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Articles

Fabrication of poly (ϵ-caprolactone) microfiber scaffolds with varying topography and mechanical properties for stem cell-based tissue engineering applications

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Pages 1-17 | Received 15 May 2013, Accepted 30 Jul 2013, Published online: 02 Sep 2013

References

  • Griffith LG, Naughton G. Tissue engineering–current challenges and expanding opportunities. Science. 2002;295:1009–1014.
  • Langer R, Vacanti JP. Tissue engineering. Science. 1993;260:920–926.
  • Davis MW, Vacanti JP. Toward development of an implantable tissue engineered liver. Biomaterials. 1996;17:365–372.
  • Hutmacher DW. Scaffolds in tissue engineering bone and cartilage. Biomaterials. 2000;21:2529–2543.
  • Ko J, Kolehmainen K, Ahmed F, Jun MBG, Willerth SM. Towards high throughput tissue engineering: development of chitosan-calcium phosphate scaffolds for engineering bone tissue from embryonic stem cells American. J. Stem Cells. 2012;1:81–89.
  • Kolehmainen K, Willerth SM. Preparation of 3D fibrin scaffolds for stem cell culture applications. J. Visual. Exp. 2012;61:e3641.
  • MacNeil S. Progress and opportunities for tissue-engineered skin. Nature. 2007;445:874–880.
  • Willerth SM. Neural tissue engineering using embryonic and induced pluripotent stem cells. Stem Cell Res. Ther. 2011;2:17–28.
  • Xie J, Willerth SM, Li X, Macewan MR, Rader A, Sakiyama-Elbert SE, Xia Y. The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages. Biomaterials. 2009;30:354–362.
  • Martino S, D’Angelo F, Armentano I, Kenny JM, Orlacchio A. Stem cell-biomaterial interactions for regenerative medicine. Biotechnol. Adv. 2012;30:338–351.
  • Willerth SM, Sakiyama-Elbert SE. Combining stem cells and biomaterial scaffolds for constructing tissues and cell delivery. StemBook: Cambridge, MA; 2008.
  • Nam YS, Yoon JJ, Park TG. A novel fabrication method of macroporous biodegradable polymer scaffolds using gas foaming salt as a porogen additive. J. Biomed. Mater. Res. 2000;53:1–7.
  • Oh SH, Kang SG, Kim ES, Cho SH, Lee JH. Fabrication and characterization of hydrophilic poly(lactic-co-glycolic acid)/poly(vinyl alcohol) blend cell scaffolds by melt-molding particulate-leaching method. Biomaterials. 2003;24:4011–4021.
  • Pinto AR, Correlo VM, Bhattacharya M, Charbord P, Reis RL, Neves NM. Behaviour of human bone marrow mesenchymal stem cells seeded on fiber bonding chitosan polyester based for bone tissue engineering scaffolds. Tissue Eng. 2006;12:1019–1019.
  • Suh SW, Shin JY, Kim J, Kim J, Beak CH, Kim DI, Kim H, Jeon SS, Choo IW. Effect of different particles on cell proliferation in polymer scaffolds using a solvent-casting and particulate leaching technique. Am. Soc.Artif. Intell. Organs J. 2002;48:460–464.
  • Yoshimoto H, Shin YM, Terai H, Vacanti JP. A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Biomaterials. 2003;24:2077–2082.
  • Xie J, MacEwan MR, Ray WZ, Liu W, Siewe DY, Xia Y. Radially aligned, electrospun nanofibers as dural substitutes for wound closure and tissue regeneration applications. ACS Nano. 2010;4:5027–5036.
  • Xie J, MacEwan MR, Schwartz AG, Xia Y. Electrospun nanofibers for neural tissue engineering. Nanoscale. 2010;2:35–44.
  • Pham QP, Sharma U, Mikos AG. Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Eng. 2006;12:1197–1211.
  • Reneker DH, Yarin AL, Fong H, Koombhongse S. Bending instability of electrically charged liquid jets of polymer solutions in electrospinning. J. Appl. Phys. 2000;87:4531–4547.
  • Reneker DH, Yarin AL, Zussman E, Xu H. Electrospinning of nanofibers from polymer solutions and melts. Adv. Appl. Mech. 2007;41:43–195.
  • Mohtaram NK, Montgomery A, Willerth SM. Biomaterial-based drug delivery systems for the controlled release of neurotrophic factors. Biomed. Mater. 2013;8:1–13.
  • Dalton PD, Grafahrend D, Klinkhammer K, Klee D, Möller M. Electrospinning of polymer melts: phenomenological observations. Polymer. 2007;48:6823–6833.
  • Lyons J, Li C, Ko F. Melt-electrospinning part I: processing parameters and geometric properties. Polymer. 2004;45:7597–7603.
  • Dalton PD, Klinkhammer K, Salber J, Klee D, Möller M. Direct in vitro electrospinning with polymer melts. Biomacromolecules. 2006;7:686–690.
  • Park SH, Kim TG, Kim HC, Yang DY, Park TG. Development of dual scale scaffolds via direct polymer melt deposition and electrospinning for applications in tissue regeneration. Acta Biomater. 2008;4:1198–1207.
  • Larrondo L, Manley RSJ. Electrostatic fiber spinning from polymer melts.3. electrostatic deformation of a pendant drop of polymer melt. J. Polym. Sci., Part B: Polym. Phys. 1981;19:933–940.
  • Larrondo L, Manley RSJ. Electrostatic fiber spinning from polymer melts.2. examination of the flow field in an electrically driven jet. J. Polym. Sci., Part B: Polym. Phys. 1981;19:921–932.
  • Larrondo L, Manley RSJ. Electrostatic fiber spinning from polymer melts.1. experimental-observations on fiber formation and properties. J. Polym. Sci., Part B: Polym. Phys. 1981;19:909–920.
  • Pedicini A, Farris RJ. Mechanical behavior of electrospun polyurethane. Polymer. 2003;44:6857–6862.
  • Lee KH, Kim HY, Ryu YJ, Kim KW, Choi SW. Mechanical behavior of electrospun fiber mats of poly(vinyl chloride)/polyurethane polyblends. J. Polym. Sci., Part B: Polym. Phys. 2003;41:1256–1262.
  • Vats A, Tolley NS, Bishop AE, Polak JM. Embryonic stem cells and tissue engineering: delivering stem cells to the clinic. J. R. Soc. Med. 2005;98:346–350.
  • Willerth SM, Faxel TE, Gottlieb DI, Sakiyama-Elbert SE. The effects of soluble growth factors on embryonic stem cell differentiation inside of fibrin scaffolds. Stem Cells. 2007;25:2235–2244.
  • Lopez-Gonzalez R, Velasco I. Therapeutic potential of motor neurons differentiated from embryonic stem cells and induced pluripotent stem cells. Arch. Med. Res. 2012;43:1–10.
  • Li W, Jiang K, Ding S. Concise review: a chemical approach to control cell fate and function. Stem Cells. 2012;30:61–68.
  • Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell. 2006;126:677–689.
  • Christopherson GT, Song H, Mao HQ. The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation. Biomaterials. 2009;30:556–564.
  • Keung AJ, de Juan-Pardo EM, Schaffer DV, Kumar S. Rho GTPases mediate the mechanosensitive lineage commitment of neural stem cells. Stem Cells. 2011;29:1886–1897.
  • Mahairaki V, Lim SH, Christopherson GT, Xu L, Nasonkin I, Yu C, Mao HQ, Koliatsos VE. Nanofiber matrices promote the neuronal differentiation of human embryonic stem cell-derived neural precursors in vitro. Tissue Eng. Part A. 2011;17:855–863.
  • Dash TK, Konkimalla VB. Poly-epsilon-caprolactone based formulations for drug delivery and tissue engineering: a review. J. Controlled Release. 2012;158:15–33.
  • Subramanian C, Ugbolue SC, Warner SB, Patra PK. The melt electrospinning of polycaprolactone (PCL) ultrafine fibers. Polym.-Based Smart Mater. – Processes Prop. App. 2009;1134:229–234.
  • Qiang-Sun Zheng DBO, Xiong-Tao L, Jing-Jing G. Maintaining embryonic stem cells and induced pluripotent stem cells, embryonic stem cells: the hormonal regulation of pluripotency and embryogenesis. Shanghai: IN TECH 672; 2011.
  • Bain G, Kitchens D, Yao M, Huettner JE, Gottlieb DI. Embryonic stem-cells express neuronal properties in-vitro. Dev. Biol. 1995;168:342–357.
  • Haynes WM. The CRC handbook of chemistry and physics. 93rd ed. Boca Raton (FL): Chemical Rubber Company; 2012.
  • Danner RP, Martin SH. Handbook of polymer solution thermodynamics. New York, NY: Design Institute for Physical Property Data (DIPPR), American Institute of Chemical Engineers; 1993.
  • Huang Z-M, Zhang Y-Z, Kotaki M, Ramakrishna S. A review on polymer nanofibers by electrospinning and their applications in nanocomposites. Compos. Sci. Technol. 2003;63:2223–2253.
  • Croisier F, Duwez A-S, Jérôme C, Léonard AF, van der Werf KO, Dijkstra PJ, Benninkd Croisier ML. Mechanical testing of electrospun PCL fibers. Acta Biomater. 2012;8:218–224.
  • Liao TY, Adanur S, Drean JY. Predicting the mechanical properties of nonwoven geotextiles with the finite element method. Text. Res. J. 1997;67:753–760.
  • Willerth SM, Sakiyama-Elbert SE. Cell therapy for spinal cord regeneration. Adv. Drug Delivery Rev. 2008;60:263–276.
  • Oh S, Brammer KS, Julie Li YS, Teng D, Engler AJ, Chien S, Jin S. Stem cell fate dictated solely by altered nanotube dimension. Proc. Nat. Acad. Sci. U.S.A. 2009;106:2130–2135.
  • Dalton PD, Vaquette C, Farrugia BL, Dargaville TR, Brown TD, Hutmacher DW. Electrospinning and additive manufacturing: converging technologies. Biomaterials. 2013;1:171–185.

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