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Journal of Investigative Surgery Volume 35, 2022 - Issue 8

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Original Research

Measuring the Systemic Inflammatory Response to On- and Off-Pump Coronary Artery Bypass Graft (CABG) Surgeries Using the Tryptophan/Kynurenine Pathway

Ahmed Farouka Cardiothoracic Surgery Department, Faculty of medicine, Assiut University, Egypt

Rasha A. Hamedb Anesthesia and Intensive Care Department, Faculty of medicine, Assiut University, Egypt

https://orcid.org/0000-0003-3746-7467

Saeid Elsawyc Anesthesia and Pain management, Faculty of medicine, Assiut University, Egypt

Nashwa F. Abd El Hafezd Anesthesia and Intensive Care Department, Faculty of medicine, South Valley, Egypt

Farag M. Moftahe Community Medicine and Medical Statistics, Faculty of medicine, Assiut University, Egypt

Muammar A. Y. Nassarf Biochemistry Department, Faculty of Medicine, Dongola, Sudan

Fify Alfy Gabrag Microbiology Department, Faculty of Science, Assiut University, Assiut, Egypt;i Metabolic and Genetic Disorders Unit, Faculty of medicine, Assiut University, Egypt

Tahia H. Saleemh Biochemistry, Faculty of medicine, Assiut University, Egypt;i Metabolic and Genetic Disorders Unit, Faculty of medicine, Assiut University, EgyptCorrespondence[email protected]

https://orcid.org/0000-0001-8575-4714

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Pages 1621-1625 | Received 06 Mar 2022, Accepted 23 May 2022, Published online: 12 Jun 2022

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https://doi.org/10.1080/08941939.2022.2084188
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Caroline MF, Gillian MM, Lynn O, et al. Kynurenine metabolism predicts cognitive function in patients following cardiac bypass and thoracic surgery. J Neurochem. 2011;119(1):136–152. doi:https://doi.org/10.1111/j.1471-4159.2011.07414.x.
PubMedGoogle Scholar
Hol JW, Stolker RJ, Klimek M, et al. The tryptophan kynurenine pathway, neopterin and IL-6 during vulvectomy and abdominal hysterectomy. J Biomed Sci. 2014;21(1):102. doi:https://doi.org/10.1186/s12929-014-0102-2.
PubMedGoogle Scholar
Sorgdrager FJH, Naudé PJW, Kema IP, et al . Tryptophan metabolism in inflammaging: from biomarker to therapeutic target. Front Immunol. 2019;10:2565. doi:https://doi.org/10.3389/fimmu.2019.02565.
PubMed Web of Science ®Google Scholar
Wang Q, Liu D, Song P, Zou MH . Tryptophan–kynurenine pathway is dysregulated in inflammation, and immune activation. Front Biosci (Landmark Ed). 2015;20(7):1116–1143. doi:https://doi.org/10.2741/4363.
PubMedGoogle Scholar
Badawy AA, Guillemin G . The plasma [kynurenine]/[tryptophan] ratio and indoleamine 2,3-dioxygenase: time for appraisal. Int J Tryptophan Res. 2019;12:1178646919868978. doi:https://doi.org/10.1177/1178646919868978.
Google Scholar
Terlecki P, Pawlik P, Iwaniuk A, et al. Carotid surgery affects plasma kynurenic acid concentration: a pilot study. Med Sci Monit. 2014;20:303–310. doi:https://doi.org/10.12659/MSM.890212.
PubMedGoogle Scholar
Otlinska-Hasiec E, Nowicka-Stazka P, Parada-Turska J, et al. Plasma kynurenic acid concentration in patients undergoing cardiac surgery: effect of anaesthesia. Arch Immunol Ther Exp (Warsz). 2015;63(2):129–137. doi:https://doi.org/10.1007/s00005-014-0312-z.
PubMedGoogle Scholar
Marfella A, Bilancio A, Polese C, et al. Urinary neopterin and kynurenine in patients submitted to surgical stress with different inhalational anesthetics (halothane or isoflurane). Int J Immunopharmacol. 1999;21(7):423–433. doi:https://doi.org/10.1016/S0192-0561(99)00021-1.
PubMedGoogle Scholar
Jawa RS, Anillo S, Huntoon K, et al. Interleukin-6 in surgery, trauma, and critical care part II: clinical implications. J Intensive Care Med. 2011;26(2):73–87. doi:https://doi.org/10.1177/0885066610384188.
PubMedGoogle Scholar
Darlington LG, Mackay GM, Forrest CM, et al. Altered kynurenine metabolism correlates with infarct volume in stroke. Eur J Neurosci. 2007;26(8):2211–2221. doi:https://doi.org/10.1111/j.1460-9568.2007.05838.x.
PubMedGoogle Scholar
Ploder M, Spittler A, Schroecksnadel K, et al. Tryptophan degradation in multiple trauma patients: survivors compared with non-survivors. Clin Sci. 2009;116(7):593–598. doi:https://doi.org/10.1042/CS20080319.
Web of Science ®Google Scholar
Ristagno G, Fries M, Brunelli L, et al. Early kynurenine pathway activation following cardiac arrest in rats, pigs, and humans. Resuscitation. 2013;84(11):1604–1610. doi:https://doi.org/10.1016/j.resuscitation.2013.06.002.
PubMedGoogle Scholar
Zeden JP, Fusch G, Holtfreter B, et al . Excessive tryptophan catabolism along the kynurenine pathway precedes ongoing sepsis in critically ill patients. Anaesth Intensive Care. 2010;38(2):307–316. doi:https://doi.org/10.1177/0310057X1003800213.
PubMedGoogle Scholar
Robinson CM, Hale PT, Carlin JM . The role of IFN-gamma and TNF-alpha-responsive regulatory elements in the synergistic induction of indoleamine dioxygenase. J Interferon Cytokine Res. 2005;25(1):20–30. doi:https://doi.org/10.1089/jir.2005.25.20.
PubMedGoogle Scholar
Simonato M, Fochi I, Vedovelli L, et al. Urinary metabolomics reveals kynurenine pathway perturbation in newborns with transposition of great arteries after surgical repair. Metabolomics. 2019;15(11):145. doi:https://doi.org/10.1007/s11306-019-1605-3.
PubMedGoogle Scholar
Sabapathy D, Klawitter J, Silveira L, et al . Activation of kynurenine pathway of tryptophan metabolism after infant cardiac surgery with cardiopulmonary bypass: a prospective cohort study. Metabolomics. 2020;16(9):93. doi:https://doi.org/10.1007/s11306-020-01714-x.
PubMed Web of Science ®Google Scholar

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Measuring the Systemic Inflammatory Response to On- and Off-Pump Coronary Artery Bypass Graft (CABG) Surgeries Using the Tryptophan/Kynurenine Pathway

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Measuring the Systemic Inflammatory Response to On- and Off-Pump Coronary Artery Bypass Graft (CABG) Surgeries Using the Tryptophan/Kynurenine Pathway

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