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Inhalation Toxicology
International Forum for Respiratory Research
Volume 14, 2002 - Issue 5
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Research Article

FUNGAL SPORES AS SUCH DO NOT CAUSE NASAL INFLAMMATION IN MOLD EXPOSURE

M. Roponen Laboratory of Toxicology, National Public Health Institute, Kuopio, Finland
,
M. Seuri Kuopio Regional Institute of Occupational Health, Kuopio, Finland
,
A. Nevalainen Laboratory of Environmental Microbiology, National Public Health Institute, Kuopio, Finland, and Department of Health Evaluation Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA
&
M.-R. Hirvonen Laboratory of Toxicology, National Public Health Institute, Kuopio, Finland
Pages 541-549 | Published online: 01 Oct 2008

  • Alwis, K. U., Mandryk, J., and Hocking, A. D. 1999. Exposure to biohazards in wood dust: Bacteria, fungi, endotoxins, and (1->3)-ß-D-glucans. App. Occup. Environ. Hyg. 14:598-608.
  • Belin, L. 1987. Sawmill alveolitis in Sweden. Int. Arch. Allergy Appl. ImmunoL 82:440-443.
  • Cormier, Y., Mérlaux, A., and Duchaine, C. 2000. Respiratory health impact of working in sawmills in eastern Canada. Arch. Environ. Health 55:424-430.
  • Dahlqvist, M., Palmberg, L., Malmberg, P., Sundblad, B.-M., Ulfvarson, U., and Zhiping, W. 1996. Acute effects of exposure to air contaminants in a sawmill on healthy volunteers. Occup. Environ. Med. 53:586-590.
  • Douwes, J., McLean, D., van der Maarl, E., Heederik, D., and Pearce, N. 2000a. Worker exposures to airborne dust, endotoxin and beta(1,3)-glucan in two New Zealand sawmills. Am. J. Ind. Med. 38:426-430.
  • Douwes, J., Wouters, I., Dubbeld, H., van Zwieten, L, Steerenberg, P., Doekes, G., and Heederik, D. 2000b. Upper airway inflammation assessed by nasal lavage in compost workers: A relation with bio-aerosol exposure. Am. J. Ind. Med. 37:459-468.
  • Eduard, W., Sandven, P., and Levy, F. 1993. Serum IgG antibodies to mold spores in two Norwegian sawmill populations: Relationship to respiratory and other work-related symptoms. Am. J. Ind. Med. 24:207-222.
  • Eduard, W., Sandven, P., and Levy, F. 1994. Exposure and IgG antibodies to mold spores in wood trimmers: Exposure-response relationships with respiratory symptoms. App. Occup. Environ. Hyg. 9:44-48.
  • Eriksson, K. A., Stjernberg, N. L., Levin, J. O., Hammarstrom, U., and Ledin, M. C. 1996. Terpene exposure and respiratory effects among sawmill workers. Scand. J. Work Environ. Health 22: 182-190.
  • Green, L. C., Wagner, D. A., Glogowski, J., Skipper, P. L., Wishnok, J. S., and Tannenbaum, S. R. 1982. Analysis of nitrate, nitrite and [15N]nitrate in biological fluids. Anal. Biochem. 126:131-138.
  • Halpin, D. M. G., Graneek, B. J., Lacey, J., Nieuwenhuijsen, M. J., Williamson, P. A. M., Venables, K. M., and Newman Taylor, A. J. 1994. Respiratory symptoms, immunological responses, and aeroallergen concentrations at a sawmill. Occup. Environ. Med. 51:165-172.
  • Hessel, P. A., Herbert, F. A., Melenka, L. S., Yoshida, K., Michaelchuk, D., and Nakaza, M. 1995. Lung health in sawmill workers exposed to pine and spruce. Chest 108:642-646.
  • Hirvonen, M.-R., Nevalainen, A., Makkonen, N., Mönkkönen, J., and Savolainen, K. 1997. Induced production of nitric oxide, tumor necrosis factor, and interleukin-6 in RAW264.7 macrophages by Streptomycetes from indoor air of moldy houses. Arch. Environ. Health 52:426-432.
  • Hirvonen, M.-R., Ruotsalainen, M., Roponen, M., Hyvärinen, A., Husman, T., Kosma, V.-M., Komulainen, H., Savolainen, K., and Nevalainen, A. 1999. Nitric oxide and proinflammatory cytokines in nasal lavage fluid associated with symptoms and exposure to moldy building microbes. Am.). Respir. Crit. Care Med. 160:1943-1946.
  • Hirvonen, M.-R., Suutari, M., Ruotsalainen, M., Lignell, U., and Nevalainen, A. 2001. Effect of growth medium on potential of Streptomyces anulatus spores to induce inflammatory responses and cytotoxicity in RAW264.7 macrophages. Inhal. Toxicol. 13:55-68.
  • Husman, T. 1996. Health effects of indoor-air micro-organisms. Scand. J. Work Environ. Health 22:5-13.
  • Huttunen, K., Ruotsalainen, M., livanainen, E., Torkko, P., KatiIa, M.-L, and Hirvonen, M.-R. 2000. Inflammatory responses in RAW264.7 macrophages caused by mycobacteria isolated from moldy houses. Environ. Toxicol. Pharmacol. 8:237-244.
  • Johard, U., Eklund, A., Dahlqvist, M., Ahlander, A., Alexandersson, R., Ekholm, U., Tomling, G., and Ulfvarsson, U. 1992. Signs of alveolar inflammation in non-smoking Swedish wood trimmers. Br. J. Ind. Med. 49:428-434.
  • Johard, U., Larsson, K., Lof, A., and Eklund, A. 1993. Controlled short-time terpene exposure induces an increase of the macrophages and the mast cells in bronchoalveolar lavage fluid. Am. J. Ind. Med. 23:793-799.
  • Malmberg, P. O., Rask-Andersen, A., Larsson, K. Å., Stjernberg, N., Sundblad, B.-M., and Eriksson, K. 1996. Increased bronchial responsiveness in workers sawing Scots pine. Am. J. Respir. Crit. Care Med. 153:948-952.
  • Mandryk, J., Alwis, K. U., and Hocking, A. D. 2000. Effects of personal exposures on pulmonary function and work-related symptoms among sawmill workers. Ann. Occup. Hyg. 44:281-289.
  • Meklin, T., Husman, T., Vepsäläinen, A., Vahteristo, M., Koivisto, J., Halla-aho, J., Hyvärinen, A., Moschandreas, D., and Nevalainen, A. 2001. Indoor air microbes and respiratory symptoms of children in moisture damaged and reference schools. Indoor Air, in press.
  • Murtoniemi, T., Nevalainen, A., Suutari, M., Toivola, M., Komulainen, H., and Hirvonen, M.-R. 2001. Induction of cytotoxicity and production of inflammatory mediators in RAW264.7 macrophages by spores grown on six different plasterboards. lnhal. Toxicol. 13:233-247.
  • Palmgren, U., Ström, G., Blomquist, G., and Malmberg, P. 1986. Collection of airborne micro-organ-isms on Nuclepore filters, estimation and analysis-CAMNEA method. J. Appl. Bacteriol. 61: 401-406.
  • Peat, J. K., Dickerson, J., and Li, J. 1998. Effects of damp and mould in the home on respiratory health: A review of the literature. Allergy 53:120-128.
  • Roponen, M., Toivola, M., Meklin, T., Ruotsalainen, M., Komulainen, H., Nevalainen, A., and Hirvonen, M.-R. 2001. Differences in inflammatory responses and cytotoxicity in RAW264.7 macrophages induced by Streptomyces anulatus grown on different building materials. Indoor Air 11:179-184.
  • SFS Certification. 1978. Measurement of organic vapors in workplace air with charcoal tube method. SFS 3861 (in Finnish). Helsinki, Finland: SFS, Finnish Standards Association.
  • Terho, E. O., Husman, K., Kotimaa, M., and Sjöblom, T. 1980. Extrinsic allergic alveolitis in a sawmill worker. Scand. j. Work Environ. Health 6:153-157.
  • Toivola, M., Reiman, M., Hyvärinen, A., Meklin, T., and Nevalainen A. 1999. Different methods to characterize moldy buildings. In Bioaerosols, fungi and mycotoxins: Health Effects, Assessment, Prevention and Control, ed. E. Johanning, pp. 453-456. Albany, NY: Eastern New York Occupational and Environmental Health Center.

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