Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 31, 2019 - Issue 1
363
Views
3
CrossRef citations to date
0
Altmetric
Review Article

A review of the fate of inhaled α-quartz in the lungs of rats

Pages 25-34 | Received 18 Oct 2018, Accepted 08 Mar 2019, Published online: 18 Apr 2019

References

  • Adamson IY. (1992). Radiation enhances silica translocation to the pulmonary interstitium and increases fibrosis in mice. Environ Health Perspect 97:233–8.
  • Adamson IY, Prieditis H, Bowden DH. (1992). Instillation of chemotactic factor to silica-injected lungs lowers interstitial particle content and reduces pulmonary fibrosis. Am J Pathol 141:319–26.
  • Adamson IY, Prieditis H, Bowden DH. (1994). Enhanced clearance of silica from mouse lung after instillation of a leukocyte chemotactic factor. Exp Lung Res 20:223–33.
  • Ajuebor M, Flower R, Hannon R, et al. (1998). Endogenous monocyte chemoattractant protein-1 recruits monocytes in zymosan peritonitis model. J Leukocyte Biol 63:108–16.
  • Arts JH, Muijser H, Duistermaat E, et al. (2007). Five-day inhalation toxicity study of three types of synthetic amorphous silicas in Wistar rats and post-exposure evaluations for up to 3 months. Food Chem Toxicol 45:1856–67.
  • Barrett EG, Johnston C, Oberdörster G, et al. (1999). Silica-induced chemokine expression in alveolar type II cells is mediated by TNF-α-induced oxidant stress. Am J Physiol 276:L979–88.
  • Bellmann B, Muhle H, Creutzenberg O, et al. (1991). Lung clearance and retention of toner, utilizing a tracer technique, during chronic inhalation exposure in rats. Fundam Appl Toxicol 17:300–13.
  • Bermudez E, Mangum J, Asgharian B, et al. (2002). Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles. Toxicol Sci 70:86–97.
  • Bice DE, Hahn FF, Benson J, et al. (1987). Comparative lung immunotoxicity of inhaled quartz and coal combustion fly ash. Environ Res 43:374–89.
  • Bienenstock J, McDermott M. (2005). Bronchus- and nasal-associated lymphoid tissues. Immunol Rev 206:22–31.
  • Bowden D. (1984). The alveolar macrophage. Environ Health Perspect 55:327–41.
  • Brody AR, Roe MW, Evans JN, et al. (1982). Deposition and translocation of inhaled silica in rats. Quantification of particle distribution, macrophage participation, and function. Lab Invest 47:533–42.
  • Brown GM, Brown DM, Donaldson K. (1992). Persistent inflammation and impaired chemotaxis of alveolar macrophages on cessation of dust exposure. Environ Health Perspect 97:91–4.
  • Brundelet JM. (1965). Experimental study of the dust-clearance mechanims of the lung. I. Histological study in rats of the intra-pulmonary bronchial route of elimination. Acta Pathol Microbiol Scand Suppl 175:1–141.
  • Burns CA, Zarkower A, Ferguson FG. (1980). Murine immunological and histological changes in response to chronic silica exposure. Environ Res 21:298–307.
  • Castranova V, Vallyathan V. (2000). Silicosis and coal workers' pneumoconiosis. Environ Health Perspect 108 Suppl 4:675–84.
  • Castranova V, Porter D, Millecchia L, et al. (2002). Effect of inhaled crystalline silica in a rat model: time course of pulmonary reactions. Mol Cell Biochem 234/235:177–84.
  • Cesta M. (2006). Normal structure, function, and histology of mucosa-associated lymphoid tissue. Toxicol Pathol 34:599–608.
  • Chong S, Lee KS, Chung MJ, et al. (2006). Pneumoconiosis: comparison of imaging and pathologic findings. Radiographics 26:59–77.
  • Cullen R, Tran C, Buchanan D, et al. (2000). Inhalation of poorly soluble particles. I. Differences in inflammatory response and clearance during exposure. Inhal Toxicol 12:1089–111.
  • Davis GS, Hemenway DR, Evans JN, et al. (1981). Alveolar macrophage stimulation and population changes in silica-exposed rats. Chest 80:8–10.
  • Davis GS. (1986). Pathogenesis of silicosis: current concepts and hypotheses. Lung 164:139–54.
  • Deshmane S, Kremlev S, Amini S, et al. (2009). Monocyte chemoattractant protein-1 (MCP-1): an overview. J Interferon Cytokine Res 29:313–26.
  • Ding M, Chen F, Shi X, et al. (2002). Diseases caused by silica: mechanisms of injury and disease development. Int Immunopharmacol 2:173–82.
  • Donaldson K, Bolton RE, Jones AD, et al. (1988). Kinetics of the bronchoalveolar leukocyte response in rats during exposure to equal airborne mass concentration of quartz, chrysotile asbestos or titanium dioxide. Thorax 43:159–62.
  • Donaldson K, Brown GM, Brown DM, et al. (1990a). Contrasting bronchoalveolar leukocyte responses in rats inhaling coal mine dust, quartz, or titanium dioxide: effects of coal rank, airborne mass concentration, and cessation of exposure. Environ Res 52:62–76.
  • Donaldson K, Brown GM, Brown DM, et al. (1990b). Impaired chemotactic responses of bronchoalveolar leukocytes in experimental pneumoconiosis. J Pathol 160:63–9.
  • Driscoll KE, Lindenschmidt RC, Maurer JK, et al. (1991). Pulmonary response to inhaled silica or titanium dioxide. Toxicol Appl Pharmacol 111:201–10.
  • Ferin J, Oberdörster G. (1992). Translocation of particles from pulmonary alveoli into the interstitium. J Aerosol Med 5:179–87.
  • Ferin J, Oberdörster G, Penney DP. (1992). Pulmonary retention of ultrafine and fine particles in rats. Am J Respir Cell Mol Biol 6:535–42.
  • Heine H, Rietschel ET, Ulmer AJ. (2001). The biology of endotoxin. Mol Biotechnol 19:279–96.
  • Hemenway DR, Absher MP, Trombley L, et al. (1990). Comparative clearance of quartz and cristobalite from the lung. Am Ind Hyg Assoc J 51:363–9.
  • Henderson RF, Driscoll KE, Harkema JR, et al. (1995). A comparison of the inflammatory response of the lung to inhaled versus instilled particles in F344 rats. Fundam Appl Toxicol 24:183–97.
  • Huang SH, Hubbs AF, Stanley CF, et al. (2001). Immunoglobulin responses to experimental silicosis. Toxicol Sci 59:108–17.
  • Katsnelson BA, Konyscheva LK, Sharapova NYe, et al. (1994). Prediction of the comparative intensity of pneumoconiotic changes caused by chronic inhalation exposure to dusts of different cytotoxicity by means of a mathematical model. Occup Environ Med 51:173–80.
  • Kawasaki H. (2015). A mechanistic review of silica-induced inhalation toxicity. Inhal Toxicol 27:363–77.
  • Kawasaki H. (2017). A mechanistic review of particle overload by titanium dioxide. Inhal Toxicol 29:530–40.
  • Kuper CF. (2006). Histopathology of mucosa-associated lymphoid tissue. Toxicol Pathol 34:609–15.
  • Kühlmann UC, Chwieralski CE, van den Brule S, et al. (2009). Modulation of cytokine production and silica-induced lung fibrosis by inhibitors of aminopeptidase N and of dipeptidyl peptidase-IV-related proteases. Life Sci 84:1–11.
  • Lauweryns JM, Baert JH. (1977). Alveolar clearance and the role of the pulmonary lymphatics. Am Rev Respir Dis 115:625–83.
  • Lee K, Trochimowicz H, Reinhardt C. (1985). Pulmonary response of rats exposed to titanium dioxide (TiO2) by inhalation for two years. Toxicol Appl Pharmacol 79:179–92.
  • Lee KP, Kelly DP. (1993). Translocation of particle-laden alveolar macrophages and intra-alveolar granuloma formation in rats exposed to Ludox colloidal amorphous silica by inhalation. Toxicology 77:205–22.
  • Ma-Hock L, Burkhardt S, Strauss V, et al. (2009). Development of a short-term inhalation test in the rat using nano-titanium dioxide as a model substance. Inhal Toxicol 21:102–18.
  • Mantovani A, Sica A, Sozzani S, et al. (2004). The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25:677–86.
  • Martin TR, Chi EY, Covert DS, et al. (1983). Comparative effects of inhaled volcanic ash and quartz in rats. Am Rev Respir Dis 128:144–52.
  • Martinez FO, Gordon S. (2014). The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000Prime Rep 6:13.
  • Melgarejo E, Medina M, Sánchez-Jiménez F, et al. (2009). Monocyte chemoattractant protein-1: a key mediator in inflammatory processes. Int J Biochem Cell Biol 41:998–1001.
  • Miller K. (1979). Alterations in the surface-related phenomena of alveolar macrophages following inhalation of crocidolite asbestos and quartz dusts: an overview. Environ Res 20:162–82.
  • Mohr C, Gemsa D, Graebner C, et al. (1991). Systemic macrophage stimulation in rats with silicosis: enhanced release of tumor necrosis factor-α from alveolar and peritoneal macrophages. Am J Respir Cell Mol Biol 5:395–402.
  • Mornex JF, Leroux C, Greenland T, et al. (1994). From granuloma to fibrosis in interstitial lung diseases: molecular and cellular interactions. Eur Respir J 7:779–85.
  • Morrow PE. (1988). Possible mechanisms to explain dust overloading of the lungs. Fundam Appl Toxicol 10:369–84.
  • Morrow P. (1992). Dust overloading of the lungs: update and appraisal. Toxicol Appl Pharmacol 113:1–12.
  • Mosser DM, Edwards JP. (2008). Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8:958–69.
  • Muhle H, Bellmann B, Creutzenberg O, et al. (1991). Pulmonary response to toner upon chronic inhalation exposure in rats. Fundam Appl Toxicol 17:280–99.
  • Oberdörster G, Ferin J, Lehnert BE. (1994). Correlation between particle size, in vivo particle persistence, and lung injury. Environ Health Perspect 102 Suppl 5:173–9.
  • Pabst R, Gehrke I. (1990). Is the bronchus-associated lymphoid tissue (BALT) an integral structure of the lung in normal mammals, including humans? Am J Respir Cell Mol Biol 3:131–5.
  • Panaro MA, Mitolo V. (1999). Cellular responses to FMLP challenging: a mini-review. Immunopharmacol Immunotoxicol 21:397–419.
  • Panaro MA, Acquafredda A, Sisto M, et al. (2006). Biological role of the N-formyl peptide receptors. Immunopharmacol Immunotoxicol 28:103–27.
  • Porter DW, Ramsey D, Hubbs AF, et al. (2001). Time course of pulmonary response of rats to inhalation of crystalline silica: histological results and biochemical indices of damage, lipidosis, and fibrosis. J Environ Pathol Toxicol Oncol 20 Suppl 1:1-14.
  • Porter DW, Millecchia L, Robinson VA, et al. (2002). Enhanced nitric oxide and reactive oxygen species production and damage after inhalation of silica. Am J Physiol Lung Cell Mol Physiol 283:L485–93.
  • Porter DW, Hubbs AF, Mercer R, et al. (2004). Progression of lung inflammation and damage in rats after cessation of silica inhalation. Toxicol Sci 79:370–80.
  • Porter DW, Millecchia LL, Willard P, et al. (2006). Nitric oxide and reactive oxygen species production causes progressive damage in rats after cessation of silica inhalation. Toxicol Sci 90:188–97.
  • Privalova LI, Katsnelson BA, Yelnichnykh LN. (1987). Some peculiarities of the pulmonary phagocytotic response: dust retention kinetics and silicosis development during long term exposure of rats to high quartz dust levels. Br J Ind Med 44:228–35.
  • Rao KM, Porter DW, Meighan T, et al. (2004). The sources of inflammatory mediators in the lung after silica exposure. Environ Health Perspect 112:1679–86.
  • Rimal B, Greenberg AK, Rom WN. (2005). Basic pathogenetic mechanisms in silicosis: current understanding. Curr Opin Pulm Med 11:169–73.
  • Sellamuthu R, Umbright C, Roberts JR, et al. (2011). Blood gene expression profiling detects silica exposure and toxicity. Toxicol Sci 122:253–64.
  • Sellamuthu R, Umbright C, Roberts JR, et al. (2017). Molecular mechanisms of pulmonary response progression in crystalline silica exposed rats. Inhal Toxicol 29:53–64.
  • Sjöstrand M, Rylander R. (1984). Enzymes in lung lavage fluid after inhalation exposure to silica dust. Environ Res 33:307–11.
  • Vincent JH, Jones AD, Johnston AM, et al. (1987). Accumulation of inhaled mineral dust in the lung and associated lymph nodes: implications for exposure and dose in occupational lung disease. Ann Occup Hyg 31:375–93.
  • Warheit DB, Carakostas MC, Hartsky MA, et al. (1991). Development of a short-term inhalation bioassay to assess pulmonary toxicity of inhaled particles: comparisons of pulmonary responses to carbonyl iron and silica. Toxicol Appl Pharmacol 107:350–68.
  • Warheit D, Hansen J, Yuen I, et al. (1997). Inhalation of high concentrations of low toxicity dusts in rats results in impaired pulmonary clearance mechanisms and persistent inflammation. Toxicol Appl Pharmacol 145:10–22.
  • WHO. (2000). Concise International Chemical Assessment Document 24, Crystalline silica, quartz. Geneva: World Health Organization.
  • Williams GT, Williams WJ. (1983). Granulomatous inflammation-a review. J Clin Pathol 36:723–33.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.