721
Views
3
CrossRef citations to date
0
Altmetric
Biochemistry & Molecular Biology

Effects of pharmacological inhibition of plasminogen binding on liver regeneration in rats

, , , , , & show all
Pages 2105-2111 | Received 05 Jun 2017, Accepted 08 Aug 2017, Published online: 15 Sep 2017

References

  • Rijken DC, Lijnen HR. New insights into the molecular mechanisms of the fibrinolytic system. J Thromb Haemost. 2009;7:4–13.10.1111/jth.2008.7.issue-1
  • Law RH, Caradoc-Davies T, Cowieson N, et al. The X-ray crystal structure of full-length human plasminogen. Cell Rep. 2012;1:185–190.10.1016/j.celrep.2012.02.012
  • Okamoto S, Okamoto U. Amino-methyl cyclohexane-carboxylic acid: AMCHA. Keio J Med. 2009;11:105–115.
  • Naldini L, Vigna E, Bardelli A, et al. Biological activation of pro-HGF (hepatocyte growth factor) by urokinase is controlled by a stoichiometric reaction. J Biol Chem. 1995;270:603–611.10.1074/jbc.270.2.603
  • Yee JA, Yan L, Dominguez JC, et al. Plasminogen-dependent activation of latent transforming growth factor β (TGF β) by growing cultures of osteoblast-like cells. J Cell Physiol. 1993;157:528–534.10.1002/(ISSN)1097-4652
  • McColl B, Baldwin M, Roufail S, et al. Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D. J Exp Med. 2003;198:863–868.
  • Lu P, Takai K, Weaver V, et al. Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harb Perspect Biol. 2011;3:a005058.
  • Barthel D, Schindler S, Zipfel PF. Plasminogen is a complement inhibitor. J. Biol. Chem. 2012;287:18831–18842.10.1074/jbc.M111.323287
  • Godier A, Hunt BJ. Plasminogen receptors and their role in the pathogenesis of inflammatory, autoimmune and malignant disease. J Thromb Haemost. 2013;11:26–34.10.1111/jth.12064
  • Syrovets T, Lunov O, Simmet T. Plasmin as a proinflammatory cell activator. J Leukoc Biol. 2012;92:509–519.10.1189/jlb.0212056
  • Fausto N, Campbell JS, Riehle KJ. Liver regeneration. Hepatology. 2006;43:S45–S53.10.1002/(ISSN)1527-3350
  • Akao M, Hasebe Y, Okumura N, et al. Plasminogen activator-plasmin system potentiates the proliferation of hepatocytes in primary culture. Thromb Res. 2002;107:169–174.10.1016/S0049-3848(02)00258-X
  • Okumura N, Seki T, Ariga T. Cell surface-bound plasminogen regulates hepatocyte proliferation through a uPA-dependent mechanism. Biosci Biotechnol Biochem. 2007;71:1542–1549.10.1271/bbb.70126
  • Okumura N, Koh T, Hasebe Y, et al. A novel function of thrombin-activatable fibrinolysis inhibitor during rat liver regeneration and in growth-promoted hepatocytes in primary culture. J Biol Chem. 2009;284:16553–16561.10.1074/jbc.M109.011452
  • Deutsch DG, Mertz ET. Plasminogen: purification from human plasma by affinity chromatography. Science. 1970;170(3962):1095–1096.10.1126/science.170.3962.1095
  • Higgins GM, Anderson RM. Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal. Arch Pathol. 1931;12:186–202.
  • Ichihara A, Nakamura T, Tanaka K, et al. Biochemical functions of adult rat hepatocytes in primary culture. Ann NY Acad Sci. 1980;349:77–84.10.1111/nyas.1980.349.issue-1
  • Rasband WS. ImageJ. Bethesda, MD: U. S. National Institutes of Health; 1997–2016. Available from: https://imagej.nih.gov/ij/
  • Drixler TA, Vogten JM, Gebbink MFBG, et al. Plasminogen mediates liver regeneration and angiogenesis after experimental partial hepatectomy. Br J Surg. 2003;90:1384–1390.10.1002/(ISSN)1365-2168
  • Bezerra JA, Bugge TH, Melin-Aldana H, et al. Plasminogen deficiency leads to impaired remodeling after a toxic injury to the liver. Proc Nat Acad Sci. 1999;96:15143–15148.10.1073/pnas.96.26.15143
  • Shanmukhappa K, Sabla GE, Degen JL, et al. Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor. BMC Gastroenterology. 2006;6:40.10.1186/1471-230X-6-40
  • Hsiao Y, Zou T, Ling CC, et al. Disruption of tissue-type plasminogen activator gene in mice aggravated liver fibrosis. J Gastroenterol Hepatol. 2008;23:e258–e264.10.1111/jgh.2008.23.issue-7pt2
  • Von Montfort C, Beier JI, Kaiser JP, et al. PAI-1 plays a protective role in CCl4-induced hepatic fibrosis in mice: role of hepatocyte division. Am J Physiol Gastrointest Liver Physiol. 2010;298(5):G657–G666.10.1152/ajpgi.00107.2009
  • Okada K, Ueshima S, Imano M, et al. The regulation of liver regeneration by the plasmin/α2-antiplasmin system. J Hepatol. 2004;40(1):110–116.10.1016/j.jhep.2003.09.016
  • Stewart AG, Xia YC, Harris T, et al. Plasminogen-stimulated airway smooth muscle cell proliferation is mediated by urokinase and annexin A2, involving plasmin-activated cell signalling. Br J Pharmacol. 2013;170(7):1421–1435.10.1111/bph.12422
  • Mars WM, Zarnegar R, Michalopoulos GK. Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA. Am J Pathol. 1993;143(3):949–958.
  • Mars WM, Liu ML, Kitson RP, et al. Immediate early detection of urokinase receptor after partial hepatectomy and its implications for initiation of liver regeneration. Hepatology. 1995;21(6):1695–1701.
  • Kim TH, Mars WM, Stolz DB, et al. Extracellular matrix remodeling at the early stages of liver regeneration in the rat. Hepatology. 1997;26:896–904.10.1002/(ISSN)1527-3350
  • Shen Y, Guo Y, Mikus P, et al. Plasminogen is a key proinflammatory regulator that accelerates the healing of acute and diabetic wounds. Blood. 2012;119(24):5879–5887.10.1182/blood-2012-01-407825
  • Kawao N, Nagai N, Ishida C, et al. Plasminogen is essential for granulation tissue formation during the recovery process after liver injury in mice. J Thromb Haemost. 2010;8(7):1555–1566.10.1111/(ISSN)1538-7836
  • Kawao N, Nagai N, Okada K, et al. Role of plasminogen in macrophage accumulation during liver repair. Thromb Res. 2010;125(5):e214–e221.10.1016/j.thromres.2009.12.009
  • Kawao N, Nagai N, Tamura Y, et al. Urokinase-type plasminogen activator and plasminogen mediate activation of macrophage phagocytosis during liver repair in vivo. Thromb Haemost. 2012;107(4):749–759.10.1160/TH11-08-0567
  • Kawao N, Nagai N, Tamura Y, et al. Urokinase-type plasminogen activator contributes to heterogeneity of macrophages at the border of damaged site during liver repair in mice. Thromb Haemost. 2011;105(5):892–900.10.1160/TH10-08-0516
  • Das R, Ganapathy S, Settle M, et al. Plasminogen promotes macrophage phagocytosis in mice. Blood. 2014;124(5):679–688.10.1182/blood-2014-01-549659

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.