Inhibition of Streptococcus mutans biofilm accumulation and development of dental caries in vivo by 7-epiclusianone and fluoride

References

• Ajdic , D , McShan , W M , McLaughlin , RE , Savic , G , Chang , J , Carson , M B , Primeaux , C , Tian , R , Kenton , S Jia , H . 2002 . Genome sequence of Streptococcus mutans ua159, a cariogenic dental pathogen . Proc Natl Acad Sci USA , 99 : 14434 – 14439 .
   PubMed Web of Science ®Google Scholar
• Almeida , L S , Murata , R M , Yatsuda , R , Dos Santos , M H , Nagem , T J , Alencar , S M , Koo , H and Rosalen , P L . 2008 . Antimicrobial activity of Rheedia brasiliensis and 7-epiclusianone against Streptococcus mutans . Phytomedicine , 15 : 886 – 891 .
   PubMed Web of Science ®Google Scholar
• Beighton , D . 2005 . The complex oral microflora of high-risk individuals and groups and its role in the caries process . Community Dent Oral , 33 : 248 – 255 .
   PubMed Web of Science ®Google Scholar
• Belli , W A , Buckley , D H and Marquis , R E . 1995 . Weak acid effects and fluoride inhibition of glycolysis by Streptococcus mutans GS-5 . Can J Microbiol , 41 : 785 – 791 .
   PubMed Web of Science ®Google Scholar
• Bowen , W H . 2002 . Do we need to be concerned about dental caries in the coming millennium? . Crit Rev Oral Biol Med , 13 : 126 – 131 .
   PubMedGoogle Scholar
• Bowen , W H , Madison , K M and Pearson , S K . 1988 . Influence of desalivation in rats on incidence of caries in intact cagemates . J Dent Res , 67 : 1316 – 1318 .
   PubMed Web of Science ®Google Scholar
• Brecx , M . 1997 . Strategies and agents in supragingival chemical plaque control . Periodontology , 15 : 100 – 108 .
   Web of Science ®Google Scholar
• Cegelski , L , Marshall , G R , Eldridge , G R and Hultgren , S J . 2008 . The biology and future prospects of antivirulence therapies . Nat Rev Microbiol , 6 : 17 – 27 .
   PubMed Web of Science ®Google Scholar
• Clarkson , J J and McLoughlin , J . 2000 . Role of fluoride in oral health promotion . Int Dent J , 50 : 119 – 128 .
   PubMed Web of Science ®Google Scholar
• DiPersio , J R , Mattingly , S J , Higgins , M L and Shockman , G D . 1974 . Measurement of intracellular iodophilic polysaccharide in two cariogenic strains of Streptococcus mutans by cytochemical and chemical methods . Infect Immun , 10 : 597 – 604 .
   PubMed Web of Science ®Google Scholar
• Duarte , S , Klein , M I , Aires , C P , Cury , J A , Bowen , W H and Koo , H . 2008 . Influences of starch and sucrose on Streptococcus mutans biofilms . Oral Microbiol Immunol , 23 : 206 – 212 .
   PubMedGoogle Scholar
• Dubois , M , Gilles , K A , Hamilton , J K , Rebers , P A and Smith , F . 1956 . Colorimetric method for determination of sugars and related substances . Anal Chem , 28 : 350 – 356 .
   Web of Science ®Google Scholar
• Dye , B A , Nowjack-Raymer , R , Barker , L K , Nunn , J H , Steele , J G , Tan , S , Lewis , B G and Beltran-Aguilar , E D . 2008 . Overview and quality assurance for the oral health component of the National Health and Nutrition Examination Survey (NHANES), 2003–04 . J Public Health Dent , 68 : 218 – 226 .
   PubMed Web of Science ®Google Scholar
• Featherstone , J D . 2006 . Caries prevention and reversal based on the caries balance . Pediatr Dent , 28 : 128 – 132 .
   PubMed Web of Science ®Google Scholar
• Koo , H . 2008 . Strategies to enhance the biological effects of fluoride on dental biofilms . Adv Dent Res , 20 : 17 – 21 .
   PubMedGoogle Scholar
• Koo , H and Jeon , J G . 2009 . Naturally occurring molecules as alternative therapeutic agents against cariogenic biofilms . Adv Dent Res , 21 : 63 – 68 .
   PubMedGoogle Scholar
• Koo , H , Sheng , J , Nguyen , P T and Marquis , R E . 2006 . Co-operative inhibition by fluoride and zinc of glucosyltransferase production and polysaccharide synthesis by mutans streptococci in suspension cultures and biofilms . FEMS Microbiol Lett , 254 : 134 – 140 .
   PubMed Web of Science ®Google Scholar
• Koo , H , Xiao , J , Klein , M I and Jeon , J G . 2010 . Exopolysaccharides produced by Streptococcus mutans glucosyltransferases modulate the establishment of microcolonies within multispecies biofilms . J Bacteriol , 192 : 3024 – 3032 .
   PubMed Web of Science ®Google Scholar
• Koo , H , Rosalen , P L , Cury , J A , Park , Y K , Ikegaki , M and Sattler , A . 1999 . Effect of Apis mellifera propolis from two Brazilian regions on caries development in desalivated rats . Caries Res , 33 : 393 – 400 .
   PubMed Web of Science ®Google Scholar
• Koo , H , Hayacibara , M F , Schobel , B D , Cury , J A , Rosalen , P L , Park , Y K , Vacca-Smith , A M and Bowen , W H . 2003 . Inhibition of Streptococcus mutans biofilm accumulation and polysaccharide production by apigenin and tt-farnesol . J Antimicrob Chemother , 52 : 782 – 789 .
   PubMed Web of Science ®Google Scholar
• Koo , H , Schobel , B , Scott-Anne , K , Watson , G , Bowen , W H , Cury , J A , Rosalen , P L and Park , Y K . 2005 . Apigenin and tt-farnesol with fluoride effects on S. mutans biofilms and dental caries . J Dent Res , 84 : 1016 – 1020 .
   PubMed Web of Science ®Google Scholar
• Koo , H , Pearson , S K , Scott-Anne , K , Abranches , J , Cury , J A , Rosalen , P L , Park , Y K , Marquis , R E and Bowen , W H . 2002 . Effects of apigenin and tt-farnesol on glucosyltransferase activity, biofilm viability and caries development in rats . Oral Microbiol Immunol , 17 : 337 – 343 .
   PubMedGoogle Scholar
• Larson , R M . Merits and modifications of scoring rat dental caries by Keyes' method . Animal models in cariology. Microbial Abstracts (Special Suppl) . Edited by: Tanzer , JM. pp. 195 – 203 . Washington : IRL Press .
   Google Scholar
• Lillie , R D . 1965 . Histopathologic technic and practical histochemistry , New York : Blakiston Division .
   Google Scholar
• Loesche , W J . 1986 . Role of Streptococcus mutans in human dental decay . Microbiol Rev , 50 : 353 – 380 .
   PubMedGoogle Scholar
• Marquis , R E , Clock , S A and Mota-Meira , M . 2003 . Fluoride and organic weak acids as modulators of microbial physiology . FEMS Microbiol Rev , 26 : 493 – 510 .
   PubMed Web of Science ®Google Scholar
• Marsh , P D . 2003 . Are dental diseases examples of ecological catastrophes? . Microbiology , 149 : 279 – 294 .
   PubMed Web of Science ®Google Scholar
• Murata , R M , Branco de Almeida , L S , Yatsuda , R , Dos Santos , M H , Nagem , T J , Rosalen , P L and Koo , H . 2008 . Inhibitory effects of 7-epiclusianone on glucan synthesis, acidogenicity and biofilm formation by Streptococcus mutans . FEMS Microbiol Lett , 282 : 174 – 181 .
   PubMed Web of Science ®Google Scholar
• Murata , R M , Yatsuda , R , Dos Santos , M H , Kohn , L K , Martins , F T , Nagem , T J , Alencar , S M , de Carvalho , J E and Rosalen , P L . 2010 . Antiproliferative effect of benzophenones and their influence on cathepsin activity . Phytother Res , 24 : 379 – 383 .
   PubMed Web of Science ®Google Scholar
• Newman , D J . 2008 . Natural products as leads to potential drugs: an old process or the new hope for drug discovery? . J Med Chem , 51 : 2589 – 2599 .
   PubMed Web of Science ®Google Scholar
• NIH . 2001 . Diagnosis and management of dental caries throughout life. National Institutes of Health Consensus Development Conference statement, March 26–28, 2001 . J Dent Educ , 65 : 1162 – 1168 .
   PubMedGoogle Scholar
• Paes Leme , A F , Koo , H , Bellato , C M , Bedi , G and Cury , J A . 2006 . The role of sucrose in cariogenic dental biofilm formation-new insight . J Dent Res , 85 : 878 – 887 .
   PubMed Web of Science ®Google Scholar
• Petersen , P E , Bourgeois , D , Ogawa , H , Estupinan-Day , S and Ndiaye , C . 2005 . The global burden of oral diseases and risks to oral health . Bull World Health Organ , 83 : 661 – 669 .
   PubMed Web of Science ®Google Scholar
• Santos , M H , Nagem , T J , de Oliveira , T T and Braz , R . 1999 . 7-epiclusianone, the new tetraprenylated benzophenone and others chemical constituents from the fruits of Rheedia gardneriana . Quim Nova , 22 : 654 – 660 .
   Web of Science ®Google Scholar
• SAS Institute . 1990 . SAS/STAT user's guide. Version 6 , 4th ed , Cary , NC : SAS Institute .
   Google Scholar
• Schilling , K M and Bowen , W H . 1988 . The activity of glucosyltransferase adsorbed onto saliva-coated hydroxyapatite . J Dent Res , 67 : 2 – 8 .
   PubMed Web of Science ®Google Scholar
• Schilling , K M and Bowen , W H . 1992 . Glucans synthesized in situ in experimental salivary pellicle function as specific binding sites for Streptococcus mutans . Infect Immun , 60 : 284 – 295 .
   PubMed Web of Science ®Google Scholar
• Spatafora , G , Rohrer , K , Barnard , D and Michalek , S . 1995 . A Streptococcus mutans mutant that synthesizes elevated levels of intracellular polysaccharide is hypercariogenic in vivo . Infect Immun , 63 : 2556 – 2563 .
   PubMed Web of Science ®Google Scholar
• Tanzer , J M , Freedman , M L , Woodiel , F N , Eifert , R L and Rinehimer , L A . Association of Streptococcus mutans virulence with synthesis of intracellular polysaccharide . Proceedings, Microbiological Aspects of Dental Caries. Special Suppl, Microbiology Abstracts . Edited by: Stiles , H M , Loesche , W J and O'Brien , T L . Vol. 3 , pp. 596 – 616 . London , , UK : Information Retrieval, Inc .
   Google Scholar
• ten Cate , J M . 1999 . Current concepts on the theories of the mechanism of action of fluoride . Acta Odontol Scand , 57 : 325 – 329 .
   PubMed Web of Science ®Google Scholar
• Vacca-Smith , A M and Bowen , W H . 1998 . Binding properties of streptococcal glucosyltransferases for hydroxyapatite, saliva-coated hydroxyapatite, and bacterial surfaces . Arch Oral Biol , 43 : 103 – 110 .
   PubMed Web of Science ®Google Scholar
• Xiao , J and Koo , H. 2010 . Structural organization and dynamics of exopolysaccharide matrix and microcolonies formation by Streptococcus mutans in biofilms . J Appl Microbiol , 108 : 2103 – 2113 .
   PubMed Web of Science ®Google Scholar
• Yamashita , Y , Bowen , W H , Burne , R A and Kuramitsu , H K . 1993 . Role of the Streptococcus mutans gtf genes in caries induction in the specific-pathogen-free rat model . Infect Immun , 61 : 3811 – 3817 .
   PubMed Web of Science ®Google Scholar
• Zero , D T . 2006 . Dentifrices, mouthwashes, and remineralization/caries arrestment strategies . BMC Oral Health , 6 Suppl 1 : S9
   PubMedGoogle Scholar