REFERENCES
- Andersen M. E., Gargas M. L., Jones R. A., Jenkins L. J., Jr. The use of inhalation techniques to assess the kinetic constants of 1,1- dichloroethylene metabolism. Toxicol. Appl. Pharmacol. 1979; 47: 395–409, [PUBMED], [INFOTRIEVE]
- Borghoff S. J, Murphy J. E., Medinsky M. A. Development of physiologically based pharmacokinetic model for methyl tertiary-butyl ether and tertiary-butanol in male Fisher-344 rats. Fundam. Appl. Toxicol. 1996; 30: 264–75, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Dennison J. E., Andersen M. E., Yang R. S. H. Characterization of the pharmacokinetics of gasoline using PBPK modeling with a complex mixtures chemical lumping approach. Inhal. Toxicol. 2003; 15: 961–86, [PUBMED], [INFOTRIEVE], [CSA]
- Dennison J. E., Andersen M. E., Clewell H. J., Yang R. S. H. Development of a PBPK model for volatile fractions of gasoline using chemical lumping analysis. Environ Sci Tech 2004; 38: 5674–81, [CROSSREF], [CSA]
- El-Masri H. A., Constan A. A., Ramsdell H. S., Yang R. S. Physiologically based pharmacodynamic modeling of an interaction threshold between trichloroethylene and 1,1-dichloroethylene in Fischer 344 rats. Toxicol. Appl. Pharmacol. 1996; 141: 124–32, [PUBMED], [INFOTRIEVE], [CSA]
- Filser J. G. The closed chamber technique–uptake, endogenous production, excretion, steady-state kinetics and rates of metabolism of gases and vapors. Arch. Toxicol. 1992; 66: 1–10, [PUBMED], [INFOTRIEVE]
- Filser J. G., Bolt H. M. Pharmacokinetics of halogenated ethylenes in rats. Arch. Toxicol. 1979; 42: 123–36, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Fukuda Y. Maintenance of ventilatory control by CO2 in the rat during growth and aging. Pflugers Arch. 1991; 419: 38–42, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Ganong W. F. Review of Medical Physiology, 13th ed. Appleton and Lange, Norwalk, CN 1987; 563
- Gargas M. L., Andersen M. E., Clewell H. J. D. A physiologically based simulation approach for determining metabolic constants from gas uptake data. Toxicol. Appl. Pharmacol. 1986; 86: 341–52, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Gargas M. L., Burgess R. J., Voisard D. E., Cason G. H., Andersen M. E. Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues. Toxicol. Appl. Pharmacol. 1989; 98: 87–99, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Gargas M. L., Clewell H. J., Andersen M. E. Gas uptake inhalation techniques and the rates of metabolism of chloromethanes, chloroethanes, and chloroethylenes in the rat. Inhal. Toxicol. 1990; 2: 295–319
- Hefner R. E., Jr., Watanabe P. G., Gehring P. J. Preliminary studies on the fate of inhaled vinyl chloride monomer (VCM) in rats. Environ. Health Perspect. 1975; 11: 85–95, [PUBMED], [INFOTRIEVE]
- Hilderbrand R. L., Andersen M. E., Jenkins L. J., Jr. Prediction of in vivo kinetic constants for metabolism of inhaled vapors from kinetic constants measured in vitro. Fundam. Appl. Toxicol. 1981; 1: 403–9, [PUBMED], [INFOTRIEVE]
- Hwang I. Y., Reardon K. F., Tessari J. D., Yang R. S. A gas-liquid system for enzyme kinetic studies of volatile organic chemicals. Determination of enzyme kinetic constants and partition coefficients of trichloroethylene. Drug Metab. Dispos. 1996; 24: 377–82, [PUBMED], [INFOTRIEVE], [CSA]
- Liao K. H., Dobrev I. D., Dennison J. E., Jr., Andersen M. E., Reisfeld B., Reardon K. F., Campain J. A., Wei W., Klein M. T., Quann R. J., Yang R. S. Application of biologically based computer modeling to simple or complex mixtures. Environ. Health Perspect. 2002; 110: 957–63, Suppl 6[PUBMED], [INFOTRIEVE]
- Lilly P. D., Andersen M. E., Ross T. M., Pegram R. A. Physiologically based estimation of in vivo rates of bromodichloromethane metabolism. Toxicology 1997; 124: 141–152, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Lutz W. K., Schlatter C. A closed inhalation system for pharmacokinetic and metabolism studies of volatile compounds with small laboratory animals. Arch. Toxicol. Suppl. 1978; 373–5
- McGee J. K., Evans M. V., Crank W. D. A versatile gas uptake inhalation system used in pharmacokinetic and metabolic studies of volatile organic compounds. Toxicol Meth 1995; 5: 199–212
- Macey R. I., Oster G. F. Berkeley Madonna. University of California, Berkeley, CA 2002, Available: http://www.berkeleymadonna.com/ [accessed 20 Sept 2002]
- Schlosser P. M., Lilly P. D., Conolly R. B., Janszen D. B., Kimbell J. S. Benchmark dose risk assessment for formaldehyde using airflow modeling and a single-compartment, DNA-protein cross-link dosimetry model to estimate human equivalent doses. Risk Anal. 2003; 23: 473–87, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Thrall K. D., Soelberg J. J., Weitz K. K., Woodstock A. D. Development of a physiologically based pharmacokinetic model for methyl ethyl ketone in F344 rats. J Toxicol Environ Health A 2002; 65: 881–96, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Timchalk C., Nolan R. J., Mendrala A. L., Dittenber D. A., Brzak K. A., Mattsson J. L. A Physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model for the organophosphate insecticide chlorpyrifos in rats and humans. Toxicol Sci. 2002; 66: 34–53, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Tornero-Velez R., Laskey J., Evans M. In vitro determination of kinetic constants for 1,3-dichloropropane, 2,2-dichloropropane, and 1,2-dichloropropane in rat liver microsomes and cytosol. Toxicologist 2003; 72