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Original Research

Protective Effects of Betanin against Oxidative Stress in a Peripheral Artery Vasospasm Model in Rat

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References

  • Guzik TJ, Touyz RM. Oxidative stress, inflammation, and vascular aging in hypertension. Hypertension 2017;70(4):660–667. doi:10.1161/HYPERTENSIONAHA.117.07802.
  • Satoh M, Date I, Nakajima M, et al. Inhibition of poly(ADP-ribose) polymerase attenuates cerebral vasospasm after subarachnoid hemorrhage in rabbits. Stroke 2001;32(1):225–231.
  • Han J, Tan C, Wang Y, Yang S, Tan D. Betanin reduces the accumulation and cross-links of collagen in high-fructose-fed rat heart through inhibiting non-enzymatic glycation. Chem Biol Interact. 2015;227:37–44. doi:10.1016/j.cbi.2014.12.032.
  • Zou DM, Brewer M, Garcia F, Feugang JM, et al. Cactus pear: a natural product in cancer chemoprevention. Nutr J. 2005;4:25. 10.1186/1475-2891-4-25.
  • Vincent KR, Scholz R. Separation and quantification of red beet betacyanins and betaxanthins by high performance liquid chromatography. J Agric Food Chem. 1978;26(4):812–816. doi:10.1021/jf60218a026.
  • Sakihama Y, Maeda M, Hashimoto M, Tahara S, Hashidoko Y. Beetroot betalain inhibits peroxynitrite-mediated tyrosine nitration and DNA strand cleavage. Free Radic Res. 2012;46(1):93–99. doi:10.3109/10715762.2011.641157.
  • Azeredo HMC. Betalains: properties, sources, applications, and stability-a review. Int J Food Sci Tech. 2009;44(12):2365–2376. doi:10.1111/j.1365-2621.2007.01668.x.
  • Tesoriere L, Butera D, Allegra M, Fazzari M, Livrea MA. Distribution of betalain pigments in red blood cells after con- sumption of cactus pear fruits and increased resistance of the cells to ex vivo induced oxidative hemolysis in humans. J Agr Food Chem 2005;53(4):1266–1270. doi:10.1021/jf048134+.
  • Gaweł S, Wardas M, Niedworok E, Wardas P. Malondialdehyde (MDA) as a lipid peroxidation marker. Wiad Lek 2004;57(9):453–455.
  • Marletta MA. Nitric oxide synthase structure and mechanism. J Biol Chem. 1993;268(17):12231–12234.
  • Small HY, Migliarino S, Czesnikiewicz-Guzik M, Guzik TJ. Hypertension: focus on autoimmunity and oxidative stress. Free Radic Biol Med. 2018;125:104–115. doi:10.1016/j.freeradbiomed.2018.05.085.
  • Khan M, Sharma S. Physiology, pulmonary vasoconstriction. Statpearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018.
  • Atakisi E, Merhan O. Nitric oxide synthase and nitric oxide involvement in different toxicities. In: Seyed Soheil Saeedi Saravi (ed). Nitric Oxide Synthase - Simple Enzyme-Complex Roles, InTech. 2017;197–214. doi:10.5772/intechopen.68494.
  • Okada T, Harada T, Bark DH, Mayberg MR. A rat femoral artery model for vasospasm. Neurosurgery 1990;27(3):349–356.
  • Han J, Zhang Z, Yang S, Wang J, Yang X, Tan D. Betanin attenuates paraquat-induced liver toxicity through a mitochondrial pathway. Food Chem Toxicol. 2014;70:100–106. doi:10.1016/j.fct.2014.04.038.
  • Yoshioka T, Kawada K, Shimada T, Mori M. Lipid peroxidation in maternal and cord blood and protective mechanism against activated-oxygen toxicity in the blood. Am J Obstet Gynecol. 1979;135(3):372–376. doi:10.1016/0002-9378(79)90708-7.
  • Miranda KM, Espey MG, Wink DA. A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide. 2001;5(1):62–71. doi:10.1006/niox.2000.0319.
  • Koike T, Tamura S, Yu Y, Kuniyoshi N, Shiomi M. High susceptibility of atherosclerotic coronary arteries to the onset of vasospasm and angina pectoris-like symptoms due to coronary spasm in WHHLMI rabbits. Exp Anim. 2016;65(4):419–426. doi:10.1538/expanim.16-0035.
  • Krahn AD, Healey JS, Chauhan V, et al. Systematic assessment of patients with unexplained cardiac arrest: Cardiac Arrest Survivors With Preserved Ejection Fraction Registry (CASPER). Circulation 2009;120(4):278–285. doi:10.1161/CIRCULATIONAHA.109.853143.
  • Misra HP, Fridovich I. The generation of superoxide radical during the autoxidation of hemoglobin. J Biol Chem. 1972;247(21):6960–6962.
  • Munakata A, Ohkuma H, Shimamura N. Effect of a free radical scavenger, edaravone, on free radical reactions: related signal transduction and cerebral vasospasm in the rabbit subarachnoid hemorrhage model. Acta Neurochir Suppl 2011;110(Pt 2):17–22. doi:10.1007/978-3-7091-0356-2_4.
  • Handa Y, Kaneko M, Takeuchi H, Tsuchida A, Kobayashi H, Kubota T. Effect of an antioxidant, ebselen, on development of chronic cerebral vasospasm after subarachnoid hemorrhage in primates. Surg Neurol. 2000;53(4):323–329. doi:10.1016/S0090-3019(00)00168-3.
  • Trinity JD, Broxterman RM, Richardson RS. Regulation of exercise blood flow: role of free radicals. Free Radic Biol Med. 2016;98:90–102. doi:10.1016/j.freeradbiomed.2016.01.017.
  • Ganesh D, Kumarathasan P, Thomson EM, St-Germain C, et al. Impact of superoxide dismutase mimetic AEOL 10150 on the endothelin system of Fischer 344 rats. PLoS One. 2016;11(3):e0151810. doi:10.1371/journal.pone.0151810.
  • Livrea MA, Tesoriere L. Lipoperoxyl radical scavenging and antioxidative effects of red beet pigments, in red beet biotechnology. Food Pharm Appl. 2012;6:105–124. doi:10.1007/978-1-4614-3458-0_6.
  • Winkler C, Wirleitner B, Schroecksnadel K, Schennach H, Fuchs D. In vitro effects of beet root juice on stimulated and unstimulated peripheral blood mononuclear cells. Am J Biochem Biotechnol. 2005;1(4):180–185. doi:10.3844/ajbbsp.2005.180.185.
  • Kanner J, Harel S, Granit R. Betalains-a new class of dietary cationized antioxidants. J Agric Food Chem. 2001;49(11):5178–5185.
  • Han J, Ma D, Zhang M, Yang X, Tan D. Natural antioxidant betanin protects rats from paraquat-induced acute lung injury interstitial pneumonia. Biomed Res Int. 2015;2015:1. doi:10.1155/2015/608174.
  • Tan D, Wang Y, Bai B, Yang X, Han J. Betanin attenuates oxidative stres and inflammatory reaction in kidney of paraquat-treated rat. Food Chem Toxicol. 2015;78:141–146. doi:10.1016/j.fct.2015.01.018.
  • Eftekhari A, Ahmadian H, Eghbal MA, Ahmadian E. The protective and antioxidant role of betanin against atrazine-induced toxicity in primary cultured rat hepatocytes. J Adv Chem Pharm Mater (JACPM) 2018;1(1):3–9.
  • Amjadi S, Hamishehkar H, Ghorbani M. A novel smart PEGylated gelatin nanoparticle for co-delivery of doxorubicin and betanin: a strategy for enhancing the therapeutic efficacy of chemotherapy. Mater Sci Eng C Mater Biol Appl. 2019;97:833–841. doi:10.1016/j.msec.2018.12.104.
  • Rahimi P, Abedimanesh S, Mesbah-Namin SA, Ostadrahimi A. Betalains, the nature-inspired pigments, in health and diseases. Crit Rev Food Sci Nutr. 2018;58:1–30. doi:10.1080/10408398.2018.1479830.
  • Kaur G, Thawkar B, Dubey S, Jadhav P. Pharmacological potentials of betalains. J Complement Integr Med. 2018;15(3). doi:10.1515/jcim-2017-0063.

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