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Inhalation Toxicology
International Forum for Respiratory Research
Volume 15, 2003 - Issue 10
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Research Article

Man-Made Mineral Fiber Hazardous Properties Assessment Using Transgenic Rodents: Example of Glass Fiber Testing

M. C. Bottin Institut National de Recherche et de Sécurité, Vandoeuvre Cedex, France
,
J. C. Vigneron Institut National de Recherche et de Sécurité, Vandoeuvre Cedex, France
,
R. Rousseau Institut National de Recherche et de Sécurité, Vandoeuvre Cedex, France
,
J. C. Micillino Institut National de Recherche et de Sécurité, Vandoeuvre Cedex, France
,
C. Eypert-Blaison Institut National de Recherche et de Sécurité, Vandoeuvre Cedex, France
,
E. Kauffer Institut National de Recherche et de Sécurité, Vandoeuvre Cedex, France
,
P. Martin Institut National de Recherche et de Sécurité, Vandoeuvre Cedex, France
,
S. Binet Institut National de Recherche et de Sécurité, Vandoeuvre Cedex, France
&
B. H. Rihn Institut National de Recherche et de Sécurité, Vandoeuvre Cedex, France
 show all
Pages 1017-1027 | Published online: 01 Oct 2008

  • Anonymous. 1996. Consensus report. International Agency for Research on Cancer. Mechanisms of fibre carcinogenesis. IARC Sci. Publ. 140:1-9.
  • Bellmann, B., Muhle, H., Creutzenberg, O., Ernst, H., Brown, R. C., and Sebastien, P. 2001. Effects of nonfibrous particles on ceramic fiber (RCF1) toxicity in rats, Inhal. Toxicol. 13:877-901.
  • Bernstein, D. M., Morscheidt, C., Grimm, H.G., Thévenaz, P., and Teichert, U. 1996. Evaluation of soluble fibers using the inhalation biopersistence model, a nine-fiber comparison, Inhal. Toxicol. 8:345-385.
  • Bernstein, D. M., and Riego Si n tes, J. M., eds. 1999. Methods for the determination of the hazardous properties for human health of man made mineral fibres (MMMF). European Commission Joint Center, Institute for Health and Consumer Protection, Unit: Toxicology and Chemical Substances, European Chemicals Bureau, EUR 18748EN, April. http://ecb.ei.jrc.it/DOCUMENTS/Testing-Methods/ mmmfweb.pdf
  • Bernstein, D. M., Riego Sintes, J. M., Ersboell, B. K., and Kunert, J. 2001 a. Biopersistence of synthetic mineral fibers as a predictor of chronic inhalation toxicity in rats, Inhal. Toxicol. 13:823-849.
  • Bernstein, D. M., Riego Sintes, J. M., Ersboell, B. K., and Kunert, J. 2001 b. Biopersistence of synthetic mineral fibers as a predictor of chronic intraperitoneal injection tumor response in rats, Inhal. Toxicol. 13:851-875.
  • Big Blue transgenic rodent mutagenesis assay system. Instruction manual. 1997. Revision c027002. La Jolla, CA: Stratagene.
  • Brown, R. C., Sebastien, P., Bellmann, B., and Muhle, H. 2000. Particles contamination in experimental fiber preparations, Inhal. Toxicol. 12:S99-103.
  • Everitt, J. I. 1994. Mechanisms of fiber-induced diseases: Implications for the safety evaluation of synthetic vitreous fibers. Regul. Toxicol. Pharmacol. 20:568-75.
  • Expertise collective de I'INSERM. Effets sur la santé des fibres de substitution à l'amiante. 1999. Paris: Les Editions INSERM.
  • Hesterberg, T. W., Hart, G. A., Chevalier, J., Miiller, W. C., Hamilton, R. D., Bauer, J., and Thevenaz, P. 1998. The importance of fiber biopersistence and lung dose in determining the chronic inhalation effects of X607, RCF1, and chrysotile asbestos in rats. Toxicol. Appl. Pharmacol. 153:68-82.
  • Hesterberg, T. W., Hart, G. A., Miller, W. C., Chase, G., Rogers, R. A., Mangum, J. B., and Everitt, J. I. 2002. Use of short-term assays to evaluate the potential toxicity of two new biosoluble glasswool fibers, Inhal. Toxicol. 14:217-246.
  • Kamstrup, O., Davis, J. M., Ellehauge, A., and Guldberg, M. 1998. The biopersistence and pathogenicity of man-made vitreous fibres after short-and long-term inhalation. Ann. Occup. Hyg. 42:191-199.
  • McDonald, J. C. 1998. Mineral fibre persistence and carcinogenicity. Ind. Health 36:372-375.
  • Micillino, J. C., Coulais, C., Bottin, M.-C., Monhoven, N., Binet, S., Keith, G., and Rihn, B. H. 2002. Lack of genotoxicity of bitumen in lung of transgenic mice. Toxicology 170:11-20.
  • Miller, B. G., Jones, A. D., Searl, A., Buchanan, D., Cullen, R. T., Soutar, C. A., Davis, J. M., and Donaldson, K. 1999. Influence of characteristics of inhaled fibres on development of tumours in the rat lung. Ann. Occup. Hyg. 43:167-179.
  • Moolgavkar, S. H., Brown, R. C., and Turim, J. 2001a. Biopersistence, fiber length, and cancer risk assessment for inhaled fibers, Inhal. Toxicol. 13:755-772.
  • Moolgavkar, S. H., Turim, J., and Brown, R. C. 2001b. The power of the European Union protocol to test for carcinogenicity of inhaled fibers. Regul. Toxicol. Pharmacol. 33:350-355.
  • Muhle, H., and Bellmann, B. 1995. Biopersistence of man-made vitreous fibres. Ann. Occup. Hyg. 39:655-660.
  • Rihn, B., Kauffer, E., Martin, P., Coulais, C., Villa, M., Bottin, M. C., Vigneron, J. C., Edorh, A., and Martinet, N. 1996. Short-term crocidolite inhalation studies in mice: Validation of an inhalation chamber. Toxicology 109:147-156.
  • Rihn, B. H., Bottin, M. C., Coulais, C., Rouget, R., Monhoven, N., Baranowski, W., Edorh, A., and Keith, G. 2000a. Genotoxicity of 3-methylcholanthrene in liver of transgenic Big Blue mice. Environ. Mol. Mutagen. 36:266-273.
  • Rihn, B., Coulais, C., Kauffer, E., Bottin, M. C., Martin, P., Yvon, F., Vigneron, J. C., Binet, S., Monhoven, N., Steiblen, G., and Keith, G. 2000b. Inhaled crocidolite mutagenicity in lung DNA. Environ. Health Perspect. 108:341-346.
  • Unfried, K., Schurkes, C, and Abel, J. 2002. Distinct spectrum of mutations induced by crocidolite asbestos: Clue for 8-hydroxydeoxyguanosine-dependent mutagenesis in vivo. Cancer Res. 62:99-104.

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