Comparative analysis of enteroendocrine cells and their hormones between mouse intestinal organoids and native tissues

References

• Mace OJ, Tehan B, Marshall F. Pharmacology and physiology of gastrointestinal enteroendocrine cells. Pharmacol Res Perspect. 2015;3:e00155.
   PubMed Web of Science ®Google Scholar
• Jenny M, Uhl C, Roche C, et al. Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. Embo J. 2002;21:6338–6347.
   PubMed Web of Science ®Google Scholar
• Schonhoff SE, Giel-Moloney M, Leiter AB. Minireview: development and differentiation of gut endocrine cells. Endocrinology. 2004;145:2639–2644.
   PubMed Web of Science ®Google Scholar
• Jiang FX, Li K, Archer M, et al. Differentiation of islet progenitors regulated by nicotinamide into transcriptome-verified beta cells that ameliorate diabetes. Stem Cells. 2017;35:1341–1354.
   PubMed Web of Science ®Google Scholar
• Nakajima C, Kamimoto K, Miyajima K, et al. A method for identifying mouse pancreatic ducts. Tissue Eng Part C Methods. 2018;24:480–485.
   PubMed Web of Science ®Google Scholar
• Baggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology. 2007;132:2131–2157.
   PubMed Web of Science ®Google Scholar
• Hughes CA, Bates T, Dowling RH. Cholecystokinin and secretin prevent the intestinal mucosal hypoplasia of total parenteral nutrition in the dog. Gastroenterology. 1978;75:34–41.
   PubMed Web of Science ®Google Scholar
• Fried M, Erlacher U, Schwizer W, et al. Role of cholecystokinin in the regulation of gastric emptying and pancreatic enzyme secretion in humans. Studies with the cholecystokinin-receptor antagonist loxiglumide. Gastroenterology. 1991;101:503–511.
   PubMed Web of Science ®Google Scholar
• Monteiro MP, Batterham RL. The importance of the gastrointestinal tract in controlling food intake and regulating energy balance. Gastroenterology. 2017;152:1707–1717 e1702.
   PubMed Web of Science ®Google Scholar
• Goldspink DA, Reimann F, Gribble FM. Models and tools for studying enteroendocrine cells. Endocrinology. 2018;159:3874–3884.
   PubMed Web of Science ®Google Scholar
• Moran GW, Leslie FC, Levison SE, et al. Enteroendocrine cells: neglected players in gastrointestinal disorders? Therap Adv Gastroenterol. 2008;1:51–60.
   PubMedGoogle Scholar
• May CL, Kaestner KH. Gut endocrine cell development. Mol Cell Endocrinol. 2010;323:70–75.
   PubMed Web of Science ®Google Scholar
• Park JG, Oie HK, Sugarbaker PH, et al. Characteristics of cell lines established from human colorectal carcinoma. Cancer Res. 1987;47:6710–6718.
   PubMed Web of Science ®Google Scholar
• Rindi G, Grant SG, Yiangou Y, et al. Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expression. Am J Pathol. 1990;136:1349–1363.
   PubMed Web of Science ®Google Scholar
• Drucker DJ, Jin T, Asa SL, et al. Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line. Mol Endocrinol. 1994;8:1646–1655.
   PubMed Web of Science ®Google Scholar
• Barker N, van Es JH, Kuipers J, et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature. 2007;449:1003–1007.
   PubMed Web of Science ®Google Scholar
• Sato T, Vries RG, Snippert HJ, et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature. 2009;459:262–265.
   PubMed Web of Science ®Google Scholar
• Stelzner M, Helmrath M, Dunn JC, et al., N.I.H.I.S.C. Consortium. A nomenclature for intestinal in vitro cultures. Am J Physiol Gastrointest Liver Physiol. 2012;302:G1359–1363.
   PubMed Web of Science ®Google Scholar
• Huch M, Bonfanti P, Boj SF, et al. Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis. Embo J. 2013;32:2708–2721.
   PubMed Web of Science ®Google Scholar
• Huch M, Dorrell C, Boj SF, et al. In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. Nature. 2013;494:247–250.
   PubMed Web of Science ®Google Scholar
• Mahe MM, Aihara E, Schumacher MA, et al. Establishment of gastrointestinal epithelial organoids. Curr Protoc Mouse Biol. 2013;3:217–240.
   PubMedGoogle Scholar
• Aihara E, Mahe MM, Schumacher MA, et al. Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid. Sci Rep. 2015;5:17185.
   PubMed Web of Science ®Google Scholar
• Schneider CA, Rasband WS, Eliceiri KW. NIH Image to ImageJ: 25 years of image analysis. Nat Methods. 2012;9:671–675.
   PubMed Web of Science ®Google Scholar
• Egerod KL, Engelstoft MS, Grunddal KV, et al. A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin. Endocrinology. 2012;153:5782–5795.
   PubMed Web of Science ®Google Scholar
• Reimann F, Habib AM, Tolhurst G, et al. Glucose sensing in L cells: a primary cell study. Cell Metab. 2008;8:532–539.
   PubMed Web of Science ®Google Scholar
• Date Y, Kojima M, Hosoda H, et al. Ghrelin, A novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology. 2000;141:4255–4261.
   PubMed Web of Science ®Google Scholar
• Roth KA, Hertz JM, Gordon JI. Mapping enteroendocrine cell populations in transgenic mice reveals an unexpected degree of complexity in cellular differentiation within the gastrointestinal tract. J Cell Biol. 1990;110:1791–1801.
   PubMed Web of Science ®Google Scholar
• Kopin AS, Wheeler MB, Leiter AB. Secretin: structure of the precursor and tissue distribution of the mRNA. Proc Natl Acad Sci U S A. 1990;87:2299–2303.
   PubMed Web of Science ®Google Scholar
• Habib AM, Richards P, Cairns LS, et al. Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry. Endocrinology. 2012;153:3054–3065.
   PubMed Web of Science ®Google Scholar
• Polak JM, Bloom SR, Kuzio M, et al. Cellular localization of gastric inhibitory polypeptide in the duodenum and jejunum. Gut. 1973;14:284–288.
   PubMed Web of Science ®Google Scholar
• Bloom SR. Hormones of the gastrointestinal tract. Br Med Bull. 1974;30:62–67.
   PubMed Web of Science ®Google Scholar