Thioredoxin Mediates Remodeling Factors of Human Bronchial Epithelial Cells upon Interaction with House Dust Mite-Stimulated Eosinophils

References

• E. Adam, K. K. Hansen, O. Astudillo Fernandez, L. Coulon, F. Bex, X. Duhant, E. Jaumotte, M. D. Hollenberg, and A. Jacquet. 2006. The house dust mite allergen Der p1, unlike Der p3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism. J. Biol. Chem. 281:6910–6923.
   PubMed Web of Science ®Google Scholar
• A. A. Andreadis, S. L. Hazen, S. A. Comhair, and S. C. Erzurum. 2003. Oxidative and nitrosative events in asthma. Free Radic. Biol. Med. 35:213–225.
   PubMed Web of Science ®Google Scholar
• E. S. Arner, and A. Holmgren. 2000. Physiological functions of thioredoxin and thioredoxin reductase. Eur. J. Biochem. 267:6102–6109.
   PubMedGoogle Scholar
• R. Beasley. 2002. The burden of asthma with specific reference to the United States. J. Allergy Clin. Immunol. 109:S482–S489.
   PubMed Web of Science ®Google Scholar
• T. Bellido, C. A. O'Brien, P. K. Roberson, and S. C. Manolagas. 1998. Transcriptional activation of the p21(WAF1, CIP1, SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells. J. Biol. Chem. 273:21137–21144.
   PubMed Web of Science ®Google Scholar
• N. Berkova, S. Lair-Fulleringer, F. Féménia, D. Huet, M. C. Wagner, K. Gorna, F. Tournier, O. Ibrahim-Granet, J. Guillot, R. Chermette, P. Boireau, and J. P. Latgé. 2006. Aspergillus fumigatus conidia inhibit tumor necrosis factor- or staurosporine-induced apoptosis in epithelial cells. Int. Immunol. 18:139–150.
   PubMed Web of Science ®Google Scholar
• G. C. Blobe, W. P. Schiemann, and H. F. Lodish. 2000. Role of transforming growth factor-β in human disease. New Engl. J. Med. 342:1350–1358.
   PubMed Web of Science ®Google Scholar
• P. F. Bove, U. V. Wesley, A. K. Greul, M. Hristova, W. R. Dostmann, and A. van der Vliet. 2007. Nitric oxide promotes airway epithelial wound repair through enhanced activation of MMP-9. Am. J. Respir. Cell Mol. Biol. 36:138–146.
   PubMed Web of Science ®Google Scholar
• A. Burke-Gaffney, M. E. Callister, and H. Nakamura. 2005. Thioredoxin: Friend or foe in human disease?. Trends Pharmacol. Sci. 26:398–404.
   PubMed Web of Science ®Google Scholar
• W. W. Busse, and L. J. Rosenwasser. 2003. Mechanisms of asthma. J. Allergy Clin. Immunol. 111:S799–S804.
   PubMed Web of Science ®Google Scholar
• M. D. Chapman, S. Wunschmann, and A. Pomes. 2007. Proteases as Th2 adjuvants. Curr. Allergy Asthma Rep. 7:363–367.
   PubMed Web of Science ®Google Scholar
• L. Cohn, J. A. Elias, and G. L. Chupp. 2004. Asthma: Mechanisms of disease persistence and progression. Annu. Rev. Immunol. 22:789–815.
   PubMed Web of Science ®Google Scholar
• W. R. Coward, H. Sagara, S. J. Wilson, S. T. Holgate, and M. K. Church. 2004. Allergen activates peripheral blood eosinophil nuclear factor-κ B to generate granulocyte macrophage-colony stimulating factor, tumor necrosis factor-α, and interleukin-8. Clin. Exp. Allergy 34:1071–1078.
   PubMedGoogle Scholar
• R. Dworski. 2002. Oxidant stress in asthma. Thorax 55:S51–53.
   Google Scholar
• T. C. Fan, H. T. Chang, I. W. Chen, H. Y. Wang, and M. D. Chang. 2007. A heparan sulfate-facilitated and raft-dependent macropinocytosis of eosinophil cationic protein. Traffic 8:778–1795.
   Google Scholar
• I. A. Fedorov, S. J. Wilson, D. E. Davies, and S. T. Holgate. 2005. Epithelial stress and structural remodeling in childhood asthma. Thorax 60:389–394.
   PubMed Web of Science ®Google Scholar
• A. L. Gartel, and A. L. Tyner. 2002. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol. Cancer Ther. 1:639–649.
   PubMed Web of Science ®Google Scholar
• M. A. Giembycz, and M. A. Lindsay. 1999. Pharmacology of the eosinophil. Pharmacol. Rev. 51:213–340.
   PubMed Web of Science ®Google Scholar
• I. Gomes, S. K. Mathur, B. M. Espenshade, Y. Mori, J. Varga, and S. J. Ackerman. 2005. Eosinophil-fibroblast interactions induce fibroblast IL-6 secretion and extracellular matrix gene expression: Implications in fibrogenesis. J. Allergy Clin. Immunol. 116:796–804.
   PubMedGoogle Scholar
• L. M. Hamilton, C. Torres-Lozano, S. M. Puddicombe, A. Richter, I. Kimber, R. J. Dearman, B. Vrugt, R. Aalbers, S. T. Holgate, R. Djukanović, S. J. Wilson, and D. E. Davies. 2003. The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma. Clin. Exp. Allergy 33:233–240.
   PubMed Web of Science ®Google Scholar
• J. M. Hansen, Y. M. Go, and D. P. Jones. 2006. Nuclear and mitochondrial compartmentation of oxidative stress and redox signaling. Annu. Rev. Pharmacol. Toxicol. 46:215–234.
   PubMed Web of Science ®Google Scholar
• Y. Hiraguchi, M. Nagao, K. Hosoki, R. Tokuda, and T. Fujisawa. 2008. Neutrophil proteases activate eosinophil function in vitro. Int. Arch. Allergy Immunol. 46 (Suppl. 1):16–21.
   Google Scholar
• M. Hoshino, Y. Nakamura, and J. J. Sim. 1998. Expression of growth factors and remodeling of the airway wall in bronchial asthma. Thorax 53:21–27.
   PubMed Web of Science ®Google Scholar
• H. Ichiki, T. Hoshino, T. Kinoshita, H. Imaoka, S. Kato, H. Inoue, H. Nakamura, J. Yodoi, H. A. Young, and H. Aizawa. 2005. Thioredoxin suppresses airway hyperresponsiveness and airway inflammation in asthma. Biochem. Biophys. Res. Commun. 334:1141–1148.
   PubMed Web of Science ®Google Scholar
• H. Imaoka, T. Hoshino, S. Takei, Y. Sakazaki, T. Kinoshita, M. Okamoto, T. Kawayama, J. Yodoi, S. Kato, T. Iwanaga, and H. Aizawa. 2007. Effects of thioredoxin on established airway remodeling in a chronic antigen exposure asthma model. Biochem. Biophys. Res. Commun. 360:525–530.
   PubMedGoogle Scholar
• A. L. James, P. D. Pare, and J. C. Hogg. 1989. The mechanics of airway narrowing in asthma. Am. Rev. Respir. Dis. 139:242–246.
   PubMed Web of Science ®Google Scholar
• M. Kaimul Ahsan, H. Nakamura, M. Tanito, K. Yamada, H. Utsumi, and J. Yodoi. 2005. Thioredoxin-1 suppresses lung injury and apoptosis induced by diesel exhaust particles (DEP) by scavenging reactive oxygen species and by inhibiting DEP-induced down-regulation of Akt. Free Radic. Biol. Med. 39:1549–1559.
   PubMed Web of Science ®Google Scholar
• N. A. Kalsheker, S. Deam, L. Chambers, S. Sreedharan, K. Brocklehurst, and D. A. Lomas. 1996. The house dust mite allergen Der p1 catalytically inactivates α 1-antitrypsin by specific reactive centre loop cleavage: A mechanism that promotes airway inflammation and asthma. Biochem. Biophys. Res. Commun. 221:59–61.
   PubMedGoogle Scholar
• C. King, S. Brennan, P. J. Thompson, and G. A. Stewart. 1998. Dust mite proteolytic allergens induce cytokine release from cultured airway epithelium. J. Immunol. 161:3645–3651.
   PubMed Web of Science ®Google Scholar
• J. Massagué. 2000. How cells read TGF-beta signals. Nat. Rev. Mol. Cell Biol. 1:169–178.
   PubMed Web of Science ®Google Scholar
• H. Masutani, S. Ueda, and J. Yodoi. 2005. The thioredoxin system in retroviral infection and apoptosis. Cell Death Differ. 12:991–998.
   PubMedGoogle Scholar
• S. Miike, and H. Kita. 2003. Human eosinophils are activated by cysteine proteases and release inflammatory mediators. J. Allergy Clin. Immunol. 111:704–713.
   PubMed Web of Science ®Google Scholar
• E. M. Minshall, D. Y. Leung, R. J. Martin, Y. L. Song, L. Cameron, P. Ernst, and Q. Hamid. 1997. Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma. Am. J. Respir. Cell Mol. Biol. 17:326–333.
   PubMed Web of Science ®Google Scholar
• M. M. Murillo, G. del Castillo, A. Sánchez, M. Fernández, and I. Fabregat. 2005. Involvement of EGF receptor and c-Src in the survival signals induced by TGF-β 1 in hepatocytes. Oncogene 24:4580–4587.
   PubMed Web of Science ®Google Scholar
• H. Ohbayashi, and K. Shimokata. 2005. Matrix metalloproteinase-9 and airway remodeling in asthma. Curr. Drug Targets Inflamm. Allergy 4:177–181.
   PubMedGoogle Scholar
• R. M. Pascual, and S. P. Peters. 2005. Airway remodeling contributes to the progressive loss of lung function in asthma: An overview. J. Allergy Clin. Immunol. 116:477–486.
   PubMed Web of Science ®Google Scholar
• S. Pegorier, L. A. Wagner, G. J. Gleich, and M. Pretolani. 2006. Eosinophil-derived cationic proteins activate the synthesis of remodeling factors by airway epithelial cells. J. Immunol. 177:4861–4869.
   PubMed Web of Science ®Google Scholar
• I. Rahman, S. K. Biswas, and A. Kode. 2006. Oxidant and antioxidant balance in the airways and airway diseases. Eur. J. Pharmacol. 533:222–239.
   PubMed Web of Science ®Google Scholar
• A. E. Redington, D. R. Springall, Q. H. Meng, A. B. Tuck, S. T. Holgate, J. M. Polak, and P. H. Howarth. 1997. Immunoreactive endothelin in bronchial biopsy specimens: Increased expression in asthma and modulation by corticosteroid therapy. J. Allergy Clin. Immunol. 100:544–552.
   PubMed Web of Science ®Google Scholar
• S. I. Rennard. 1996. Repair mechanisms in asthma. J. Allergy Clin. Immunol. 98:S278–S286.
   PubMed Web of Science ®Google Scholar
• M. E. Rothenberg, and S. P. Hogan. 2006. The eosinophil. Annu. Rev. Immunol. 24:147–174.
   PubMed Web of Science ®Google Scholar
• S. P. Sanders, J. L. Zweier, S. J. Harrison, M. A. Trush, S. J. Rembish, and M. C. Liu. 1995. Spontaneous oxygen radical production at sites of antigen challenge in allergic subjects. Am. J. Respir. Crit. Care Med. 151:1725–1733.
   PubMed Web of Science ®Google Scholar
• A. Sato, T. Hara, H. Nakamura, N. Kato, Y. Hoshino, N. Kondo, M. Mishima, and J. Yodoi. 2006. Thioredoxin-1 suppresses systemic inflammatory responses against cigarette smoking. Antioxid. Redox Signal. 8:1891–1896.
   PubMed Web of Science ®Google Scholar
• Y. Seomun, J. T. Kim, and C. K. Joo. 2008. MMP-14 mediated MMP-9 expression is involved in TGF-beta1-induced keratinocyte migration. J. Cell. Biochem. 104:934–941.
   PubMed Web of Science ®Google Scholar
• G. Sheng, K. Q. Bernabe, J. Guo, and B. W. Warner. 2006. Epidermal growth factor receptor-mediated proliferation of enterocytes requires p21waf1/cip1 expression. Gastroenterology 131:153–164.
   PubMed Web of Science ®Google Scholar
• A. Slungaard, G. M. Vercellotti, G. Walker, R. D. Nelson, and H. S. Jacob. 1990. Tumor necrosis factor-α /cachectin stimulates eosinophil oxidant production and toxicity towards human endothelium. J. Exp. Med. 171:2025–2041.
   PubMed Web of Science ®Google Scholar
• M. A. Stacey, G. Sun, G. Vassalli, M. Marini, A. Bellini, and S. Mattoli. 1997. The allergen Der p1 induces NF-κ B activation through interference with Iκ Bα function in asthmatic bronchial epithelial cells. Biochem. Biophys. Res. Commun. 236:522–526.
   PubMedGoogle Scholar
• L. Svensson, A. Rudin, and C. Wenneras. 2004. Allergen extracts directly mobilize and activate human eosinophils. Eur. J. Immunol. 34:1744–1751.
   PubMedGoogle Scholar
• A. Trautmann, P. Schmid-Grendelmeier, K. Krüger, R. Crameri, M. Akdis, A. Akkaya, E. B. Bröcker, K. Blaser, and C. A. Akdis. 2002. T-Cells and eosinophils cooperate in the induction of bronchial epithelial cell apoptosis in asthma. J. Allergy. Clin. Immunol. 109:329–337.
   PubMed Web of Science ®Google Scholar
• M. Ueno, H. Masutani, R. J. Arai, A. Yamauchi, K. Hirota, T. Sakai, T. Inamoto, Y. Yamaoka, J. Yodoi, and T. Nikaido. 1999. Thioredoxin-dependent redox regulation of p53-mediated p21 activation. J. Biol. Chem. 274:35809–35815.
   PubMed Web of Science ®Google Scholar
• A. M. Vignola, P. Chanez, G. Chiappara, A. Merendino, E. Pace, A. Rizzo, A. M. la Rocca, V. Bellia, G. Bonsignore, and J. Bousquet. 1997. Transforming growth factor-β expression in mucosal biopsies in asthma and chronic bronchitis. Am. J. Respir. Crit. Care. Med. 156:591–599.
   PubMed Web of Science ®Google Scholar
• A. B. Vroling, D. Duinsbergen, W. J. Fokkens, and C. M. van Drunen. 2007. Allergen induced gene expression of airway epithelial cells shows a possible role for TNF-alpha. Allergy 62:1310–1319.
   PubMedGoogle Scholar
• G. M. Walsh. 2001. Eosinophil-epithelial cell interactions: A special relationship?. Clin. Exp. Allergy 31:351–354.
   PubMedGoogle Scholar
• H. Wan, H. L. Winton, C. Soeller, G. W. Taylor, D. C. Gruenert, P. J. Thompson, M. B. Cannell, G. A. Stewart, D. R. Garrod, and C. Robinson. 2001. The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from fecal pellets of Dermatophagoides pteronyssinus. Clin. Exp. Allergy 31:279–294.
   PubMed Web of Science ®Google Scholar
• K. Wakahara, H. Tanaka, G. Takahashi, M. Tamari, R. Nasu, T. Toyohara, H. Takano, S. Saito, N. Inagaki, K. Shimokata, and H. Nagai. 2008. Repeated instillations of Dermatophagoides farinae into the airways can induce Th2-dependent airway hyperresponsiveness, eosinophilia and remodeling in mice: effect of intratracheal treatment of fluticasone propionate. Eur. J. Pharmacol. 578:87–96.
   PubMed Web of Science ®Google Scholar
• A. J. Wardlaw, C. E. Brightling, R. Green, G. Woltmann, P. Bradding, and I. D. Pavord. 2002. New insights into the relationship between airway inflammation and asthma. Clin. Sci. 103:201–211.
   PubMed Web of Science ®Google Scholar
• C. K. Wong, C. Y. Ho, F. W. Ko, C. H. Chan, A. S. Ho, D. S. Hui, and C. W. Lam. 2001. Pro-inflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and TH cytokines (IFNγ, IL-4, IL-10, and IL-13) in patients with allergic asthma. Clin. Exp. Immunol. 125:177–183.
   PubMed Web of Science ®Google Scholar
• C. K. Wong, M. L. Li, C. B. Wang, W. K. Ip, Y. P. Tian, and C. W. Lam. 2006. House dust mite allergen Der p1 elevates the release of inflammatory cytokines and expression of adhesion molecules in co-culture of human eosinophils and bronchial epithelial cells. Int. Immunol. 18:1327–1335.
   PubMedGoogle Scholar
• T. Yamada, Y. Iwasaki, K. Nagata, S. Fushiki, H. Nakamura, Y. Marunaka, and J. Yodoi. 2007. Thioredoxin-1 protects against hyperoxia-induced apoptosis in cells of the alveolar walls. Pulm. Pharmacol. Ther. 20:650–659.
   PubMed Web of Science ®Google Scholar
• M. Yamasaki, H. R. Kang, R. J. Homer, S. P. Chapoval, S. J. Cho, B. J. Lee, J. A. Elias, and C. G. Lee. 2008. P21 regulates TGF-β 1-induced pulmonary responses via a TNFα -signaling pathway. Am. J. Respir. Cell Mol. Biol. 38:346–353.
   PubMed Web of Science ®Google Scholar
• K. Yamauchi, and H. Inoue. 2007. Airway remodeling in asthma and irreversible airflow limitation-ECM deposition in airway and possible therapy for remodeling. Allergol. Int. 56:321–329.
   PubMedGoogle Scholar
• H. K. Yoon, H. Y. Cho, and S. R. Kleeberger. 2007. Protective role of matrix metalloproteinase-9 in ozone-induced airway inflammation. Environ. Health Persp. 115:1557–1563.
   PubMed Web of Science ®Google Scholar
• S. Yoshida, T. Katoh, T. Tetsuka, K. Uno, N. Matsui, and T. Okamoto. 1999. Involvement of thioredoxin in rheumatoid arthritis: Its co-stimulatory roles in the TNFα -induced production of IL-6 and IL-8 from cultured synovial fibroblasts. J. Immunol. 163:351–358.
   PubMed Web of Science ®Google Scholar