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Journal of Investigative Surgery Volume 32, 2019 - Issue 6
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Original Research

The Effects of Local and Systemic Administration of Proline on Wound Healing in Rats

Husnu AydinDepartment of General Surgery, Erciyes University, Istanbul, TurkeyCorrespondence[email protected]
, MD,
Cihad TatarDepartment of General Surgery, Istanbul Training and Research Hospital, Istanbul, Turkey
, MD,
Osman Anil SavasDepartment of General Surgery, Altinbas University, Istanbul, Turkey
, MD,
Tamer KarsidagDepartment of General Surgery, Acibadem University, Istanbul, Turkey
(Associate Professor) ,
Bahri OzerDepartment of General Surgery, Abant Izzet Baysal University, Bolu, Turkey
, MD,
Nevra DursunDepartment of Pathology, Istanbul Training and Research Hospital, Istanbul, Turkey
, MD,
Aylin BekemDepartment of Metallurgical and Materials Engineering, Yildiz Technical University, Istanbul, Turkey
(Research Assistant) ,
Ahmet UnalDepartment of Metallurgical and Materials Engineering, Yildiz Technical University, Istanbul, Turkey
(Professor) &
Ishak Sefa TuzunDepartment of General Surgery, Istanbul Training and Research Hospital, Istanbul, Turkey
(Professor) show all
Pages 523-529 | Received 23 Nov 2017, Accepted 12 Feb 2018, Published online: 01 Mar 2018

REFERENCES

  • Hu CA, Khalil S, Zhaorigetu S. Human D1-pyrroline-5- carboxylate synthase: function and regulation. Amino Acids. 2008;35:665–672. doi:10.1007/s00726-008-0075-0. PMID: 18401542.
  • Guoyao WU, Bazer Fuller W, Burghardt Robert C. Proline and hydroxyproline metabolism: implications for animal and human nutrition. Amino Acids. 2010; 40:1053–1063. doi:10.1007/s00726-010-0715-z. PMID: 20697752.
  • Karsıdag T, Assensio J, Kabukcuoglu F. Preliminary study comparing the effects of locally and systemically applied L-carnitine on the healing of full-thickness skin defects. Scand J Surg. 2010;99:147–152. doi:10.1177/145749691009900309. PMID: 21044932.
  • Ponrasu T, Jamuna S, Mathew A. Efficacy of L-proline administration on the early responses during cutaneous wound healing in rats. Amino Acids. 2013 45:179–189. doi:10.1007/s00726-013-1486-0. PMID: 23508578.
  • Williams JZ, Barbul A. Nutrition and wound healing. Surg Clin North Am. 2003;83:571–574. doi:10.1016/S0039-6109(02)00193-7. PMID: 12822727.
  • Baker DH. Advances in protein-amino acid nutrition of poultry. Amino Acids. 2009; 37:29–41. doi:10.1007/s00726-008-0198-3. PMID: 19009229.
  • Barbul A. Proline precursors to sustain Mammalian collagen synthesis. J Nutr. 2008; 138:2021–2024. doi:10.1093/jn/138.10.2021S.
  • Elango R, Ball RO, Pencharz PB. Amino acid requirements in humans: with a special emphasis on the metabolic availability of amino acids. Amino Acids. 2009;37:19–27. doi:10.1007/s00726-009-0234-y. PMID: 19156481.
  • Wu G, Bazer FW, Datta S. Proline metabolism in the conceptus: Implications for fetal growth and development. Amino Acids. 2008;35:691–702. doi:10.1007/s00726-008-0052-7. PMID: 18330497.
  • Townsend CM, Beauchamp DR, Evers MB. Sabiston textbook of surgery: the biological basis of modern surgical practice. 17th ed. Philadelphia: Elsevier Saunders; 2004.
  • Ponrasu T, Suguna L. Efficacy of Annona Squamosa on wound healing in streptozotocin induced diabetic rats. Int Wound J. 2012;9:613–623 doi:10.1111/j.1742-481X.2011.00924.x. PMID: 22233431.
  • Ashcroft GS, Mills SJ. Androgen receptor-mediated inhibition of cutaneous wound healing. J Clin Invest. 2002;110:615–624. doi:10.1172/JCI0215704. PMID: 12208862.
  • Ashcroft GS, Mills SJ, Ashworth JJ. Ageing and wound healing. Biogerontology. 2002;3:337–345. doi:10.1023/A:1021399228395. PMID: 12510172.
  • Gilliver SC, Ruckshanthi JP, Atkinson SJ. Androgens influence expression of matrix proteins and proteolytic factors during cutaneous wound healing. Lab Invest. 2007;87:871–881. doi:10.1038/labinvest.3700627. PMID: 17607299.
  • Barbul A, Efron DT, Kavalukas SL. Schwartz Principles of Surgery. In: Brunicardi FC editör. Wound Healing. New York, USA: Mc Graw Hill; 2015. p. 241–273.
  • Wu G, Bazer FW, Burghardt RC. Impacts of amino acid nutrition on pregnancy outcome in pigs: mechanisms and implications for swine production. J Anim Sci. 2010;88:195–204. doi:10.2527/jas.2009-2446.
  • Tatar C, Aydin H, Karsidag T, et al. The effects of platelet-rich plasma on wound healing in rats. Int J Clin Exp Med. 2017;10:7698–7706.
  • Trent JT, Kirsner RS. Leg ulcers secondary to prolidase deficiency. Adv Skin Wound Care. 2004;17:468–472 doi:10.1097/00129334-200411000-00011. PMID: 15632738.
  • Özcan Ö, Gültepe M, İpçioğlu OM. Prolidazın Mutlak Aktivitesini Değerlendirmede Fotometrik Enzim Aktivitesi Ölçüm Metodunun Optimizasyonu. Turk J Biochem. 2007;32;12–16.
  • Dunphy JE, Udupa KN. Chemical and histochemical sequences in the normal healing of wounds. N Engl J Med. 1955;253:847–851. doi:10.1056/NEJM195511172532002. PMID: 13272801.

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