The Usefulness of Monocyte-to-High Density Lipoprotein and Neutrophil-to-Lymphocyte Ratio in Diabetic Macular Edema Prediction and Early anti-VEGF Treatment Response

References

• Luo W-J, Zhang W-F. The relationship of blood cell-associated inflammatory indices and diabetic retinopathy: a meta-analysis and systematic review. Int J Ophthalmol. 2019;12:312.
   PubMed Web of Science ®Google Scholar
• Klein R, Klein BE. Diabetic eye disease. Lancet. 1997;350(9072):197–204. doi:10.1016/S0140-6736(97)04195-0.
   PubMed Web of Science ®Google Scholar
• Daruich A, Matet A, Moulin A, et al. Mechanisms of macular edema: beyond the surface. Prog Retin Eye Res. 2018;63:20–68. doi:10.1016/j.preteyeres.2017.10.006.
   PubMed Web of Science ®Google Scholar
• El-Asrar AMA. Role of inflammation in the pathogenesis of diabetic retinopathy. Middle East Afr J Ophthalmol. 2012;19:70.
   PubMedGoogle Scholar
• Semeraro F, Morescalchi F, Cancarini A, Russo A, Rezzola S, Costagliola C. Diabetic retinopathy, a vascular and inflammatory disease: therapeutic implications. Diabetes Metab. 2019;45(6):517–527. doi:10.1016/j.diabet.2019.04.002.
   PubMed Web of Science ®Google Scholar
• Lee R, Wong TY, Sabanayagam C. Epidemiology of diabetic retinopathy, diabetic macular edema and related vision loss. Eye and Vision. 2015;2:1–25.
   Web of Science ®Google Scholar
• Qin B, Ma N, Tang Q, et al. Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) were useful markers in assessment of inflammatory response and disease activity in SLE patients. Mod Rheumatol. 2016;26(3):372–376. doi:10.3109/14397595.2015.1091136.
   PubMed Web of Science ®Google Scholar
• Yue S, Zhang J, Wu J, Teng W, Liu L, Chen L. Use of the monocyte-to-lymphocyte ratio to predict diabetic retinopathy. Int J Environ Res Public Health. 2015;12(8):10009–10019. doi:10.3390/ijerph120810009.
   PubMed Web of Science ®Google Scholar
• Ilhan C, Citirik M, Uzel MM, Kiziltoprak H, Tekin K. The usefulness of systemic inflammatory markers as diagnostic indicators of the pathogenesis of diabetic macular edema. Arq Bras Oftalmol. 2020;83(4):299–304. doi:10.5935/0004-2749.20200051.
   PubMed Web of Science ®Google Scholar
• Murphy AJ, Woollard KJ. High‐density lipoprotein: A potent inhibitor of inflammation. Clin Exp Pharmacol Physiol. 2010;37(7):710–718.doi:10.1111/j.1440-1681.2009.05338.x.
   PubMed Web of Science ®Google Scholar
• Mirza E, Oltulu R, Katipoğlu Z, Mirza GD, Özkağnıcı A. Monocyte/HDL ratio and lymphocyte/monocyte ratio in patients with pseudoexfoliation syndrome. Ocul Immunol Inflamm. 2020;28(1):142–146. doi:10.1080/09273948.2018.1545913.
   PubMed Web of Science ®Google Scholar
• Korkmaz A, Demir M, Unal S, et al. Monocyte-to-high density lipoprotein ratio (MHR) can predict the significance of angiographically intermediate coronary lesions. Int J Cardiovas Acad. 2017;3(1–2):16–20. doi:10.1016/j.ijcac.2017.05.008.
   Google Scholar
• Şatırtav G, Mirza E, Oltulu R, Mirza GD, Kerimoğlu H. Assessment of monocyte/HDL ratio in branch retinal vein occlusion. Ocul Immunol Inflamm. 2020 Apr 2;28(3):463–467. doi:10.1080/09273948.2019.1569244.
   Web of Science ®Google Scholar
• Marathe PH, Gao HX, Close KL. American D iabetes A ssociation S tandards of M edical C are in D iabetes 2017. J Diabetes. 2017;9(4):320–324. doi:10.1111/1753-0407.12524.
   PubMed Web of Science ®Google Scholar
• Bressler NM, Beaulieu WT, Maguire MG, et al. Early response to anti–vascular endothelial growth factor and two-year outcomes among eyes with diabetic macular edema in protocol T. Am J Ophthalmol. 2018;195:93–100. doi:10.1016/j.ajo.2018.07.030.
   PubMed Web of Science ®Google Scholar
• Fujita T, Hemmi S, Kajiwara M, et al. Complement‐mediated chronic inflammation is associated with diabetic microvascular complication. Diabetes Metab Res Rev. 2013;29(3):220–226. doi:10.1002/dmrr.2380.
   PubMed Web of Science ®Google Scholar
• Liu J, Liu X, Li Y, et al. The association of neutrophil to lymphocyte ratio, mean platelet volume, and platelet distribution width with diabetic retinopathy and nephropathy: a meta-analysis. Biosci Rep. 2018;38:3. doi:10.1042/BSR20180172.
   Web of Science ®Google Scholar
• Woo SJ, Ahn SJ, Ahn J, Park KH, Lee K. Elevated systemic neutrophil count in diabetic retinopathy and diabetes: a hospital-based cross-sectional study of 30,793 Korean subjects. Invest Ophthalmol Vis Sci. 2011;52(10):7697–7703. doi:10.1167/iovs.11-7784.
   PubMed Web of Science ®Google Scholar
• Ulu SM, Dogan M, Ahsen A, et al. Neutrophil-to-lymphocyte ratio as a quick and reliable predictive marker to diagnose the severity of diabetic retinopathy. Diabetes Technol Ther. 2013;15(11):942–947. doi:10.1089/dia.2013.0097.
   PubMed Web of Science ®Google Scholar
• Ancuta P, Wang J, Gabuzda D. CD16+ monocytes produce IL‐6, CCL2, and matrix metalloproteinase‐9 upon interaction with CX3CL1‐expressing endothelial cells. J Leukoc Biol. 2006;80(5):1156–1164. doi:10.1189/jlb.0206125.
   PubMed Web of Science ®Google Scholar
• Barter PJ, Baker PW, Rye K-A. Effect of high-density lipoproteins on the expression of adhesion molecules in endothelial cells. Curr Opin Lipidol. 2002;13(3):285–288. doi:10.1097/00041433-200206000-00008.
   PubMed Web of Science ®Google Scholar
• Kanbay M, Solak Y, Unal HU, et al. Monocyte count/HDL cholesterol ratio and cardiovascular events in patients with chronic kidney disease. Int Urol Nephrol. 2014;46(8):1619–1625. doi:10.1007/s11255-014-0730-1.
   PubMed Web of Science ®Google Scholar
• Onalan E. The relationship between monocyte to high-density lipoprotein cholesterol ratio and diabetic nephropathy. Pak J Med Sci. 2019;35(4):1081. doi:10.12669/pjms.35.4.534.
   PubMed Web of Science ®Google Scholar
• Sirakaya E, Duru Z, Kuçuk B, Duru N. Monocyte to high-density lipoprotein and neutrophil-to-lymphocyte ratios in patients with acute central serous chorioretinopathy. Indian J Ophthalmol. 2020;68(5):854. doi:10.4103/ijo.IJO_1327_19.
   PubMed Web of Science ®Google Scholar
• Vural G, Gümüsyayla Ş. Monocyte-to-high density lipoprotein ratio is associated with a decreased compound muscle action potential amplitude in patients with diabetic axonal polyneuropathy. Medicine (Baltimore). 2018;97:42. doi:10.1097/MD.0000000000012857.
   Web of Science ®Google Scholar
• Hu Y, Cheng Y, Xu X, et al. Pretreatment neutrophil-to-lymphocyte ratio predicts prognosis in patients with diabetic macular edema treated with ranibizumab. BMC Ophthalmol. 2019;19(1):194. doi:10.1186/s12886-019-1200-4.
   PubMed Web of Science ®Google Scholar