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Journal of Investigative Surgery Volume 32, 2019 - Issue 8
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Original Research

Allium Sativum Methanolic Extract (garlic) Improves Therapeutic Efficacy of Albendazole Against Hydatid Cyst: In Vivo Study

K H Haji MohammadiDepartment of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, IranView further author information
,
M HeidarpourDepartment of Clinical Sciences, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, IranView further author information
&
H BorjiDepartment of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, IranCorrespondence[email protected]
View further author information
Pages 723-730 | Received 07 Jan 2018, Accepted 28 Mar 2018, Published online: 25 Apr 2018

REFERENCES

  • Eckert J, Deplazes P. Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern. Clin Microbiol Rev. 2004;17:107–35. doi:10.1128/CMR.17.1.107-135.2004. PMID:14726458.
  • Moro P, Schantz PM. Echinococcosis: a review. Int J Infect Dis. 2009;13:125–33. doi:10.1016/j.ijid.2008.03.037. PMID:18938096.
  • Caremani M R, Maestrini U, Occhini S, Sassoli A, Accorsi A, Giorgio C. Echographic epidemiology of cystic hydatid disease in Italy. Eur J Epidemiol. 1993;9:401–404. doi:10.1007/BF00157397. PMID:8243595.
  • El-On J. Benzimidazole treatment of cystic echinococcosis. Acta Tropic. 2003;85:243–52. doi:10.1016/S0001-706X(02)00217-6.
  • Teggi A, Lastilla MG, De Rosa F. Therapy of human hydatid disease with mebendazole and albendazole. Antimicrob Agents Chemother. 1993;37:1679–84. doi:10.1128/AAC.37.8.1679. PMID:8215283.
  • Anand LCS, Rajagopalan BS, Mohan SLR. Management of liver hydatid cysts: current perspectives. Med. J. Armed Forces India. 2012;68:304–309. doi:10.1016/j.mjafi.2012.04.010. PMID:24532894.
  • Anthony JP, Fyfe L, Smith H. Plant active components – a resource for antiparasitic agents? Trends Parasitol. 2005;21:462–8. doi:10.1016/j.pt.2005.08.004. PMID:16099722.
  • Goncagul G, Ayaz E. Antimicrobial effect of garlic (Allium sativum). Recent Pat Anti Infect Drug Discov. 2010;5:91–3. doi:10.2174/157489110790112536.
  • Nicastro HL, Ross S, Milner JA. Garlic and onions: Their cancer prevention properties. Cancer Prev Res (Phila). 2015;8(3):181–189. doi:10.1158/1940-6207.CAPR-14-0172. PMID:25586902.
  • Moazeni M, Nazer A. In vitro Effectiveness of Garlic (Allium sativum) extract on scolices of hydatid cyst. World J Surg. 2010;34:2677–81. doi:10.1007/s00268-010-0718-7. PMID:20625727.
  • Hashemi Tabar GR, Razmi GR, Maleki M. In vivo effect of albendazole and mebendazole on hydatid cyst of mice. Archives Razi Institute. 2009;64(1):45–50.
  • Amagase H. Clarifying the real bioactive constituents of garlic. J Nutr. 2006;136:716S–25S. doi:10.1093/jn/136.3.716S. PMID:16484550.
  • Reuter HD, Koch HP, Lawson LD. Therapeutic effects and applications of garlic and its preparations. In Koch HP, Lawson LD (ed.), Garlic: the science and therapeutic application of Allium sativum L. and related species. Baltimore, Md: Williams and Wilkins; 1996:135–213.
  • Rabinkov A, Miron T, Konstantinovski L. The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins. Biochim Biophys Acta. 1998;1379:233–44. doi:10.1016/S0304-4165(97)00104-9. PMID:9528659.
  • Ankri S, Miron T, Rabinkov A. Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica. Antimicrob Agents Chemother. 1997;41:2286–8. PMID:9333064.
  • Kyo E, Uda N, Kasuga S. Immunomodulatory effects of aged garlic extract. J Nutr. 2001;131:1075S–9S. doi:10.1093/jn/131.3.1075S. PMID:11238820.
  • Ghazanfari T, Hassan ZM, Ebtekar M, Ahamdiani A, Naderi G, Azar. Garlic induces a shift in cytokine pattern in Leishmania major infected Balb/c mice. Scand. J Immunol. 2000;52:491–496.
  • Siracusano A, Delunardo F, Teggi A, Ortona E. Cystic echinococcosis: aspects of immune response, immunopathogenesis and immune evasion from the human host. Disord Drug Targets. 2012;12(1):16–23.
  • Hikino H, Tohkin M, Kiso Y, Namiki T, Nishimura S, Takeyama K. Antihepatotoxic actions of Allium sativum bulbs. Planta Medica. 1986;52(3):163–68. doi:10.1055/s-2007-969111. PMID:3749336.
  • Dkhila MA, Abdel-Bakia AC, Wunderlicha F. Anticoccidial and anti inflammatory activity of garlic in murine Eimeria papillata infections. Vet Parasitol. 2006;175:66–72. doi:10.1016/j.vetpar.2010.09.009.
  • Gedik N, Kabasakal L, Sehirli O. Long-term administration of aqueous garlic extract (AGE) alleviates liver fibrosis and oxidative damage induced by biliary obstruction in rats. Life Sci. 2005;76:2593–2606. doi:10.1016/j.lfs.2004.11.021. PMID:15769483.
  • Chung LY. The antioxidant properties of garlic compounds: allylcysteine, alliin, allicin, and allyl disulfide. J Med Food. 2006;9:205–13. doi:10.1089/jmf.2006.9.205. PMID:16822206.
  • Chang HP, Chen YH. Differential effects of organosulfur compounds from garlic oil on nitric oxide and prostaglandin E2 in stimulated macrophages. Nutrition. 2005;21:530–6. doi:10.1016/j.nut.2004.07.018. PMID:15811776.

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