Advanced search
Publication Cover
Baylor University Medical Center Proceedings
The peer-reviewed journal of Baylor Scott & White Health
Volume 35, 2022 - Issue 5
Submit an article Journal homepage
119
Views
0
CrossRef citations to date
0
Altmetric
Original Research

Sugammadex versus neostigmine for routine reversal of neuromuscular blockade and the effect on perioperative efficiency

Andrew P. Mossa Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, AlabamaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-7132-7575
, MDORCID Icon,
Mark F. Powella Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama
, MD,
Charity J. Morganb Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama
, PhD &
Michelle D. Tubinisa Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama
, MD
Pages 599-603 | Received 18 Mar 2022, Accepted 09 May 2022, Published online: 06 Jun 2022

  • Merck. How are you dosing BRIDION? 2022. https://www.merckconnect.com/static/pdf/bridion-sugammadex-dosing-considerations.pdf.
  • Van Pelt M, Chitilian HV, Eikerman M. Multi-faceted initiative designed to improve safety of neuromuscular blockade. APSF News. 2016;3(3):51–52. https://www.apsf.org/wp-content/uploads/newsletters/2016/February/pdf/APSF201602.pdf
  • Austin PC. An introduction to propensity score methods for reducing the effects of confounding in observational studies. Multivariate Behav Res. 2011;46(3):399–424. doi:10.1080/00273171.2011.568786.
  • Murphy GS, Brull SJ. Residual neuromuscular block: lessons unlearned. Part I: definitions, incidence, and adverse physiologic effects of residual neuromuscular block. Anesth Analg. 2010;111(1):120–128. doi:10.1213/ANE.0b013e3181da832d.
  • Hristovska AM, Duch P, Allingstrup M, Afshari A. Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults. Cochrane Database Syst Rev. 2017;8(8):CD012763. doi:10.1002/14651858.CD012763.
  • Nair VP, Hunter JM. Anticholinesterases and anticholinergic drugs. Crit Care Pain. 2004;4:164–168.
  • Paton F, Paulden M, Chambers D, et al. Sugammadex compared with neostigmine/glycopyrrolate for routine reversal of neuromuscular block: a systematic review and economic evaluation. Br J Anaesth. 2010;105(5):558–567. doi:10.1093/bja/aeq269.
  • Zaouter C, Mion S, Palomba A, Hemmerling T. A short update on sugammadex with a special focus on economic assessment of its use in North America. J Anesth Clin Res. 2017;08(07):740. doi:10.4172/2155-6148.1000740.
  • Hurford WE, Welge JA, Eckman MH. Sugammadex versus neostigmine for routine reversal of rocuronium block in adult patients: a cost analysis. J Clin Anesth. 2020;67:110027. doi:10.1016/j.jclinane.2020.110027.
  • Deyhim N, Beck A, Balk J, Liebl MG. Impact of sugammadex versus neostigmine/glycopyrrolate on perioperative efficiency. CEOR. 2020;12:69–79. doi:10.2147/CEOR.S221308.
  • Koo B, Oh A, Na H, et al. Effects of depth of neuromuscular block on surgical conditions during laparoscopic colorectal surgery: a randomised controlled trial. Anaesthesia. 2018;73(9):1090–1096. doi:10.1111/anae.14304.
  • Carron M, Baratto F, Zarantonello F, Ori C. Sugammadex for reversal of neuromuscular blockade: a retrospective analysis of clinical outcomes and cost-effectiveness in a single center. CEOR. 2016;8:43–52. doi:10.2147/CEOR.S100921.
  • Min BH, Oh TK, Song IA, Jeon YT. Comparison of the effects of sugammadex and neostigmine on hospital stay in robot-assisted laparoscopic prostatectomy: a retrospective study. BMC Anesthesiol. 2020;20(1):178. doi:10.1186/s12871-020-01088-6.
  • Ledowski T, Falke L, Johnston F, et al. Retrospective investigation of postoperative outcome after reversal of residual neuromuscular blockade: sugammadex, neostigmine or no reversal. Eur J Anaesthesiol. 2014;31(8):423–429. doi:10.1097/EJA.0000000000000010.
  • Ledowski T, Hillyard S, Kozman A, et al. Unrestricted access to sugammadex: impact on neuromuscular blocking agent choice, reversal practice and associated healthcare costs. Anaesth Intens Care. 2012;40(2):340–343. doi:10.1177/0310057X1204000219.
  • Abad-Gurumeta A, Ripollés-Melchor J, Casans-Francés R, et al; Evidence Anaesthesia Review Group. A systematic review of sugammadex vs neostigmine for reversal of neuromuscular blockade. Anaesthesia. 2015;70(12):1441–1452. doi:10.1111/anae.13277.
  • Butterly A, Bittner E, George E, Sandberg W, Eikermann M, Schmidt U. Postoperative residual curarization from intermediate-acting neuromuscular blocking agents delays recovery room discharge. Br J Anaesth. 2010;105(3):304–309. doi:10.1093/bja/aeq157.
  • Li G, Freundlich RE, Gupta RK, et al. Postoperative pulmonary complications' association with sugammadex versus neostigmine: a retrospective registry analysis. Anesthesiology. 2021;134(6):862–873. doi:10.1097/ALN.0000000000003735.
  • Girotto JA, Koltz PF, Drugas G. Optimizing your operating room: or, why large, traditional hospitals don't work. Int J Surg. 2010;8(5):359–367. doi:10.1016/j.ijsu.2010.05.002.
  • Childers CP, Maggard-Gibbons M. Understanding costs of care in the operating room. JAMA Surg. 2018;153(4):e176233–e176233. doi:10.1001/jamasurg.2017.6233.
  • Thilen SR, Weigel WA. Sugammadex: a costly simple solution that is not really solving the problem. Anesth Analg. 2020;131(2):e73–e74. doi:10.1213/ANE.0000000000004761.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.