- Lee LA, Caplan RA, Stephens LS, et al. Postoperative opioid-induced respiratory depression: a closed claims analysis. Anesthesiology. 2015;122(3):659–665. doi:10.1097/ALN.0000000000000564.
- Khanna AK, Bergese SD, Jungquist CR, et al. Prediction of opioid-induced respiratory depression on inpatient wards using continuous capnography and oximetry: an international prospective, observational trial. Anesth Analg. 2020;131(4):1012–1024. doi:10.1213/ANE.0000000000004788.
- Sun Z, Sessler DI, Dalton JE, et al. Postoperative hypoxemia is common and persistent: a prospective blinded observational study. Anesth Analg. 2015;121(3):709–715. doi:10.1213/ANE.0000000000000836.
- Weingarten TN, Herasevich V, McGlinch MC, et al. Predictors of delayed postoperative respiratory depression assessed from naloxone administration. Anesth Analg. 2015;121(2):422–429. doi:10.1213/ANE.0000000000000792.
- Chung F, Memtsoudis SG, Ramachandran SK, et al. Society of Anesthesia and Sleep Medicine guidelines on preoperative screening and assessment of adult patients with obstructive sleep apnea. Anesth Analg. 2016;123(2):452–473. doi:10.1213/ANE.0000000000001416.
- Gross JB, Bachenberg KL, Benumof JL, et al. Practice guidelines for the perioperative management of patients with obstructive sleep apnea: a report by the American Society of Anesthesiologists Task Force on Perioperative Management of Patients with Obstructive Sleep Apnea. Anesthesiology. 2006;104(5):1081–1093.
- Kamendat J, Dabney BW, McFarland M, Gilbert GE, Richards-Weatherby K. Implementing a clinical practice guideline on opioid-induced advancing sedation and respiratory depression. J Nurs Care Qual. 2020;35(1):13–19. doi:10.1097/NCQ.0000000000000406.
- Kozub E, Uttermark A, Skoog R, Dickey W. Preventing postoperative opioid-induced respiratory depression through implementation of an enhanced monitoring program. J Healthc Qual. 2022;44(1):e7–e14. doi:10.1097/JHQ.0000000000000322.
- Gali B, Whalen FX, Schroeder DR, Gay PC, Plevak DJ. Identification of patients at risk for postoperative respiratory complications using a preoperative obstructive sleep apnea screening tool and postanesthesia care assessment. Anesthesiology. 2009;110(4):869–877. doi:10.1097/ALN.0b013e31819b5d70.
- Weingarten TN, Sprung J. An update on postoperative respiratory depression. Int Anesthesiol Clin. 2022;60(2):8–19. doi:10.1097/AIA.0000000000000362.
- Gordon DB, Pellino TA. Incidence and characteristics of naloxone use in postoperative pain management: a critical examination of naloxone use as a potential quality measure. Pain Manag Nurs. 2005;6(1):30–36. doi:10.1016/j.pmn.2004.12.003.
- Dowell D, Haegerich TM, Chou R. CDC guideline for prescribing opioids for chronic pain—United States, 2016. MMWR Recomm Rep. 2016;65(1):1–49. doi:10.15585/mmwr.rr6501e1.
- Sessler CN, Gosnell MS, Grap MJ, et al. The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med. 2002;166(10):1338–1344. doi:10.1164/rccm.2107138.
- Deljou A, Hedrick SJ, Portner ER, et al. Pattern of perioperative gabapentinoid use and risk for postoperative naloxone administration. Br J Anaesth. 2018;120(4):798–806. doi:10.1016/j.bja.2017.11.113.
- Valencia Morales DJ, Laporta ML, Meehan AM, Schroeder DR, Sprung J, Weingarten TN. Incidence and outcomes of life-threatening events during hospitalization: a retrospective study of patients treated with naloxone. Pain Med. 2022;23(5):878–886. doi:10.1093/pm/pnab310.
- Khelemsky Y, Kothari R, Campbell N, Farnad S. Incidence and demographics of post-operative naloxone administration: a 13-year experience at a major tertiary teaching institution. Pain Phys. 201;18(5):E827–E829. doi:10.36076/ppj.2015/18/E827.
- Rosenfeld DM, Betcher JA, Shah RA, et al. Findings of a naloxone database and its utilization to improve safety and education in a tertiary care medical center. Pain Pract. 2016;16(3):327–333. doi:10.1111/papr.12277.
- Eckstrand JA, Habib AS, Williamson A, et al. Computerized surveillance of opioid-related adverse drug events in perioperative care: a cross-sectional study. Patient Saf Surg. 2009;3(1):18. doi:10.1186/1754-9493-3-18.
- Ramachandran SK, Haider N, Saran KA, et al. Life-threatening critical respiratory events: a retrospective study of postoperative patients found unresponsive during analgesic therapy. J Clin Anesth. 2011;23(3):207–213. doi:10.1016/j.jclinane.2010.09.003.
- Schumann R, Harvey B, Zahedi F, Bonney I. Minute ventilation assessment in the PACU is useful to predict postoperative respiratory depression following discharge to the floor: a prospective cohort study. J Clin Anesth. 2019;52:93–98. doi:10.1016/j.jclinane.2018.09.005.
- Driver CN, Laporta ML, Bergese SD, et al. Frequency and temporal distribution of postoperative respiratory depressive events. Anesth Analg. 2021;132(5):1206–1214. doi:10.1213/ANE.0000000000005478.
- Kor JJ, Sprung J, Khanna AK, Weingarten TN. Continuous monitoring detected respiratory depressive episodes in proximity to adverse respiratory events during the PRODIGY trial. J Patient Saf. 2022;18(8):738–741. doi:10.1097/PTS.0000000000001003.
- Gan TJ. Poorly controlled postoperative pain: prevalence, consequences, and prevention. J Pain Res. 2017;10:2287–2298. doi:10.2147/JPR.S144066.
- McGauvran MM, Ohnuma T, Raghunathan K, et al. Association between gabapentinoids and postoperative pulmonary complications in patients undergoing thoracic surgery. J Cardiothorac Vasc Anesth. 2022;36(8):2295–2302. doi:10.1053/j.jvca.2021.10.003.
- Ohnuma T, Krishnamoorthy V, Ellis AR, et al. Association between gabapentinoids on the day of colorectal surgery and adverse postoperative respiratory outcomes. Ann Surg. 2019;270(6):e65–e67. doi:10.1097/SLA.0000000000003317.
- Ohnuma T, Raghunathan K, Ellis AR, et al. Effects of acetaminophen, NSAIDs, gabapentinoids, and their combinations on postoperative pulmonary complications after total hip or knee arthroplasty. Pain Med. 2020;21(10):2385–2393. doi:10.1093/pm/pnaa017.
- Ohnuma T, Raghunathan K, Moore S, et al. Dose-dependent association of gabapentinoids with pulmonary complications after total hip and knee arthroplasties. J Bone Joint Surg Am. 2020;102(3):221–229. doi:10.2106/JBJS.19.00889.
- Tan HS, Frere Z, Krishnamoorthy V, Ohnuma T, Raghunathan K, Habib AS. Association of gabapentinoid utilization with postoperative pulmonary complications in gynecologic surgery: a retrospective cohort study. Curr Med Res Opin. 2021;37(5):821–828. doi:10.1080/03007995.2021.1900092.
Postoperative opioid-induced respiratory depression or oversedation requiring naloxone treatment in a community hospital: a case series
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.