Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 19, 2007 - Issue 5
118
Views
14
CrossRef citations to date
0
Altmetric
Research Article

Histological Alterations in Male A/J Mice Following Nose-Only Exposure to Tobacco Smoke

, , , , &
Pages 405-418 | Received 30 May 2006, Accepted 01 Dec 2006, Published online: 06 Oct 2008

REFERENCES

  • Agresti A. An introduction to categorical data analysis. John Wiley & Sons, New York 1996
  • Auerbach O., Forman J. B., Gere J. B., Kassouny D. Y., Muehsam G. E., Petrick T. G., Smolin H. J., Stout A. P. Changes in the bronchial epithelium in relation to smoking and cancer of the lung; A report of progress. N. Engl. J. Med. 1957; 256(3)97–104
  • Auerbach O., Stout A. P., Hammond E. C., Garfinkel L. Changes in bronchial epithelium in relation to cigarette smoking and in relation to lung cancer. N. Engl. J. Med. 1961; 265(6)253–267
  • Bauer A. K., Dwyer-Nield L. D., Hankin J. A., Murphy R. C., Malkinson A. M. The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice. Toxicology 2001; 169(1)1–15
  • Coggins C. R., Fouillet X. L., Lam R., Morgan K. T. Cigarette smoke induced pathology of the rat respiratory tract: A comparison of the effects of the particulate and vapour phases. Toxicology 1980; 16(2)83–101
  • Coggins C. R. E. A review of chronic inhalation studies with mainstream cigarette smoke in rats and mice. Toxicol. Pathol. 1998; 26(3)307–314
  • Coggins C. Chronic inhalation studies with mainstream cigarette smoke in rats and mice. Toxicol. Pathol. 2000; 28(5)754
  • Coggins C. R. A review of chronic inhalation studies with mainstream cigarette smoke, in hamsters, dogs, and nonhuman primates. Toxicol. Pathol. 2001; 29(5)550–557
  • Coggins C. R. A minireview of chronic animal inhalation studies with mainstream cigarette smoke. Inhal. Toxicol. 2002; 14(10)991–1002
  • Curtin G. M., Higuchi M. A., Ayres P. H., Swauger J. E., Mosberg A. T. Lung tumorigenicity in A/J and rasH2 transgenic mice following mainstream tobacco smoke inhalation. Toxicol. Sci. 2004; 81(1)26–34
  • D'Agostini F., Balansky R. M., Bennicelli C., Lubet R. A., Kelloff G. J., De Flora S. Pilot studies evaluating the lung tumor yield in cigarette smoke-exposed mice. Int. J. Oncol. 2001; 18(3)607–615
  • D'Agostini F., Balansky R. M., Bennicelli C., Lubet R. A., Kelloff G. J., De Flora S., D'hulst A. I., Vermaelen K. Y., Brusselle G. G., Joos G. F., Pauwels R. A. Time course of cigarette smoke-induced pulmonary inflammation in mice. Eur. Respir. J. 2005; 26(2)204–213
  • Dixon D., Horton J., Haseman J. K., Talley F., Greenwell A., Nettesheim P., Hook G. E., Maronpot R. R. Histomorphology and ultrastructure of spontaneous pulmonary neoplasms in strain A mice. Exp. Lung Res. 1991; 17(2)131–155
  • Dungworth D. L., Schwartz L. W., Tyler W. S. Morphological methods for evaluation of pulmonary toxicity in animals. Annu. Rev. Pharmacol. Toxicol. 1976; 16: 381–399
  • Duperron C., Castonguay A. Chemopreventive efficacies of aspirin and sulindac against lung tumorigenesis in A/J mice. Carcinogenesis 1997; 18(5)1001–1006
  • Estensen R. D., Jordan M. M., Wiedmann T. S., Galbraith A. R., Steele V. E., Wattenberg L. W. Effect of chemopreventive agents on separate stages of progression of benzo[a]pyrene induced lung tumors in A/J mice. Carcinogenesis 2004; 25(2)197–201
  • Finch G. L., Nikula K. J., Belinsky S. A., Barr E. B., Stoner G. D., Lechner J. F. Failure of cigarette smoke to induce or promote lung cancer in the A/J mouse. Cancer Lett. 1996; 99(2)161–167
  • Hazelton W. D., Clements M. S., Moolgavkar S. H. Multistage carcinogenesis and lung cancer mortality in three cohorts. Cancer Epidemiol. Biomarkers Prev. 2005; 14(5)1171–1181
  • Hecht S. S. Carcinogenicity studies of inhaled cigarette smoke in laboratory animals: Old and new. Carcinogenesis 2005; 26(9)1488–1492
  • Heck J. D., Gaworski C. L., Rajendran R., Morrissey R. L. Toxicological evaluation of humectants added to cigarette tobacco: 13-Week smoke inhalation study of glycerin and propylene glycol in Fischer 344 rats. Inhal. Toxicol. 2002; 14(11)1135–1152
  • Hutt J. A., Vuillemenot B. R., Barr E. B., Grimes M. J., Hahn F. F., Hobbs C. H., March T. H., Gigliotti A. P., Seilkop S. K., Finch G. L., Mauderly J. L., Belinsky S. A. Life-span inhalation exposure to mainstream cigarette smoke induces lung cancer in B6C3F1 mice through genetic and epigenetic pathways. Carcinogenesis 2005; 26(11)1999–2009
  • International Agency for Research on Cancer. Tobacco smoke and involuntary smoking. IARC Monogr. Eval. Carcinogen. Risks Hum 2004; 83: 1452
  • Malkinson A. M. Molecular comparison of human and mouse pulmonary adenocarcinomas. Exp. Lung Res. 1998; 24(4)541–555
  • Moody T. W., Leyton J., Zakowicz H., Hida T., Kang Y., Jakowlew S., You L., Ozbun L., Zia H., Youngberg J., Malkinson A. Indomethacin reduces lung adenoma number in A/J mice. Anticancer Res. 2001; 21(3B)1749–1755
  • Pashko L. L., Schwartz A. G. Inhibition of 7,12-dimethylbenz[a]anthracene-induced lung tumorigenesis in A/J mice by food restriction is reversed by adrenalectomy. Carcinogenesis. 1996; 17(2)209–212
  • Richter S. J., Higgins J. J. SAS Companion for nonparametric statistics. Thomson/Brooks Cole, Pacific Grove, CA 2006
  • Seagrave J., Barr E. B., March T. H., Nikula K. J. Effects of cigarette smoke exposure and cessation on inflammatory cells and matrix metalloproteinase activity in mice. Exp. Lung Res. 2004; 30(1)1–15
  • Smith C. J., Perfetti T. A., King J. A. Perspectives on pulmonary inflammation and lung cancer risk in cigarette smokers. Inhal. Toxicol. 2006; 18(9)667–677
  • Stinn W., Teredesai A., Kuhl P., Knorr-Wittmann C., Kindt R., Coggins C., Haussmann H. J. Mechanisms involved in A/J mouse lung tumorigenesis induced by inhalation of an environmental tobacco smoke surrogate. Inhal. Toxicol. 2005; 17(6)263–276
  • Van Vunakis H., Gjika H. B., Langone J. J. Environmental carcinogens, Methods of analysis and exposure measurement, Vol. 9: Passive smoking. IARC, Lyon 1987
  • Wingo P. A., Ries L. A., Giovino G. A., Miller D. S., Rosenberg H. M., Shopland D. R., Thun M. J., Edwards B. K. Annual report to the nation on the status of cancer, 1973–1996, with a special section on lung cancer and tobacco smoking. J. Natl. Cancer Inst. 1999; 91(8)675–690
  • Witschi H., Espiritu I., Peake J. L., Wu K., Maronpot R. R., Pinkerton K. E. The carcinogenicity of environmental tobacco smoke. Carcinogenesis 1997; 18(3)575–586
  • Witschi H. Successful and not so successful chemoprevention of tobacco smoke-induced lung tumors. Exp. Lung Res. 2000; 26(8)743–755
  • Witschi H., Uyeminami D., Moran D., Espiritu I. Chemoprevention of tobacco-smoke lung carcinogenesis in mice after cessation of smoke exposure. Carcinogenesis 2000; 21(5)977–982
  • Witschi H., Espiritu I., Uyeminami D., Suffia M., Pinkerton K. E. Lung tumor response in strain a mice exposed to tobacco smoke: Some dose-effect relationships. Inhal. Toxicol. 2004; 16(1)27–32
  • Witschi H. A/J mouse as a model for lung tumorigenesis caused by tobacco smoke: strengths and weaknesses. Exp. Lung Res. 2005a; 31(1)3–18
  • Witschi H. The complexities of an apparently simple lung tumor model: The A/J mouse. Exp. Toxicol. Pathol. 2005b; 57: 171–181, suppl. 1
  • Witschi H., Espiritu I., Ly M., Uyeminami D. The chemopreventive effects of orally administered dexamethasone in strain A/J mice following cessation of smoke exposure. Inhal. Toxicol. 2005; 17(2)119–122
  • Young J. T. Histopathologic examination of the rat nasal cavity. Fundam. Appl. Toxicol. 1981; 1(4)309–312

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.