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Inhalation Toxicology
International Forum for Respiratory Research
Volume 21, 2009 - Issue 7
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Research Article

Exposure to cigarette smoke upregulates AP-1 activity and induces TNF-alpha overexpression in mouse lungs

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Pages 641-647 | Received 14 Jun 2008, Accepted 05 Jul 2008, Published online: 01 Jun 2009

References

  • Barnes, P.J., D.M., D.Sc., and Karin M. 1997. Nuclear factor-κB—A pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336:1066–1071.
  • Calveriey, P. M. A., MacNee, W., Pride, N. B., and Rennard, S. I. 2003. Chronic obstructive pulmonary disease, 2nd ed., pp. 131–134. London: Arnold.
  • Church, T., and Pryor, V. A. 1985. Free radical chemistry of cigarette smoke and its toxicological implications. Environ. Health Perspect. 46:111–126.
  • Churg, A., Wang, R.D., Tai, H., Wang, X., Xie, C., Wright, J.L. 2004. Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse. Am. J. Respir. Crit. Care Med. 170:492–498.
  • Costa, C., Rufino, R., Traves, S.L., Lapa E Silva, J.R., Barnes, P.J., Donnelly, L.E. 2008. CXCR3 and CCR5 chemokines in induced sputum from patients with COPD. Chest 133:26–33.
  • Delerive, P., De Bosscher K., Besnard, S., et al. 1999. Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J. Biol. Chem. 274:32048–32054.
  • Demirjian, L., Abboud, R.T., Li, H., Duronio, V. 2006. Acute effect of cigarette smoke on TNF-alpha release by macrophages mediated through the erk1/2 pathway. Biochim. Biophys. Acta 1762:592–597.
  • Demoly, P., Chanez, P., Pujol, J.L., Gauthier-Rouvière, C., Michel, F.B., Godard, P., Bousquet, J. 1995. Fos immunoreactivity assessment on human normal and pathological bronchial biopsies. Respir. Med. 89:329–335.
  • Di Stefano, A., Caramori, G., Oates, T., Capelli, A., Lusuardi, M., Gnemmi, I., Ioli, F., chung, K.F., Donner, C.F., Barnes, P.J., Adcock, I.M. 2002. Increased expression of nuclear factor-kappaB in bronchial biopsies from smokers and patients with COPD. Eur. Respir. J. 20:556–563.
  • Finkelstein, R., Fraser, R.S., Ghezzo, H., Cosio, M.G. 1995. Alveolar inflammation and its relation to emphysema in smokers. Am. J. Crit. Care Med. 152:1666–1672.
  • Fournier, M., Lebargy, F., Ladurie, F.L.R., Lenormand, E., and Pariente, R. 1989. Intraepithelial T-lymphocyte subsets in the airways of normal subjects and of patients with chronic bronchitis. Am. Rev. Respir. Dis. 140:737–742.
  • Gensch, E., Gallup, M., Sucher, A., Li, D., Gebremichael, A., Lemjabbar, H., Mengistab, A., Dasari, V., Hotchkiss, J., Harkema, J., Basbaum, C. 2004. Tobacco smoke control of mucin production in lung cells requires oxygen radicals AP-1 and JNK. J. Biol. Chem. 279:39085–39093.
  • Grashoff, W.F., Sont, J.K., Sterk, P.J., Hiemstra, P.S., de Boer, W.I., Stolk, J., Han, J., van Krieken, J.M., Grashoff, W.F., Sont, J.K., Sterk, P.J., Hiemstra, P.S., de Boer, W.I., Stolk, J., Han, J., van Krieken, J.M. 1997. Chronic obstructive pulmonary disease: Role of bronchiolar mast cells and macrophages. Am. J. Pathol. 151:1785–1790.
  • D’hulst, A.I., Vermaelen, K.Y., Brusselle, G.G., Joos, G.F., Pauwels, R.A. 2005. Time course of cigarette smoke-induced pulmonary inflammation in mice. Eur. Respir. J. 26:204–213.
  • Ito, K., Hanazawa, T., Tomita, K., Barnes, P. J., and Adcock, I. M. 2004. Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration. Biochem. Biophys. Res. Commun. 315:240–245.
  • Jeffery, P. K. 1998. Structural and inflammatory changes in COPD: A comparison with asthma. Thorax 53:129–136.
  • Kantengwa, S., Jornot, L., Devenoges, C., and Nicod, L. P.2003. Superoxide anions induce the maturation of human dendritic cells. Am. J. Respir. Crit. Care Med. 167:431–437.
  • Lavigne, M. C., and Eppihimer, M. J. 2005. Cigarette smoke condensate induces MMP-12 gene expression in airway-like epithelia. Biochem. Biophys. Res Commun 330:194–203.
  • Marwick, J.A., Kirkham, P.A., Stevenson, C.S., Danahay, H., Giddings, J., Butler, K., Donaldson, K., Macnee, W., Rahman, I. 2004. Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs. Am. J. Respir. Cell Mol. Biol. 2004;31:633–642.
  • Mishra, A., Chaudhary, A., and Sethi, S. 2004. Oxidized omega-3 fatty acids inhibit NF-kappaB activation via a PPAR-alpha-dependent pathway. Arteriosclerosis Thromb. Vasc. Biol. 24:1621–1627.
  • Morales, V., Giamarchi, C., Chailleux, C., Moro, F., Marsaud, V., Le Ricousse, S., Richard-Foy, H. 2001. Chromatin structure and dynamics: Functional implications. Biochimie 83:1029–1039.
  • Nishikawa, M., Kakemizu, N., Ito, T., Kudo, M., Kaneko, T., Suzuki, M., Udaka, N., Ikeda, H., Okubo, T. 1999. Superoxide mediates cigarette smoke-induced infiltration of neutrophils into the airways through nuclear factor κB activation and IL-8 mRNA expression in guinea pigs in vivo. Am. J. Respir. Cell Mol. Biol. 20:189–198.
  • Rahman, I. 2003. Oxidative stress, chromatin remodelling and gene transcription in inflammation and chronic lung disease. J. Biochem. Mol. Biol. 36:95–109.
  • Rahman, I., and MacNee, W. 1999. Lung glutathione and oxidative stress: implications in cigarette smoke-induced airways disease. Am. J. Physiol. Lung Cell Mol. Physiol. 227:1067–1088.
  • Saetta, M., Turato, G., Facchini, F.M., Corbino, L., Lucchini, R.E., Casoni, G., Maestrelli, P., Mapp, C.E., Ciaccia, A., Fabbri, L.M. 1997. Inflammatory cells in the bronchial glands of smokers with chronic bronchitis. Am. J. Respir. Crit. Care Med. 156:1633–1639.
  • Saetta, M., Di Stefano, A., Turato, G., Facchini, F.M., Corbino, L., Mapp, C.E., Maestrelli, P., Ciaccia, A., Fabbri, L.M. 1998. CD8+ t-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 157:822–826.
  • Shen, F., Zhao, M.-W., He, B., Pei, F., Yao, W.-Z. 2006. Observations on lung function and pathological changes of airway lung tissues in rats with different passive-smoking durations. J. GuiYang Med. Coll. 3:247–251 [in Chinese].
  • Schreck, R., Rieber, P., and Baeuerle, P. A. 1991. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. EMBO J. 10:2247–2258.
  • Smith, S.J., Fenwick, P.S., Nicholson, A.G., Kirschenbaum, F., Finney-Hayward, T.K., Higgins, L.S., Giembycz, M.A., Barnes, P.J., Donnelly, L.E. 2006. Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages. Br. J. Pharmacol. 149:393–404.
  • Srivastava, P. 2002. Interaction of heat shock proteins with peptides and antigen presenting cells: Chaperoning of the innate and adaptive immune responses. Annu. Rev. Immunol. 20:395–425.
  • Steer, J.H., Kroeger, K.M., Abraham, L.J., Joyce, D.A. 2000. Glucocorticoids suppress tumor necrosis factor-α expression by human monocytic THP-1 cells by suppressing transactivation through adjacent NF-κB and c-Jun-activating transcription factor-2 binding sites in the promoter. J. Biol. Chem. 275:18432–18440.
  • Szulakowski, P., Crowther, A.J., Jiménez, L.A., Donaldson, K., Mayer, R., Leonard, T.B., MacNee, W., Drost, E.M. 2006. The effect of smoking on the transcriptional regulation of lung inflammation in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 174:41–50.
  • Valenca, S.S., Castro, P., Pimenta, W.A., Lanzetti, M., Silva, S.V., Barja-Fidalgo, C., Koatz, V.L., Porto, L.C. 2006. Light cigarette smoke-induced emphysema and NF-κB activation in mouse lung. Int. J. Exp. Pathol. 87:373–381.
  • Vayssier, M., Banzet, N., François, D., Bellmann, K., Polla, B.S. 1998. Tobacco smoke induces both apoptosis and necrosis in mammalian cells: Differential effects of HSP70. Am. J. Physiol. 275:L771–L779.
  • Vernooy, J.H., Dentener, M.A., van Suylen, R.J., Buurman, W.A., Wouters, E.F 2002. Long-term intratracheal lipopolysaccharide exposure in mice results in chronic lung inflammation and persistent pathology. Am. J. Respir. Cell Mol. Biol. 26:152–159.
  • Yamamoto, K., Takanashi, S., Hasegawa, Y., Kanehira, Y., Kaizuka, M., Okumura, K. 2003. Eotaxin level in induced sputum is increased in patients with bronchial asthma and in smokers. Respiration 70:600–605.
  • Grunstein, M. 1997. Histone acetylation in chromatin structure and transcription. Nature 389:349–352.

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