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Research Article

In vitro bio-interaction responses and hemocompatibility of nano-based linear low-density polyethylene polymer embedded with heterogeneous TiO2/ZnO nanocomposites for biomedical applications

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Pages 1301-1311 | Received 24 Jan 2021, Accepted 11 Apr 2021, Published online: 01 Jun 2021

References

  • Monegro AF, Muppidi V, Regunath H. Hospital acquired infections. In: Monegro AF, Muppidi V, Regunath H, editors. StatPearls. Treasure Island (FL): StatPearls Publishing; 2020. https://www.ncbi.nlm.nih.gov/books/NBK441857/.
  • Palza H. Antimicrobial polymers with metal nanoparticles. Int J Mol Sci. 2015;16(1):2099–2116.
  • Veerachamy S, Yarlagadda T, Manivasagam G, et al. Bacterial adherence and biofilm formation on medical implants: a review. Proc Inst Mech Eng H. 2014;228(10):1083–1099.
  • Bryers JD. Medical biofilms. Biotechnol Bioeng. 2008;100(1):1–18.
  • Ramasamy M, Lee JH, Lee J. Potent antimicrobial and antibiofilm activities of bacteriogenically synthesized gold-silver nanoparticles against pathogenic bacteria and their physiochemical characterizations. J Biomater Appl. 2016;31(3):366–378.
  • Taylor EN, Kummer KM, Durmus NG, et al. Superparamagnetic iron oxide nanoparticles (SPION) for the treatment of antibiotic-resistant biofilms. Small. 2012;8(19):3016–3027.
  • Harun NH, Mydin R, Sreekantan S, et al. The bactericidal potential of LLDPE with TiO2/ZnO nanocomposites against multidrug resistant pathogens associated with hospital acquired infections. J Biomater Sci Polym Ed. 2020;31(14):1757–1769.
  • Saharudin KA, Sreekantan S, Basiron N, et al. Bacteriostatic activity of LLDPE nanocomposite embedded with sol–gel synthesized TiO2/ZnO coupled oxides at various ratios. Polymers. 2018;10(8):878.
  • Saharudin KA, Sreekantan S, Basiron N. 3ZnO/TiO2 coupled oxides LLDPE nanocomposite: effect of various weight percent of sol-gel synthesized catalyst on structural and bacteriostatic activity against S. aureus and E. coli. Biomed J Sci Tech Res. 2018;8:6603–6612.
  • Cai H, You Q, Hu Z, et al. Fabrication and correlation between photoluminescence and photoelectrochemical properties of vertically aligned ZnO coated TiO2 nanotube arrays. Sol Energy Mater Sol Cells. 2014;123:233–238.
  • Hussein AM, Mahoney L, Peng R, et al. Mesoporous coupled ZnO/TiO2 photocatalyst nanocomposites for hydrogen generation. J Renew Sustain Energy. 2013;5(3):033118.
  • Sirelkhatim A, Mahmud S, Seeni A, et al. Review on zinc oxide nanoparticles: antibacterial activity and toxicity mechanism. Nanomicro Lett. 2015;7(3):219–242.
  • Stan MS, Nica IC, Popa M, Chifiriuc MC, et al. Reduced graphene oxide/TiO2 nanocomposites coating of cotton fabrics with antibacterial and self-cleaning properties. J Ind Text. 2019;49(3):277–293.
  • Li S, Zeng J, Yin D, et al. Synergic fabrication of titanium dioxide incorporation into heparin-polyvinyl alcohol nanocomposite: enhanced in vitro antibacterial activity and care of in vivo burn injury. Mater Res Express. 2021.
  • Radwan-Pragłowska J, Janus Ł, Piątkowski M, et al. Hybrid bilayer PLA/chitosan nanofibrous scaffolds doped with ZnO, Fe3O4, and Au nanoparticles with bioactive properties for skin tissue engineering. Polymers. 2020;12(1):159.
  • ISO 10993–5, 2009. Biological evaluation of medical devices – Part 5: tests for in vitro cytotoxicity
  • Ibrahim S, Sabudin S, Sahid S, et al. Bioactivity studies and adhesion of human osteoblast (hFOB) on silicon-biphasic calcium phosphate material. Saudi J Biol Sci. 2016;23(1):S56–S63.
  • Grigolo B, Cavallo C, Desando G, et al. Novel nano-composite biomimetic biomaterial allows chondrogenic and osteogenic differentiation of bone marrow concentrate derived cells. J Mater Sci Mater Med. 2015;26(4):173.
  • Cao P, Li WW, Morris AR, et al. Investigation of the antibiofilm capacity of peptide-modified stainless steel. R Soc Open Sci. 2018;5(3):172165.
  • Liu HY, Du L, Zhao YT, et al. In vitro hemocompatibility and cytotoxicity evaluation of halloysite nanotubes for biomedical application. J Nanomater. 2015;2015:1–9.
  • Kumar V, Sharma N, Maitra SS. In vitro and in vivo toxicity assessment of nanoparticles. Int Nano Lett. 2017;7(4):243–256.
  • Han X, Gelein R, Corson N, et al. Validation of an LDH assay for assessing nanoparticle toxicity. Toxicology. 2011;287(1–3):99–104.
  • Kalińska A, Jaworski S, Wierzbicki M, et al. Silver and copper nanoparticles—an alternative in future mastitis treatment and prevention? Int J Mol Sci. 2019;20(7):1672.
  • Kristjansson RP, Oddsson A, Helgason H, et al. Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase. Nat Commun. 2016;7(1):1–8.
  • Beyerle A, Schulz H, Kissel T, et al. Screening strategy to avoid toxicological hazards of inhaled nanoparticles for drug delivery: the use of a-quartz and nano zinc oxide particles as benchmark. J Phys Conf Ser. 2009;151(1):012034.
  • Kao YY, Chen YC, Cheng TJ, Chiung YM, et al. Zinc oxide nanoparticles interfere with zinc ion homeostasis to cause cytotoxicity. Toxicol Sci. 2012;125(2):462–472.
  • Brunner TJ, Wick P, Manser P, et al. In vitro cytotoxicity of oxide nanoparticles: comparison to asbestos, silica, and the effect of particle solubility. Environ Sci Technol. 2006;40(14):4374–4381.
  • Browning CL, The T, Mason MD, et al. Titanium dioxide nanoparticles are not cytotoxic or clastogenic in human skin cells. J Environ Anal Toxicol. 2014;4(6):1–6.
  • Khan M, Naqvi AH, Ahmad M. Comparative study of the cytotoxic and genotoxic potentials of zinc oxide and titanium dioxide nanoparticles. Toxicol Rep. 2015;2:765–774.
  • Ng AMC, Chan CMN, Guo MY, et al. Antibacterial and photocatalytic activity of TiO2 and ZnO nanomaterials in phosphate buffer and saline solution. Appl Microbiol Biotechnol. 2013;97(12):5565–5573.
  • Babu EP, Subastri A, Suyavaran A, et al. Size dependent uptake and hemolytic effect of zinc oxide nanoparticles on erythrocytes and biomedical potential of ZnO-ferulic acid conjugates. Sci Rep. 2017;7(1):1–12.

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