Genotoxicity Versus Carcinogenicity: Implications from Fiber Toxicity Studies

References

• Aust, A. E. 1994. The role of iron in asbestos induced cancer. In Cellular and molecular effects of mineral and synthetic dusts and fibers, eds. J. M. G. Davis and M. Jaurand, pp. 53–61. Heidelberg: Springer-Verlag.
   Google Scholar
• Both, K., Henderson, D. W., and Turner, D. R. 1994. Asbestos and erionite fibers can induce mutations in human lymphocytes that resulted in loss of heterozygosity. Int. J. Cancer 59:538–542.
   Google Scholar
• Brown, R. C., Poole, A., and Fleming, G. T. A. 1983. The influence of asbestos dust on the oncogenic transformation of C3H10T1/2 cells. Cancer Lett. 18:221–225.
   Google Scholar
• Ellouk, S. A., and laurand, M. 1994. Review of animal/in vitro data on biological effects of man-made fibers. Environ. Health Perspect. 102:47–61.
   Google Scholar
• Hart, G. A., Kathman, L. M., and Hesterberg, T. W. 1994. In vitro cytotoxicity of asbestos and man-made vitreous fibers. Carcinogenesis 15:971–977.
   Google Scholar
• Hei, T. K., Hall, E.J., and Osmak, R. S. 1984. Asbestos, radiation and oncogenic transformation. Br. J. Cancer 50:717–720.
   Google Scholar
• Hei, T. K., He, Z. Y., Piao, C. Q., and Waldren, C. A. 1991. The mutagenicity of mineral fibers. In Mechanisms in fiber carcinogenesis, eds. R. C. Brown, J. A. Hoskins, and N. F. Johnson, pp. 319–325. New York: Plenum.
   Google Scholar
• Hei, T. K., Piao, C. Q., He, Z. Y., Vannais, D., and Waldren, C. A. 1992. Chrysotile fiber is a potent mutagen in mammalian cells. Cancer Res. 52:6305–6309.
   Google Scholar
• Hei, T. K., Piao, C. Q., Sutter, T., Willey, J. C., and Suzuki, K. 1996. Cellular and molecular alterations in human epithelial cells transformed by high LET radiation. Adv. Space Res. 18:137–148.
   Google Scholar
• Hei, T. K., Wu, L. J., and Piao, C. Q. 1997. Malignant transformation of immortalized human bronchial epithelial cells by asbestos fibers. Environ. Health Perspect. 105:1085–1088.
   Google Scholar
• Hesterberg, T. W., Butterick, C. J., Oshimura, M., Brody, A. R., and Barrett, J. C. 1986. Role of phagocytosis in Syrian hamster cell transformation and cytogenetic effects induced by asbestos and short and long glass fibers. Cancer Res. 46:5795–5802.
   Google Scholar
• Howden, P. J., and Faux, S. P. 1996. Glutathione modulates the formation of 8-OHdG in isolated DNA and mutagenicity in Salmonella typhimurium TA 100 induced by mineral fibers. Carcinogenesis 17:2275–2277.
   Google Scholar
• Jaurand, M. C. 1996. Use of in-vitro genotoxicity and cell transformation assays to evaluate the potential carcinogenicity of fibers. In Mechanisms of fiber carcinogenesis, eds. A. B. Kane, P. Boffetta, R. Saracci, and J. D. Wilbourn, pp. 55–72. Lyon: IARC.
   Google Scholar
• Jaurand, M. C., Yeagles, M., Dong, H. Y., Renier, A., St. Etienne, L., Kheuang, L., Janson, X., and Bignon, J. 1994. In vitro DNA and chromosomal damage produced by some minerals and man-made particles on rat pleural mesothelial cells. In Cellular and molecular effects of mineral and synthetic dusts and fibers, eds. J. M. G. Davis and M. Jaurand, pp. 183–192. Heidelberg: Springer-Verlag.
   Google Scholar
• Kamp, D. W., Graceffa, P., Prylor, W. A., and Weitzman, S. A. 1992. The role of free radicals in asbestos induced diseases. Free Radical Biol. Med. 12:293–315.
   Google Scholar
• Kuschner, M., and Wright, G. W. 1976. The effects of intratracheal instillation of glass fiber of varying size in guinea pigs. Proc. NIOSH Conf. Occupational Exposure of Fibrous Glass, College Park, MD, pp. 151–168.
   Google Scholar
• Lezon-Geyda, K., Jaime, C. M., Godbold, J. H., Savransky, E. F., Hope, A., Kheiri, S. A., Dzmura, Z. M., Uehara, H., Johnson, E. M., and Fasy, T. M. 1996. Chrysotile asbestos fibers mediate homologous recombination in Rat2λ fibroblasts: Implications for carcinogenesis. Mutat. Res. 361:113–120.
   Google Scholar
• Miller, K., Handfield, R., and Kagan, E. 1978. The effect of different mineral dusts on the mechanism of phagocytosis. Environ. Res. 15:139–154.
   Google Scholar
• Namba, M., Mihara, K., and Fushimi, K. 1996. Immortalization of human cells and its mechanisms. Crit. Rev. Oncogen. 7:19–31.
   Google Scholar
• Okayasu, R., Wu, L., and Hei, T. K. 1999. Biological effects of naturally-occurring and man-made fibers: In vitro cytotoxicity and mutagenesis in mammalian cells. Br. J. Cancer 79:1319–1324.
   Google Scholar
• Park, S. H., and Aust, A. E. 1998. Participation of iron and nitric oxide in the mutagenicity of asbestos in hgprt-, gpt+ Chinese hamster V79 cells. Cancer Res. 58:1144–1148.
   Google Scholar
• Renan, M. J. 1993. How many mutations are required for tumorigenesis. Implications for human cancer data. Mol. Carcinogen. 7:139–146.
   Google Scholar
• Xu, A., Wu, L. J., Santella, R. M., and Hei, T. K. 1999a. Role of oxyradicals in mutagenicity and DNA damage induced by crocidolite asbestos in mammalian cells. Cancer Res. 59:5922–5926.
   Google Scholar
• Xu, L., Flynn, B. J., Ungar, S., Pass, H. L., Linnainmaa, K., Mattson, K., and Gerwin, B. I. 1999b. Asbestos induction of extended lifespan in normal mesothelial cells: Inter-individual susceptibility and SV40 T-antigen. Carcinogenesis 20:773–783.
   Google Scholar