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Research Articles

IGF2BP3 aggravates lung adenocarcinoma progression by modulation of PI3K/AKT signaling pathway

, , ORCID Icon, , &
Pages 370-377 | Received 12 Aug 2022, Accepted 17 Nov 2022, Published online: 27 Mar 2023

References

  • Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics, 2021. CA A Cancer J Clin. 2021;71(1):7–33.
  • Feng R-M, Zong Y-N, Cao S-M, et al. Current cancer situation in China: good or bad news from the 2018 global cancer statistics? Cancer Commun. 2019;39(1):22.
  • Meza R, Meernik C, Jeon J, et al. Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010. PLoS One. 2015;10(3):e0121323.
  • Liu HY, Zhao H, Li WX. Integrated analysis of transcriptome and prognosis data identifies FGF22 as a prognostic marker of lung adenocarcinoma. Technol Cancer Res Treat. 2019;18:1533033819827317.
  • Gao N, Ye B. Circ-SOX4 drives the tumorigenesis and development of lung adenocarcinoma via sponging miR-1270 and modulating PLAGL2 to activate WNT signaling pathway. Cancer Cell Int. 2020;20:2.
  • Kolomeyer AM, Brucker AJ, O’Brien JM. Metastatic lung adenocarcinoma. Ophthalmology. 2017;124(7):969.
  • Feng D, Xu Y, Hu J, et al. A novel circular RNA, hsa-circ-0000211, promotes lung adenocarcinoma migration and invasion through sponging of hsa-miR-622 and modulating HIF1-α expression. Biochem Biophys Res Commun. 2020;521(2):395–401.
  • Saab J, Santos-Zabala ML, Loda M, et al. Fatty acid synthase and acetyl-CoA carboxylase are expressed in nodal metastatic melanoma but not in benign intracapsular nodal nevi. Am J Dermatopathol. 2018;40(4):259–264.
  • Bao G, Huang J, Pan W, et al. Long noncoding RNA CERS6-AS1 functions as a malignancy promoter in breast cancer by binding to IGF2BP3 to enhance the stability of CERS6 mRNA. Cancer Med. 2020;9(1):278–289.
  • Liu Y, Yu C, Wu Y, et al. CD44(+) fibroblasts increases breast cancer cell survival and drug resistance via IGF2BP3-CD44-IGF2 signalling. J Cell Mol Med. 2017;21(9):1979–1988.
  • Huang W, Li Y, Zhang C, et al. IGF2BP3 facilitates cell proliferation and tumorigenesis via modulation of JAK/STAT signalling pathway in human bladder cancer. J Cell Mol Med. 2020;24(23):13949–13960.
  • Hsu K-F, Shen M-R, Huang Y-F, et al. Overexpression of the RNA-binding proteins Lin28B and IGF2BP3 (IMP3) is associated with chemoresistance and poor disease outcome in ovarian cancer. Br J Cancer. 2015;113(3):414–424.
  • Guo W, Huai Q, Wan H, et al. Prognostic impact of IGF2BP3 expression in patients with surgically resected lung adenocarcinoma. DNA Cell Biol. 2021;40(2):316–331.
  • Zhu L, Yang N, Chen J, et al. LINC00052 upregulates EPB41L3 to inhibit migration and invasion of hepatocellular carcinoma by binding miR-452-5p. Oncotarget. 2017;8(38):63724–63737.
  • Wei R, Xiao Y, Song Y, et al. FAT4 regulates the EMT and autophagy in colorectal cancer cells in part via the PI3K-AKT signaling axis. J Exp Clin Cancer Res. 2019;38(1):112.
  • Tian Q, Wang L, Sun X, et al. Scopoletin exerts anticancer effects on human cervical cancer cell lines by triggering apoptosis, cell cycle arrest, inhibition of cell invasion and PI3K/AKT signalling pathway. J Buon. 2019;24(3):997–1002.
  • Pyo H, Yang M-S, Jou I, et al. Wortmannin enhances lipopolysaccharide-induced inducible nitric oxide synthase expression in microglia in the presence of astrocytes in rats. Neurosci Lett. 2003;346(3):141–144.
  • Fan S, Yan S, Yang Y, et al. Actin-like protein 8 promotes the progression of triple-negative breast cancer via activating PI3K/AKT/mTOR pathway. Onco Targets Ther. 2021;14:2463–2473.
  • Tang Y, Jiang Y, Qing C, et al. Systematic construction and validation of an epithelial-mesenchymal transition risk model to predict prognosis of lung adenocarcinoma. Aging. 2020;13(1):794–812.
  • Wang S-S, Fang Y-Y, Huang J-C, et al. Clinical value of microRNA-198-5p downregulation in lung adenocarcinoma and its potential pathways. Oncol Lett. 2019;18(3):2939–2954.
  • Zhao W, Lu D, Liu L, et al. Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) promotes lung tumorigenesis via attenuating p53 stability. Oncotarget. 2017;8(55):93672–93687.
  • Yu Y-Z, Lv D-J, Wang C, et al. Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR-653-5p. Mol Cancer. 2022;21(1):12.
  • Jin P, Huang Y, Zhu P, et al. CircRNA circHIPK3 serves as a prognostic marker to promote glioma progression by regulating miR-654/IGF2BP3 signaling. Biochem Biophys Res Commun. 2018;503(3):1570–1574.
  • Wu K, Wang X, Yu H, et al. LINC00460 facilitated tongue squamous cell carcinoma progression via the miR-320b/IGF2BP3 axis. Oral Dis. 2022;28(6):1496–1508.
  • Stewart DJ. Wnt signaling pathway in non-small cell lung cancer. J Natl Cancer Inst. 2014;106(1):djt356.
  • Gao F, Wang Q, Zhang C, et al. RNA methyltransferase METTL3 induces intrinsic resistance to gefitinib by combining with MET to regulate PI3K/AKT pathway in lung adenocarcinoma. J Cell Mol Med. 2021;25(5):2418–2425.
  • Liang J, Li H, Han J, et al. Mex3a interacts with LAMA2 to promote lung adenocarcinoma metastasis via PI3K/AKT pathway. Cell Death Dis. 2020;11(8):614.
  • Lei L, Wang Y, Li Z-H, et al. PHLDA3 promotes lung adenocarcinoma cell proliferation and invasion via activation of the wnt signaling pathway. Lab Invest. 2021;101(9):1130–1141.
  • Lu X-X, Cao L-Y, Chen X, et al. PTEN inhibits cell proliferation, promotes cell apoptosis, and induces cell cycle arrest via downregulating the PI3K/AKT/hTERT pathway in lung adenocarcinoma A549 cells. Biomed Res Int. 2016;2016:2476842.

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