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Ocular Immunology and Inflammation Volume 27, 2019 - Issue 2
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Original Articles

The Effect of Topical Ganciclovir and Corticosteroid on Cytomegalovirus Corneal Endotheliitis in Korean Patients

Je-Hyung HwangDepartment of Ophthalmology, Sanggye Paik Hospital, Inje University of Korea, College of Medicine, Seoul, South KoreaORCID Iconhttp://orcid.org/0000-0001-8081-7771View further author information
, MD ORCID Icon,
Minji HaDepartment of Ophthalmology and Visual Science, Seoul St. Mary’s Hospital, Catholic Institute for Visual Science, The Catholic University of Korea, College of Medicine, Seoul, South KoreaView further author information
, MD,
Yooyeon ParkDepartment of Ophthalmology and Visual Science, Seoul St. Mary’s Hospital, Catholic Institute for Visual Science, The Catholic University of Korea, College of Medicine, Seoul, South KoreaView further author information
, MD &
So-Hyang ChungDepartment of Ophthalmology and Visual Science, Seoul St. Mary’s Hospital, Catholic Institute for Visual Science, The Catholic University of Korea, College of Medicine, Seoul, South KoreaCorrespondence[email protected]
View further author information
, MD, PhD
Pages 338-344 | Received 15 Feb 2018, Accepted 05 Jun 2018, Published online: 28 Jun 2018

References

  • Koizumi N, Suzuki T, Uno T, et al. Cytomegalovirus as an etiologic factor in corneal endotheliitis. Ophthalmology. 2008;115(2):292–297.e3. doi:10.1016/j.ophtha.2007.04.053.
  • Koizumi N, Yamasaki K, Kawasaki S, et al. Cytomegalovirus in aqueous humor from an eye with corneal endotheliitis. Am J Ophthalmol. 2006;141(3):564–565. doi:10.1016/j.ajo.2005.09.021.
  • Suzuki T, Ohashi Y. Corneal endotheliitis. SeminOphthalmol. 2008;23(4):235–240. doi:10.1080/08820530802111010.
  • Amano S, Oshika T, Kaji Y, Numaga J, Matsubara M, Araie M. Herpes simplex virus in the trabeculum of an eye with corneal endotheliitis. Am J Ophthalmol. 1999;127(6):721–722. doi:10.1016/S0002-9394(99)00018-5.
  • Mimura T, Amano S, Nagahara M, et al. Corneal endotheliitis and idiopathic sudden sensorineural hearing loss. Am J Ophthalmol. 2002;133(5):699–700. doi:10.1016/S0002-9394(02)01410-1.
  • Choi JA, Kim JE, Noh SJ, Kyuong Kim E, Park CK, Paik SY. Enhanced cytomegalovirus infection in human trabecular meshwork cells and its implication in glaucoma pathogenesis. Sci Rep. 2017;7:43349. doi:10.1038/srep43349.
  • Fan NW, Chung YC, Liu YC, Liu CJ, Kuo YS, Lin PY. Long-term topical ganciclovir and corticosteroids preserve corneal endothelial function in cytomegalovirus corneal endotheliitis. Cornea. 2016;35(5):596–601. doi:10.1097/ICO.0000000000000791.
  • Koizumi N, Inatomi T, Suzuki T, et al. Clinical features and management of cytomegalovirus corneal endotheliitis: analysis of 106 cases from the Japan corneal endotheliitis study. Br J Ophthalmol. 2015;99(1):54–58. doi:10.1136/bjophthalmol-2013-304625.
  • Maudgal PC, Missotten L, De Clercq E, Descamps J. Varicella-zoster virus in the human corneal endothelium: a case report. Bull Soc Belge Ophtalmol. 1980;190:71–86.
  • Shimazaki J, Harashima A, Tanaka Y. Corneal endotheliitis with cytomegalovirus infection of corneal stroma. Eye (Lond). 2010;24(6):1105–1107. doi:10.1038/eye.2009.240.
  • Su CC, Wang IJ, Chen WL, Lin CP, His B, Hu FR. Topical ganciclovir treatment in patients with cytomegalovirus endotheliitis receiving penetrating keratoplasty. ClinExpOphtahlmol. 2013;41(4):339–347. doi:10.1111/j.1442-9071.2012.02888.x.
  • Chee SP, Jap A. Treatment outcome and risk factors for visual loss in Cytomegalovirus endotheliitis. Graefes Arch ClinExpOphthalmol. 2012;250(3):383–389. doi:10.1007/s00417-011-1813-7.
  • Wong VW, Chan CK, Leung DY, Lai TY. Long-term results of oral valganciclovir for treatment of anterior segment inflammation secondary to cytomegalovirus infection. ClinOphthalmol. 2012;6:595–600. doi:10.2147/OPTH.S30476.
  • Cannon MJ, Schmid DS, Hyde TB. Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection. Rev Med Virol. 2010;20(4):202–213. doi:10.1002/rmv.655.
  • Ang M, Sng CC, Chee SP, Tan DT, Mehta JS. Outcomes of corneal transplantation for irreversible corneal decompensation secondary to corneal endotheliitis in Asian eyes. Am J Ophthalmol. 2013;156(2):260–266.e2. doi:10.1016/j.ajo.2013.03.020.
  • Kandori M, Inoue T, Takamatsu F, et al. Prevalence and features of keratitis with quantitative polymerase chain reaction positive for cytomegalovirus. Ophthalmology. 2010;117(2):216–222. doi:10.1016/j.ophtha.2009.06.059.
  • Anshu A, Chee SP, Mehta JS, Tan DT. Cytomegalovirus endotheliitis in Descemet’s stripping endothelial keratoplasty. Ophthalmology. 2009;116(4):624–630. doi:10.1016/j.ophtha.2008.10.031.
  • Chee SP, Jap A. Immune ring formation associated with cytomegalovirus endotheliitis. Am J Ophthalmol. 2011;152(3):449–453.e1. doi:10.1016/j.ajo.2011.03.003.
  • Su CC, Hu FR, Wang TH, et al. Clinical outcomes in cytomegalovirus-positive Posner-Schlossman syndrome patients treated with topical ganciclovir therapy. Am J Ophthalmol. 2014;158(5):1024–1031e5. doi:10.1016/j.ajo.2014.08.007.
  • Keorochna N, Choontanom R. Efficacy and safety of an extemporaneous preparation of 2% ganciclovir eye drops in CMV anterior uveitis. BMJ Open Ophthalmol. 2017;2(1):e000061. 2017doi:10.1136/bmjophth-2016-000061.ecollection.

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