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Articles

Effect of temporally patterned TNF-α delivery on in vitro osteogenic differentiation of mesenchymal stem cells cultured on biodegradable polymer scaffolds

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Pages 1794-1813 | Received 01 Apr 2013, Accepted 06 May 2013, Published online: 08 Jun 2013

References

  • Mountziaris , PM , Spicer , PP , Kasper , FK and Mikos , AG . 2011 . Harnessing and modulating inflammation in strategies for bone regeneration . Tissue Eng. Part B Rev. , 17 : 393 – 402 .
  • Gerstenfeld , LC , Cullinane , DM , Barnes , GL , Graves , DT and Einhorn , TA . 2003 . Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation . J. Cell. Biochem. , 88 : 873 – 884 .
  • Kolar , P , Schmidt-Bleek , K , Schell , H , Gaber , T , Toben , D , Schmidmaier , G , Perka , C , Buttgereit , F and Duda , GN . 2010 . The early fracture hematoma and its potential role in fracture healing . Tissue Eng. Part B Rev. , 16 : 427 – 434 .
  • Glass , GE , Chan , JK , Freidin , A , Feldmann , M , Horwood , NJ and Nanchahal , J . 2011 . TNF-α promotes fracture repair by augmenting the recruitment and differentiation of muscle-derived stromal cells . Proc. Natl. Acad. Sci. USA. , 108 : 1585 – 1590 .
  • Pape , H-C , Marcucio , R , Humphrey , C , Colnot , C , Knobe , M and Harvey , EJ . 2010 . Trauma-induced inflammation and fracture healing . J. Orthop. Trauma. , 24 : 522 – 525 .
  • Takayanagi , H . 2009 . Osteoimmunology and the effects of the immune system on bone . Nat. Rev. Rheumatol. , 5 : 667 – 676 .
  • Kon , T , Cho , T-J , Aizawa , T , Yamazaki , M , Nooh , N , Graves , DT , Gerstenfeld , LC and Einhorn , TA . 2001 . Expression of osteoprotegerin, receptor activator of NF-κB ligand (osteoprotegrin ligand) and related pro-inflammatory cytokines during fracture healing . J. Bone Miner. Res. , 16 : 1004 – 1014 .
  • Mountziaris , PM and Mikos , AG . 2008 . Modulation of the inflammatory response for enhanced bone tissue regeneration . Tissue Eng. Part B Rev. , 14 : 179 – 186 .
  • Gerstenfeld , LC , Cho , T-J , Kon , T , Aizawa , T , Tsay , A , Fitch , J , Barnes , GL , Graves , DT and Einhorn , TA . 2003 . Impaired fracture healing in the absence of TNF-α signaling: the role of TNF-α in endochondral cartilage resorption . J. Bone Miner. Res. , 18 : 1584 – 1592 .
  • Gerstenfeld , LC , Cho , TJ , Kon , T , Aizawa , T , Cruceta , J , Graves , BD and Einhorn , TA . 2001 . Impaired intramembranous bone formation during bone repair in the absence of tumor necrosis factor-alpha signaling . Cells Tissues Organs. , 169 : 285 – 294 .
  • Bocker , W , Docheva , D , Prall , W , Egea , V , Pappou , E , Rossmann , O , Popov , C , Mutschler , W , Ries , C and Schieker , M . 2008 . IKK-2 is required for TNF-α-induced invasion and proliferation of human mesenchymal stem cells . J. Mol. Med. , 86 : 1183 – 1192 .
  • Crisostomo , PR , Wang , Y , Markel , TA , Wang , M , Lahm , T and Meldrum , DR . 2008 . Human mesenchymal stem cells stimulated by TNF-{alpha}, LPS, or hypoxia produce growth factors by an NF{kappa}B- but not JNK-dependent mechanism . Am. J. Physiol. Cell. Physiol. , 294 : C675 – C682 .
  • Hess , K , Ushmorov , A , Fiedler , J , Brenner , RE and Wirth , T . 2009 . TNF[alpha] promotes osteogenic differentiation of human mesenchymal stem cells by triggering the NF-[kappa]B signaling pathway . Bone. , 45 : 367 – 376 .
  • Ding , J , Ghali , O , Lencel , P , Broux , O , Chauveau , C , Devedjian , JC , Hardouin , P and Magne , D . 2009 . TNF-[alpha] and IL-1[beta] inhibit RUNX2 and collagen expression but increase alkaline phosphatase activity and mineralization in human mesenchymal stem cells . Life Sci. , 84 : 499 – 504 .
  • Paula-Silva , FWG , Ghosh , A , Silva , LAB and Kapila , YL . 2009 . TNF-{alpha} promotes an odontoblastic phenotype in dental pulp cells . J. Dent. Res. , 88 : 339 – 344 .
  • Mountziaris , PM , Tzouanas , SN and Mikos , AG . 2010 . Dose effect of tumor necrosis factor-[alpha] on in vitro osteogenic differentiation of mesenchymal stem cells on biodegradable polymeric microfiber scaffolds . Biomaterials. , 31 : 1666 – 1675 .
  • Lacey , DC , Simmons , PJ , Graves , SE and Hamilton , JA . 2009 . Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation . Osteoarthritis Cartilage. , 17 : 735 – 742 .
  • Lin , C-C , Metters , AT and Anseth , KS . 2009 . Functional PEG-peptide hydrogels to modulate local inflammation induced by the pro-inflammatory cytokine TNF[alpha] . Biomaterials. , 30 : 4907 – 4914 .
  • Balga , R , Wetterwald , A , Portenier , J , Dolder , S , Mueller , C and Hofstetter , W . 2006 . Tumor necrosis factor-alpha: alternative role as an inhibitor of osteoclast formation in vitro . Bone. , 39 : 325 – 335 .
  • Iqbal , J , Sun , L , Kumar , TR , Blair , HC and Zaidi , M . 2006 . Follicle-stimulating hormone stimulates TNF production from immune cells to enhance osteoblast and osteoclast formation . Proc. Natl. Acad. Sci. USA. , 103 : 14925 – 14930 .
  • Mountziaris , PM , Tzouanas , SN and Mikos , AG . 2012 . The interplay of bone-like extracellular matrix and TNF-α signaling on in vitro osteogenic differentiation of mesenchymal stem cells . J. Biomed. Mater. Res A. , 100A : 1097 – 1106 .
  • Pham , QP , Sharma , U and Mikos , AG . 2006 . Electrospinning of polymeric nanofibers for tissue engineering applications: a review . Tissue Eng. , 12 : 1197 – 1211 .
  • Pham , QP , Sharma , U and Mikos , AG . 2006 . Electrospun poly(epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration . Biomacromolecules. , 7 : 2796 – 2805 .
  • Datta , N , Holtorf , HL , Sikavitsas , VI , Jansen , JA and Mikos , AG . 2005 . Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells . Biomaterials. , 26 : 971 – 977 .
  • Pham , QP , Kasper , FK , Baggett , LS , Raphael , RM , Jansen , JA and Mikos , AG . 2008 . The influence of the in vitro generated bone-like extracellular matrix on osteoblastic gene expression of marrow stromal cells . Biomaterials. , 29 : 2729 – 2739 .
  • Prockop , DJ . 1997 . Marrow stromal cells as stem cells for nonhematopoietic tissues . Science. , 276 : 71 – 74 .
  • Jaiswal , N , Haynesworth , SE , Caplan , AI and Bruder , SP . 1997 . Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro . J. Cell. Biochem. , 64 : 295 – 312 .
  • Merchant , FA and Periasamy , A . 2008 . “ Correction using calibration images ” . In Microscope Image Processing , Edited by: Wu , Q , Merchant , FA and Castleman , KR . 258 Burlington , VT : Elsevier .
  • Lu Z, Wang G, Dunstan CR, Chen Y, Lu WY-R, Davies B, Zreiqat H. Activation and promotion of adipose tissue-derived mesenchymal stem cells by tumour necrosis factor-alpha preconditioning for bone tissue engineering. J Cell Physiol. 2013;228:1737–1744.
  • Briolay , A , Lencel , P , Bessueille , L , Caverzasio , J , Buchet , R and Magne , D . 2013 . Autocrine stimulation of osteoblast activity by Wnt5a in response to TNF-alpha in human mesenchymal stem cells . Biochem. Biophys. Res. Commun. , 430 : 1072 – 1077 .
  • Lu , Z , Wang , G , Dunstan , CR and Zreiqat , H . 2012 . Short-term exposure to tumor necrosis factor-alpha enables human osteoblasts to direct adipose tissue-derived mesenchymal stem cells into osteogenic differentiation . Stem Cells Dev. , 21 : 2420 – 2429 .
  • Martins , AM , Pham , QP , Malafaya , PB , Sousa , RA , Gomes , ME , Raphael , RM , Kasper , FK , Reis , RL and Mikos , AG . 2009 . The role of lipase and a-amylase in both the degradation of starch/poly(e-caprolactone) fiber meshes and the osteogenic differentiation of cultured marrow stromal cells . Tissue Eng. Part A. , 15 : 295 – 305 .
  • Yang , W , Yang , F , Wang , Y , Both , SK and Jansen , JA . 2013 . In vivo bone generation via the endochondral pathway on three-dimensional electrospun fibers . Acta Biomater. , 9 : 4505 – 4512 .
  • Peter , SJ , Liang , CR , Kim , DJ , Widmer , MS and Mikos , AG . 1998 . Osteoblastic phenotype of rat marrow stromal cells cultured in the presence of dexamethasone, beta-glycerolphosphate, and L-ascorbic acid . J. Cell. Biochem. , 71 : 55 – 62 .
  • Cheng , SL , Yang , JW , Rifas , L , Zhang , SF and Avioli , LV . 1994 . Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone . Endocrinology. , 134 : 277 – 286 .
  • Rundle , CH , Wang , H , Yu , H , Chadwick , RB , Davis , EI , Wegedal , JE , Lau , K-HW , Mohan , S , Ryaby , JT and Baylink , DJ . 2006 . Microarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repair . Bone. , 38 : 521 – 529 .
  • Hecht , J , Kuhl , H , Haas , SA , Bauer , S , Poustka , AJ , Lienau , J , Schell , H , Stiege , AC , Seitz , V , Reinhardt , R , Duda , GN , Mundolos , S and Robinson , PN . 2006 . Gene identification and analysis of transcripts differentially regulated in fracture healing by EST sequencing in the domestic sheep . BMC Genomics. , 7 : 172
  • Singhatanadgit , W , Salih , V and Olsen , I . 2006 . Bone morphogenetic protein receptors and bone morphogenetic protein signaling are controlled by tumor necrosis factor-[alpha] in human bone cells . Int. J. Biochem. Cell Biol. , 38 ( 10 ) : 1794 – 1807 .

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