2,231
Views
16
CrossRef citations to date
0
Altmetric
Food & Nutrition Science

Oral administration of Aloe vera gel powder prevents UVB-induced decrease in skin elasticity via suppression of overexpression of MMPs in hairless mice

, , , , , , , & show all
Pages 1416-1424 | Received 30 Nov 2015, Accepted 09 Feb 2016, Published online: 04 Apr 2016

References

  • Cerimele D, Celleno L, Serri F. Physiological changes in ageing skin. Br. J. Dermatol. 1990;122:13–20.10.1111/bjd.1990.122.issue-s35
  • Hwang K, Yi B, Choi K. Molecular mechanisms and in vivo mouse models of skin aging associated with dermal matrix alterations. Lab. Anim. Res. 2011;27:1–8.10.5625/lar.2011.27.1.1
  • Rossetti D, Kielmanowicz MG, Vigodman S, et al. A novel anti-ageing mechanism for retinol: induction of dermal elastin synthesis and elastin fibre formation. Int. J. Cosmet. Sci. 2011;33:62–69.10.1111/ics.2011.33.issue-1
  • Gniadecka M, Nielsen OF, Wessel S, et al. Water and protein structure in photoaged and chronically aged skin. J. Inves. Dermatol. 1998;111:1129–1133.10.1046/j.1523-1747.1998.00430.x
  • Waller JM, Maibach HI. Age and skin structure and function, a quantitative approach (II): protein, glycosaminoglycan, water, and lipid content and structure. Skin. Res. Technol. 2006;12:145–154.10.1111/srt.2006.12.issue-3
  • Nishimori Y, Edwaeds C, Pearse A, et al. Degenerative alterations of dermal collagen fiber bundles in photodamaged human skin and UV-irradiated hairless mouse skin: possible effect on decreasing skin mechanical properties and appearance of wrinkle. J. Invest. Dermatol. 2001;117:1458–1463.
  • Takahashi Y, Ishikawa O, Okada K, et al. Disaccharide analysis of human skin glycosaminoglycans in sun-exposed and sun-protected skin of aged people. J. Dermatol. Sci. 1996;11:129–133.10.1016/0923-1811(95)00430-0
  • Yaar M, Gilchrest BA. Photoageing: mechanism, prevention and therapy. Br. J. Dermatol. 2007;157:874–887.10.1111/bjd.2007.157.issue-5
  • Jenkins G. Molecular mechanisms of skin ageing. Mech. Aging Dev. 2002;123:801–810.10.1016/S0047-6374(01)00425-0
  • Fisher GJ, Voorhees JJ. Molecular mechanisms of photoaging and its prevention by retinoic acid ultraviolet irradiation induce Ap-1-regulated matrix metalloproteinases that degrade human skin in vivo. J. Investig. Dermatol. Symp. Proc. 1998;3:61–68.
  • Fligiel SEG, Varani J, Datta SC, et al. Collagen degradation in aged/photodamaged skin in vivo and after exposure to matrix metalloproteinase-1 in vitro. J. Invest. Dermatol. 2003;120:842–848.10.1046/j.1523-1747.2003.12148.x
  • Quan T, Little E, Quan H, et al. Elevated matrix metalloproteinases and collagen fragmentation in photodamaged human skin: impact of altered extracellular matrix microenvironment on dermal fibroblast function. J. Invest. Dermatol. 2013;133:1362–1366.10.1038/jid.2012.509
  • Verma RP, Hansch C. Matrix metalloproteinases (MMPs): chemical-biological functions and (Q)SARs. Bioog. Med. Chem. 2007;15:2223–2268.10.1016/j.bmc.2007.01.011
  • Reynolds T, Dweck AC. Aloe vera leaf gel: a review update. J. Ethnopharmacol. 1999;68:3–37.10.1016/S0378-8741(99)00085-9
  • Hamman JH. Composition and applications of Aloe vera leaf gel. Molecules. 2008;13:1599–1616.10.3390/molecules13081599
  • Rodríguez ER, Martín JD, Romero CD. Aloe vera as a functional ingredient in foods. Crit. Rev. Food Sci. Nutrition. 2010;50:305–326.10.1080/10408390802544454
  • Maenthaisong R, Chaiyakunapruk N, Niruntraporn S, et al. The efficacy of Aloe vera used for burn wound healing: a systematic review. Burns. 2007;33:713–718.10.1016/j.burns.2006.10.384
  • Chithra P, Sajithlal GB, Chandrakasan G. Influence of Aloe vera on collagen characteristics in healing dermal wounds in rat. Mol. Cell Biochem. 1998;181:71–76.10.1023/A:1006813510959
  • Tanaka M, Misawa E, Yamauchi K, et al. Effects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition in Japanese women. Clin. Cosmet. Investig. Dermatol. 2015;8:95–104.10.2147/CCID
  • Misawa E, Tanaka M, Nabeshima K, et al. Administration of dried aloe vera gel powder reduced body fat mass in diet-induced obesity (DIO) rats. J. Nutr. Sci. Vitaminol. 2012;58:195–201.10.3177/jnsv.58.195
  • Ohshima H, Kinoshita S, Oyobikawa M, et al. Use of cutometer area parameters in evaluating age-related changes in the skin elasticity of the cheek. Skin Res. Tech. 2013;19:e238–e242.10.1111/j.1600-0846.2012.00634.x
  • Rock K, Meusch M, Fuchs N, et al. Estradiol protects dermal hyaluronan/versican matrix during photoaging by release of epidermal growth factor from keratinocytes. J. Biol. Chem. 2012;287:20056–20069.10.1074/jbc.M112.353151
  • Ichihashi M, Ando H, Yoshida M, et al. Photoaging of the skin. Anti. Aging Med. 2009;6:46–59.10.3793/jaam.6.46
  • Rock K, Grandoch M, Majora M, et al. Collagen fragments inhibit hyaluronan synthesis in skin fibroblasts in response to ultraviolet B (UVB): new insights into mechanisms of matrix remodeling. J. Biol. Chem. 2011;286:18268–18276.10.1074/jbc.M110.201665
  • Varani J, Dame MK, Rittie L, et al. Decreased collagen production in chronologically aged skin. Am. J. Pathol. 2006;168:1861–1868.10.2353/ajpath.2006.051302
  • Takema Y, Imokawa G. The effects of UVA and UVB irradiation on the viscoelastic properties of hairless mouse skin in vivo. Dermatology. 1998;196:397–400.10.1159/000017931
  • Jeong H. Skin elasticity and sea polyohenols. Seanol Sci. Center Rev. 2010;1:1–10.
  • Pyun HB, Kim M, Park J, et al. Effects of collagen tripeptide supplement on photoaging and epidermal skin barrier in UVB-exposed hairless mice. Prev. Nutr. Food Sci. 2012;17:245–253.10.3746/pnf.2012.17.4.245
  • Sugimoto S, Ishii Y, Izawa N, et al. Photoprotective effects of Bifidobacterium breve supplementation against skin damage induced by ultraviolet irradiation in hairless mice. Photodermathol. Photo. 2012;28:312–319.10.1111/phpp.2012.28.issue-6
  • Oba C, Ohara H, Morifuji M, et al. Collagen hydrolysate intake improves the loss of epidermal barrier function and skin elasticity induced by UVB irradiation in hairless mice. Photodermathol. Photo. 2013;29:204–211.10.1111/phpp.2013.29.issue-4
  • Gerhardt LC, Lenz A, Spencer ND, et al. Skin-textile friction and skin elasticity in young and aged persons. Skin Res. Technol. 2009;15:288–298.10.1111/srt.2009.15.issue-3
  • Fligiel SEG, Varani J, Datta SC, et al. Collagen degradation in aged/photodamaged skin in vivo and after exposure to matrix metalloproteinase-1 in vitro. J. invest. Dermatol. 2003;120:842–848.10.1046/j.1523-1747.2003.12148.x
  • Yokose U, Hachiya A, Sriwiriyanont P, et al. The endogenous protease inhibitor TIMP-1 mediates protection and recovery from cutaneous photodamage. J. Invest. Dermatol. 2012;132:2800–2809.10.1038/jid.2012.204
  • Inomata S, Matsunaga Y, Amano S, et al. Possible involvement of gelatinase in basement membrane damage and wrinkle formation in chronically ultraviolet B-exposed hairless mouse. J. Invest. Dermatol. 2003;120:128–134.
  • Amano S, Ogura Y, Akutsu N, et al. Protective effect of matrix metalloproteinase inhibitors against epidermal basement membrane damage: skin equivalents partially mimic photoageing process. Br. J. Dermatol. 2005;153:37–46.10.1111/bjd.2005.153.issue-s2
  • Chakraborti S, Mandal M, Das S, et al. Regulation of matrix metalloproteinases: an overview. Mol. Cell Biochem. 2003;253:269–285.10.1023/A:1026028303196
  • Barlaka E, Görbe A, Gáspár R, et al. Activation of PPARβ/δ protects cardiac myocytes from oxidative stress-induced apoptosis by suppressing generation of reactive oxygen/nitrogen species and expression of matrix metalloproteinases. Pharmacol. Res. 2015;95–96:102–110.10.1016/j.phrs.2015.03.008
  • Lee SR, Kim HY, Hong JS, et al. PPARγ agonist pioglitazone reduces matrix metallpproteinase-9 activity and neuronal damage after focal cerebral ischemia. BBRC. 2009;380:17–21.
  • Nomaguchi K, Tanaka M, Misawa E, et al. Aloe vera phytosterols act as ligands for PPAR and improve the expression levels of PPAR target genes in the livers of mice with diet-induced obesity. Obes. Res. Clin. Pract. 2011;5:e190–201.
  • Takahashi Y, Ichikawa O, Okada K, et al. Disaccharide analysis of human skin glycosaminoglycans in sun-exposed and sun-protected skin of aged people. J. Dermal. Sci. 1996;11:129–133.10.1016/0923-1811(95)00430-0
  • Averbeck M, Gedhardt CA, Voigt S, et al. Differential regulation of hyaluronan metabolism in the epidermal and dermal compartments of human skin by UVB irradiation. J. Invest. Dermatol. 2006;127:687–697.
  • Cho S, Lee S, Lee MJ, et al. Dietary Aloe vera supplementation improves facial wrinkles and elasticity and it increases the type I procollagen gene expression in human skin in vivo. Ann. Dermatol. 2009;21:6–11.10.5021/ad.2009.21.1.6
  • Dai G, Freudenberger T, Zipper P, et al. Chronic ultraviolet B irradiation causes loss of hyaluronic acid from mouse dermis because of down-regulation of hyaluronic acid synthases. Am. J. Pathol. 2007;171:1451–1461.10.2353/ajpath.2007.070136
  • Meeran SM, Singh T, Nagy TR, et al. High-fat diet exacerbates inflammation and cell survival signals in the skin of ultraviolet B-irradiated C57BL/6 mice. Toxicol. Appl. Pharm. 2009;241:303–310.10.1016/j.taap.2009.09.003
  • Matsui S, Yamane T, Kobayashi-Hattori K, et al. Ultraviolet B irradiation reduces the expression of adiponectin in ovarial adipose tissues through endocrine actions of calcitonin gene-related peptide-induced serum amyloid A. PLoS ONE. 2014;9:e98040.10.1371/journal.pone.0098040
  • Yamane T, Kobayashi-Hattori K, Oishi Y. Adiponectin promotes hyaluronan synthesis along with increases in hyaluronan synthase 2 transcripts through an AMP-activated protein kinase/peroxisome proliferator-activated receptor-α-dependent pathway in human dermal fibroblasts. Biochem. Biophys. Res. Commun. 2011;415:235–238.10.1016/j.bbrc.2011.09.151
  • Misawa E, Tanaka M, Nomaguchi Kouji, et al. Oral ingestion of Aloe vera phytosterols alters hepatic gene expression profiles and ameliorates obesity-associated metabolic disorders in Zucker diabetic fatty rats. J. Agr. Food Chem. 2012;60:2799–2806.10.1021/jf204465j
  • Kadowaki T, Yamauchi T, Kubota N, et al. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J. Clin. Invest. 2006;116:1784–1792.10.1172/JCI29126
  • Ezure T, Amano S. Adiponectin and leptin up-regulate extracellular matrix production by dermal fibroblasts. BioFactors. 2007;31:229–236.10.1002/biof.v31:3/4

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.