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Inhalation Toxicology
International Forum for Respiratory Research
Volume 11, 1999 - Issue 1
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Research Article

PATHOLOGICAL AND IMMUNOLOGICAL EFFECTS OF RESPIRABLE COAL FLY ASH IN MALE WISTAR RATS

Pages 51-69 | Published online: 01 Oct 2008

References

  • Arts, J. H. E., Penninks, A. H., and Hoeksema, H. W. 1994. Toxicity of coal fly ash and lytag dust upon intratracheal instillation. In Toxic and carcinogenic effects of solid particles in the respira-tory tract, ed. U. Mohr, pp. 443–446. Washington, DC: ILSI Press.
  • Bajpai, R., Waseem, M., and Kaw, J. L. 1994. Pulmonary response to cadmium and nickel coated fly ash.]. Environ. Pathol. Toxicol. Oncol. 13(4):251–257.
  • Bajpai, R., Waseem, M., Dogra, S., and Kaw, J. L. 1996. Pulmonary clearance of Candida albicans: Effect of exposure to native and metal-coated fly ash. Mycopathologia 135:103–108.
  • Becker, S., Soukup, J. M., Gilmour, M. I., and Devlin, R. B. 1996. Stimulation of human and rat alve-olar macrophages by urban air particulates: Effects on oxidant radical generation and cytokine production. Toxicol. Appl. Pharmacol. 141:637–648.
  • Bice, D. E., Hahn, F. F., Benson, J., Carpenter, R. L., and Hobbs, C. 1987. Comparative lung immunotoxicity of inhaled quartz and coal combustion fly ash. Environ. Res. 43:374–389.
  • Borm, P. J. A., 1997. Toxicity and occupational health hazards of coal fly ash. A review of data and comparison to coal mine dust. Ann. Occup. Hyg. 41(6):659–676.
  • Broeckaert, L., Buchet, J. P., Huaux, F., Lardot, C., Lison, D., and Yager, J. W. 1997. Reduction of the ex vivo production of tumor necrosis factor alpha by phagocytes after administration of coal fly ash and copper smelter dust.]. Toxicol. Environ. Health 15:189–202.
  • Burns, C. A., and Zarkower, A. 1982. The effects of silica and fly ash dust inhalation on alveolar macrophages effector cell function.]. Reticuloendothel. Soc. 32:449–459.
  • Chauhan, S. S., Chaudhary, V., Narayan, S., and Misra, U. K. 1987. Cytotoxicity of inhaled coal fly ash in rats. Environ. Res. 43:1–12.
  • Davison, R. L., Natusch, D. F. S., and Wallace, J. R. 1974. Trace elements in fly ash. Environ. Sci. Technol. 8:1107–1113.
  • de Jong, W. H., Steerenberg, P. A., Ursem, P. S., Osterhaus, A. D. M. E., Vos, J. G., and Ruitenberg, E. J. 1980. The athymic nude rat. III Natural cell-mediated cytotoxicity. Clin. Immunol. Immuno-pathol. 17: 163–172.
  • Dixit, R., Khanna, A. K., Waseem, M., Dogra, S., and Kaw, J. L. 1990. Alterations in in vitro func-tional activities of alveolar macrophages exposed in vivo to mineral dusts. Vet. Hum. Toxicol. 32:517.
  • Dockery, D. W., and Pope C. A. 1994. III. Acute respiratory effects of particulate air pollution. Ann. Rev. Public Health 15:107–132.
  • Dogra, S., and Kaw, J. L. 1993. Pulmonary immunotoxic potential of coal fly ash. Int. J. Toxicol. Occup. Environ. Health 2:63–67.
  • Dogra, S., Khanna, A. K., and Kaw, J. L. 1995. Alterations in the pulmonary and systemic immune response in rats exposed to coal fly ash. Immunopharmacology29(2):1 03-109.
  • Gulyas, H., and Gercken, G. 1988. Cytotoxicity to alveolar macrophages of airborne particles and waste incinerator fly-ash fractions. Environ. Pollut. 51:1–18.
  • Gulyas, H., Labedzka, M., and Gercken, G. 1990. Depression of alveolar macrophage hydrogen per-oxide and superoxide anion release by mineral dusts: correlation with antimony, lead and arsenic contents. Environ. Res. 51(2):218–229.
  • Hackett, N. A. 1983. Cell proliferation in lung following acute fly ash exposure. Toxicology 27: 273–286.
  • Hill, J. 0., Gray, R. H., DeNee, P. B., and Newton, G. J. 1982. Comparative damage to alveolar macrophages after phagocytosis of respirable particles. Environ. Research 27:95–109.
  • Killingsworth, C. R., Alessandrini, F., Krishna Murthy, G. G., Catalano, P. J., Paulauskis, J. D., and Godleski, J. J. 1997. Inflammation, chemokine expression and death in monocrotaline-treated rats following fuel oil ash inhalation. Inhal. Toxicol. 9:541–565.
  • Kodavanti, U. P., Jaskot, R. H., Bonner, J., Badgett, A., and Dreher, K. L. 1996. Eosinophilic lung inflammation in particulate-induced lung injury: Technical consideration in isolating RNA for gene expression studies. Exp. Lung Res. 22:541–554.
  • Kodavanti, U. P., Jaskot, R. H., Costa, D. L., and Dreher, K. L. 1997. Pulmonary proinflammatcry gene induction following acute exposure to residual oil fly ash: Roles of particle-associated metals. InhaL ToxicoL 9:679–701.
  • Kondo, T., Takahashi, S., Sato, H., Yamada, M., Kikuchi, T., and Furuya, K. 1993. Cytotoxicity of size-density fractionated coal fly ash in rat alveolar macrophages cultured in vitro. ToxicoL In Vitro 7:61–67.
  • Labedzka, M., Gulyas, H., and Gercken, G. 1991. Zymosan-induced chemiluminescence of alveolar macrophages: depression by inorganic dust constituents. Arch. Environ. Contam. Toxicol. 21: 51–57.
  • Lantz, R. C., and Hinton, D. E. 1986. Development of alterations in hamster distal lung following exposure to fly ash from fluidized bed coal combustion: A morphometric study. ToxicoL Appl. PharmacoL 82:132–139.
  • Liu, W. K., Wong, M. H., and Tam, N. F. Y. 1987. Cytotoxicity of incinerator fly ash on alveolar macrophages./ Test. Eval. 153:3–8.
  • Mazanec, M. B., Nedrud, J. G., Kaetzel, C. S., and Lamm, M. L. 1993. A three-tiered view of the role of IgA in mucosal defense. Immunol. Today 14:430–435.
  • Negishi, T. 1994. Accumulation of alveolar macrophages induced by inhalation exposure of coal fly ash in golden hamsters lungs. Exp. Anim. 43:61–78.
  • Negishi, T. 1995. Lung clearance of particles following excessive deposition of fly ash in golden hamsters. Exp. Anim. 44:131–138.
  • Raabe, 0. G. 1982. Deposition and clearance of inhaled aerosols. In Mechanism in respiratory toxi-cology, eds. H. Witschi and P. Nettesheim, vol. 1, pp. 27–46. Boca Raton, FL: CRC Press.
  • Ruitenberg, E. J., and Van Noorle Jansen, L. M. 1975. Effect of Corynebacterium parvum on the course of a Listeria monocytogenes infection in normal and congenitally athymic (nude) mice. Zbl. Bakt. Hyg. I. Abt. Orig. A 231:197–205.
  • Ruitenberg, E. J., Van Noorle Jansen, L. M., Kruizinga, W., and Steerenberg, P. A. 1976. Effect of pre-treatment with Bacillus Calmette Guerin on the course of a Listeria monocytogenes infection in normal and congenitally athymic (nude) mice. Br.]. Exp. PathoL 57:310–315.
  • Shami, S. G., Silbaugh, S. A., Hahn, F. F., Griffith, W. C., and Hobbs, C. H. 1984. Cytokinetic and morphological changes in the lungs and lung-associated lymph nodes of rats after inhalation of fly ash. Environ. Res. 35:373–393.
  • Srivastava, P. K., and Misra, U. K. 1985. Cytotoxicity of intratracheally administered coal fly ash: Studies on lipids in the lungs of rats. Arch. Environ. Contam. 14:95–103.
  • Srivastava, P. K., Chaudhary, V. K., Chauhan, S. S., Srivastava, V. K., and Misra, U. K. 1984. Bio-chemical and pathological effects of fly ash on lung, liver and blood of rats. Arch. Environ. Contam. ToxicoL 13:441–452.
  • Srivastava, V. K., Srivastava, P. K., and Misra, U. K. 1985. Polycyclic aromatic hydrocarbons of coal fly ash: Analysis by gas liquid chromatography using nematic liquid crystals.]. ToxicoL Environ. Health 15:333–337.
  • Staszyc, J., Krolokowska-Prasal, I., Matysiak, W., Korobowicz, E., Chrost, L., and Kusmierczyk, S. 1987. Experimentell vergleichende Untersuchungen Ober die Reaktionsfähigkeit des Lung-engewebes auf intratracheal eingeführte Kraftwerksasche. Gegenbaurs. MorphoL Jahrbuch 133: 747–759.
  • Stein-Streilein, J., Bennett, M., Mann, D., and Kumar, V. 1983. Natural killer cells in mouse lung: Surface phenotype, target preference, and response to local influenza virus infection./ ImmunoL 131:2699–2704.
  • Tilney, N. L. 1971. Patterns of lymphatic drainage in the adult laboratory rat.]. Anat. 109:369-383. Van Bree, L., Reuzel, P. G. J., Verhoef, M. A., Bos, J., and Rombout, P. J. A. 1990. Effects of acute inhalation of respirable coal fly ash on metabolic defense capability of the rat lung. lnhaL ToxicoL 2:361–373.
  • Van Loveren, H., Rombout, P. J. A., Wagenaar, S. S., Walvoort, H. C., and Vos, J. G. 1988. Effects of ozone on the defense to a respiratory Listeria monocytogenes infection in the rat. Suppression of macrophage function and cellular immunity and aggravation of histopathology in lung and liver during infection. Toxicol. Appl. Pharmacol. 94: 374–393.
  • Van Soolingen, D., Moolenbeek, C., and Van Loveren, H. 1990. An improved method of bron-choalveolar lavage of lungs of small laboratory animals. Short report. Lab. Anim. 24:197–199.
  • Vos, J. G., Krajnc, I. E., and Beekhof, P. 1982. Use of the enzyme-linked immunosorbent assay(E LISA) in immunotoxicity testing. Environ Health Perspect. 43:115–121.

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