Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 21, 2009 - Issue 3
102
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Influence of ALDH2 Polymorphism on Ethanol Kinetics and Pulmonary Effects in Male and Female Rats Exposed to Ethanol Vapors

, &
Pages 193-199 | Received 20 May 2008, Accepted 27 Jul 2008, Published online: 01 Feb 2009

REFERENCES

  • E. M. Carvalho, G. A. C. Brito, B. B. G. P. Pessoa, R. A. Ribeiro, and F. R. Capaz. (2005). Long-term ethanol intoxication reduces inflammatory responses in rats. Braz. J. Med. Biol. Res. 38:81–89.
  • I. Chu, R. Poon, V. Valli, A. Yagminas, W. J. Bowers, R. Seegal, and R. Vincent. (2005). Effects of an ethanol-gasoline mixture: Results of a 4-week inhalation study in rats. J. Appl. Toxicol. 25:193–199.
  • G. Del Zoppo. (2003). Aldehyde dehydrogenase (ALDH2) polymorphism and the pulmonary effects associated with exposure to ethanol vapors in the rat. Master's Thesis, Institut National de Recherche Scientifique (INRS) – Institut Armand-Frappier 531 boul. des Prairies Laval (Québec), Canada.
  • Health Canada. (2005). Gasoline with ethanol: A green alternative. Available at http://oee.nrcan.gc.ca/Publications/transportation/ethanol-awareness.cfm?Text=N&PrintView=N (accessed December 2005).
  • C. S. Lieber. (2000). Ethnic and gender differences in ethanol metabolism. Alcohol. Clin. Exp. Res. 24:417–418.
  • H. R. Luo, and Y. P. Zhang. (2004). Aldehyde dehydrogenase (ALDH2) polymorphism and drinking behavior. Yi Chuan. 26:263–266.
  • C. A. Marietta, T. R. Jerrels, R. C. Meagher, J. W. Karanian, F. F. Weoght, and M. J. Eckardt. (1988). Effects of long-term inhalation on the immune and hematopoietic systems of the rat. Alcohol. Clin. Exp. Res. 12:211–214.
  • J. E. Manautou, and G. P. Carlson. (1992). Comparison of rat pulmonary and hepatic cytosolic alcohol dehydrogenase activities. J. Toxicol. Environ. Health. 35:7–18.
  • M. C. McElroy, A. D. Postle, and F. J. Kelly. (1992). Catalase, superoxidase dismutase and glutathione peroxidase activities of lung and liver during human development. Biochim. Biophys. Acta. 1117:153–158.
  • T. Oyama, T. Isse, N. Kagawa, T. Kinaga, Y. D. Kim, M. Morita, K. Sugio, H. Weiner, K. Yasumoto, and T. Kawamoto. (2005). Tissue-distribution of aldehyde dehydrogenase 2 and effects of the ALDH2 gene-disruption on the expression of enzymes involved in alcohol metabolism. Front. Biosci. 10:951–960.
  • A. Parkinson. (2001). Biotransformation of xenobiotics. In Casarett and Doull's toxicology. The basic science of poisons, ed. C. D. Klaassen. 6th ed., pp. 152–156. New York: McGraw-Hill.
  • G. M. Pastino, B. Asgharian, K. Roberts, M. A. Medinsky, and J. Bond. (1997). A comparison of physiologically based pharmacokinetic model predictions and experimental data for inhaled ethanol in male and female B6C3F1 mice, F344 rats, and humans. Toxicol. Appl. Pharmacol. 145:147–157.
  • J. C. Rowlands, L. He, and T. M. Badger. (2003). Glucose inhibition of the induction of CYP2E1 mRNA expression by ethanol in FGC-4 cells. Xenobiotica 33:389–397.
  • H. K. Seitz, G. Egerer, U. A. Simanowski, R. Waldherr, R. Eckey, D. P. Agarwal, H. W. Goedde, and J. P. von Wartburg. (1993). Human gastric alcohol dehydrogenase activity: Effect of age, sex, and alcoholism. Gut 34:1433–1437.
  • G. Szabo. (1999). Consequences of alcohol consumption on host defence. Alcohol alcohol. 34:830–841.
  • A. Takao, T. Shimoda, S. Kohno, S. Asai, and S. Harda. (1998). Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype. J. Allergy Clin. Immunol. 101:576–580.
  • R. Tardif, and M. Charbonneau. (2001). Caractérisation de la toxicocinétique de l'acétaldéhyde et de l'éthanol après inhalation de vapeurs d'éthanol chez le rat. TSRI Project #318. Final Report, Toxic Substances Research Initiative, Government of Canada, Ottawa, Canada.
  • U.S. EPA. (1994). Methods for Derivation of Inhalation Reference Concentrations and Application of Inhalation Dosimetry. Office of Research and Development, Washington, DC. EPA/600/8-90/066F. Available on-line at http://www.epa.gov/cgi-bin/claritgw?op-Display&document=clserv:ORD:0327;&rank=4&template=epa.
  • M. Yamauchi, Y. Maezawa, S. Satoh, Y. Mizuhara, and G. Toda. (1996). Genetic polymorphism of the rat aldehyde dehydrogenase 2 and the severity of experimental alcohol-induced lover damage. Int. Hepatol. Comm. 5:143–149.
  • M. Yang, B. F. Coles, R. Delongchamp, N. P. Lang, and F. F. Kadlubar. (2002). Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphism on their expressions in Caucasian lung tissue. Lung Cancer 38:15–21.
  • A. Zerilli, D. Lucas, Y. Amet, F. Beauge, A. Volant, H. H. Floch, F. Berthou, and J. F. Menez. (1995). Cytochrome P-450 2E1 in rat liver, kidney and lung microsomes after chronic administration of ethanol either orally or by inhalation. Alcohol Alcohol. 30:357–365.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.