Comparison of Two Different Fixation Techniques for a Segmental Defect in a Rat Femur Model

REFERENCES

• Adah F, Benghuzzi H, Tucci M, Russell G, England B. Effects of sustained release of statin by means of tricalcium phosphate lysine delivery system in defect and segmental femoral injuries on certain biochemical markers in vivo. Biomed Sci Instrum. 2006; 42: 126–135
   PubMedGoogle Scholar
• Kirui P K, Cameron J, Benghuzzi H A, Tucci M, Patel R, Adah F, Russell G. Effects of sustained delivery of thymoqiunone on bone healing of male rats. Biomed Sci Instrum 2004; 40: 111–116
   PubMedGoogle Scholar
• Johnson K D, August A, Sciadini M F, Smith C. Evaluation of ground cortical autograft as a bone graft material in a new canine bilateral segmental long bone defect model. J Orthop Trauma 1996; 10: 28–36
   PubMed Web of Science ®Google Scholar
• Srouji S, Blumenfeld I, Rachmiel A, Livne E. Bone defect repair in rat tibia by TGF-beta1 and IGF-1 released from hydrogel scaffold. Cell Tissue Bank 2004; 5: 223–230
   PubMedGoogle Scholar
• Sciadini M F, Dawson J M, Johnson K D. Bovine-derived bone protein as a bone graft substitute in a canine segmental defect model. J Orthop Trauma 1997; 11: 496–508
   PubMed Web of Science ®Google Scholar
• Tiedeman J J, Connolly J F, Strates B S, Lippiello L. Treatment of nonunion by percutaneous injection of bone marrow and demineralized bone matrix. An experimental study in dogs. Clin Orthop Relat Res. 1991; 268: 294–302
   Google Scholar
• Einhorn T A, Lane J M, Burstein A H, Kopman C R, Vigorita V J. The healing of segmental bone defects induced by demineralized bone matrix. A radiographic and biomechanical study. J Bone Joint Surg Am 1984; 66: 274–279
   PubMed Web of Science ®Google Scholar
• Jager M, Sager M, Lensing-Hohn S, Krauspe R. The critical size bony defect in a small animal for bone healing studies (II): Implant evolution and surgical technique on a rat's femur. Biomed Tech (Berl) 2005; 50: 137–142
   PubMed Web of Science ®Google Scholar
• Tuominen T, Jamsa T, Oksanen J, Tuukkanen T, Gao T J, Lindholm T S, Jalovaara P. Composite implant composed of hydroxyapatite and bone morphogenetic protein in the healing of a canine ulnar defect. Ann Chir Gynaecol 2001; 90: 32–36
   PubMedGoogle Scholar
• Tuominen T, Jamsa T, Tuukkanen J, Nieminen P, Lindholm T C, Lindholm T S, Jalovaara P. Native bovine bone morphogenetic protein improves the potential of biocoral to heal segmental canine ulnar defects. Int Orthop 2000; 24: 289–294
   PubMed Web of Science ®Google Scholar
• Kitsugi T, Yamamuro T, Kokubo T. Bonding behavior of a glass-ceramic containing apatite and wollastonite in segmental replacement of the rabbit tibia under load-bearing conditions. J Bone Joint Surg Am 1989; 71: 264–272
   PubMed Web of Science ®Google Scholar
• Kokubu T, Hak D J, Hazelwood S J, Reddi A H. Development of an atrophic nonunion model and comparison to a closed healing fracture in rat femur,. J Orthop Res 2003; 21: 503–510
   PubMed Web of Science ®Google Scholar
• Chu T M, Sargent P, Warden S J, Turner C H, Stewart R L. Preliminary evaluation of a load-bearing BMP-2 carrier for segmental defect regeneration. Biomed Sci Instrum 2006; 42: 42–47
   PubMedGoogle Scholar
• Conflitti J, Graves M, Russell G, Tucci M, Benghuzzi H. Plating of rat femoral shaft osteotomies: Report of a technique and preliminary results. Biomed Sci Instrum 2003; 39: 278–283
   PubMedGoogle Scholar
• Chen X, Kidder L S, Lew W D. Osteogenic protein-1 induced bone formation in an infected segmental defect in the rat femur. J Orthop Res 2002; 20: 142–150
   PubMed Web of Science ®Google Scholar
• Concannon M J, Boschert M T, Puckett C L. Bone induction using demineralized bone in the rabbit femur: A long-term study. Plast Reconstr Surg 1997; 99: 1983–1988
   PubMed Web of Science ®Google Scholar
• Gerhart T N, Kirker-Head C A, Kriz M J, Holtrop M E, Hennig G E, Hipp J, Schelling S H, Wang E. Healing segmental femoral defects in sheep using recombinant human bone morphogenetic protein. Clin Orthop Relat Res. 1993; 293: 317–323
   PubMedGoogle Scholar
• Hunt T R, Schwappach J R, Anderson H C. Healing of a segmental defect in the rat femur with use of an extract from a cultured human osteosarcoma cell-line (Saos-2). A preliminary report. J Bone Joint Surg Am 1996; 78: 41–48
   PubMed Web of Science ®Google Scholar
• Viateau V, Guillemin G, Yang Y C, Bensaid W, Reviron T, Oudina K, Meunier A, Sedel L, Petite H. A technique for creating critical-size defects in the metatarsus of sheep for use in investigation of healing of long-bone defects. Am J Vet Res. 2004; 65: 1653–1657
   PubMed Web of Science ®Google Scholar
• Cullinane D M, Fredrick A, Eisenberg S R, Pacicca D, Elman M V, Lee C, Salisbury K, Gerstenfeld L C, Einhorn T A. Induction of a neoarthrosis by precisely controlled motion in an experimental mid-femoral defect. J Orthop Res 2002; 20: 579–586
   PubMed Web of Science ®Google Scholar
• Grundnes O, Reikeras O. Mechanical effects of function on bone healing. Nonweight bearing and exercise in osteotomized rats. Acta Orthop Scand 1991; 62: 163–165
   PubMed Web of Science ®Google Scholar
• Probst A, Jansen H, Ladas A, Spiegel H U. Callus formation and fixation rigidity: A fracture model in rats. J Orthop Res. 1999; 17: 256–260
   PubMed Web of Science ®Google Scholar
• Reikeras O. Healing of osteotomies under different degrees of stability in rats. J Orthop Trauma, 4: 175–178
   PubMedGoogle Scholar
• Ryhanen J, Kallioinen M, Serlo W, Peramaki P, Junila J, Sandvik P, Niemela E, Tuukkanen J. Bone healing and mineralization, implant corrosion, and trace metals after nickel–titanium shape memory metal intramedullary fixation. J Biomed Mater Res 1999; 47: 472–480
   PubMed Web of Science ®Google Scholar
• Viljanen J, Pihlajamaki H, Majola A, Tormala P, Rokkanen P. Absorbable polylactide pins versus metallic Kirschner wires in the fixation of cancellous bone osteotomies in rats. Ann Chir Gynaecol. 1997; 86: 66–73
   PubMedGoogle Scholar