Co-delivery of gambogenic acid and VEGF-siRNA with anionic liposome and polyethylenimine complexes to HepG2 cells

References

• Babu, A., et al., 2017. Combinatorial therapeutic approaches with RNAi and anticancer drugs using nanodrug delivery systems. Drug development and industrial pharmacy, 43 (9), 1391–1401.
   PubMed Web of Science ®Google Scholar
• Bruno, K., et al., 2011. Using drug-excipient interactions for siRNA delivery. Advanced drug delivery reviews, 63 (13), 1210–1226.
   PubMed Web of Science ®Google Scholar
• Chen, W., et al., 2014. Co-delivery of doxorubicin and siRNA with reduction and pH dually sensitive nanocarrier for synergistic cancer therapy. Small (Weinheim an Der Bergstrasse, Germany), 10 (13), 2678–2687.
   PubMed Web of Science ®Google Scholar
• Düzgüneş, N., et al., 1985. Proton-induced fusion of oleic acid-phosphatidylethanolamine liposomes. Biochemistry, 24 (13), 3091–3098.
   PubMed Web of Science ®Google Scholar
• Ducat, E., et al., 2011. Nuclear delivery of a therapeutic peptide by long circulating pH-sensitive liposomes: benefits over classical vesicles. International journal of pharmaceutics, 420 (2), 319–332.
   PubMed Web of Science ®Google Scholar
• Ferrara, N., et al., 2012. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochemical and biophysical research communications, 161, 851–858.
   Google Scholar
• Guo, W., et al., 2000. Efficient gene delivery using anionic liposome-complexed polyplexes (LPDII). Bioscience reports, 20 (5), 419–432.
   PubMed Web of Science ®Google Scholar
• Guo, W., et al., 2002. Characterization of a novel diolein-based LPDII vector for gene delivery. Journal of controlled release, 83 (1), 121–132.
   PubMed Web of Science ®Google Scholar
• Ge, Y.L., et al., 2009. The mechanisms on apoptosis by inhibiting VEGF expression in human breast cancer cells. International immunopharmacology, 9 (4), 389–395.
   PubMed Web of Science ®Google Scholar
• Hecker, J.G., et al., 2016. Non-viral, lipid-mediated DNA and mRNA gene therapy of the central nervous system (CNS): chemical-based transfection. Methods in Molecular Biology, 1382, 307–324.
   PubMedGoogle Scholar
• Ho, W., et al., 2016. Biomaterials in siRNA delivery: a comprehensive review. Advanced healthcare materials, 5 (21), 2715–2731.
   PubMed Web of Science ®Google Scholar
• Huang, X., et al., 2013. Solid lipid nanoparticles as delivery systems for Gambogenic acid. Colloids and surfaces b, biointerfaces, 102, 391–397.
   PubMed Web of Science ®Google Scholar
• Itaka, K., et al., 2009. Recent development of nonviral gene delivery systems with virus-like structures and mechanisms. European journal of pharmaceutics and biopharmaceutics, 71 (3), 475–483.
   PubMed Web of Science ®Google Scholar
• Jin, L., et al., 2018. Polyethylenimine-mediated CCR5 gene knockout using transcription activator-like effector nucleases. Journal of biomedical nanotechnology, 14 (3), 546–552.
   PubMed Web of Science ®Google Scholar
• Kim, W.J., et al., 2007. Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy. Journal of controlled release, 118 (3), 357–363.
   PubMed Web of Science ®Google Scholar
• Ko, H., et al., 2016. Tumor microenvironment-specific nanoparticles activatable by stepwise transformation. Journal of controlled release, 234, 68–78.
   PubMed Web of Science ®Google Scholar
• Lin, T.Y., et al., 2013. PEGylated non-ionic surfactant vesicles as drug delivery systems for Gambogenic acid. Drug delivery, 20 (7), 277–284.
   PubMed Web of Science ®Google Scholar
• Lin, T.Y., et al., 2017. Long circulation nanostructured lipid carriers for gambogenic acid: formulation design, characterization, and pharmacokinetic. Xenobiotica, 47 (9), 793–799.
   PubMed Web of Science ®Google Scholar
• Li, Y., et al., 2016. Co-delivery of siRNA and hypericin into cancer cells by hyaluronic acid modified PLGA-PEI nanoparticles. Drug development and industrial pharmacy, 42 (5), 737–746.
   PubMed Web of Science ®Google Scholar
• Lu, G.B., et al., 1984. Isolation and structure of neo-gambogic acid from Gamboge (Garcinia hanburryi). Yao xue xue bao, 19 (8), 636–639.
   PubMedGoogle Scholar
• Luo, Q., et al., 2015. A novel glyceryl monoolein-bearing cubosomes for gambogenic acid: preparation, cytotoxicity and intracellular uptake. International journal of pharmaceutics, 493 (1–2), 30–39.
   PubMed Web of Science ®Google Scholar
• Malhotra, M., et al., 2009. Ultrafine chitosan nanoparticles as an efficient nucleic acid delivery system targeting neuronal cells. Drug development and industrial pharmacy, 35 (6), 719–726.
   PubMed Web of Science ®Google Scholar
• Mintzer, M.A., et al., 2009. Nonviral vectors for gene delivery. Chemical reviews, 109 (2), 259–302.
   PubMed Web of Science ®Google Scholar
• Misra, R., et al., 2010. Cancer nanotechnology: application of nanotechnology in cancer therapy. Drug Discovery Today, 15 (19–20), 842–850.
   PubMed Web of Science ®Google Scholar
• Miura, H., et al., 1997. Increased expression of vascular endothelial growth factor in human hepatocellular carcinoma. Journal of hepatology, 27 (5), 854–861.
   PubMed Web of Science ®Google Scholar
• Mok, H., et al., 2010. pH-Sensitive siRNA nanovector for targeted gene silencing and cytotoxic effect in cancer cells. Molecular pharmaceutics, 7 (6), 1930–1939.
   PubMed Web of Science ®Google Scholar
• Peng, H., et al., 2016. Apatinib inhibits VEGF signaling and promotes apoptosis in intrahepatic cholangiocarcinoma. Oncotarget, 7 (13), 17220–17229.
   PubMedGoogle Scholar
• Peterson, J.E., 2012. VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients. Angiogenesis, 15 (2), 265–273.
   PubMed Web of Science ®Google Scholar
• Pollard, H., et al., 1998. Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. The journal of biological chemistry, 273 (13), 7507–7511.
   PubMed Web of Science ®Google Scholar
• Ponnappa, B.C., et al., 2005. Inhibition of tumor necrosis factor alpha secretion and prevention of liver injury in ethanol-fed rats by antisense oligonucleotides. Biochemical pharmacology, 69 (4), 569–577.
   PubMed Web of Science ®Google Scholar
• Rak, M., et al., 2016. Efficient and non-toxic gene delivery by anionic lipoplexes based on polyprenyl ammonium salts and their effects on cell physiology. The journal of gene medicine, 18 (11–12), 331–342.
   PubMed Web of Science ®Google Scholar
• Schäfer, J., et al., 2010. Liposome-polyethylenimine complexes for enhanced DNA and siRNA delivery. Biomaterials, 31 (26), 6892–6900.
   PubMed Web of Science ®Google Scholar
• Shi, G., et al., 2002. Efficient intracellular drug and gene delivery using folate receptor-targeted pH-sensitive liposomes composed of cationic/anionic lipid combinations. Journal of controlled release, 80 (1–3), 309–319.
   PubMed Web of Science ®Google Scholar
• Singhal, S., et al., 2010. Nanotechnology applications in surgical oncology. Annual review of medicine, 61, 359–373.
   PubMed Web of Science ®Google Scholar
• Steffes, V.M., et al., 2017. Distinct solubility and cytotoxicity regimes of paclitaxel-loaded cationic liposomes at low and high drug content revealed by kinetic phase behavior and cancer cell viability studies. Biomaterials, 145, 242–255.
   PubMed Web of Science ®Google Scholar
• Su, J., et al., 2014. Synergistic effects of 5-fluorouracil and gambogenic acid on A549 cells: activation of cell death caused by apoptotic and necroptotic mechanisms via the ROS-mitochondria pathway. Biological & pharmaceutical bulletin, 37 (8), 1259–1268.
   PubMed Web of Science ®Google Scholar
• Sun, D., et al., 2017. Cationic liposome co-encapsulation of SMAC mimetic and zVAD using a novel lipid bilayer fusion loaded with MLKL-pDNA for tumour inhibition in vivo. Journal of drug targeting, 11, 1–10.
   Google Scholar
• Srinivasan, C., et al., 2009. Optimization and characterization of anionic lipoplexes for gene delivery. Journal of controlled release, 136 (1), 62–70.
   PubMed Web of Science ®Google Scholar
• Wang, D., et al., 2017. Codelivery of doxorubicin and MDR1-siRNA by mesoporous silica nanoparticles-polymerpolyethylenimine to improve oral squamous carcinoma treatment. International journal of nanomedicine, 13, 187–198.
   PubMed Web of Science ®Google Scholar
• Xu, C., et al., 2011. RNA interference as therapeutics for hepatocellular carcinoma. Recent patents on anti-cancer drug discovery, 6 (1), 106–115.
   PubMed Web of Science ®Google Scholar
• Yao, Y., et al., 2015. pH-Sensitive carboxymethyl chitosan-modified cationic liposomes for sorafenib and siRNA co-delivery. International journal of nanomedicine, 10, 6185–6197.
   PubMed Web of Science ®Google Scholar
• Yan, F., et al., 2011. Gambogenic acid mediated apoptosis through the mitochondrial oxidative stress and inactivation of Akt signaling pathway in human nasopharyngeal carcinoma CNE-1 cells. European journal of pharmacology, 652 (1–3), 23–32.
   PubMed Web of Science ®Google Scholar
• Yan, F., et al., 2012. Gambogenic acid induced mitochondrial-dependent apoptosis and referred to phospho-Erk1/2 and phospho-p38 MAPK in human hepatoma HepG2 cells. Environmental toxicology and pharmacology, 33 (2), 181–190.
   PubMed Web of Science ®Google Scholar
• Yu, Q., et al., 2014. The use of pH-sensitive functional selenium nanoparticles shows enhanced in vivo VEGF-siRNA silencing and fluorescence imaging. Nanoscale, 6 (15), 9279–9292.
   PubMed Web of Science ®Google Scholar
• Yu, X.J., et al., 2012. Gambogenic acid induces G1 arrest via GSK3β-dependent cyclin D1 degradation and triggers autophagy in lung cancer cells. Cancer letters, 322 (2), 185–194.
   PubMed Web of Science ®Google Scholar