Cardiac autonomic denervation and expression of neurotrophins (NGF and BDNF) and their receptors during experimental Chagas disease

References

• Aloe L, Alleva E, Bohm A, Levi-Montalcini R. 1986. Aggressive behavior induces release of nerve growth factor from mouse salivary gland into the bloodstream. Neurobiol 83:6184–6187.
   Google Scholar
• Arias ER, Valle-Leija P, Morales MA, Cifuentes F. 2014. Differential contribution of BDNF and NGF to long-term potentiation in the superior cervical ganglion of the rat. Neuropharmacol 81:206–214.
   PubMed Web of Science ®Google Scholar
• Bennett AD, Taglialatela G, Perez-Polo R, Hulsebosch CE. 1999. NGF levels decrease in the spinal cord and dorsal root ganglion after spinal hemisection. Neuroreport 10:889–893.
   PubMed Web of Science ®Google Scholar
• Benziger CP, do Carmo GAL, Ribeiro ALP. 2017. Chagas cardiomyopathy: Clinical Presentation and management in the Americas. Cardiol Clin 35:31–47.
   PubMed Web of Science ®Google Scholar
• Bothwell M. 2016. Recent advances in understanding neurotrophin signaling. F1000Res [Online] Available from: https://f1000research.com/articles/5-1885/v1 [Accessed 28 Jul 2016]
   Google Scholar
• Bradford M. 1976. A rapid and sensitive method for the quantification of micrograms quantities of protein utilizing the principle of protein dye binding. Anal Biochem 72:248–254.
   PubMed Web of Science ®Google Scholar
• Caporali A, Pani E, Horrevoets AJG, Kraenkel N, Oikawa A, Sala-Newby GB, Meloni M, et al. 2008. The neurotrophin receptor p75NTR triggers endothelial cell apoptosis and inhibits angiogenesis: Implications for diabetes induced impairment of reparative neovascularization. Circ Res 103:e15–e26.
   PubMed Web of Science ®Google Scholar
• Costa HS, Lima MMO, Silva MG, Alencar MCN, Nunes MCP, Camargos ERS, Martinelli PM, et al. 2014. Effect of acute aerobic exercise on serum BDNF levels in patients with Chagas heart disease. Int J Cardiol 174:828–830.
   PubMed Web of Science ®Google Scholar
• Donovan MJ, Lin MI, Wiegn P, Ringstedt T, Kraemer R, Hahn R, Wang S, et al. 2000. Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization. Development 127:4531–4540.
   PubMed Web of Science ®Google Scholar
• Emanueli C, Meloni M, Hasan W, Fulgenzi BAH. 2014. The biology of neurotrophins: Cardiovascular function. In: Lewin GR, Carter BD, Editors. Neurotrophic factors, handbook of experimental pharmacology. Berlin: Springer. p 309–328.
   Google Scholar
• Feng N, Huke S, Zhu G, Tocchetti CG, Shi S, Aiba T, Kaludercic N, et al. 2015. Constitutive BDNF/TrkB signaling is required for normal cardiac contraction and relaxation. Proc Natl Acad Sci USA 112:61880–61885.
   Web of Science ®Google Scholar
• Govoni S, Pascale A, Amadio M, Calvillo L, D’Elia E, Cereda C, Fantucci P, et al. 2011. NGF and heart: Is there a role in heart disease? Pharmacol Res 63:266–277.
   PubMed Web of Science ®Google Scholar
• Habecker BA, Bilimoria P, Linick C, Gritman K, Lorentz CU, Woodward W, Birren SJ, et al. 2008. Regulation of cardiac innervation and function via the p75 neurotrophin receptor. Auton Neurosci 140:40–48.
   PubMed Web of Science ®Google Scholar
• Hasan W, Jama A, Donohue T, Wernli G, Onyszchuk G, Al-Hafez B, Bilgen M, et al. 2006. Sympathetic hyperinnervation and inflammatory cell NGF synthesis following myocardial infarction in rats. Brain Res 1124:142–154.
   PubMed Web of Science ®Google Scholar
• Hiltunen JO, Laurikainen A, Vakeva A, Meri S, Saarma M. 2001. Nerve growth factor and brain-derived neurotrophic factor mRNAs are regulated in distinctcellpopulations of ratheart after ischaemia and reperfusion. J Pathol 194:247–253.
   PubMed Web of Science ®Google Scholar
• Junqueira Junior LF. 2012. Insights into the clinical and functional significance of cardiac autonomic dysfunction in Chagas disease. Rev Soc Bras Med Trop 45:243–252.
   PubMed Web of Science ®Google Scholar
• Karnovsky MJ. 1965. A formaldehyde-glutaraldehyde fixative of high osmolality for use in electron microscopy. J Cell Biol 27:137–138.
   Web of Science ®Google Scholar
• Lanni C, Stanga S, Racchi M, Govoni S. 2010. The expanding universe of neurotrophic factors: Therapeutic potential in aging and age-associated disorders. Curr Pharm Des 16:698–717.
   PubMed Web of Science ®Google Scholar
• Lee R, Kermani P, Teng KK, Hempstead BL. 2001. Regulation of cell survival by secreted proneurotrophins. Science 294:1945–1948.
   PubMed Web of Science ®Google Scholar
• Lima MMO, Nunes MCP, Nascimento B, Costa HS, Sousa LAP, Teixeira AL, Rocha MOC, Ribeiro ALP. 2013. Improvement of the functional capacity is associated with BDNF and autonomic modulation in Chagas disease. Int J Cardiol 167:2363–2366.
   PubMed Web of Science ®Google Scholar
• Lorentz CU, Parrish DC, Alston EN, Pellegrino MJ, Woodward WR, Hempstead BL, Habecker BA. 2013. Sympathetic denervation of peri-infarct myocardium requires the p75 neurotrophin receptor. Exp Neurol 249:111–119.
   PubMed Web of Science ®Google Scholar
• Machado ABM, Machado CRS, Gomes CB. 1975. Depletion of heart norepinephrine in experimental acute myocarditis caused by Trypanosoma cruzi. Experientia 31:1202–1203.
   PubMedGoogle Scholar
• Machado ABM, Machado CRS, Gomez MV. 1979. Trypanosoma cruzi: Acetylcholine content and cholinergic innervation of the heart in rats. Exp Parasitol 47:107–115.
   PubMed Web of Science ®Google Scholar
• Machado CR, Machado AB, Chiari CA. 1978. Recovery from heart norepinephrine depletion in experimental Chagas’ disease. Am J Trop Med Hyg 27:20–24.
   PubMed Web of Science ®Google Scholar
• Machado CRS, Gomez MV, Machado AB. 1987. Changes in choline acetyltransferase activity of rat tissues during Chagas’ disease. Braz J Med Biol Res 20:697–702.
   PubMed Web of Science ®Google Scholar
• Machado CRS, Ribeiro ALP. 1989. Experimental American trypanosomiasis in rats: Sympathetic denervation, parasitism and inflammatory process. Mem Inst Oswaldo Cruz 84:549–556.
   PubMed Web of Science ®Google Scholar
• Markus A, Patel TD, Snider WD. 2002. Neurotrophic factors and axonal growth. Curr Opin Neurobiol 12:523–531.
   PubMed Web of Science ®Google Scholar
• Martinelli PM, Camargos ERDS, Azevedo AA, Chiari E, Morel G, Machado CRDS. 2006. Cardiac NGF and GDNF expression during Trypanosoma cruzi infection in rats. Auton Neurosci 130:32–40.
   PubMed Web of Science ®Google Scholar
• Martinelli PM, Rocha MO, Teixeira AL, Nunes MCP, Camargos ERS. 2011. Brain-derived neurotrophic factor is up regulated in chronic Chagas disease. Int J Cardiol 149:277–278.
   PubMed Web of Science ®Google Scholar
• Meloni M, Caporali A, Graiani G, Lagrasta C, Katare R, Linthout SV, Spillmann F, et al. 2010. Nerve growth factor promotes cardiac repair following myocardial infarction. Circ Res 106:1275–1284.
   PubMed Web of Science ®Google Scholar
• Molina RBG, Matsubara BB, Hueb JC, Zanati SG, Meira DA, Cassolato JL, Paiva SAR, Zornoff LAM. 2006. Dysautonomia and ventricular dysfunction in the indeterminate form of Chagas disease. Int J Cardiol 113:188–193.
   PubMed Web of Science ®Google Scholar
• Prata A. 2001. Clinical and epidemiological aspects of Chagas disease. Lancet. Infect Dis 1:92–100.
   PubMedGoogle Scholar
• Rassi A, Rassi A, Marin-Neto JA. 2010. Chagas disease. Lancet 375:1388–1402.
   PubMed Web of Science ®Google Scholar
• Rocha MOC, Ribeiro ALP, Teixeira MM. 2003. Clinical management of chronic chagas cardiomyopathy. Front Biosci 8:44–54.
   PubMed Web of Science ®Google Scholar
• Serra-Millàs M. 2016. Are the changes in the peripheral brain-derived neurotrophic factor levels due to platelet activation? World J Psychiatr 6:84–101.
   PubMed Web of Science ®Google Scholar
• Siao CJ, Lorentz CU, Kermani P, Marinic T. 2012. ProNGF, a cytokine induced after myocardial infarction in humans, targets pericytes to promote microvascular damage and activation. J Exp Med 209:2291–2305.
   PubMed Web of Science ®Google Scholar
• Silva LHP, Nussensweig V. 1953. Sobre uma cepa de Trypanosoma cruzi altamente virulenta para o camundongo branco. Folia Clinica Et Biologica 20:191–208.
   Google Scholar
• Tanowitz HB, Kaul DK, Chen B, Morris SA, Factor SM, Weiss LM, Wittner M, et al. 1996. Compromised microcirculation in acute murine Trypanosoma cruzi infection. J Parasitol 82:124–130.
   PubMed Web of Science ®Google Scholar
• Teng KK, Felice S, Kim T, Hempstead BL. 2010. Understanding proneurotrophin actions: recent advances and challenges. Dev Neurobiol 70:350–359.
   PubMed Web of Science ®Google Scholar
• Zhou S, Cao JM, Swissa M, Gonzalez-Gomez I, Chang CM, Chien KAI, Miyauchi Y, et al. 2004. Low-affinity nerve growth factor receptor p75NTR immunoreactivity in the myocardium with sympathetic hyperinnervation. J Cardiovasc Electrophysiol 15:430–437.
   PubMed Web of Science ®Google Scholar