542
Views
3
CrossRef citations to date
0
Altmetric
Biochemistry & Molecular Biology

Disordered interdomain region of Gins is important for functional tetramer formation to stimulate MCM helicase in Thermoplasma acidophilum

, , , &
Pages 432-438 | Received 09 Sep 2014, Accepted 21 Oct 2014, Published online: 24 Nov 2014

References

  • Ishino Y, Ishino S. Rapid progress of DNA replication studies in Archaea, the third domain of life. Sci. China Life Sci. 2012;55:386–403.10.1007/s11427-012-4324-9
  • Masai H, Matsumoto S, You Z, Yoshizawa-Sugata N, Oda M. Eukaryotic chromosome DNA replication: where, when, and how? Annu. Rev. Biochem. 2010;79:89–130.10.1146/annurev.biochem.052308.103205
  • Mott ML, Berger JM. DNA replication initiation: mechanisms and regulation in bacteria. Nat. Rev. Microbiol. 2007;5:343–354.10.1038/nrmicro1640
  • Leipe DD, Aravind L, Koonin EV. Did DNA replication evolve twice independently? Nucleic Acids Res. 1999;27:3389–3401.10.1093/nar/27.17.3389
  • Kubota Y, Takase Y, Komori Y, Hashimoto Y, Arata T, Kamimura Y, Araki H, Takisawa H. A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication. Genes Dev. 2003;17:1141–1152.10.1101/gad.1070003
  • Gambus A, Jones RC, Sanchez-Diaz A, Kanemaki M, van Deursen F, Edmondson RD, Labib K. GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat. Cell Biol. 2006;8:358–366.10.1038/ncb1382
  • Moyer SE, Lewis PW, Botchan MR. Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. Proc. Natl. Acad. Sci. USA. 2006;103:10236–10241.10.1073/pnas.0602400103
  • Pacek M, Tutter AV, Kubota Y, Takisawa H, Walter JC. Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication. Mol. Cell. 2006;21:581–587.10.1016/j.molcel.2006.01.030
  • Sakakibara N, Kelman LM, Kelman Z. Unwinding the structure and function of the archaeal MCM helicase. Mol. Microbiol. 2009;72:286–296.10.1111/mmi.2009.72.issue-2
  • Makarova KS, Wolf YI, Mekhedov SL, Mirkin BG, Koonin EV. Ancestral paralogs and pseudoparalogs and their role in the emergence of the eukaryotic cell. Nucleic Acids Res. 2005;33:4626–4638.10.1093/nar/gki775
  • Marinsek N, Barry ER, Makarova KS, Dionne I, Koonin EV, Bell SD. GINS, a central nexus in the archaeal DNA replication fork. EMBO Rep. 2006;7:539–545.
  • Yoshimochi T, Fujikane R, Kawanami M, Matsunaga F, Ishino Y. The GINS complex from Pyrococcus furiosus stimulates the MCM helicase activity. J. Biol. Chem. 2008;283:1601–1609.10.1074/jbc.M707654200
  • Ishino S, Fujino S, Tomita H, Ogino H, Takao K, Daiyasu H, Kanai T, Atomi H, Ishino Y. Biochemical and genetical analyses of the three mcm genes from the hyperthermophilic archaeon, Thermococcus kodakarensis. Genes Cells. 2011;16:1176–1189.10.1111/j.1365-2443.2011.01562.x
  • Sanchez-Pulido L, Ponting CP. Cdc45: the missing RecJ ortholog in eukaryotes? Bioinformatics. 2011;27:1885–1888.10.1093/bioinformatics/btr332
  • Li Z, Pan M, Santangelo TJ, Chemnitz W, Yuan W, Edwards JL, Hurwitz J, Reeve JN, Kelman Z. A novel DNA nuclease is stimulated by association with the GINS complex. Nucleic Acids Res. 2011;39:6114–6123.10.1093/nar/gkr181
  • Makarova KS, Koonin EV, Kelman Z. The CMG (CDC45/RecJ, MCM, GINS) complex is a conserved component of the DNA replication system in all archaea and eukaryotes. Biol. Direct. 2012;7:7.10.1186/1745-6150-7-7
  • Ogino H, Ishino S, Mayanagi K, Haugland GH, Birkeland N-K, Yamagishi A, Ishino Y. The GINS complex from the thermophilic archaeon, Thermoplasma acidophilum may function as a homotetramer in DNA replication. Extremophiles. 2011;15:529–539.10.1007/s00792-011-0383-2
  • Ogino H, Ishino S, Haugland GT, Birkeland N-K, Kohda D, Ishino Y. Activation of the MCM helicase from the thermophilic archaeon, Thermoplasma acidophilum by interactions with GINS and Cdc6-2. Extremophiles. 2014;18:915–924.10.1007/s00792-014-0673-6
  • Haugland GT, Sakakibara N, Pey AL, Rollor CR, Birkeland NK, Kelman Z. Thermoplasma acidophilum Cdc6 protein stimulates MCM helicase activity by regulating its ATPase activity. Nucleic Acids Res. 2008;36:5602–5609.10.1093/nar/gkn548
  • Haugland GT, Shin JH, Birkeland NK, Kelman Z. Stimulation of MCM helicase activity by a Cdc6 protein in the archaeon Thermoplasma acidophilum. Nucleic Acids Res. 2006;34:6337–6344.10.1093/nar/gkl864
  • Ishino S, Yamagami T, Kitamura M, Kodera N, Mori T, Sugiyama S, Ando T, Goda N, Tenno T, Hiroaki H, Ishino Y. Multiple interactions of the intrinsically disordered region between the helicase and nuclease domains of the archaeal hef protein. J. Biol. Chem. 2014;289:21627–21639.10.1074/jbc.M114.554998
  • Oyama T, Ishino S, Fujino S, Ogino H, Shirai T, Mayanagi K, Saito M, Nagasawa N, Ishino Y, Morikawa K. Architectures of archaeal GINS complexes, essential DNA replication initiation factors. BMC Biol. 2011;9:28.10.1186/1741-7007-9-28
  • MacNeill S. The haloarchaeal chromosome replication machinery. Biochem. Soc. Trans. 2009;37:108–113.10.1042/BST0370108
  • Costa A, Ilves I, Tamberg N, Petojevic T, Nogales E, Botchan MR, Berger JM. The structural basis for MCM2-7 helicase activation by GINS and Cdc45. Nat. Struct. Mol. Biol. 2011;18:471–477.10.1038/nsmb.2004
  • Kamada K, Kubota Y, Arata T, Shindo Y, Hanaoka F. Structure of the human GINS complex and its assembly and functional interface in replication initiation. Nat. Struct. Mol. Biol. 2007;14:388–396.10.1038/nsmb1231
  • Costa A, Renault L, Swuec P, Petojevic T, Pesavento JJ, Ilves I, MacLellan-Gibson K, Fleck RA, Botchan MR, Berger JM. DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome. eLife 2014;3:e03273.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.