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Original Articles

Spectrum of Syphilitic Chorioretinitis and Its Evolution Based on Multimodal Imaging

, MDORCID Icon, , MDORCID Icon, , MDORCID Icon, , MDORCID Icon, , MD, PhDORCID Icon & , MD, PhDORCID Icon
Pages 1639-1650 | Received 18 Nov 2020, Accepted 06 May 2021, Published online: 25 May 2021

References

  • Basic and Clinical Science Course. Section 9. Intraocular inflammation and uveitis. Am Acad Ophthalmol. 2011-12;9:242–249.
  • Kiss S, Damico DM, Young LH. Ocular manifestations and treatment of syphilis. Semin Ophthalmol. 2005;20:161–167. doi:10.1080/08820530500232092.
  • Lima LH, De Andrade GC, Vianello S, et al. Multimodal imaging analyses of hyperreflective dot-like lesions in acute syphilitic posterior placoid chorioretinopathy. J Ophthalmic Inflamm Infect. 2017;7:1. doi:10.1186/s12348-016-0119-7.
  • Wilhelmus KR, Yokoyama CM. Syphilitic episcleritis and scleritis. Am J Ophthalmol. 1987;104(6):595–597. doi:10.1016/0002-9394(87)90170-X.
  • Samson CM, Foster CS. Ocular syphilis. Ophthalmology. 1990;97(10):1281–1287. doi:10.1016/S0161-6420(90)32419-3.
  • Pichi F, Neri P. Multimodal imaging patterns of posterior syphilitic uveitis: a review of the literature, laboratory evaluation and treatment. Int Ophthalmol. 2020;40(5):1319–1329. doi:10.1007/s10792-020-01285-9.
  • Fu EX, Geraets RL, Dodds EM, et al. Superficial retinal precipitates in patients with syphilitic retinitis. Retina. 2010;30(7):1135–1143. doi:10.1097/IAE.0b013e3181cdf3ae.
  • De Souza EC, Jalkh AE, Trempe CL, et al. Unusual central chorioretinitis as the first manifestation of early secondary syphilis. Am J Ophthalmol. 1988;105:271–276. doi:10.1016/0002-9394(88)90009-8.
  • Gass JD, Braunstein RA, Chenoweth RG. Acute syphilitic posterior placoid chorioretinitis. Ophthalmology. 1990;97:1288–1297. doi:10.1016/S0161-6420(90)32418-1.
  • Pichi F, Ciardella AP, Cunningham ET, et al. Spectral domain optical coherence tomography findings in patients with acute syphilitic posterior placoid chorioretinopathy. Retina. 2014;34:373–384. doi:10.1097/IAE.0b013e3182993f11.
  • Saleh MG, Campbell JP, Yang P, Lin P. Ultra-wide-field fundus autofluorescence and spectral-domain optical coherence tomography findings in syphilitic outer retinitis. Ophthalmic Surg Lasers Imaging Retina. 2017;48(3):208–215. doi:10.3928/23258160-20170301-03.
  • Lima BR, Mandelcorn ED, Bakshi N, Nussenblatt RB, Sen HN. Syphilitic outer retinopathy. Ocul Immunol Inflamm. 2014;22(1):4–8. doi:10.3109/09273948.2013.841960.
  • Janier M, Hegyi V, Dupin N, et al. European Guideline on the Management of Syphilis. J Eur Acad Dermatol Venereol. 2014;28:1581–1593. doi:10.1111/jdv.12734.
  • Hoang QV, Cunningham ET Jr, Sorenson JA, et al. The “pitchfork sign” a distinctive optical coherence tomography finding in inflammatory choroidal neovascularization. Retina. 2013;33:1049–1055. doi:10.1097/IAE.0b013e31827e25b8.
  • Eandi CM, Neri P, Adelman RA, et al. Acute syphilitic posterior placoid chorioretinitis: report of a case series and comprehensive review of the literature. Retina. 2012;32(9):1915–1941. doi:10.1097/IAE.0b013e31825f3851.
  • Burkholder BM, Leung TG, Ostheimer TA, et al. Spectral domain optical coherence tomography findings in acute syphilitic posterior placoid chorioretinitis. J Ophthalmic Inflamm Infect. 2014;4:2. doi:10.1186/1869-5760-4-2.
  • Tsui E, Gal-Or O, Ghadiali Q, et al. Multimodal imaging adds new insight into acute syphilitic posterior placoid chorioretinitis. Retin Cases Brief Rep. 2017;0:1–6.
  • Wong W, Naing T, Bhargava M, et al. Acute syphilitic posterior placoid chorioretinitis: multimodal imaging and electrophysiologic findings before and after treatment. Retin Cases Brief Rep. 2019;00:1–8.
  • Joseph A, Rogers S, Browning A, et al. Syphilitic acute posterior placoid chorioretinitis in nonimmunocompromised patients. Eye (Lond). 2007;21(8):1114–1119. doi:10.1038/sj.eye.6702504.
  • Huang CH, Kang EYC, Chen KJ, et al. Acute syphilitic posterior placoid chorioretinopathy mimicking central serous chorioretinopathy: a case report. Taiwan J Ophthalmol. 2018;8:176–178. doi:10.4103/tjo.tjo_18_18.
  • Christakopoulos C, Munch IC. The “pitchfork sign” on optical coherence tomography in a case of acute syphilitic posterior placoid chorioretinitis. Acta Ophthalmol. 2019;97:e942–e943. doi:10.1111/aos.14094.
  • Schlaen A, Aquino MP, Ormaechea MS, Couto C, Saravia M. Spectral optical coherence tomography findings in an adult patient with syphilitic bilateral posterior uveitis and unilateral punctate inner retinitis. Am J Ophthalmol Case Rep. 2019;15:100489. doi:10.1016/j.ajoc.2019.100489. eCollection 2019 Sep.
  • Matsumoto Y, Spaide RF. Autofluorescence imaging of acute syphilitic posterior placoid chorioretinitis. Retin Cases Brief Rep. 2007;1:123–127. doi:10.1097/01.iae.0000242759.80833.39.
  • Armstrong BK, Pitcher J, Shah R, et al. The evolution of untreated acute syphilitic posterior placoid chorioretinitis captures by multimodal retinal imaging. Ophthalmic Surg Lasers Imaging Retina. 2014;45:606–609. doi:10.3928/23258160-20141008-02.
  • Baek J, Kim KS, Lee WK. Natural course of untreated acute syphilitic posterior placoid chorioretinitis. Clin Exp Ophthalmol. 2016;44(5):431–433. doi:10.1111/ceo.12679.
  • Carlson JA, Dabiri G, Cribier B, Sell S. The immunopathobiology of syphilis: the manifestations and course of syphilis are determined by the level of delayed-type hypersensitivity. Am J Dermatopathol. 2011;33:433–460. doi:10.1097/DAD.0b013e3181e8b587.

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