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Original Article

Individuals with dark eyes and hair exhibit higher pain sensitivity

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Pages 21-26 | Received 12 Nov 2016, Accepted 20 Dec 2016, Published online: 16 Jan 2017

References

  • Alabas OA, Tashani OA, Tabasam G, Johnson MI. 2012. Gender role affects experimental pain responses: a systematic review with meta-analysis. Eur J Pain 16:1211–1223.
  • Bartley EJ, Fillingim RB. 2013. Sex differences in pain: a brief review of clinical and experimental findings. Br J Anaesth 111:52–58.
  • Belfer I. 2013. Nature and nurture of human pain. Scientifica (Cairo) 2013:415279.
  • Diatchenko L, Fillingim RB, Smith SB, Maixner W. 2013. The phenotypic and genetic signatures of common musculoskeletal pain conditions. Nat Rev Rheumatol 9:340–350.
  • Drewes AM, Helweglarsen S, Petersen P, Brennum J, Andreasen A, Poulsen LH, Jensen TS. 1993. McGill Pain Questionnaire Translated into Danish: experimental and clinical findings. Clin J Pain 9:80–87.
  • Jackson PL, Meltzoff AN, Decety J. 2005. How do we perceive the pain of others? A window into the neural processes involved in empathy. Neuroimage 24:771–779.
  • Jensen K, Andersen HO, Olesen J, Lindblom U. 1986. Pressure-pain threshold in human temporal region. Evaluation of a new pressure algometer. Pain 25:313–323.
  • King RA, Willaert RK, Schmidt RM, Pietsch J, Savage S, Brott MJ, Fryer JP, Summers CG, Oetting WS. 2003. MC1R mutations modify the classic phenotype of oculocutaneous albinism type 2 (OCA2). Am J Hum Genet 73:638–645.
  • Lewis GN, Heales L, Rice DA, Rome K, McNair PJ. 2012. Reliability of the conditioned pain modulation paradigm to assess endogenous inhibitory pain pathways. Pain Res Manag 17:98–102.
  • Liem EB, Lin CM, Suleman MI, Doufas AG, Gregg RG, Veauthier JM, Loyd G, Sessler DI. 2004. Anesthetic requirement is increased in redheads. Anesthesiology 101:279–283.
  • Liem EB, Joiner TV, Tsueda K, Sessler DI. 2005. Increased sensitivity to thermal pain and reduced subcutaneous lidocaine efficacy in redheads. Anesthesiology 102:509–514.
  • Makova K, Norton H. 2005. Worldwide polymorphism at the MC1R locus and normal pigmentation variation in humans. Peptides 26:1901–1908.
  • McGrath PA. 1994. Psychological-aspects of pain perception. Arch Oral Biol 39:S55–S62.
  • Mogil JS, Wilson SG, Chesler EJ, Rankin AL, Nemmani KV, Lariviere WR, Groce MK, Wallace MR, Kaplan L, Staud R, et al. 2003. The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans. Proc Natl Acad Sci USA 100:4867–4872.
  • Mogil JS, Ritchie J, Smith SB, Strasburg K, Kaplan L, Wallace MR, Romberg RR, Bijl H, Sarton EY, Fillingim RB, Dahan A. 2005. Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans. J Med Genet 42:583–587.
  • Morris MC, Walker L, Bruehl S, Hellman N, Sherman AL, Rao U. 2015. Race effects on temporal summation to heat pain in youth. Pain 156:917–922.
  • Oertel BG, Lotsch J. 2013. Clinical pharmacology of analgesics assessed with human experimental pain models: bridging basic and clinical research. Brit J Pharmacol 168:534–553.
  • Olesen AE, Andresen T, Staahl C, Drewes AM. 2012. Human experimental pain models for assessing the therapeutic efficacy of analgesic drugs. Pharmacol Rev 64:722–779.
  • Reddy KSK, Naidu MUR, Rani PU, Rao TRK. 2012. Human experimental pain models: a review of standardized methods in drug development. J Res Med Sci 17:587–595.
  • Ruscheweyh R, Kuhnel M, Filippopulos F, Blum B, Eggert T, Straube A. 2014. Altered experimental pain perception after cerebellar infarction. Pain 155:1303–1312.
  • Schork NJ. 2015. Personalized medicine: time for one-person trials. Nature 520:609–611.
  • Sessler DI. 2015. Red hair and anesthetic requirement. Can J Anesth 62:333–337.
  • Tan JCG, Armstrong NJ, Yuan FF, Flower RL, Dyer WB. 2015. Identification of genetic polymorphisms that predict responder/non-responder profiles to the RhD antigen. Mol Immunol 68:628–633.
  • Teng C, Belfer I. 2014. Correlation between eye color and pain phenotypes in healthy women. J Pain 15:S25–S25.
  • Vercellini P, Buggio L, Somigliana E, Dridi D, Marchese MA, Vigano P. 2014. “Behind blue eyes”†: the association between eye colour and deep infiltrating endometriosis. Hum Reprod 29:2171–2175.
  • Vigil JM, Torres D, Wolff A, Hughes K. 2014. Exposure to virtual social stimuli modulates subjective pain reports. Pain Res Manag 19:e103–e108.
  • Young EE, Lariviere WR, Belfer I. 2012. Genetic basis of pain variability: recent advances. J Med Genet 49:1–9.

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