- Bláha J, Bartošová T. Epidemiology and definition of PPH worldwide. Best Pract Res Clin Anaesthesiol 2022;36(3–4):325–339. doi:10.1016/j.bpa.2022.11.001.
- Charbit B, Mandelbrot L, Samain E, et al. The decrease of fibrinogen is an early predictor of the severity of postpartum hemorrhage. J Thromb Haemost 2007;5(2):266–273. doi:10.1111/j.1538-7836.2007.02297.x.
- Collins P, Bell S, de Lloyd L, Collis R. Management of postpartum haemorrhage: from research into practice, a narrative review of the literature and the Cardiff experience. Int J Obstet Anesth. 2019;37:106–117. doi:10.1016/j.ijoa.2018.08.008.
- Collins P. Point-of-care coagulation testing for postpartum haemorrhage. Best Pract Res Clin Anaesthesiol 2022;36(3–4):383–398. doi:10.1016/j.bpa.2022.08.002.
- Collins PW, Lilley G, Bruynseels D, et al. Fibrin-based clot formation as an early and rapid biomarker for progression of postpartum hemorrhage: a prospective study. Blood 2014;124(11):1727–1736. doi:10.1182/blood-2014-04-567891.
- Bell SF, Collis RE, Pallmann P, et al. Reduction in massive postpartum haemorrhage and red blood cell transfusion during a national quality improvement project, Obstetric Bleeding Strategy for Wales, OBS Cymru: an observational study. BMC Pregnancy Childbirth. 2021;21(1):377. doi:10.1186/s12884-021-03853-y.
- Bell SF, Collis RE, Bailey C, et al. The incidence, aetiology, and coagulation management of massive postpartum haemorrhage: a two-year national prospective cohort study. Int J Obstet Anesth 2021;47:102983. doi:10.1016/j.ijoa.2021.102983.
- Collis RE, Kenyon C, Roberts TCD, McNamara H. When does obstetric coagulopathy occur and how do I manage it? Int J Obstet Anesth 2021;46:102979. doi:10.1016/j.ijoa.2021.102979.
- Lee J, Eley VA, Wyssusek KH, et al. Baseline parameters for rotational thromboelastometry (ROTEM®) in healthy women undergoing elective caesarean delivery: a prospective observational study in Australia. Int J Obstet Anesth. 2019;38:10–18. doi:10.1016/j.ijoa.2019.01.008.
- Snegovskikh D, Souza D, Walton Z, et al. Point-of-care viscoelastic testing improves the outcome of pregnancies complicated by severe postpartum hemorrhage. J Clin Anesth 2018;44:50–56. doi:10.1016/j.jclinane.2017.10.003.
- McNamara H, Kenyon C, Smith R, Mallaiah S, Barclay P. Four years’ experience of a ROTEM®-guided algorithm for treatment of coagulopathy in obstetric haemorrhage. Anaesthesia 2019;74(8):984–991. doi:10.1111/anae.14628.
- Mallaiah S, Barclay P, Harrod I, Chevannes C, Bhalla A. Introduction of an algorithm for ROTEM-guided fibrinogen concentrate administration in major obstetric haemorrhage. Anaesthesia 2015;70(2):166–175. doi:10.1111/anae.12859.
- Collins P, Abdul-Kadir R, Thachil J; Subcommittees on Women’s Health Issues in Thrombosis and Haemostasis and on Disseminated Intravascular Coagulation. Management of coagulopathy associated with postpartum hemorrhage: guidance from the SSC of the ISTH. J Thromb Haemost. 2016;14(1):205–210. doi:10.1111/jth.13174.
- Bell SF, Roberts TCD, Pereira JFM, et al. The sensitivity and specificity of ROTEM to detect coagulopathy during moderate and severe postpartum haemorrhage: a prospective observational study. Int J Obstet Anesth 2021;49:103238. doi:10.1016/j.ijoa.2021.103238.
- Reale SC, Farber MK. Point-of-care coagulation testing for obstetric hemorrhage: time for a theranostic approach? Int J Obstet Anesth 2019;38:1–3. doi:10.1016/j.ijoa.2019.04.001.
- Huissoud C, Carrabin N, Benchaib M, et al. Coagulation assessment by rotation thrombelastometry in normal pregnancy. Thromb Haemostasis 2009;101(04):755–761. doi:10.1160/TH08-06-0386.
- Armstrong S, Fernando R, Ashpole K, Simons R, Columb M. Assessment of coagulation in the obstetric population using ROTEM® thromboelastometry. Int J Obstet Anesth 2011;20(4):293–298. doi:10.1016/j.ijoa.2011.05.004.
- Lang T, Bauters A, Braun SL, et al. Multi-centre investigation on reference ranges for ROTEM thromboelastometry. Blood Coagul Fibrin 2005;16(4):301–10. doi:10.1097/01.mbc.0000169225.31173.19.
- Creanga AA, Catalano PM, Bateman BT. Obesity in pregnancy. New Engl J Med 2022;387(3):248–259. doi:10.1056/nejmra1801040.
- National Health and Nutrition Examination Survey. NHANES interactive data visualizations. Accessed May 21, 2023. https://www.cdc.gov/nchs/nhanes/visualization/index.htm.
- Horowitz GL. Estimating reference intervals. Am J Clin Pathol 2010;133(2):175–177. doi:10.1309/ajcpq4n7brzqvhal.
- Horowitz GL. Reference intervals: practical aspects. EJIFCC. 2008;19(2):95–105.
- de Lange NM, van Rheenen-Flach LE, Lancé MD, et al. Peri-partum reference ranges for ROTEM® thromboelastometry. Br J Anaesth 2014;112(5):852–859. doi:10.1093/bja/aet480.
- Butwick AJ, Abreo A, Bateman BT, et al. Effect of maternal body mass index on postpartum hemorrhage. Anesthesiology 2018;128(4):774–783. doi:10.1097/aln.0000000000002082.
- Flegal KM, Kruszon-Moran D, Carroll MD, Fryar CD, Ogden CL. Trends in obesity among adults in the United States, 2005 to 2014. JAMA 2016;315(21):2284–2291. doi:10.1001/jama.2016.6458.
- Duraj L, Stasko J, Hasko M, et al. Monitoring of hemostasis by rotational thrombelastometry during normal pregnancy and postpartum. Acta Med Martiniana 2015;15(2):5–12. doi:10.1515/acm-2015-0006.
- Bryant A, Mhyre JM, Leffert LR, et al. The association of maternal race and ethnicity and the risk of postpartum hemorrhage. Anesth Analges. 2012;115(5):1127–1136. doi:10.1213/ane.0b013e3182691e62.
- Blondon M, Harrington LB, Righini M, et al. Racial and ethnic differences in the risk of postpartum venous thromboembolism: a population-based, case-control study. J Thromb Haemost 2014;12(12):2002–2009. doi:10.1111/jth.12747.
- Sumner RC, Bennett R, Creaven A-M, Gallagher S. Unemployment, employment precarity, and inflammation. Brain Behav Immun 2019;83:303–308. doi:10.1016/j.bbi.2019.10.013.
- Murray EKI, Murphy MSQ, Smith GN, Graham CH, Othman M. Thromboelastographic analysis of haemostasis in preeclamptic and normotensive pregnant women. Blood Coagul Fibrin 2018;29(6):567–572. doi:10.1097/mbc.0000000000000759.
- Morgan ES, Wilson E, Melody T, et al. An observational study of haemostatic changes, leptin and soluble endoglin during pregnancy in women with different BMIs. Blood Coagul Fibrin 2017;28(1):50–55. doi:10.1097/mbc.0000000000000535.
- Morgan ES, Wilson E, Watkins T, Gao F, Hunt BJ. Maternal obesity and venous thromboembolism. Int J Obstet Anesth 2012;21(3):253–263. doi:10.1016/j.ijoa.2012.01.002.
- O’Keefe D, Lim HY, Tham J, Ho P, Hui L. Assessing maternal clotting function with novel global coagulation assays: A prospective pilot study. Int J Lab Hematol 2021;43(3):458–467. doi:10.1111/ijlh.13389.
- Hunt BJ. The effect of BMI on haemostasis: Implications for thrombosis in women’s health. Thromb Res 2017;151(Supp 1):S53–S55. doi:10.1016/S0049-3848(17)30068-3.
- Lee J, Eley VA, Wyssusek KH, et al. The influence of obesity on coagulation in healthy term pregnancy as assessed by rotational thromboelastometry. Australian New Zealand J Obstetrics Gynaecol 2020;60(5):714–719. doi:10.1111/ajo.13141.
- Sharma SK, Philip J, Whitten CW, Padakandla UB, Landers DF. Assessment of changes in coagulation in parturients with preeclampsia using thromboelastography. Anesthesiology 1999;90(2):385–390. doi:10.1097/00000542-199902000-00009.
- Orlikowski CE, Rocke DA, Murray WB, et al. Thrombelastography changes in pre-eclampsia and eclampsia. BJA Br J Anaesth 1996;77(2):157–161. doi:10.1093/bja/77.2.157.
- Gonzalez-Fiol A, Eisenberger A. Anesthesia implications of coagulation and anticoagulation during pregnancy. Semin Perinatol 2014;38(6):370–377. doi:10.1053/j.semperi.2014.07.003.
- Haram K, Mortensen JH, Mastrolia SA, Erez O. Disseminated intravascular coagulation in the HELLP syndrome: how much do we really know? J Maternal-Fetal Neonatal Med 2016;30(7):1–10. doi:10.1080/14767058.2016.1189897.
- Andrew L, Áinle FN, Blondon M, Rodger MA, Skeith L. Preventing postpartum venous thromboembolism: A call to action to reduce undue maternal morbidity and mortality. Thromb Res 2020;193:190–197. doi:10.1016/j.thromres.2020.07.007.
- Blondon M, Harrington LB, Boehlen F, et al. Pre-pregnancy BMI, delivery BMI, gestational weight gain and the risk of postpartum venous thrombosis. Thromb Res 2016;145:151–156. doi:10.1016/j.thromres.2016.06.026.
- Gillispie-Bell V. The contrast of color: why the Black community continues to suffer health disparities. Obstetrics Gynecol 2021;137(2):220–224. doi:10.1097/aog.0000000000004226.
Baseline rotational thromboelastometry (ROTEM) values in a healthy, diverse obstetric population and parameter changes by pregnancy-induced comorbidities
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