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Inhalation Toxicology
International Forum for Respiratory Research
Volume 12, 2000 - Issue 4
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Research Article

POSTTREATMENT WITH ETYA PROTECTS AGAINST PHOSGENE-INDUCED LUNG INJURY BY AMPLIFYING THE GLUTATHIONE TO LIPID PEROXIDATION RATIO

Alfred M. Sciuto Neurotoxicology Branch, Pharmacology Division, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA
Pages 347-356 | Published online: 01 Oct 2008

REFERENCES

  • Buege, J. A., and Aust, S. D. 1978. Microsomal lipid peroxidation. Methods EnzymoL 51:302-310. Chan, A. C., Tran, K., Raynor, T., Ganz, P. R., and Chow, C. K. 1991. Regeneration of vitamin E in human platelets.]. Biol. Chem. 266:17290–17295.
  • Cominacini, L., Garbin, U., De Santis, A., Campagnola, M., Davoli, A., Pasini, A. F., Faccini, G., Pasqualini, E., Bertozzo, L., Micciolo, R., Pastorino, A. M., and Lo Cascio, V. 1996. Mecha-nisms involved in the in vitro modification of low density lipoprotein by human umbilical vein endothelial cells and copper ions.]. Lipid Mediat. Cell Signal1:19–33.
  • Diller, W. F. 1978. Medical phosgene problems and their solutions.]. Occup. Med. 20:189-193. Diller, W. F., and Zante, R. 1982. Dosis-wirkungs-beziehungen bei phosgen-einwirkung auf mensch und tier. Zentralbl. Arbeitsmed. 32(10):360–368.
  • Downing, D. T., Ahern, D. G., and Bachta, M. 1970. Enzyme inhibition by acetylenic acids. Biochem. Biophys. Res. Commun. 40:218–223.
  • Farrukh, I. S., Michaels, J. R., Peters, S. P., Sciuto, A. M., Adkinson, N. F., Freeland, H. S., Paky, A., Spanhaake, E. W., Summer, W. R., and Gurtner, G. H. 1988. The role of cyclooxygenase and lipoxygenase mediators in oxidant-induced lung injury. Am. Rev. Respir. Dis. 137:1343–1349.
  • Fujita, M., Nakagawa, Y., Osawa, R., Kijima-Suda, I., Setaka, M., Nojima, S., and Tomita, K. 1994. Differences related to the production of arachidonic acid between collagen- and thrombin-stim-ulated human platelets.]. Biochem. 116:269–273.
  • Guo, Y.-L., Kennedy, T. P., Michael, J. R., Sciuto, A. M., Ghio, A. J., Adkinson, N. F., and Gurtner, G. H. 1990. Mechanisms of phosgene-induced lung injury: Role of arachidonate mediators.]. Appl. Physiol. 69:1615–1622.
  • Halliwell, B., and Gutteridge, J. M. C. 1990. The antioxidants in human extracellular fluids. Arch. Biochem. Biophys. 280(1):1–8.
  • Kuhn, H., Holzhütter, H.-G., Schewe, T., Hiebsch, C., and Rapoport, S. M. 1984. The mechanism of inactivation of I ipoxygenase by acetylenic fatty acids. Eur. J. Biochem. 139: 577–583.
  • Lowry, 0. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. 1951. Protein measurement with Folin phenol reagent.]. Biol. Chem. 193: 265–275.
  • Reed, D. J. 1986. Regulation of reductive processes by glutathione. Biochem. Pharmacol. 35(1):7-13. Sciuto, A. M. 1997. Ibuprofen treatment enhances the survival of mice following exposure to phos-gene. lnhal. Toxicol. 9:389–403.
  • Sciuto, A. M. 1998. Assessment of early acute lung injury in rodents exposed to phosgene. Arch. ToxicoL 283–288.
  • Sciuto, A. M., and Stotts, R. R. 1998. Posttreatment with eicosatetrayroic acid decreases lung edema in guinea pigs exposed to phosgene: The role of leukotrienes. Exp. Lung Res. 24:273–292.
  • Sciuto, A. M., Strickland, P. T., Kennedy, T. P., and Gurtner, G. H. 1995. Protective effects of N-acetylcysteine treatment after phosgene exposure in rabbits. Am.]. Respir. Crit. Care Med. 151: 768–772.
  • Sciuto, A. M., Strickland, P. T., Kennedy, T. P., and Gurtner, G. H. 1997. Postexposure treatment with aminophylline protects against phosgene-induced acute lung injury. Exp. Lung Res. 23(4): 317–332.
  • Sciuto, A. M., Strickland, P. T., Kennedy, T. P., and Gurtner, G. H. 1998. Post-exposure treatment with isoproterenol attenuates pulmonary edema in phosgene-exposed rabbits. J. Appl. ToxicoL 18:321–329.
  • Suzukawa, M., Abbey, M., Clifton, P., and Neste, P. J. 1996. Enhanced capacity of n-3 fatty acid-enriched macrophages to oxidize low density lipoprotein mechanisms and effects of antioxidant enzymes. Atherosclerosis 124(2):157–169.
  • Tietze, F. 1969. Enzymatic method for the quantitative determination of nanogram amounts of total and oxidized glutathione. Anal. Biochem. 27:502–522.
  • Uchiyama, M., and Mihara, M. 1978. Determination of malondialdehyde (mda) precursors in tissue by thiobarbituric acid test. Anal. Biochem. 86:271–278.
  • Wong, S. H. Y., Knight, J. A., Hopfer, S. M., Zaharia, 0., Leach, C. N., and Sunderman, F. W. 1982. Lipoperoxides in plasma as measured by liquid chromatographic separation of malondialdehyde (mda)—thiobarbituric acid adduct. Clin. Chem. 33(2):214–220.

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