Advanced search
Publication Cover
Ocular Immunology and Inflammation Volume 15, 2007 - Issue 4
Submit an article Journal homepage
60
Views
6
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Urinary Neopterin Levels in Uveitis: Is It a New Activity Marker?

Ali H. Durukan Department of Ophthalmology, Gulhane Military Medical Academy, Ankara, Turkey
, MD,
Volkan Hurmeric Department of Ophthalmology, Gulhane Military Medical Academy, Ankara, Turkey
, MD,
Emin O. Akgul Department of Biochemistry, Gulhane Military Medical Academy, Ankara, Turkey
, MD,
Selim Kilic Department of Epidemiology, Gulhane Military Medical Academy, Ankara, Turkey
, MD &
Mehmet Z. Bayraktar Department of Ophthalmology, Gulhane Military Medical Academy, Ankara, Turkey
, MD
Pages 303-308 | Received 07 Dec 2007, Accepted 14 Mar 2007, Published online: 08 Jul 2009

REFERENCES

  • Fuchs D, Hausen A, Reibnegger G, Werner E R, Wachter H. Neopterin in clinical medicine. Lancet 1988; 8587: 702
  • Havel M, Jakovics A, Teufelsbauer H. Neopterin as a new marker to detect acute rejection after heart transplantation. J. Heart Transplant 1989; 8: 67–70
  • Fuchs D, Weiss G, Wacher H. Neopterin. Biochemistry and clinical use as a marker for cellular immune reactions. Int Arch Allergy Immunol 1993; 101: 1–6
  • Müller T F, Vogl M, Neumann M C, Lange H, Grimm M, Müller M M. Noninvasive monitoring using serum amyloid A and serum neopterin in cardiac transplantation. Clin Chim Acta 1998; 276: 63–74
  • Vrecko K, Staedtler P, Mischak I, Maresch L, Reibnegger G. Periodontitis and concentrations of the cellular immune activation marker neopterin in saliva and urine. Clin Chim Acta 1997; 268: 31–40
  • Fredrikson S, Link H, Eneroth P. CSF neopterin as marker of disease activity in multiple sclerosis. Acta Neurol Scand 1987; 75: 352–355
  • Murr C, Fuith L C, Widner B, Wirleitner B, Baier-Bitterlich G, Fuchs D. Increased neopterin concentrations in patients with cancer: indicator of oxidative stress?. Anticancer Res 1999; 19: 1721–1728
  • Weiss G, Widner B, Zoller H, Schobersberger W, Fuchs D. Immune response and iron metabolism. Br J Anaesth 1998; 81: 6–9
  • Berdowska A, Zwirska-Korczala K. Neopterin measurement in clinical diagnosis. J Clin Pharmacol Ther 2001; 26: 319–329
  • Werner E R, Bichler A, Daxenbichler G. Determination of neopterin in serum and urine. Clin Chem 1987; 33: 62–66
  • Katoh S, Sueoka T, Matsuura S, Sugimoto T. Biopterin and neopterin in human saliva. Life Sci 1989; 54: 2561–2568
  • Furukawa Y, Nishi K, Kondo T, Tanabe K, Mizuno Y. Significance of CSF total neopterin and biopterin in inflammatory neurological diseases. J Neurol Sci 1992; 111: 65–72
  • Rao G N, Cotlier E. Biosynthesis of neopterin, sepiapterin, and biopterin in rat and human ocular tissues. Invest Ophthalmol Vis Sci 1985; 26: 768–770
  • Duch D S, Bowers S W, Woolf J H, Nichol C A. Biopterin cofactor biosynthesis. GTP cyclohydrolase, neopterin and biopterin in tissues and body fluids of mammalian species. Life Sci 1984; 35: 1895–1901
  • Kose O, Arca E, Akgul O, Erbil K. The levels of serum neopterin in Behcet's disease-objective marker of disease activity. J Dermatol Sci 2006; 42: 128–130
  • Abi-Hanna D, Wakefield D. Increased serum neopterin levels in patients with acute anterior uveitis. Curr Eye Res 1988; 7: 497–502
  • Bloch-Michel E, Nussenblatt R B. International Uveitis Study Group recommendations for the evaluation of intraocular inflammatory disease. Am J Ophthalmol 1987; 103: 234–235
  • Criteria for diagnosis of Behcet's disease. International Study Group for Behcet's Disease. Lancet 1990; 8697: 1078–1080
  • Fuchs D, Werner E R, Wachter H. Soluble products of immune activation: neopterin. Manual of Clinical Laboratory Immunology, R R Rose, E C de Macario, J L Fahey, H Fiedman, G M Denn. American Society of Microbiology, Washington, DC 1992; 251–255
  • Lightman S. Uveitis: what do we know and how does it help?. Clin Exp Immunol 2001; 29: 48–51
  • De Vos A F, Hoekzema R, Kijlstra A. Cytokines and uveitis, a review. Curr Eye Res 1992; 11: 581–597
  • Müller M M, Curtius H C, Herold M, Huber C H. Neopterin in clinical practice. Clin Chim Acta 1991; 201: 1–16
  • Elenkov I J, Chrousos G P. Stress hormones, Th1/Th2 patterns, pro/anti-inflammatory cytokines and susceptibility to disease. Trends Endocrinol Metab 1999; 10: 359–368
  • Fuchs D, Hausen A, Kofler M, Kosanowski H, Reibnegger G, Wachter H. Neopterin as an index of immune response in patients with tuberculosis. Lung 1991; 162: 337–346
  • Reibnegger G J, Bichler A H, Dapunt O, et al. Neopterin as a prognostic indicator in patients with carcinoma of the uterine cervix. Cancer Res 1986; 46: 950–955
  • Murr C, Bergant A, Widschwendter M, Heim K, Schrocksnadel H, Fuchs D. Neopterin is an independent prognostic variable in females with breast cancer. Clin Chem 1999; 45: 1998–2004
  • Gurfinkel E P, Scirica B M, Bozovich G, Macchia A, Manos E, Mautner B. Serum neopterin levels and the angiographic extent of coronary arterial narrowing in unstable angina pectoris and in non-Q-wave acute myocardial infarction. Am J Cardiol 1999; 83: 515–518
  • Fuchs D, Weiss G, Wachter H. Neopterin, biochemistry and clinical use as a marker for cellular immune reactions. Int Arch Allergy Immunol 1993; 101: 1–6
  • Keser G, Oksel F, Aksu K, Kabasakal Y, Gumusdis G. Serum neopterin levels in Behcet's syndrome. Clin Rheumatol 2000; 19: 328–329

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.