300
Views
3
CrossRef citations to date
0
Altmetric
Articles

Low deacetylation degree chitosan oligosaccharide protects against IL-1β induced inflammation and enhances autophagy activity in human chondrocytes

, , , , , , , , , & show all
Pages 517-531 | Received 08 Jul 2021, Accepted 20 Oct 2021, Published online: 21 Dec 2021

References

  • Silverwood V, Blagojevic-Bucknall M, Jinks C, et al. Current evidence on risk factors for knee osteoarthritis in older adults: a systematic review and meta-analysis. Osteoarthr Cartil. 2015;23(4):507–515.
  • Brandt KD, Radin EL, Dieppe PA, et al. Yet more evidence that osteoarthritis is not a cartilage disease. Ann Rheum Dis. 2006;65(10):1261–1264.
  • Safiri S, Kolahi A-A, Smith E, et al. Global, regional and national burden of osteoarthritis 1990–2017: a systematic analysis of the global burden of disease study 2017. Ann Rheum Dis. 2020;79(6):819–828.
  • Long H, Zeng X, Liu Q, et al. Burden of osteoarthritis in China, 1990–2017: findings from the global burden of disease study 2017. Lancet Rheumatol. 2020;2(3):e164–172.
  • Gill TM. Do the tenets of late-life disability apply to middle age? Ann Intern Med. 2017;167(11):818–819.
  • Wallace IJ, Worthington S, Felson DT, et al. Knee osteoarthritis has doubled in prevalence since the mid-20th century. Proc Natl Acad Sci USA. 2017;114(35):9332–9336.
  • Hunter DJ, Bierma-Zeinstra S. Osteoarthritis. Lancet (London, England). 2019;393(10182):1745–1759.
  • Martel-Pelletier J, Barr AJ, Cicuttini FM, et al. Osteoarthritis. Nat Rev Dis Primers. 2016;2:16072.
  • Yasuda T. Activation of Akt leading to NF-κB up-regulation in chondrocytes stimulated with fibronectin fragment. Biomed Res. 2011;32(3):209–215.
  • Wang M, Sampson ER, Jin H, et al. MMP13 is a critical target gene during the progression of osteoarthritis. Arthritis Res Ther. 2013;15(1):R5.
  • Scuruchi M, D'Ascola A, Avenoso A, et al. Serglycin as part of IL-1β induced inflammation in human chondrocytes. Arch Biochem Biophys. 2019;669:80–86.
  • Zhang Y, Vasheghani F, Li Y, et al. Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis. Ann Rheum Dis. 2015;74(7):1432–1440.
  • Lodhi G, Kim YS, Hwang JW, et al. Chitooligosaccharide and its derivatives: preparation and biological applications. Biomed Res Int. 2014;2014(1):654913.
  • Azuma K, Osaki T, Minami S, et al. Anticancer and anti-Inflammatory properties of chitin and chitosan oligosaccharides. J Funct Biomater. 2015;6(1):33–49.
  • Mi JC, Park JK, Yong IP. Anti-inflammatory effects of low-molecular weight chitosan oligosaccharides in IgE-antigen complex-stimulated RBL-2H3 cells and asthma model mice. Int Immunopharmacol. 2012;12(2):453–459.
  • Liu X, Xia W, Jiang Q, et al. Chitosan oligosaccharide-N-chlorokojic acid mannich base polymer as a potential antibacterial material. Carbohydr Polym. 2018;182:225–234.
  • Zhang P, Liu W, Peng Y, et al. Toll like receptor 4 (TLR4) mediates the stimulating activities of chitosan oligosaccharide on macrophages. Int Immunopharmacol. 2014;23(1):254–261.
  • Park JK, Chung MJ, Choi HN, et al. Effects of the molecular weight and the degree of deacetylation of chitosan oligosaccharides on antitumor activity. Int J Mol Sci. 2011;12(1):266–277.
  • Andrés E, Albesa-Jové D, Biarnés X, et al. Structural basis of chitin oligosaccharide deacetylation. Angew Chem Int Ed Engl. 2014;53(27):6882–6887.
  • Zhang H, Du Y, Yu X, et al. Preparation of chitooligosaccharides from chitosan by a complex enzyme. Carbohydr Res. 1999;320(3–4):257–260.
  • Zou P, Li K, Liu S, et al. Effect of chitooligosaccharides with different degrees of acetylation on wheat seedlings under salt stress. Carbohydr Polym. 2015;126:62–69.
  • Muanprasat C, Chatsudthipong V. Chitosan oligosaccharide: biological activities and potential therapeutic applications. Pharmacol Ther. 2017;170:80–97.
  • Lu C, Li Y, Hu S, et al. Scoparone prevents IL-1β-induced inflammatory response in human osteoarthritis chondrocytes through the PI3K/akt/NF-κB pathway. Biomed Pharmacother. 2018;106:1169–1174.
  • Wang F, Liu J, Chen X, et al. IL-1β receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes. Arthrit Res Ther. 2019;21(1):1–14.
  • Robinson WH, Lepus CM, Wang Q, et al. Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis. Nat Rev Rheumatol. 2016;12(10):580–592.
  • Xu Q, Liu M, Liu Q, et al. The inhibition of LPS-induced inflammation in RAW264.7 macrophages via the PI3K/akt pathway by highly N-acetylated chitooligosaccharide. Carbohydr Polym. 2017;174:1138–1143.
  • Zhang C, Yu L, Zhou Y, et al. Chitosan oligosaccharides inhibit IL-1 beta-induced chondrocyte apoptosis via the P38 MAPK signaling pathway. Glycoconj J. 2016;33(5):735–744.
  • Zeng GQ, Chen AB, Li W, et al. High MMP-1, MMP-2, and MMP-9 protein levels in osteoarthritis. Genet Mol Res. 2015;14(4):14811–14822.
  • Cook A, Cook J, Stoker A. Metabolic responses of meniscus to IL-1β. J Knee Surg. 2018;31(9):834–840.
  • Vallon R, Freuler F, Desta-Tsedu N, et al. Serum amyloid A (apoSAA) expression is up-Regulated in rheumatoid arthritis and induces transcription of matrix metalloproteinases. J Immunol. 2001;166(4):2801–2807.
  • Mitchell PG, Magna HA, Reeves LM, et al. Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J Clin Invest. 1996;97(3):761–768.
  • Stanton H, Rogerson FM, East CJ, et al. ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro. Nature. 2005;434(7033):648–652.
  • Mead TJ, Apte SS. ADAMTS proteins in human disorders. Matrix Biol. 2018;71–72:225–239.
  • Loeser RF. Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix. Osteoarthr Cartil. 2009;17(8):971–979.
  • Yu L, Chen Y, Tooze SA. Autophagy pathway: cellular and molecular mechanisms. Autophagy. 2018;14(2):207–215.
  • Nakamura S, Yoshimori T. New insights into autophagosome–lysosome fusion. J Cell Sci. 2017;130(7):1209–1216.
  • Musumeci G, Szychlinska A, Mobasheri M. Age-related degeneration of articular cartilage in the pathogenesis of osteoarthritis: molecular markers of senescent chondrocytes. Histol Histopathol. 2015;30(1):1–12.
  • Almonte-Becerril M, Navarro-Garcia F, Gonzalez-Robles A, et al. Cell death of chondrocytes is a combination between apoptosis and autophagy during the pathogenesis of osteoarthritis within an experimental model. Apoptosis. 2010;15(5):631–638.
  • Carames B, Hasegawa A, Taniguchi N, et al. Autophagy activation by rapamycin reduces severity of experimental osteoarthritis. Ann Rheum Dis. 2012;71(4):575–581.
  • Cheng NT, Guo A, Cui YP. Intra-articular injection of torin 1 reduces degeneration of articular cartilage in a rabbit osteoarthritis model. Bone Joint Res. 2016;5(6):218–224.
  • Takayama K, Kawakami Y, Kobayashi M, et al. Local intra-articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritis. Arthrit Res Ther. 2014;16(6):482.
  • Su LJ, Zhang JH, Gomez H, et al. Reactive oxygen species-induced lipid peroxidation in apoptosis, autophagy, and ferroptosis. Oxid Med Cell Longev. 2019;2019:5080843.
  • Rabinowitz JD, White E. Autophagy and metabolism. Science. 2010;330(6009):1344–1348.
  • Jeon H, Im GI. Autophagy in osteoarthritis. Connect Tissue Res. 2017;58(6):497–508.
  • Kabeya Y, Mizushima N, Ueno T, et al. LC3, a mammalian homologue of yeast APG8P, is localized in autophagosome membranes after processing. Embo J. 2000;19(21):5720–5728.
  • Sajadimajd S, Bahrami G, Mohammadi B, et al. Protective effect of the isolated oligosaccharide from rosa canina in STZ-treated cells through modulation of the autophagy pathway. J Food Biochem. 2020;44(10):e13404. https://doi.org/10.1111/jfbc.13404
  • Lin S, Li L, L I. M, et al. Raffinose increases autophagy and reduces cell death in UVB-irradiated keratinocytes. J Photochem Photobiol B. 2019;201:111653.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.