TIME COURSE OF AIRWAY EPITHELIAL AND INFLAMMATORY CHANGES IN RATS EXPOSED TO MODERATE LEVELS OF OZONE

References

• Bassett, D. J. P., Bowen-Kelley, E., Elbon, C. L., and Reichenbaugh, S. S. 1988a. Rat lung recovery from 3 days of continuous exposure to 0.75 ppm ozone./ Toxicol. Environ. Health 25:329–347.
   Google Scholar
• Bassett, D. J. P., Bowen-Kelley, E., Brewester, E. L., Elbon, C. L., Reichenbaugh, S. S., Bunton, T., and Kerr, J. S. 1988b. A reversible model of acute lung injury based on ozone exposure. Lung 166:355–369.
   PubMed Web of Science ®Google Scholar
• Bhalla, D. K., and Crocker, T. T. 1987. Pulmonary epithelial permeability in rats exposed to 03. J. Toxicol. Environ. Health 21:73–87.
   PubMed Web of Science ®Google Scholar
• Bhalla, D. K., and Young, C. 1992. Effects of acute exposure to 03 on rats: sequence of epithe-lial and inflammatory changes in the distal airways. InhaL Toxicol. 4:17–31.
   Google Scholar
• Bhalla, D. K., Mannix, R. C., Kleinman, M. T., and Crocker, T. T. 1986. Relative permeability of nasal, tracheal, and bronchoalveolar mucosa to macromolecules in rats exposed to ozone./ Toxicol. Environ. Health 17:269–283.
   PubMed Web of Science ®Google Scholar
• Bhalla, D. K., Rasmussen, R. E., and Tjen, S. 1987. Interactive effects of 03, cytochalasin D, and vinblastine on transepithelial transport and cytoskeleton in rat airways. Am. J. Respir. MoL Biol. 3:119–129.
   Google Scholar
• Bhalla, D. K., Daniels, D. S., and Luu, N. T. 1992. Attenuation of 03 induced airway perme-ability in rats by pretreatment with cyclophosphamide, FPL55712 and indomethacin. Am.]. Respir. Cell MoL Biol. 7:73–80.
   PubMed Web of Science ®Google Scholar
• Devlin, R. B., McDonnell, W. F., Mann, R., Becker, S., House, D. E., Schreinemachers, D., and Koren, H. S. 1991. Exposure of humans to ambient levels of ozone for 6.6 hours causes cellular and biochemical changes in the lung. Am. J. Respir. Cell MoL Biol. 4:72–81.
   PubMed Web of Science ®Google Scholar
• Devlin, R. B., McDonnell, W. F., Becker, S., Madden, M., McGee, M. P., Perez, R., Hatch, G., House, D. E., and Koren, H. E. 1996. Time-dependent changes of inflammatory mediators in the lungs of humans exposed to 0.4 ppm ozone for 2 hr: A comparison of mediators found in bronchoalveolar lavage fluid 1 and 18 hr after exposure. Toxicol. AppL PharmacoL 138:176–185.
   PubMed Web of Science ®Google Scholar
• Driscoll, K. E., Volmuth, T. A., and Schlesinger, R. B. 1987. Acute and subchronic ozone inhala-tion in the rabbit: Response of alveolar macrophages./ Toxicol. Environ. Health 21:27–43.
   PubMed Web of Science ®Google Scholar
• Gordon, R. E., Case, B. W., and Kleinerman, J. 1983. Acute NO2 effects on penetration and transport of horseradish peroxidase in hamster respiratory epithelium. Am. Rev. Respir. Dis. 128:528–533.
   PubMed Web of Science ®Google Scholar
• Gunnison, A. F., Weidman, P. A., and Sobo, M. 1992. Enhanced inflammatory response to acute ozone exposure in rats during pregnancy and lactation. Fundam. AppL Toxicol. 19:607-612. Hatch, G. E., Slade, R., Stead, A. G., and Graham, J. A. 1986. Species comparison of acute inhalation toxicity of ozone and phosgene./ Toxicol. Environ. Health 19:43–53.
   Google Scholar
• Hatch, G. E., Slade, R., Stead, A. G., Harris, L. P., McDonnell, W. F., Devlin, R. B., Koren, H. S., Costa, D. L., and McNee, J. 1994. Ozone dose and effects in humans and rats. A comparison using oxygen-18 labeling and bronchoalveolar lavage. Am. J. Respir. Crit. Care Med. 150:676–683.
   Web of Science ®Google Scholar
• Hotchkiss, J. A., Harkema, J. R., Sun, J. D., and Henderson, R. F. 1989. Comparison of acute ozone-induced nasal and pulmonary inflammatory responses in rats. Toxicol. AppL PharmacoL 98:289–302.
   PubMed Web of Science ®Google Scholar
• Hulbert, W. C., Walker, D. C., Jackson, A., and Hogg, J. C. 1981. Airway permeability to horseradish peroxidase in guinea pigs: The repair phase after injury by cigarette smoke. Am. Rev. Respir. Dis. 123:320–326.
   PubMed Web of Science ®Google Scholar
• Kleeberger, S. R., Kolbe, J., Turner, C., and Spannhake, E. W. 1989. Exposure to 1 ppm ozone attenuates the immediate antigenic response of canine peripheral airways./ Toxicol. Environ. Health 28:349–362.
   PubMed Web of Science ®Google Scholar
• Koren, H. S., Devlin, R. B., Graham, D. E., Mann, R., McGee, M. P., Horstman, D. H., Kozumbo, W. J., Becker, S., House, D. E., McDonnell, W. F., and Bromberg, P. A. 1989.
   Google Scholar
• Ozone-induced inflammation in the lower airways of human subjects. Am. Rev. Respir. Dis. 139:407–415.
   Google Scholar
• Macy, E., Kemeny, M., and Saxon, A. 1988. Enhanced ELISA: How to measure less than 10 picograms of a specific protein (immunoglobulin) in less than 8 hours. EASES J. 2:3003–3009.
   Google Scholar
• Mautz, W. J., McClure, T. R., Reischl, P., Phalen, R. F., and Crocker, T. T. 1985. Enhancement of ozone-induced lung injury by exercise.]. Toxicol. Environ. Health 16:841–854.
   PubMed Web of Science ®Google Scholar
• Miller, P. D., Gordon, T., Warnick, M., and Amdur, M. 0. 1986. Effect of ozone and histamine on airway permeability to horseradish peroxidase in guinea pigs. J. Toxicol. Environ. Health 18:121–132.
   PubMed Web of Science ®Google Scholar
• Schwerer, B., Bach, M., and Bernheimer, H. 1987. ELISA for determination of albumin in the nanogram range: Assay in cerebrospinal fluid and comparison with radical immunodiffusion. Clin. Chim. Acta 163:237–244.
   PubMed Web of Science ®Google Scholar
• Seltzer, J., Bigby, B. G., Stulbarg, M., Holtzman, M. J., Nadel, J. A., Ueki, I. F., Leikauf, G. D., Goetzl, E. J., and Boushey, H. A. 1986. 03-induced change in bronchial reactivity to methacholine and airway inflammation in humans.]. AppL PhysioL 60:1321–1326.
   Google Scholar
• Van Bree, L., Marra, M., and Rombout, P. J. A. 1992. Differences in pulmonary biochemical and inflammatory responses of rats and guinea pigs resulting from daytime or nighttime, sin-gle and repeated exposure to ozone. Toxicol. AppL PharmacoL 116:209–216.
   PubMed Web of Science ®Google Scholar
• Young, C., and Bhalla, D. K. 1992. Time course of permeability changes and PMN flux in rat trachea following 03 exposure. Fundam. AppL Toxicol. 18:175–180.
   PubMedGoogle Scholar