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Baylor University Medical Center Proceedings
The peer-reviewed journal of Baylor Scott & White Health
Volume 35, 2022 - Issue 6
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Original Research

Sucrose intolerance in adults with common functional gastrointestinal symptoms

, MDORCID Icon & , MD, PhD
Pages 790-793 | Received 22 Jul 2022, Accepted 11 Aug 2022, Published online: 23 Aug 2022

  • Gericke B, Amiri M, Scott CR, Naim HY. Molecular pathogenicity of novel sucrase-isomaltase mutations found in congenital sucrase-isomaltase deficiency patients. Biochim Biophys Acta Mol Basis Dis. 2017;1863(3):817–826. doi:10.1016/j.bbadis.2016.12.017.
  • Garcia-Etxebarria K, Zheng T, Bonfiglio F, et al. Increased prevalence of rare sucrase-isomaltase pathogenic variants in irritable bowel syndrome patients. Clin Gastroenterol Hepatol. 2018;16(10):1673–1676. doi:10.1016/j.cgh.2018.01.047.
  • Fedewa A, Rao SS. Dietary fructose intolerance, fructan intolerance and FODMAPs. Cur Gastroenterol Rep. 2014;16(1):370. doi:10.1007/s11894-013-0370-0.
  • Gibson P, Halmos E. FODMAPs and carbohydrate intolerance. clinical and basic neurogastroenterology and motility. In Rao SSC, Lee YY, Ghoshal UC, eds. Clinical and Basic Neurogastroenterology Motility. London: Academic Press; 2020:371–386. doi:10.1016/B978-0-12-813037-7.00026-1.
  • Henström M, Diekmann L, Bonfiglio F, et al. Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome. Gut. 2018;67(2):263–270. doi:10.1136/gutjnl-2016-312456.
  • Rezaie A, Buresi M, Lembo A, et al. Hydrogen and methane-based breath testing in gastrointestinal disorders: the North American consensus. Am J Gastroenterol. 2017;112(5):775–784. doi:10.1038/ajg.2017.46.
  • Aerodiagnostics/QuinTron. Breath-tests and digestive problems. 2015. https://aerodiagnostics.com/docs/Sucroseinst_Version2.pdf.
  • Commonwealth Diagnostics International. 7 simple steps: hydrogen & methane breath test for sucrose malabsorption. September 9, 2020. https://commdx.com/wp-content/uploads/2020/12/CDI-Instructional-Guide-Sucrose.pdf.
  • YouTube. Sucrose intolerance C13 breath test—how-to instructional video. February 21 2019. www.youtube.com/watch?v=lE43P7nlgoU.
  • Metabolic Solutions. Sucrose breath test. 2014. www.metsol.com/wp-content/uploads/2014/04/Sucrose-Breath-Test.pdf.
  • Pelton N, Tran C, Leo A, et al. The reproducibility of the 13C-sucrose breath test in children and adults [White paper]. QOL Medical; 2009.
  • Ghoshal UC. How to interpret hydrogen breath tests. J Neurogastroenterol Motil. 2011;17(3):312–317. doi:10.5056/jnm.2011.17.3.312.
  • Gericke B, Amiri M, Naim HY. The multiple roles of sucrase-isomaltase in the intestinal physiology. Mol Cell Pediatr. 2016;3(1):2. doi:10.1186/s40348-016-0033-y.
  • Robayo-Torres CC, Quezada-Calvillo R, Nichols BL. Disaccharide digestion: clinical and molecular aspects. Clin Gastroenterol Hepatol. 2006;4(3):276–287. doi:10.1016/j.cgh.2005.12.023.
  • Nichols BL Jr, Adams B, Roach CM, Ma CX, Baker SS. Frequency of sucrase deficiency in mucosal biopsies. J Pediatr Gastroenterol Nutr. 2012;55(Supplement 2):S28–S30. doi:10.1097/01.mpg.0000421405.42386.64.
  • Chumpitazi BP, Robayo-Torres CC, Tsai CM, et al. Yield of prospective disaccharidase testing in children with recurrent abdominal pain. Gastroenterology. 2013;144(5):S401–S402. doi:10.1016/S0016-5085(13)61477-8.
  • Viswanathan L, Kennedy K, Sharma A, Yan Y, Jimenez E, Rao SSC. Prevalence of disaccharidase deficiency in adults with unexplained gastrointestinal symptoms. J Neurogastroenterol Motil. 2020;26(3):384–390. doi:10.5056/jnm19167.
  • Zheng T, Eswaran S, Photenhauer AL, Merchant JL, Chey WD, D'Amato M. Reduced efficacy of low FODMAPs diet in patients with IBS-D carrying sucrase-isomaltase (SI) hypomorphic variants. Gut. 2020;69(2):397–398. doi:10.1136/gutjnl-2018-318036.

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