Wogonoside preserves against ischemia/reperfusion-induced myocardial injury by suppression of apoptosis, inflammation, and fibrosis via modulating Nrf2/HO-1 pathway

References

• Lu L, Liu M, Sun R, et al. Myocardial infarction: symptoms and treatments. Cell Biochem Biophys. 2015;72(3):865–867.
   PubMed Web of Science ®Google Scholar
• Ovize M, Kloner RA, Hale SL, et al. Coronary cyclic flow variations “precondition” ischemic myocardium. Circulation. 1992;85(2):779–789.
   PubMed Web of Science ®Google Scholar
• Yellon DM, Hausenloy DJ. Myocardial reperfusion injury. N Engl J Med. 2007;357(11):1121–1135.
   PubMed Web of Science ®Google Scholar
• Zhang J, Huang L, Shi X, et al. Metformin protects against myocardial ischemia-reperfusion injury and cell pyroptosis via AMPK/NLRP3 inflammasome pathway. Aging (Albany NY). 2020;12(23):24270–24287.
   PubMedGoogle Scholar
• McDonald H, Peart J, Kurniawan ND, et al. Hexarelin targets neuroinflammatory pathways to preserve cardiac morphology and function in a mouse model of myocardial ischemia-reperfusion. Biomed Pharmacother. 2020;127:110165.
   PubMed Web of Science ®Google Scholar
• Fan S, Zhang D, Liu F, et al. Artesunate alleviates myocardial ischemia/reperfusion-induced myocardial necrosis in rats and hypoxia/reoxygenation-induced apoptosis in H9C2 cells via regulating the FAK/PI3K/Akt pathway. Ann Transl Med. 2020;8(20):1291.
   PubMed Web of Science ®Google Scholar
• Jones SP, Tang XL, Guo Y, et al. The NHLBI-sponsored consortium for preclinicAl assESsment of cARdioprotective therapies (CAESAR): a new paradigm for rigorous, accurate, and reproducible evaluation of putative infarct-sparing interventions in mice, rabbits, and pigs. Circ Res. 2015;116(4):572–586.
   PubMed Web of Science ®Google Scholar
• Wang ZL, Wang S, Kuang Y, et al. A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of scutellaria baicalensis. Pharm Biol. 2018;56(1):465–484.
   PubMed Web of Science ®Google Scholar
• Wang Q, Wen R, Lin Q, et al. Wogonoside shows antifibrotic effects in an experimental regression model of hepatic fibrosis. Dig Dis Sci. 2015;60(11):3329–3339.
   PubMed Web of Science ®Google Scholar
• Wang CZ, Mehendale SR, Calway T, et al. Botanical flavonoids on coronary heart disease. Am J Chin Med. 2011;39(4):661–671.
   PubMed Web of Science ®Google Scholar
• Yu X, Chen D, Wang L, et al. Wogonoside inhibits inflammatory cytokine production in lipopolysaccharide-stimulated macrophage by suppressing the activation of the JNK/c-Jun signaling pathway. Ann Transl Med. 2020;8(8):532.
   PubMed Web of Science ®Google Scholar
• Jiang G, Chen D, Li W, et al. Effects of wogonoside on the inflammatory response and oxidative stress in mice with nonalcoholic fatty liver disease. Pharm Biol. 2020;58(1):1177–1183.
   PubMed Web of Science ®Google Scholar
• Cheng Y, Li S, Liu Y, et al. Treatment of brain edema by wogonoside is associated with inhibition of neuronal apoptosis and SIRT1 activation in rats. Med Sci Monit. 2020;26:e921250.
   PubMed Web of Science ®Google Scholar
• Li Y, Xu Z, Wang Q, et al. Protecting effect of wogonoside on ventricular remodeling in myocardial infarction rats by inhibiting the nuclear factor-kappa B (NF-κB) pathway. Lat Am J Pharm. 2017;36:172–178.
   Web of Science ®Google Scholar
• Gao YZ, Zhao LF, Ma J, et al. Protective mechanisms of wogonoside against lipopolysaccharide/D-galactosamine-induced acute liver injury in mice. Eur J Pharmacol. 2016;780:8–15.
   PubMed Web of Science ®Google Scholar
• Sinning C, Westermann D, Clemmensen P. Oxidative stress in ischemia and reperfusion: current concepts, novel ideas and future perspectives. Biomark Med. 2017;11(11):11031–11040.
   PubMed Web of Science ®Google Scholar
• Wu L, Xiong X, Wu X, et al. Targeting oxidative stress and inflammation to prevent ischemia-reperfusion injury. Front Mol Neurosci. 2020;13:28.
   PubMed Web of Science ®Google Scholar
• Shen Y, Liu X, Shi J, et al. Involvement of Nrf2 in myocardial ischemia and reperfusion injury. Int J Biol Macromol. 2019;125:496–502.
   PubMed Web of Science ®Google Scholar
• Hybertson BM, Gao B, Bose SK, et al. Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation. Mol Aspects Med. 2011;32(4–6):234–246.
   PubMed Web of Science ®Google Scholar
• Wu C, Chen RL, Wang Y, et al. Acacetin alleviates myocardial ischaemia/reperfusion injury by inhibiting oxidative stress and apoptosis via the Nrf-2/HO-1 pathway. Pharm Biol. 2022;60(1):553–561.
   PubMed Web of Science ®Google Scholar
• Liu K, Wang F, Wang S, et al. Mangiferin attenuates myocardial ischemia-reperfusion injury via MAPK/Nrf-2/HO-1/NF-κB in vitro and in vivo. Oxid Med Cell Longev. 2019;2019:7285434.
   PubMed Web of Science ®Google Scholar
• Moens AL, Claeys MJ, Timmermans JP, et al. Myocardial ischemia/reperfusion-injury, a clinical view on a complex pathophysiological process. Int J Cardiol. 2005;100(2):179–190.
   PubMed Web of Science ®Google Scholar
• Shen YF, Fan XQ. Advances in studies on pharmacological activities of wogonoside. J Shanghai Univ TCM. 2016;30(4):98–101.
   Google Scholar
• Xu M, Li X, Song L. Baicalin regulates macrophages polarization and alleviates myocardial ischaemia/reperfusion injury via inhibiting JAK/STAT pathway. Pharm Biol. 2020;58(1):655–663.
   PubMed Web of Science ®Google Scholar
• Liu X, Zhang S, Xu C, et al. The protective of baicalin on myocardial ischemia-reperfusion injury. Curr Pharm Biotechnol. 2020;21(13):1386–1393.
   PubMed Web of Science ®Google Scholar
• Chon H, Lee S, Yoon SY, et al. SERS-based competitive immunoassay of troponin I and CK-MB markers for early diagnosis of acute myocardial infarction. Chem Commun (Camb). 2014;50(9):1058–1060.
   PubMed Web of Science ®Google Scholar
• Gerhardt W, Ljungdahl L, Herbert AK. Troponin-T and CK MB (mass) in early diagnosis of ischemic myocardial injury. The helsingborg study, 1992. Clin Biochem. 1993;26(4):231–240.
   PubMed Web of Science ®Google Scholar
• Kini AS, Lee P, Marmur JD, et al. Correlation of postpercutaneous coronary intervention creatine kinase-MB and troponin I elevation in predicting mid-term mortality. Am J Cardiol. 2004;93(1):18–23.
   PubMed Web of Science ®Google Scholar
• Steven S, Frenis K, Oelze M, et al. Vascular inflammation and oxidative stress: major triggers for cardiovascular disease. Oxid Med Cell Longev. 2019;2019:7092151.
   PubMed Web of Science ®Google Scholar
• Hsu CP, Zhai P, Yamamoto T, et al. Silent information regulator 1 protects the heart from ischemia/reperfusion. Circulation. 2010;122(21):2170–2182.
   PubMed Web of Science ®Google Scholar
• Pu J, Yuan A, Shan P, et al. Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury. Eur Heart J. 2013;34(24):1834–1845.
   PubMed Web of Science ®Google Scholar
• Luan Y, Sun C, Wang J, et al. Baicalin attenuates myocardial ischemia-reperfusion injury through Akt/NF-κB pathway. J Cell Biochem. 2019;120(3):3212–3219.
   PubMed Web of Science ®Google Scholar
• Wallert M, Ziegler M, Wang X, et al. α-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury. Redox Biol. 2019;26:101292.
   PubMed Web of Science ®Google Scholar
• Cheng L, Jin Z, Zhao R, et al. Resveratrol attenuates inflammation and oxidative stress induced by myocardial ischemia-reperfusion injury: role of Nrf2/ARE pathway. Int J Clin Exp Med. 2015;8(7):10420–10428.
   PubMed Web of Science ®Google Scholar
• Yang YZ, Tang YZ, Liu YH. Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells. J Ethnopharmacol. 2013;148(1):271–276.
   PubMed Web of Science ®Google Scholar
• Anavi S, Tirosh O. iNOS as a metabolic enzyme under stress conditions. Free Radic Biol Med. 2020;146:16–35.
   PubMed Web of Science ®Google Scholar
• Loboda A, Damulewicz M, Pyza E, et al. Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism. Cell Mol Life Sci. 2016;73(17):3221–3247.
   PubMed Web of Science ®Google Scholar
• Jiang LJ, Zhang SM, Li CW, et al. Roles of the Nrf2/HO-1 pathway in the anti-oxidative stress response to ischemia-reperfusion brain injury in rats. Eur Rev Med Pharmacol Sci. 2017;21(7):1532–1540.
   PubMed Web of Science ®Google Scholar
• Qi B, Zhang X, Yu H, et al. Brazilin prevents against myocardial ischemia-reperfusion injury through the modulation of Nrf2 via the PKC signaling pathway. Ann Transl Med. 2021;9(4):312.
   PubMed Web of Science ®Google Scholar
• Cui L, Cao W, Xia Y, et al. Ulinastatin alleviates cerebral ischemia-reperfusion injury in rats by activating the Nrf-2/HO-1 signaling pathway. Ann Transl Med. 2020;8(18):1136.
   PubMed Web of Science ®Google Scholar