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Inhalation Toxicology
International Forum for Respiratory Research
Volume 11, 1999 - Issue 9
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Research Article

TIME-COURSE ANALYSIS OF TYPE II CELL HYPERPLASIA AND ALVEOLAR BRONCHIOLIZATION IN RATS TREATED WITH DIFFERENT PARTICULATES

Pages 837-854 | Published online: 01 Oct 2008

REFERENCES

  • Ames, B. N., and Gold, L. S. 1990. Too many rodent carcinogens: Mitogenesis increasis mutagenesis. Science249:970–971.
  • Auer, G., Askensten, U., and Ahrens, 0.1989. Cytophotometry. Hum. PathoL 20:518–527.
  • Barth, P. J., Muller, B., Wagner, U., and Bittinger, A. 1994. Assessment of proliferative activity in type II pneumocytes after inhalation of NO2 by AgNOR-analysis. Exp. Toxicol. PathoL 46:335–342.
  • Bocking, A., Adler, C.-P., Common, H. H., Hilgarth, M., Granzen, B., and Auffermann, W. 1984. Algorithm for a DNA-cytophotometric diagnosis and grading of malignancy. Ana/. Quant. CytoL 6:1–8.
  • Bocking, A., Giroud, F., and Reith, A. 1995. Consensus report of the ESACP task force on standard-ization of diagnostic DNA image cytometry. Anal. Cell. Pathol. 8:67–74.
  • Boorman, G. A. 1985. Bronchiolar/alveolar adenoma, lung, rat. In Respiratory system, eds. T. C. Jones, U. Mohr, and R. E. Hunt, pp. 99–101. Berlin: Springer Verlag.
  • Cohen, S. M., and Ellwein, L. B. 1990. Cell proliferation in carcinogenesis. Science249:1007-1011. Dormans, J., and van Bree, L. 1995. Function and response type II cells to inhaled toxicants. lnhal. Toxicol. 7:319–342.
  • Dreher, D., and Junod, A. F. 1996. Role of oxygen free radicals in cancer development. Eur. J. Cancer32:30–38.
  • Driscoll, K. E. 1994. Macrophage inflammatory proteins: Biology and role in pulmonary inflamma-tion. Exp. Lung Res. 20(6):473–490.
  • Driscoll, K. E., Carter, J. M., Howard, B. W., Hassenbein, D. G., Pepelko, W., Baggs, R. B., and Oberdörster, G. 1996. Pulmonary inflammatory, chemokine, and mutagenic responses in rats after subchronic inhalation of carbon black. Toxicol. Appl. Pharmacol. 136: 372–380.
  • Driscoll, K. E., Deyo, L. C., Carter, J. M., Howard, B. W., Hassenbein, D. G., and Bertram, T. A. 1997. Effects of particle exposure and particle-elicited inflammatory cells on mutation in rat alveolar epithelial cells. Carcinogenesis 18(2):423–430.
  • Friemann, J., Friedrichs, K. H., Salopek, S., Grover, R., Dykgers, A., Rosenbruch, M., and Schlipköter, H.-W. 1992. Fibrogenität pulmonal retinierter Talkumstäube in Abhängigkeit von ihrer geometrischen und mineralogischen Beschaffenheit. Tierexperimentelle und humanpathologis-che Untersuchungsbefunde. Verb. Dtsch. Ges. Path. 76: 266.
  • Friemann, J., Pott, F., Wilk, K. B., Ahrens, 0., Rosenbruch, M., Hilscher, W., and Schlipköter, H.-W. 1994. Pulmonary alveolar proteinosis in rats after administration of quartz: Its possible role in morphogenesis of lung cancer.]. Cancer Res. Clin. Oncol. 120: 348–353.
  • Goddard, M. J., Wilson, B., and Grant, J. W. 1991. Comparison of comercially available cytokeratin antibodies in normal and neoplastic adult epithelial and non-epithelial tissues.]. Clin. PathoL 44:660–663.
  • Hedley, D. W., Friedlaender, M. L., Taylor, I. W., Rugg, C. A., and Musgrove, E. A. 1983. Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytome-try. J. Histochem. Cytochem. 31:1333–1335.
  • Heinrich, U. 1994. Carcinogenic effects of solid particles. In Toxic and carcinogenic effects of solid particles in the respiratory tract, eds., D. Dungworth, U. Mohr, J. Mauderly, and G. Oberdörster, pp. 57–73. Washington, DC: ILSI Press.
  • Heinrich, U., Fuhst, R., Rittinghausen, S., Creutzenberg, 0., Bellman, B., Koch, W., and Levsen, K. 1995. Chronic inhalation exposure of Wistar rats and two different strains of mice to diesel engine exhaust, carbon black, and titanium dioxide. InhaL ToxicoL 7:533–556.
  • Hext, P. M. 1994. Current perspectives on particulate induced pulmonary tumours. Hum. Exp. Toxicol. 13:700–715.
  • Hilscher, W., Rosmanith, J., Thome, E., and Koep, D. 1991. Morphometrische Untersuchungen an den Lungen und Lymphknoten von Ratten nach intratrachealer Instillation quarzhaltiger Stäube zur Erfassung der minimalen fibrogenen Dosis. Silikosebericht Nordrhein-Westfalen 18:223–238.
  • Holland, L. M., Gonzales, M., Wilson, J. S., and Tillery, M. I. 1983. Pulmonary effects of shale dusts in experimental animals. In Health issues released to metal and nonmetallic mining, eds. W. L. Wagner, W. N. Rom, and J. A. Merchant, pp. 485–496. Boston: Butterworth.
  • ILSI. 1998. Workshop: Relevance of the rat as a model for hazard and risk characterization of inhaled poorly soluble, nonfibrous, nongenotoxic particles, Washington, DC: March 23–24.
  • Johnson, N. F., Smith, D. M., Sebring, R., and Holland, L. M. 1987. Silica-induced alveolar cell tumors in rats. Am.]. Med. 11:93–107.
  • Kawada, H., Horiuchi, T., Shannon, J., Kuroki, Y., Voelker, D., and Mason, R. 1989. Alveolar type-II cells, surfactant protein A, and the phospholipid components of surfactant in acute silicosis in the rat. Am. Rev. Respir. Dis. 140:460.
  • Liu, J.-Y., Morris, G. F., Lei, W.-H., Corti, M., Brody, and A. R. 1996. Up-regulated expression of transforming growth factor-a in the bronchiolar-alveolar duct regions of asbestos-exposed rats. Am.]. Pathol. 49: 205–217.
  • McDivitt, R. W., Stone, K. R., Craig, R. B., and Meyer, J. S. 1985. A comparison of human cell kinet-ics measured by flow cytometry and thymidine labeling. Lab. Invest. 52:287–291.
  • Mellin, W. 1990. Cytophotometry in tumor pathology. A critical review of methods and applications, and some results of DNA analysis. Pathol. Res. Pract. 186:37–62.
  • Meyer, J. S., and Coplin, M. D. 1989. Thymidine labeling index, flow cytometric S-phase measure-ment, and DNA-index in human tumors. Comparisons and correlations. Am. J. Clin. Pathol. 89:586–595.
  • Mohr, U. 1992. International classification of rodent tumors. Part. The rat, 1. Respiratory system, pp. 31–49. Lyon: International Agency for Research in Cancer.
  • Moll, R., Franke, W. W., Schiller, D. L., Geiger, B., and Krepler, R. 1982. The catalog of cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Ce//31:11–24.
  • Muhle, H., Takenaka, S., Mohr, U., Dasenbrock, C., and Mermel-Stein, R. 1989. Lung tumor induc-tion upon long-term low-level inhalation of crystalline silica. Am.]. Ind. Med. 15:343–356.
  • Muhle, H., Kittel, B., Ernst, H., Mohr, U., and Mermelstein, R. 1995. Neoplastic lung lesions in rat after chronic exposure to crystalline silica. Scand. J. Work. Environ. Health 21\(suppl. 2):27–29.
  • Nasreen, N., Hartman, D. L., Mohammed, K. A., and Antony, V. B. 1998. Talc-induced expression of C-C and C-X-C chemokines and intercellular adhesion molekule-1 in mesothelial cells. Am. J. Respir. Crit. Care Med. 158:971–978.
  • Nehls, P., Seiler, F., Rehn, B., Greferath, R., and Bruch, J. 1997. Formation and persistence of 8-oxoguanine in rat lung cells as an important determinant for tumor formation following particle exposition. Environ. Health Perspect. 105\(suppl. 5):1291–1296.
  • Nolte, T., Thiedemann, K. U., Dungworth D. L., Ernst, H., Paulini, I., Heinrich, U., Dasenbrock, C., Peters, Ueberschar, S., and Mohr, U. 1993. Morphology and histogenesis of squamous cell metaplasia of the rat lung after chronic exposure to a pyrolized pitch condensate and/or carbon black, or to combinations of pyrolized pitch condensate, carbon black and irritant gases. Exp. Toxicol. Pathol. 45: 135–144.
  • Oberdörster, G. 1997. Pulmonary carcinogenicity of inhaled particles and the maximum tolerated dose. Environ. Health Perspect. 105(supp I. 5):1347–1356.
  • Oberdörster, G., Ferin, J., and Lehnert, B. E. 1994. Correlation between particle size, in vivo particle persistence, and lung injury. Environ. Health Perspect. 102:173–179.
  • Parrado, C., Falkmer, U. G., Haag, A., Falkmer, S., Ahrens, 0., Rius, F., and Grimelius, L. 1995. A technique for automaticAnteractive assessment of the proliferating fraction of neoplastic cells in solid tumors. A methodological study on Ki-67 immunoreactive cells in human mammary carci-nomas, including a comparison with the results of conventional S-phase fraction assessment by means of DNA cytometry. Gen. Diagn. Pathol. 141: 215–227.
  • Pinkerton, K. E., Dodge, D. E., Cederdahl-Demmler, J., Wong, V. J., Peake, J., Haselton, C. J., Mellick, P. W., Singh, G., and Plopper, C. G. 1993. Differentiated bronchiolar epithelium in alveolar ducts of rats exposed to ozone for 20 months. Am.]. Pathol. 142: 947–956.
  • Pott, F., Dungworth, D. L., Heinrich, U., Muhle, H., Kamino, K., Germann, P.-G., Roller, M., Rippe, R.-M., and Mohr, U. 1994. Lung tumors in rats after intratracheal instillation of dusts. Ann. Occup. Hyg. suppL 38:357–363.
  • Rehm, S., Lijinsky, W., Thomas, B. J., and Kaprzak, B. H. 1993. Clara cell antigen in normal and migratory dysplastic Clara cells, and bronchioloalveolar carcinoma of Syrian hamsters induced by N-nitrosomethyl-n-heptylamine. Virchows Archly 8 Cell Pathol. 64: 181–190.
  • Reznik-Schuller, H. M., and Reznik, G. 1982. Morphology of spontaneous and induced tumours in the bronchio-alveolar region of F344 rats. Anticancer Res. 2: 53–58.
  • Ryan, R. M., Mineo-Kuhn, M. M., Kramer, C. M., and Finkelstein, J. N. 1994. Growth factor alters neonatal type II alveolar epithelial cell proliferation. Am. J. Physiol. 266(Lung Cell Mol. PhysioL 10):L17—L22. Schultz, M. 1996. Comparative pathology of dust-induced pulmonary lesions: Significance of animal studies to humans. Inhal. Toxicol. 8:433-456. van den Heuvel, M. M., Smit, H. J. M., Barbierato, S. B., Havenith, C. E. G., Beelen, R. H. J., and Postmus, P. E. 1998. Talc-induced inflammation in the pleural cavity. Eur. Respir. J. 12: 1419–1423.
  • Williams, A. 0., Flanders, K. C., and Saffiotti, U. 1993. Immunohistochemical localization of trans-forming growth factor-81 in rats with experimental silicosis, alveolar type II hyperplasia, and lung cancer. Am.]. Pathol. 142: 1831–1840.
  • Williams, A. 0., Knapton, A. D., Ifon, E. T., and Saffiotti, U. 1996. Transforming growth factor beta expression and transformation of rat lung epithelial cells by crystalline silica (quartz). Int. J. Cancer 65:639–649.
  • Yi, E. S., Lee, H., Yin, S., Piguet, P., Sarosi, I., Kaufmann, S., Tarpley, J., Wang, V. S. L., and Ulrich, T. S. 1996. Platelet-derived growth factor causes pulmonary cell proliferation and collagen deposition in vivo. Am.]. Pathol. 149:539–548.

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