Tri-block co-polymer nanocarriers for enhancement of oral delivery of felodipine: preparation, in vitro characterization and ex vivo permeation

References

• Abdelbary G, Makhlouf A. (2014). Adoption of polymeric micelles to enhance the oral bioavailability of dexibuprofen: formulation, in-vitro evaluation and in-vivo pharmacokinetic study in healthy human volunteers. Pharm Dev Technol 19:717–27
   PubMed Web of Science ®Google Scholar
• Abdelbary GA, Tadros MI. (2013). Brain targeting of olanzapine via intranasal delivery of core-shell difunctional block copolymer mixed nanomicellar carriers: in vitro characterization, ex vivo estimation of nasal toxicity and in vivo biodistribution studies. Int J Pharm 452:300–10
   PubMed Web of Science ®Google Scholar
• Aburahma MH, Abdelbary GA. (2012). Novel diphenyl dimethyl bicarboxylate provesicular powders with enhanced hepatocurative activity: preparation, optimization, in vitro/in vivo evaluation. Int J Pharm 422:139–50
   PubMed Web of Science ®Google Scholar
• Alexandridis P, Athanassiou V, Fukuda S, Hatton T. (1994). Surface activity of poly (ethylene oxide)-block-poly (propylene oxide)-block-poly (ethylene oxide) copolymers. Langmuir 10:2064–612
   Web of Science ®Google Scholar
• Allen TM, Cullis PR. (2004). Drug delivery systems: entering the mainstream. Science 303:1818–22
   PubMed Web of Science ®Google Scholar
• Araujo J, Vega E, Lopes C, et al. (2009). Effect of polymer viscosity on physicochemical properties and ocular tolerance of FB-loaded PLGA nanospheres. Colloids Surf B Biointerfaces 72:48–56
   PubMed Web of Science ®Google Scholar
• Armstrong NA. (2006). Designs for mixtures. Pharmaceutical experimental design and interpretation. Boca Raton (FL): CRC Press, Taylor & Francis Group, Informa Healthcare
   Google Scholar
• Bae Y, Kataoka K. (2009). Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers. Adv Drug Deliv Rev 61:768–84
   PubMed Web of Science ®Google Scholar
• Barlow RJ, Zimmerman S, Khougaz K, Eisenberg A. (1996). Phase separation of micellar solutions at extreme dilution: a study of polystyrene-b-poly(sodium acrylate) micelles in aqueous NaCl solutions J Polym Sci Part B: Polym Phys 34:1197–212
   Web of Science ®Google Scholar
• Basalious EB, Shamma RN. (2015). Novel self-assembled nano-tubular mixed micelles of Pluronics P123, Pluronic F127 and phosphatidylcholine for oral delivery of nimodipine: In vitro characterization, ex vivo transport and in vivo pharmacokinetic studies. Int J Pharm 493:347–56
   PubMed Web of Science ®Google Scholar
• Bikiaris D, Papageorgiou GZ, Stergiou A, et al. (2005). Physicochemical studies on solid dispersions of poorly water-solubledrugs: evaluation of capabilities and limitations of thermal analysis techniques. Thermochim Acta 439:58–67
   Web of Science ®Google Scholar
• Bolton S. (1997). Pharmaceutical statistics; practical and clinical application. New York, USA: Marcel Dekker Inc
   Google Scholar
• Causse J, Lagerge S, de Menorval LC, Faure S. (2006). Micellar solubilization of tributylphosphate in aqueous solutions of Pluronic block copolymers. Part II. Structural characterization inferred by 1H NMR. J Colloid Interface Sci 300:724–34
   PubMed Web of Science ®Google Scholar
• Chiappetta DA, Sosnik A. (2007). Poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles as drug delivery agents: improved hydrosolubility, stability and bioavailability of drugs. Eur J Pharm Biopharm 66:303–17
   PubMed Web of Science ®Google Scholar
• Derringer G, Suich R. (1980). Simultaneous optimization of several response variables. J Qual Technol 12:214–19
   Web of Science ®Google Scholar
• Dixit M, Kini AG, Kulkarni PK. (2011). Enhancing solubility and dissolution of celecoxib by spray drying using Pluronic® F 127. Ind J Pharm Educ Res 45:346–52
   Web of Science ®Google Scholar
• Francis M, Cristea M, Winnik F. (2004). Polymeric micelles for oral drug delivery: why and how?. Pure Appl Chem 76:1321–35
   Web of Science ®Google Scholar
• Gao Y, Li LB, Zhai G. (2008). Preparation and characterization of Pluronic/TPGS mixed micelles for solubilization of camptothecin. Colloids Surf B Biointerfaces 64:194–9
   PubMed Web of Science ®Google Scholar
• Gao ZG, Fain HD, Rapoport N. (2005). Controlled and targeted tumor chemotherapy by micellar-encapsulated drug and ultrasound. J Control Release 102:203–22
   PubMed Web of Science ®Google Scholar
• Gillmans AG, Hardman JG, Limbird LE. (2006). Goodman and Gillman’s: the pharmacological basis of therapeutics. New York: McGraw Hill
   Google Scholar
• Gonnissen Y, Goncalves SI, De Geest BG, et al. (2008). Process design applied to optimise a directly compressible powder produced via a continuous manufacturing process. Eur J Pharm Biopharm 68:760–70
   PubMed Web of Science ®Google Scholar
• González AG. (1998). Two level factorial experimental designs based on multiple linear regression models: a tutorial digest illustrated by case studies. Anal Chim Acta 360:227–41
   Web of Science ®Google Scholar
• Guan J, Zhou L, Nie S, et al. (2010). A novel gastric-resident osmotic pump tablet: in vitro and in vivo evaluation. Int J Pharm 383:30–6
   PubMed Web of Science ®Google Scholar
• Habib BA, AbouGhaly MH. (2016). Combined mixture-process variable approach: a suitable statistical tool for nanovesicular systems optimization. Expert Opin Drug Deliv 13:777–88
   PubMed Web of Science ®Google Scholar
• Huang YB, Tsai YH, Yang WC, et al. (2004). Once-daily propranolol extended-release tablet dosage form: formulation design and in vitro/in vivo investigation. Eur J Pharm Biopharm 58:607–14
   PubMed Web of Science ®Google Scholar
• Huh KM, Lee SC, Cho YW, et al. (2005). Hydrotropic polymer micelle system for delivery of paclitaxel. J Control Release 101:59–68
   PubMed Web of Science ®Google Scholar
• Jones M, Leroux J. (1999). Polymeric micelles – a new generation of colloidal drug carriers. Eur J Pharm Biopharm 48:101–11
   PubMed Web of Science ®Google Scholar
• Kabanov AV, Alakhov VY. (2002). Pluronic block copolymers in drug delivery: from micellar nanocontainers to biological response modifiers. Crit Rev Ther Drug Carrier Syst 19:1–72
   PubMed Web of Science ®Google Scholar
• Kabanov AV, Chekhonin VP, Alakhov V, et al. (1989). The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles. Micelles as microcontainers for drug targeting. FEBS Lett 258:343–5
   PubMed Web of Science ®Google Scholar
• Kataoka K, Kwon GS, Yokoyama M, et al. (1993). Block copolymer micelles as vehicles for drug delivery. J. Control Release 24:119–32
   Web of Science ®Google Scholar
• Kim MS, Kim JS, You YH, et al. (2007). Development and optimization of a novel oral controlled delivery system for tamsulosin hydrochloride using response surface methodology. Int J Pharm 341:97–104
   PubMed Web of Science ®Google Scholar
• Kulthe SS, Inamdar NN, Choudhari YM, et al. (2011). Mixed micelle formation with hydrophobic and hydrophilic Pluronic block copolymers: implications for controlled and targeted drug delivery. Colloids Surf B Biointerfaces 88:691–6
   PubMed Web of Science ®Google Scholar
• Kwon GS, Kataoka K. (1995). Block copolymer micelles as long-circulating drug vehicles. Adv. Drug Deliv Rev 16:295–309
   Web of Science ®Google Scholar
• Kwon GS, Okano T. (1996). Polymeric micelles as new drug carriers. Adv Drug Deliv Rev 21:107–16
   Web of Science ®Google Scholar
• Lee ES, Oh YT, Youn YS, et al. (2011). Binary mixing of micelles using Pluronics for a nano-sized drug delivery system. Colloids Surf B Biointerfaces 82:190–5
   PubMed Web of Science ®Google Scholar
• Lee SC, Huh KM, Lee J, et al. (2007). Hydrotropic polymeric micelles for enhanced paclitaxel solubility: in vitro and in vivo characterization. Biomacromolecules 8:202–8
   PubMed Web of Science ®Google Scholar
• Lee SC, Kim C, Kwon IC, et al. (2003). Polymeric micelles of poly(2-ethyl-2-oxazoline)-block-poly(epsilon-caprolactone) copolymer as a carrier for paclitaxel. J Control Release 89:437–46
   PubMed Web of Science ®Google Scholar
• Mallipeddi R, Saripella KK, Neau SH. (2010). Use of coarse ethylcellulose and PEO in beads produced by extrusion-spheronization. Int J Pharm 385:53–65
   PubMed Web of Science ®Google Scholar
• Manet S, Lecchi A, Imperor-Clerc M, et al. (2011). Structure of micelles of a nonionic block copolymer determined by SANS and SAXS. J Phys Chem B 115:11318–29
   PubMed Web of Science ®Google Scholar
• Montgomery DC. (2009). Design and analysis of experiments. New York (NY): John Wiley & Sons Inc
   Google Scholar
• Nishiyama N, Kataoka K. (2006). Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery. Pharmacol Ther 112:630–48
   PubMed Web of Science ®Google Scholar
• Nour SA, Abdelmalak NS, Naguib MJ, et al. (2016). Intranasal brain-targeted clonazepam polymeric micelles for immediate control of status epilepticus: in vitro optimization, ex vivo determination of cytotoxicity, in vivo biodistribution and pharmacodynamics studies. Drug Deliv 23:3681–95
   PubMed Web of Science ®Google Scholar
• Ribeiro A, Sandez-Macho I, Casas M, et al. (2013). Poloxamine micellar solubilization of alpha-tocopherol for topical ocular treatment. Colloids Surf B Biointerfaces 103:550–7
   PubMed Web of Science ®Google Scholar
• Ribeiro A, Sosnik A, Chiappetta DA, et al. (2012). Single and mixed poloxamine micelles as nanocarriers for solubilization and sustained release of ethoxzolamide for topical glaucoma therapy. J R Soc Interface 9:2059–69
   PubMed Web of Science ®Google Scholar
• Sakai T, Kurosawa H, Okada T, Mishima S. (2011). Vesicle formation in mixture of a PEO–PPO–PEO block copolymer (Pluronic P123) and a nonionic surfactant (Span 65) in water. Colloids Surf A: Physicochem Eng Aspects 389:82–9
   Web of Science ®Google Scholar
• Salama AH, Shamma RN. (2015). Tri/tetra-block co-polymeric nanocarriers as a potential ocular delivery system of lornoxicam: in-vitro characterization, and in-vivo estimation of corneal permeation. Int J Pharm 492:28–39
   PubMed Web of Science ®Google Scholar
• Savolainen M, Khoo C, Glad H, et al. (2002). Evaluation of controlled-release polar lipid microparticles. Int J Pharm 244:151–61
   PubMed Web of Science ®Google Scholar
• Shah U, Joshi G, Sawant K. (2014). Improvement in antihypertensive and antianginal effects of felodipine by enhanced absorption from PLGA nanoparticles optimized by factorial design. Mater Sci Eng C Mater Biol Appl 35:153–63
   PubMed Web of Science ®Google Scholar
• Sjostrom B, Bergenstahl B, Kronberg B. (1993). A method for the preparation of submicron particles of sparingly water-soluble drugs by precipitation in oil-in-water emulsions. II: influence of the emulsifier, the solvent, and the drug substance. J Pharm Sci 82:584–9
   PubMed Web of Science ®Google Scholar
• Song Y, Tian Q, Huang Z, et al. (2014). Self-assembled micelles of novel amphiphilic copolymer cholesterol-coupled F68 containing cabazitaxel as a drug delivery system. Int J Nanomed 9:2307–17
   PubMed Web of Science ®Google Scholar
• Staessen JA, Wang JG, Thijs L. (2003). Cardiovascular prevention and blood pressure reduction: a quantitative overview updated until 1 March 2003. J Hypertens 21:1055. 76
   PubMed Web of Science ®Google Scholar
• Todd PA, Faulds D. (1992). Felodipine. A review of the pharmacology and therapeutic use of the extended release formulation in cardiovascular disorders. Drugs 44:251–77
   PubMed Web of Science ®Google Scholar
• United States Pharmacopeia and National Formulary (USP38-NF33). Rockville, MD: United States Pharmacopeial Convention; 2015. Available from: http://www.uspnf.com/uspnf/pub/index?usp=38&nf=33&s=2&officialOn=December%201,%202015
   Google Scholar
• Wei Z, Hao J, Yuan S, et al. (2009). Paclitaxel-loaded Pluronic P123/F127 mixed polymeric micelles: formulation, optimization and in vitro characterization. Int J Pharm 376:176–85
   PubMed Web of Science ®Google Scholar
• Zhang X, Jackson J, Burt H. (1996). Development of amphiphilic diblock copolymers as micellar carriers of taxol. Int J Pharm 132:195–206
   Web of Science ®Google Scholar
• Zhang Y, Wang X, Lin X, et al. (2010). High azithromycin loading powders for inhalation and their in vivo evaluation in rats. Int J Pharm 395:205–14
   PubMed Web of Science ®Google Scholar