Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 31, 2019 - Issue 7
314
Views
12
CrossRef citations to date
0
Altmetric
Research Articles

Prevention of crystalline silica-induced inflammation by the anti-malarial hydroxychloroquine

, & ORCID Icon
Pages 274-284 | Received 08 Jul 2019, Accepted 10 Sep 2019, Published online: 26 Sep 2019

References

  • Aits S, Jäättelä M, Nylandsted J. 2015. Methods for the quantification of lysosomal membrane permeabilization: a hallmark of lysosomal cell death. Methods Cell Biol. 126:261–285.
  • Beamer CA, Holian A. 2007. Antigen-presenting cell population dynamics during murine silicosis. Am J Respir Cell Mol Biol. 37(6):729–738.
  • Ben-Zvi I, Kivity S, Langevitz P, Shoenfeld Y. 2012. Hydroxychloroquine: from malaria to autoimmunity. Clin Rev Allerg Immunol. 42(2):145–153.
  • Biswas R, Hamilton RF, Holian A. 2014. Role of lysosomes in silica-induced inflammasome activation and inflammation in absence of MARCO. J Immunol Res. 2014:1.
  • Biswas R, Trout KL, Jessop F, Harkema JR, Holian A. 2017. Imipramine blocks acute silicosis in a mouse model. Part Fibre Toxicol. 14(1):36.
  • Boya P, Gonzalez-Polo R-A, Poncet D, Andreau K, Vieira HL, Roumier T, Perfettini J-L, Kroemer G. 2003. Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. Oncogene. 22(25):3927–3936.
  • Boya P, Kroemer G. 2008. Lysosomal membrane permeabilization in cell death. Oncogene. 27(50):6434–6451.
  • Bunderson-Schelvan M, Hamilton RF, Trout KL, Jessop F, Gulumian M, Holian A. 2016. Approaching a unified theory for particle-induced inflammation. In: Otsuki T, Yoshioka Y, Holian A, editors. Biological effects of fibrous and particulate substances. Tokyo, Japan: Springer Japan. p. 51–76.
  • Chen D, Xie J, Fiskesund R, Dong W, Liang X, Lv J, Jin X, Liu J, Mo S, Zhang T, et al. 2018. Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype. Nat Commun. 9(1):873.
  • Chen X, Wang N, Zhu Y, Lu Y, Liu X, Zheng J. 2017. The antimalarial chloroquine suppresses LPS-induced NLRP3 inflammasome activation and confers protection against murine endotoxic shock. Mediat Inflamm. 2017:1–11.
  • Gómez-Guzmán M, Jiménez R, Romero M, Sánchez M, Zarzuelo MJ, Gómez-Morales M, O’Valle F, López-Farré AJ, Algieri F, Gálvez J, et al. 2014. Chronic hydroxychloroquine improves endothelial dysfunction and protects kidney in a mouse model of systemic lupus erythematosus. Hypertension. 64(2):330–337.
  • Hamilton RF, Thakur SA, Mayfair JK, Holian A. 2006. MARCO mediates silica uptake and toxicity in alveolar macrophages from C57BL/6 mice. J Biol Chem. 281(45):34218–34226.
  • Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E. 2008. Silica crystals and aluminum salts mediate NALP-3 inflammasome activation via phagosomal destabilization. Nat Immunol. 9(8):847–856.
  • Jessop F, Hamilton RF, Rhoderick JF, Fletcher P, Holian A. 2017. Phagolysosome acidification is required for silica and engineered nanoparticle-induced lysosome membrane permeabilization and resultant NLRP3 inflammasome activity. Toxicol Appl Pharmacol. 318(Suppl C):58–68.
  • Jo E-K, Kim JK, Shin D-M, Sasakawa C. 2016. Molecular mechanisms regulating NLRP3 inflammasome activation. Cell Mol Immunol. 13(2):148–159.
  • Kawasaki H. 2015. A mechanistic review of silica-induced inhalation toxicity. Inhal Toxicol. 27(8):363–377.
  • Leung CC, Yu ITS, Chen W. 2012. Silicosis. Lancet. 379(9830):2008–2018.
  • Migliaccio CT, Buford MC, Jessop F, Holian A. 2008. The IL-4Rα pathway in macrophages and its potential role in silica-induced pulmonary fibrosis. J Leukocyte Biol. 83(3):630–639.
  • Olsen NJ, Schleich MA, Karp DR. 2013. Multifaceted effects of hydroxychloroquine in human disease. Semin Arthritis Rheum. 43(2):264–272.
  • Pfau JC, Schneider JC, Archer AJ, Sentissi J, Leyva FJ, Cramton J. 2004. Environmental oxygen tension affects phenotype in cultured bone marrow-derived macrophages. Am J Physiol Lung Cell Mol Physiol. 286(2):L354–L362.
  • Pollard KM. 2016. Silica, silicosis, and autoimmunity. Front Immunol. 7:97.
  • Rimal B, Greenberg A, Rom W. 2005. Basic pathogenetic mechanisms in silicosis: current understanding. Curr Opin Pulmon Med. 11(2):169–173.
  • Ruiz A, Rockfield S, Taran N, Haller E, Engelman RW, Flores I, Panina-Bordignon P, Nanjundan M. 2016. Effect of hydroxychloroquine and characterization of autophagy in a mouse model of endometriosis. Cell Death Dis. 7(1):e2059.
  • Sager TM, Wolfarth M, Leonard SS, Morris AM, Porter DW, Castranova V, Holian A. 2016. Role of engineered metal oxide nanoparticle agglomeration in reactive oxygen species generation and cathespin B release in NLRP3 inflammasome activation and pulmonary toxicity. Inhal Toxicol. 28(14):686–697.
  • Sayan M, Mossman BT. 2016. The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases. Part Fibre Toxicol. 13:51.
  • Serrano-Puebla A, Boya P. 2016. Lysosomal membrane permeabilization in cell death: new evidence and implications for health and disease: lysosomal membrane permeabilization and neurodegeneration. Ann NY Acad Sci. 1371(1):30–44.
  • Villamil Giraldo AM, Appelqvist H, Ederth T, Öllinger K. 2014. Lysosomotropic agents: impact on lysosomal membrane permeabilization and cell death. Biochm Soc Trans. 42(5):1460–1464.
  • Wang F, Yu L, Monopoli MP, Sandin P, Mahon E, Salvati A, Dawson KA. 2013. The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes. Nanomed Nanotechnol Biol Med. 9(8):1159–1168.
  • Yang J, Qu J, Summah H, Zhang J, Zhu Y, Jiang H. 2010. Protective effects of imipramine in murine endotoxin-induced acute lung injury. Eur J Pharmacol. 638(1–3):128–133.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.