tumor necrosis factor-alpha production by peripheral blood leukocytes from TCDD-exposed Rhesus monkeys. Toxicol. Sci. 2001; 60: 327–337, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Warren T.K., Mitchell K.A., Lawrence B.P. Exposure to 2,3,7,8-tetrachlrorodibenzo-p-dioxin suppresses the humoral and cell-mediated immune responses to influenza A virus without affecting cytolytic activity in the lung. Toxicol. Sci. 2000; 56: 114–123, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• De Vos S., Van Den Heuvel R., Hooghe R., Hooghe-Peters E.L. Limited effect of selected organic pollutants on cytokine production by peripheral blood leukocytes. Eur. Cytokine Netw. 2004; 15: 145–151, [CSA]
   PubMed Web of Science ®Google Scholar
• Daniel V., Huber W., Bauer K., Suesal C., Conradt C., Opelz G. Associations of blood levels of PCB, HCHs, and HCB with numbers of lymphocyte subpopulations, in vitro lymphocyte response, plasma cytokine levels and immunoglobulin autoantibodies. Environ. Health Perspect. 2001; 109: 173–178, [CSA]
   PubMed Web of Science ®Google Scholar
• Daniel V., Huber W., Bauer K., Suesal C., Conradt C., Opelz G. Associations of dichlorodiphenyltrichloroethane (DDT) 4.4 and dichlorodiphenyldichloroethylene (DDE) 4.4 blood levels with plasma IL-4. Arch. Environ. Health. 2002; 57: 541–547, [CSA]
   PubMed Web of Science ®Google Scholar