462
Views
1
CrossRef citations to date
0
Altmetric
Award Review

Chemistry and biology for the small molecules targeting characteristics of cancer cells

Pages 10-19 | Received 02 Jul 2018, Accepted 22 Aug 2018, Published online: 24 Sep 2018

References

  • Collett MS, Purchio AF, Erikson RL. Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine. Nature. 1980 May 15;285(5761):167–169. PubMed PMID: 6246443.
  • Ushiro H, Cohen S. Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes. J Biol Chem. 1980 Sep 25;255(18):8363–8365. PubMed PMID: 6157683.
  • Pike LJ, Bowen-Pope DF, Ross R, et al. Characterization of platelet-derived growth factor-stimulated phosphorylation in cell membranes. J Biol Chem. 1983 Aug 10;258(15):9383–9390. PubMed PMID: 6192129.
  • Heldin CH, Ek B, Ronnstrand L. Characterization of the receptor for platelet-derived growth factor on human fibroblasts. Demonstration of an intimate relationship with a 185,000-Dalton substrate for the platelet-derived growth factor-stimulated kinase. J Biol Chem. 1983 Aug 25;258(16):10054–10061. PubMed PMID: 6309764.
  • Umezawa H, Imoto M, Sawa T, et al. Studies on a new epidermal growth factor-receptor kinase inhibitor, erbstatin, produced by MH435-hF3. J Antibiot (Tokyo). 1986 Jan;39(1):170–173. PubMed PMID: 3005217.
  • Nakamura H, Iitaka Y, Imoto M, et al. The structure of an epidermal growth factor-receptor kinase inhibitor, erbstatin. J Antibiot (Tokyo). 1986 Feb;39(2):314–315. PubMed PMID: 3007417.
  • Imoto M, Umezawa K, Komuro K, et al. Antitumor activity of erbstatin, a tyrosine protein kinase inhibitor. Jpn J Cancer Res. 1987 Apr;78(4):329–332. PubMed PMID: 3108212.
  • Imoto M, Morii T, Deguchi A, et al. Involvement of phosphatidylinositol synthesis in the regulation of S phase induction. Exp Cell Res. 1994 Nov;215(1):228–233. PubMed PMID: 7957673.
  • Imoto M, Kakeya H, Sawa T, et al. Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy, isolation, and characterization. J Antibiot (Tokyo). 1993 Sep;46(9):1342–1346. PubMed PMID: 8226312.
  • Zenitani S, Tashiro S, Shindo K, et al. Gerfelin, a novel inhibitor of geranylgeranyl diphosphate synthase from Beauveria felina QN22047. I. Taxonomy, fermentation, isolation, and biological activities. J Antibiot (Tokyo). 2003 Jul;56(7):617–621. PubMed PMID: 14513904.
  • Islam MS, Kitagawa M, Imoto M, et al. Synthesis of gerfelin and related analogous compounds. Biosci Biotechnol Biochem. 2006 Oct;70(10):2523–2528. PubMed PMID: 17031062.
  • Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin. 2008 Mar–Apr;58(2):71–96. PubMed PMID: 18287387.
  • Heinlein CA, Chang C. Androgen receptor in prostate cancer. Endocr Rev. 2004 Apr;25(2):276–308. . PubMed PMID: 15082523.
  • Tran C, Ouk S, Clegg NJ, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science. 2009 May 8;324(5928):787–790. PubMed PMID: 19359544; PubMed Central PMCID: PMC2981508.
  • Korpal M, Korn JM, Gao X, et al. An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide). Cancer Discov. 2013 Sep;3(9):1030–1043. PubMed PMID: 23842682.
  • Saito S, Fujimaki T, Panbangred W, et al. Antarlides: a new type of Androgen Receptor (AR) antagonist that overcomes resistance to AR-targeted therapy. Angew Chem Int Ed Engl. 2016 Feb 18;55(8):2728–2732. PubMed PMID: 26805525.
  • Saito S, Fujimaki T, Panbangred W, et al. Antarlides F-H, new members of the antarlide family produced by Streptomyces sp. BB47. J Antibiot (Tokyo). 2017 May;70(5):595–600. PubMed PMID: 28174422.
  • Takemoto Y, Watanabe H, Uchida K, et al. Chemistry and biology of moverastins, inhibitors of cancer cell migration, produced by Aspergillus. Chem Biol. 2005 Dec;12(12):1337–1347. PubMed PMID: 16356851.
  • Sawada M, Kubo S, Matsumura K, et al. Synthesis and anti-migrative evaluation of moverastin derivatives. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1385–1389. PubMed PMID: 21306898.
  • Kobayashi H, Ogura Y, Sawada M, et al. Involvement of 14-3-3 proteins in the second epidermal growth factor-induced wave of Rac1 activation in the process of cell migration. J Biol Chem. 2011 Nov 11;286(45):39259–39268. PubMed PMID: 21868386; PubMed Central PMCID: PMC3234750.
  • Igarashi Y, Miyanaga S, Onaka H, et al. Revision of the structure assigned to the antibiotic BU-4664L from Micromonopora. J Antibiot (Tokyo). 2005 May;58(5):350–352. PubMed PMID: 16060388.
  • Peppelenbosch MP, Tertoolen LG, den Hertog J, et al. Epidermal growth factor activates calcium channels by phospholipase A2/5-lipoxygenase-mediated leukotriene C4 production. Cell. 1992 Apr 17;69(2):295–303. PubMed PMID: 1314702.
  • Jones TR, Zamboni R, Belley M, et al. Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist. Can J Physiol Pharmacol. 1989 Jan;67(1):17–28. PubMed PMID: 2540892.
  • Tate KM, Lee C, Edelman S, et al. Interactions among polymorphic and conserved residues in MHC class II proteins affect MHC-peptide conformation and T cell recognition. Int Immunol. 1995 May;7(5):747–761. PubMed PMID: 7547702.
  • Magi S, Takemoto Y, Kobayashi H, et al. 5-lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation. Cancer Sci. 2014 Mar;105(3):290–296. PubMed PMID: 24350867; PubMed Central PMCID: PMC4317946.
  • Magi S, Tashiro E, Imoto M. A chemical genomic study identifying diversity in cell migration signaling in cancer cells. Sci Rep. 2012;2:823. PubMed PMID: 23139868; PubMed Central PMCID: PMC3492869.
  • Sanz-Moreno V, Gadea G, Ahn J, et al. Rac activation and inactivation control plasticity of tumor cell movement. Cell. 2008 Oct 31;135(3):510–523. PubMed PMID: 18984162.
  • Mattila PK, Lappalainen P. Filopodia: molecular architecture and cellular functions. Nat Rev Mol Cell Biol. 2008 Jun 1;9(6):446–454. . PubMed PMID: 18464790; eng.
  • Faix J, Rottner K. The making of filopodia. Curr Opin Cell Biol. 2006 Feb 1;18(1):18–25. . PubMed PMID: 16337369; eng.
  • Bacon C, Lakics V, Machesky L, et al. N-WASP regulates extension of filopodia and processes by oligodendrocyte progenitors, oligodendrocytes, and Schwann cells-implications for axon ensheathment at myelination. Glia. 2007 Jun 1;55(8):844–858. PubMed PMID: 17405146; eng.
  • Shulman Z, Shinder V, Klein E, et al. Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin. Immunity. 2009 Mar 20;30(3):384–396. PubMed PMID: 19268609; eng.
  • Kitagawa M, Ikeda S, Tashiro E, et al. Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A. Chem Biol. 2010 Sep 24;17(9):989–998. PubMed PMID: 20851348.
  • Kitagawa M, Misawa M, Ogawa S, et al. A new, convenient cell-based screening method for small-molecule glycolytic inhibitors. Biosci Biotechnol Biochem. 2011;75(2):367–369. PubMed PMID: 21307586.
  • Ohsumi Y. Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol. 2001 Mar;2(3):211–216. PubMed PMID: 11265251.
  • Yoshimori T. Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun. 2004 Jan 9;313(2):453–458. PubMed PMID: 14684184.
  • Sasazawa Y, Kanagaki S, Tashiro E, et al. Xanthohumol impairs autophagosome maturation through direct inhibition of valosin-containing protein. ACS Chem Biol. 2012 May 18;7(5):892–900. PubMed PMID: 22360440.
  • Tresse E, Salomons FA, Vesa J, et al. VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD. Autophagy. 2010 Feb;6(2):217–227. PubMed PMID: 20104022; PubMed Central PMCID: PMC2929010.
  • Shikata Y, Yoshimaru T, Komatsu M, et al. Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor. Cancer Sci. 2017 Apr;108(4):785–794. PubMed PMID: 28122154; PubMed Central PMCID: PMC5406609.
  • Tsujimoto Y, Cossman J, Jaffe E, et al. Involvement of the bcl-2 gene in human follicular lymphoma. Science. 1985 Jun 21;228(4706):1440–1443. PubMed PMID: 3874430.
  • Wang S, Yang D, Lippman ME. Targeting Bcl-2 and Bcl-XL with nonpeptidic small-molecule antagonists. Semin Oncol. 2003 Oct;30(5 Suppl 16):133–142. PubMed PMID: 14613034.
  • Futamura Y, Sawa R, Umezawa Y, et al. Discovery of incednine as a potent modulator of the anti-apoptotic function of Bcl-xL from microbial origin. J Am Chem Soc. 2008 Feb 13;130(6):1822–1823. PubMed PMID: 18205364.
  • Nagamine N, Shirakawa T, Minato Y, et al. Integrating statistical predictions and experimental verifications for enhancing protein-chemical interaction predictions in virtual screening. PLoS Comput Biol. 2009 Jun;5(6):e1000397. PubMed PMID: 19503826; PubMed Central PMCID: PMC2685987.
  • Nagamine N, Sakakibara Y. Statistical prediction of protein chemical interactions based on chemical structure and mass spectrometry data. Bioinformatics. 2007 Aug 1;23(15):2004–2012. . PubMed PMID: 17510168.
  • Wishart DS, Knox C, Guo AC, et al. DrugBank: a comprehensive resource for in silico drug discovery and exploration [research support, non-U.S. gov’t]. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D668–72. PubMed PMID: 16381955; PubMed Central PMCID: PMC1347430. eng.
  • Menendez JA, Lupu R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer. 2007 Oct;7(10):763–777. . PubMed PMID: 17882277.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.